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How definition of "loosening" affects the incidence of loose total hip reconstructions.

Loosening is the most common long-term problem following total hip reconstruction. For many reasons, it is important to identify the loosened total hip reconstruction. For some purposes, radiographic interpretation is the sole or principal determinant in loosening. However, there are inherent problems with such interpretations, and these problems have neither been explored in any detail in the literature nor emphasized. This article is a review of the literature and one of the problems of defining loosening. Interpretations of radiographic criteria of loosening are matters of judgment, but this judgment is not reflected in the descriptions of precisely how radiographs were interpreted. Definitions in the literature, based on lucencies and position changes, influenced the loosening rate by a factor of at least two, and influenced the apparent importance of risk factors affecting the long-term results by as much as two to three times. Thus by merely altering a definition one can alter which factors seem more or less important. The selection of a definition of loosening must be designed to a specific purpose, but data and a rationale should be provided as a basis for its interpretation. In general, descriptions of radiograph interpretation need to be precise and less subjective.

Adult↗

[Rochus, patron saint of physicians and hospitals--a teledermatologic quiz].

The painting "St. Rochus with an angel" by Quinten Massys in the Alte Pinakothek in Munich was utilized for a teledermatological quiz. First, only a detail of the plague bubo on the thigh was sent electronically to all physicians in our department. The answers were correct descriptions, but the interpretations quite heterogeneous. In a second set, the full painting together with the hint- Pinakothek - was given. Now the number of descriptively correct diagnoses was high; one resident knew the name of the featured individual and his diagnosis. This example demonstrates one problem with teledermatology - when viewing a clinical picture, relevant additional information is frequently essential in order to make a correct diagnosis. In addition, this presentation of saint physicians and hospitals, the holy Rochus, better known to those who are under his protection.

Dermatology↗

Research-based practice with women who have had miscarriages.

PURPOSE: To summarize a research-based description of what it is like to miscarry and to recommend an empirically tested theory of caring for women who have experienced miscarriage. DESIGN: The research program included three phases: interpretive theory generation, descriptive survey and instrument development, and experimental testing of a theory-based intervention. METHODS: Research methods included interpretive phenomenology, factor analysis, and ANCOVA. FINDINGS: A theory of caring and a model of what it is like to miscarry were generated, refined, and tested. A case study shows one woman's response to miscarrying and illustrates clinical application of the caring theory. CONCLUSIONS: The Miscarriage Model is a useful framework for anticipating the variety of responses women have to miscarrying. The caring theory is an effective and sensitive guide to clinical practice with women who miscarry.

Abortion, Spontaneous↗

The social construction of target populations and the transformation of prison-based AIDS policy: a descriptive case study.

When interpreting policy changes, it is important to understand the social construction of those whom the policy affects. Policy Design Perspective by Schneider and Ingram (1993) concentrates on the construction of "agents" and "targets" in an attempt to comprehend policy formation and transformation. The following descriptive case study uses this design to assess the evolution of one prison's AIDS policy. This institution's HIV/AIDS policy originally was quite restrictive in nature, but the changing perceptions of the agents and targets allowed a more humanistic approach to emerge in the handling of HIV-positive inmates.

Acquired Immunodeficiency Syndrome↗

Computer-assisted infrared identification of vapor-phase mixture components.

The IRBASE/MIXIR system was originally tested on interpretation of infrared spectra of condensed-phase mixtures. The system has now been adapted to allow interpretation of vapor-phase mixture spectra. The dynamic interpretation capabilities of the system have been expanded to allow runtime manipulation of complete peak lists, allowing generation of the optimum spectral description for the interpretation at hand. The modifications to the system are described, along with the results of testing on actual mixtures of varying complexity.

Artificial Intelligence↗

[New functions and variables to characterize and compare vectorcardiograms (author's transl)].

1. The variability of electrographic data used up to now is too large to discriminate easily between normal and abnormal. 2. This variability is partly caused by errors in the measuring process and its consequences. A sepcial difficulty is found in determining the beginning and the end of QRS, so that instantaneous vector magnitudes related to the starting or ending moment of QRS will have a high variance and therefore a low comparability. Displacements of the heart will play an important role as a source of errors. 3. It therefore seems to be more appropriate to describe structure and changes in time of the vector loop. To this end 3 new functions v, w and u are described, all three invariant towards positional changes of the heart in space. The term v means a time-dependent function describing the first derivative of the length of the instantaneous resulting vector of all electrical sources. The term w indicates the projection of the first derivative of the instantaneous vector into a plane orthogonal to the resulting vector. Therefore, v is dependent on the change of all resulting electrical forces, whereas w is the velocity of the peak of the resulting vector on its way along the vector loop. The interpretation of u is complicated; u is a measure of how much the vector leaves a plane, in which it normally more or less remains; u is therefore a measure for the edgeside view of the vector loop. 4 These data are combined with the well-known vectorial data to form a system of vectorial description. 5 The interpretability of these data in physiological terms is exemplified. The description presented here allows to go back to cardiac processes in the proper sense and to largely elimenate external influences like those of the thoracic shape on the ecg and vcg. 6. This way of describing an ecg is specially adapted to the discrimination of normal and abnormal in preventive tests.

Adult↗

Studies of cancer in migrant populations: methods and interpretation.

The use of descriptive epidemiological data (collected without a view to investigating any specific hypothesis) to study the risk of cancer in populations which have migrated from one country to another is reviewed. Place of birth is treated as the risk factor under study in such analyses, although they vary considerably in complexity depending on the availability of information on other explanatory or confounding variables. The underlying assumption of these studies is that migrants undergo a change in their environment (although the extent of this is rarely documented), so that differences in cancer rates confirm the importance of environmental over genetic determinants of risk. Studies which document risk according to time spent in the new country or to age at migration, or differences between migrants and their offspring, add an extra dimension, interpretable in terms of the degree of lifestyle change, or lability of the cancer to changes in exposure to the relevant determinant. Past studies have frequently used rather simplistic methodology, with insufficient attention to the presence of bias, and a reluctance to use standard epidemiological techniques to control for obvious sources of confounding. Migrant studies are divided into four broad categories, depending on the number of comparison groups (two, or more), the availability of a time dimension, and information on exposures; examples of each are described.

Environmental Exposure↗

Communicating probabilistic information to cancer patients: is there 'noise' on the line?

The objective was to examine the way that cancer patients translate verbal descriptors of probability into numerical estimates. A list of words commonly used on consent forms to describe the likelihood for benefits or risks of therapies was provided to 100 cancer patients. Two formats, paper/pencil or computer, were used to provide the list of words. Two methods, magnitude estimation and linear analogue scaling, were used to obtain probability estimates for each word. In addition, two scenarios were developed to study 'context effects' on numerical interpretations of verbal descriptions of probability. All patients provided numerical values for the words on two occasions, separated by one week, and two interviewers collected the data. Regardless of method or format, each word elicited widely variable numerical interpretations. An ANOVA model, including patient, word, interviewer, time, method and format, indicated that patient and interviewer produced major effects on probability estimates. Agreement between methods and across time was good. Paper/pencil and computer formats yielded similar results. Context effects did not appear to influence the numerical probabilities elicited by the 2 scenarios. It was concluded that, within this group of patients, there was no consensus about numerical meaning of a given word, and that interviewers can systematically influence numerical interpretations. There appears to be a great deal of 'noise' in this particular line of communication between patients and health professionals.

Aged↗

Maternal prenatal, infancy and concurrent predictors of maternal reports of child psychopathology.

RESEARCH on parent perceptions of infant temperament and child maladjustment has evolved from an initial interpretation of parent reports as objective, veridical descriptions of the child to an interpretation of parent reports as social perceptions that reflect both objective qualities of children and personality characteristics of parents (Bates 1983). Evidence that parents' descriptions reflect generalized behavior of their children is provided by modest correlations between parent and teacher reports of child behavior (Becker and Krug 1964; Glidewell et al. 1959; Rutter et al. 1970). Although limited agreement of parents and teachers in descriptions of child behavior might be interpreted as evidence of situational specificity of behavior (Mischel 1968), an alternative interpretation is that characteristics of parents influence their perceptions of child behavior. This longitudinal study tests hypotheses that maternal characteristics during pregnancy and infancy, prior to the development of stable child characteristics, predict mothers' reports of child psychopathology during the kindergarten year.

Child↗

Cultural ergonomics in Ghana, West Africa: a descriptive survey of industry and trade workers' interpretations of safety symbols.

Globalization and technology transfer have led to the diffusion of risk communications to users from cultures that were not initially viewed as the target users. This study examined industry and trade workers' overall impressions of symbols used to convey varying degrees of hazardousness. Six symbols, including symbols from the American National Standards Institute (ANSI) Z535 Standard (ANSI, 1998) and the International Organization for Standardization (ISO) 3864:1984 Standard (ISO, 1984) were selected. With the exception of the SKULL symbol, results showed wide discrepancies between users' perceptions of the symbols and their intended meanings. Implications for cross-cultural research on warning components and risk communications are discussed.

Accidents, Occupational↗

Alternative descriptions of combined diffusive and convective mass transport in hemodialyzer.

Two alternative versions of the mathematical description of the combined diffusive and convective membrane transport in hemodialyzers were compared using the one-dimensional theory of hemodialyzers. The first version is based on the assumption of homogeneity of the membrane. The second version is a widely used "ad hoc" formulation, which can be interpreted as a description of the membrane as tighter at the dialysate side than at the blood side. Theoretical predictions of the increase of dialyzer clearance caused by ultrafiltration, as assessed by transmittance coefficient, were compared to experimental data about transport of small solutes (urea, creatinine, and sodium) as well as middle molecules (vitamin B12) in three types of hollow-fiber hemodialyzer. For one type of dialyzer, the theory assuming the homogeneous membrane yielded the correct predictions for the small solutes. For two other types of dialyzer, the alternative version of the theory was adequate. For vitamin B12, the experimental values of transmittance coefficient were between the values predicted by the two versions of the theory for all three types of hemodialyzer. Thus, the two versions should be considered as a possible adequate description of solute transport in hemodialyzers.

Membranes, Artificial↗

Linear mechanistic models for the dorsal lateral geniculate nucleus of cat probed using drifting-grating stimuli.

Experiments with sinusoidal visual stimuli in the early visual pathway have traditionally been interpreted in terms of descriptive filter models. We present an alternative mechanistic approach for interpretation of this type of data recorded from X cells in the dorsal lateral geniculate nucleus (dLGN) of cat. A general, linear, rate-based mathematical expression for the geniculate transfer ratio, i.e. the ratio between the first-harmonic components of the output of a geniculate relay cell and its retinal input, is derived. In linear theory this ratio is independent of the signal processing occurring at the retinal level. Further, the ratio is straightforwardly accessible in experiments due to the presence of S-potentials, representing the retinal input, in extracellular recordings from dLGN. The expression accounts for feedforward inputs from retina and intrageniculate interneurons as well as feedback inputs from cortex and the thalamic reticular nucleus and can be used to experimentally test different mechanistic models for the geniculate circuitry. Two examples of this are considered: a purely feedforward model incorporating relay cell inputs from retinal ganglion cells and interneurons, and a model including cortical feedback inhibition of relay cells via intrageniculate interneurons.

Animals↗

[Expression as used in journals to describe acute confusional states in intensive care patients].

The language of nursing contains many special expressions which are used daily to describe different care situations. The aim of this study is to identify what expressions are used in the patient records to describe the development of acute confusion (intensive care unit syndrom) among the patients in an intensive care unit, comparing different usages by nurses and doctors to interpret these expressions. Descriptions and opinions about the general condition, awareness and mental status of patients were collected from their records. Twelve of the commonest expressions were chosen, as well as words describing different stages in the development of acute confusion, and the nurses and doctors were requested to write down what the expressions signified to them. The results showed that the expressions most often used, like "restless" (disturbed) and "picky" have been variously interpreted. This may mean that the symptoms of acute confusion are not discovered in time, or that they go completely unnoticed, which will lead to delaying, or neglecting, the implementation of care measures designed to prevent the worsening of the symptoms. Recommendations for coping with this problem include the use of a shared medical mental status, or the adoption by nurses of a common definition of these special expressions.

Acute Disease↗

Perceptive errors in CT colonography.

Published results to date have indicated a good per patient sensitivity of computed tomographic colonography (CTC) for colorectal cancer and for polyps measuring 10 mm or more together with a very good specificity. Sensitivity and specificity for polyps in the range of 6-10 mm are moderate. These results, however, can be achieved only with meticulous attention to technique including adequate colonic distention, and acquisition of supine and prone thin-section computed tomographic (CT) images. Moreover, there is a significant learning curve involved in the interpretation of CTC studies, with performance statistics improving with operator experience. Radiologists must be comfortable in reporting directly from workstation monitors and have access to and be familiar with software for multiplanar and endoluminal reconstructions. In addition to maximize polyp detection and minimize false positive results, reporting radiologists must have a working knowledge of normal colorectal anatomy and pathology on CTC and be familiar with potential pitfalls in interpretation. Besides the description of several possible causes for perceptive errors, also a literature search of perceptive errors in CTC is included in this paper.

Algorithms↗

Descriptive features of gastric ulcers: do endoscopists agree on what they see?

BACKGROUND: Little is known about the interobserver variation between endoscopists on descriptive morphologic features. METHODS: This study describes the agreement among 10 endoscopists on their description of 12 morphologic features, using 10 photographs of gastric ulcers, and on their eventual interpretation. The endoscopists used a form with predefined options for description. RESULTS: Kappa value was on average 0.36 for descriptive features and 0.31 for interpretation. The proportion of endoscopists agreeing on descriptive features was on average 84%, and 81% on interpretations. The chance of an endoscopist describing all 12 morphologic features of an ulcer on a photograph exactly the same as a colleague ranged from 4% to 46% (average 15%). A positive correlation between agreement in description and interpretation (0.75, p < 0.05) was found. CONCLUSIONS: These results indicate a poor agreement between endoscopists in their translation of visual observations into descriptive terms. The positive correlation between agreement in description and interpretation suggests disagreement in description as an important cause for disagreement in interpretation. We believe that the use of more explicit descriptive terms will improve agreement in description and in subsequent interpretation.

Diagnosis, Differential↗