[The examination of the color vision disorders].
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Farnsworth 100 Hue test was used to investigate color vision in 100 diabetic patients. Blue Yellow axis dyschromatopsia was found in 66.5% of patients. Such a dyschromatopsia precedes diabetic retinopathy in 55% of patients. Its frequency increased as a function of the increasing severity of diabetic retinopathy. On the other hand, 36% of the patients suffering from dyschromatopsia misinterpreted the self-monitoring (urine and blood) tests. These results suggest that the investigation of color vision may be a useful tool for the early screening of diabetic retinopathy particularly in self-monitoring patients.
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Investigations were carried out in 25 patients with carotid arteries changes. A 2 MHz head was used. Direction of the flow, the average speed and index of pulsation were determined. The results were compared with examinations in 13 healthy subjects. Disturbances of vision were shown by 11 patients (44 p.c.). A normal direction of blood perfusion was observed in 8 arteries (25 p.c.), a reversed one in 22 (69 p.c.), in 2 patients no Doppler's signal could be obtained. In arteries with a reversal flow of blood the authors observed the maximal mean speed and the lowest pulsation index. In neither case did the ophthalmological examinations reveal any embolic material. It seems that visual disturbances in patients with carotid arteries changes may be caused by a change of direction of the blood flow from a normal to a reversed one.
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OBJECTIVE: The purpose was to determine whether preschool children aged 3 years 0 months through 3 years 6 months could be tested with the Random Dot E, Stereo Smile, and Randot Preschool stereoacuity tests, which are random dot stereotests marketed for use with preschoolers. METHODS: A total of 118 children from five Vision In Preschoolers Study Clinical Centers participated. Strabismic children, as determined by the cover test at distance and near, were excluded from this study. Stereopsis was tested on each child using each of the three tests in a variable, balanced order. A child's testability for each test was determined by the ability to complete the nonstereo task (pretest) and the gross stereo task for each stereotest. Proportions of children able to perform each test were compared using statistical methods accommodating multiple measurements per child. RESULTS: Testability of children on the pretest was greater for the Stereo Smile test (91%) than for the Random Dot E test (81%; p = 0.007) or the Randot Preschool test (71%; p < 0.0001) and greater for the Random Dot E test than for the Randot Preschool test (p = 0.02). For all children, testability on the gross stereo task was greater for the Stereo Smile (77%; p < 0.0001) and Random Dot E (74%; p = 0.005) tests than for the Randot Preschool test (56%) but did not differ significantly between the Stereo Smile and Random Dot E tests (p = 0.19). There were no significant differences among the proportion of children able to complete the gross stereo task among those who were testable on the pretest (p > 0.12, all comparisons). CONCLUSIONS: Among preschoolers aged 3 years 0 months through 3 years 6 months, testability differs significantly across the three commercially available random dot stereotests evaluated. The results suggest that two-choice procedures increase testability of young preschoolers.
Mutations of the gene encoding rhodopsin are responsible for 30% of the cases autosomal dominant retinitis pigmentosa. Rhodopsin molecules are key G-coupled transmembrane proteins initiating the visual transduction cascade in rods. These cells are specialized retinal cells allowing the detection of low intensity lights. Mutations in the rhodopsin gene lead to the progressive destruction of rods, clinically translated by night blindness, a progressive bilateral loss of the peripheral visual field, and predominant alterations of the rod component of the electroretinograms. Inherited colour vision deficiencies are mainly caused by alterations of the genes encoding coloured opsins. These proteins are G-coupled receptors specialized in visual transduction in the cones. These sensorial cells are localized in the center of the neural retina where they allow the detection of refined details and chromatic lights. Rearrangements of the genes encoding the green and the red color pigments are responsible for daltonism.
The minimum angular size of a color stimulus required for its discrimination has been ascertained to be a quantitative criterion for evaluating the form and degree of congenital chromatic visual diseases. Unlike individuals with normal color perception who distinguish all basic and intermediate colors despite their saturation, anomalous trichromats discriminate more saturated colors with larger angular sizes of stimuli than those with normal color perception. Mild and moderate anomalous trichromats do not discriminate lowly saturated colors or for this they require the angular sizes tens of times greater those for normal trichromats. Persons with severe chromatic visual diseases (Type A) do not distinguish moderately saturated colors either. On recognizing the color of test objects, anomalous trichomats make the most mistakes in perceiving the green and yellow colors, the fewest mistakes in perceiving the red color. The minimum angular sizes required to distinguish colors, the percent of errors in their discrimination, and the range of vision of safety signs depend on the form and degree of congenital chromatic diseases. This makes it necessary to apply a differential approach to providing jobs that require rapid and accurate color discrimination in persons with the protanomalous forms of chromatic pathology.
Despite increasing medical use of the computer, many clinics have experienced only limited success (or none at all) in computerized registration of patient data. One important reason for this lies in the complicated user interfaces of most programs. The clinician has no time to familiarize himself with the complicated command sequences involved, while necessary acceptance of the new technology by administrative staff is often lacking. This paper shows that computerized registration and interpretation of patient data are well within the bounds of possibility, given the use of newly-developed user-friendly operating systems and suitable personal computers. A concrete example of computerized registration of data in a remedial center is given: a case with squint symptoms for which 176 parameters can be entered.
PURPOSE: Orthoptic screening in the kindergarten is one option to improve early detection of amblyopia in children aged 3 years. The purpose of this study was to analyse the cost-effectiveness of such a screening programme in Germany. METHODS: Based on data from the literature and own experience gained from orthoptic screening in kindergarten a decision-analytic model was developed. According to the model, all children in kindergarten, aged 3 years, who had not been treated for amblyopia before, were subjected to an orthoptic examination. Non-cooperative children were reexamined in kindergarten after one year. Children with positive test results were examined by an ophthalmologist for diagnosis. Effects were measured by the number of newly diagnosed cases of amblyopia, non-obvious strabismus and amblyogenic refractive errors. Direct costs were estimated from a third-party payer perspective. The influence of uncertain model parameters was tested by sensitivity analysis. RESULTS: In the base analysis the cost per orthoptic screening test was DM 15.39. Examination by an ophthalmologist cost DM 71.20. The total cost of the screening programme in all German kindergartens was DM 6.1 million. With a 1.5% age-specific prevalence of undiagnosed cases, a sensitivity of 95% and a specificity of 98%, a total of 4,261 new cases would be detected. The cost-effectiveness ratio was DM 1,421 per case detected. Sensitivity analysis showed considerable influence of prevalence and specificity on the cost-effectiveness ratio. It was more cost-effective to re-screen non-cooperative children in kindergarten than to have them examined by an ophthalmologist straight-away. CONCLUSIONS: The decision-analytic model showed stable results which may serve as a basis for discussion on the implementation of orthoptic screening and for planning a field study.
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