NEUROFIBROMATOSIS AND COARCTATION OF THE ABDOMINAL AORTA WITH RENAL ARTERY INVOLVEMENT.
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Studies of 40 patients with aneurysms of the abdominal aorta, treated surgically, and 152 cadavers of adult persons enabled to state that atherosclerotic aneurysm of the abdominal aorta in vast majority of patients (in 38 of 40) affects its lower portion and is located at the level of the IIId -- Vth lumbar vertebrae. Also, there were found different variants of the anatomical structure of renal arteries and their relationship with the abdominal aorta aneurysms. It is the authors' opinion that a surgeon should be aware of this fact, while acoomplishing surgical procedures, and carefully estimate the value of an accessory vessel in the kidney blood supply, and also reimplant it in the allograft, if possible. It is believed, that if preservation of the mentioned arteries proved to be unfeasible, then either radical operation should be cancelled or the problem should be solved as to the need or rationality of radical operation simultaneously with nephrectomy in unilateral multitude of renal arteries.
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OBJECTIVES: Females develop cardiovascular diseases and abdominal aortic aneurysms later in life than males. In this study we investigated the diameter and compliance of the distal abdominal aorta in healthy females of varying ages. The results were compared with those obtained previously from healthy males in order to assess potential sex-related differences in the aging process of the abdominal aorta. METHODS: An ultrasound phase-locked echo-tracking system was used to determine differences in diameter and pulsatile diameter change of the distal abdominal aorta in 69 Caucasian females from 4 to 74 years. Pressure strain elastic modulus (Ep) and stiffness (beta) were calculated from diameter, pulsatile diameter change and blood pressure obtained by the auscultatory method. Compliance was defined as the inverse of Ep and beta. The pressure dependence of Ep and beta was evaluated in 10 females with intraarterial blood pressure measurement at rest and during isometric exercise. RESULTS: The diameter of the distal abdominal aorta increased not only in the period between the ages of 5 and 25 years, but also by about 24% between 25 and 70 years (p < 0.0001). From about the age of 25 years the diameter was smaller in females than in males (p < 0.01). Ep and beta increased nearly linearly with advancing age in females from 0.18 x 10(5) to 1.17 x 10(5) N/m2 (Ep) and from 1.85 to 8.51 (beta). In males the increase in Ep and beta was greater and exponential in nature (p < 0.001). Ep but not beta increased significantly during blood pressure increase (p < 0.05). Stiffness (beta) may therefore be a more useful index of arterial compliance than Ep. CONCLUSIONS: This investigation demonstrates age and sex-related differences in diameter and compliance in the normal human abdominal aorta and implies that degenerative changes appear later in females than in males.
OBJECTIVES: To study the trend in incidence of aneurysms of the abdominal aorta in The Netherlands during the past two decades. SETTING: The Dutch population from 1972 to 1992. DESIGN: Analysis of all hospital admissions and deaths due to aneurysms of the abdominal aorta. OUTCOME MEASURES: Age adjusted and age specific mortality and discharge rates. In-hospital mortality after surgery upon aneurysms of the abdominal aorta. RESULTS: From 1972 to 1992 age adjusted mortality from aneurysms of the abdominal aorta rose from 3.1 to 8.1 per 100,000 in men, and from 1.4 to 2.2 in women. Age adjusted discharge rates (alive and dead) for non-ruptured abdominal aortic aneurysms increased from 3.7 to 37.6 per 100,000 in men and from 1.2 to 5.5 in women. For ruptured aneurysms, the age adjusted discharge rates increased from 2.4 to 10.3 per 100,000 in men and from 0.7 to 1.7 in women. Age adjusted in-hospital mortality after surgery upon non-ruptured aneurysms was halved from 13% in 1972 to 7% in 1992, mortality after acute repair upon ruptured aneurysms also decreased from 52% in 1972 to 36% in 1992. CONCLUSIONS: There was an impressive increase in the hospital based incidence for aneurysms of the abdominal aorta during the past two decades in The Netherlands. An improved detection rate through ultrasound is probably a major contributor to this increase, but gender differences and the rise in the number of ruptured aneurysms suggest that a real increase in incidence may exist, especially in men. Surgical outcome for both ruptured and non-ruptured aneurysms of the abdominal aorta improved.