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PubMed1981

[Vertebral angiography of cerebellar hemangioblatoma -tumor stain, tumor circulation, CT and angiography in diagnosis(author's transl)].

Tumor "stain" and pathological tumor circulation were investigated mainly by cerebral angiography in 8 patients of cerebellar hemangioblastoma who were hospitalized in the Hokkaido University Hospital and considered to be suitable for this study. The results are presented with some speculation in this paper. (1) Tumor stain was found in all of the 8 cases. (2) Histologically all 8 cases were composed of endothelial cells with numerous vascular channels. The characteristic tumor "stain" in cerebellar hemangioblastoma was supposed to be closely related to the histologic features. (3) Review of the reports published on tumor stain indicates that tumor staining patterns have been classified into 3 to 5 types. Similar items were established in all the classifications. (4) The 8 cases were divided into 4 types: cystic type, cystic and solid type, solid type, and multiple type based on macroscopic natures of the tumor. Tumor staining patterns in angiography were also tentatively classified into types 1 to 4 according to the natures of the tumor. (5) Concerning pathological tumor circulation, (a) the time of appearance of tumor "stain" was long; (b) early filling veins in the tumor were found in 4 of the 8 cases; (c) almost all feeding arteries had one or two branches; (d) arteries originating from meningeal vessels were enlarged in 2 cases and angiography of the external carotid artery was useful for their identification; and (3) draining veins were enlarged more markedly than feeding arteries and were mostly a single superficial vein. (6) CT was performed in 4 of the 8 cases. It was compared with vertebral angiography regarding diagnostic capability in consideration of the published reports. Vertebral angiography was superior to CT in (a) verification of the presence of multiple lesions in cerebellar hemangioblastoma and (b) differential diagnosis between cerebellar astrocytoma and hemangioblastoma.

Adolescent↗

PubMed2004

Magnetic resonance angiography is equivalent to X-ray coronary angiography for the evaluation of coronary arteries in Kawasaki disease.

OBJECTIVES: The purpose of this study was to compare the results of magnetic resonance angiography (MRA) with X-ray coronary angiography (XCA) in a pediatric population. BACKGROUND: Coronary artery abnormalities in Kawasaki disease (KD) develop in about 15% to 25% of young patients, mostly in the form of aneurysms. METHODS: Thirteen patients (12 male), age three to eight years, were studied. The maximal diameter and length of the aneurysm were recorded. Coronary MRA was performed using a 1.5 T Philips Intera CV magnetic resonance scanner with an electrocardiographically triggered pulse sequence. It was a three-dimensional segmented k-space gradient-echo sequence (TE = 2.1 ms, TR = 7.5 ms, flip angle = 30 degrees, slice thickness = 1.5 mm) employing a T2-weighted preparation pre-pulse and a frequency selective fat-saturation pre-pulse. Data acquisition was performed in mid-diastole. All scans were carried out with the patient free breathing using a two-dimensional real-time navigator beam. All patients underwent XCA within a week. RESULTS: In six patients, aneurysms of the coronary arteries were identified, while coronary ectasia alone was present in the remaining seven patients. Magnetic resonance angiography and XCA diagnosis of coronary artery aneurysm agreed completely. Maximal aneurysm diameter and length and ectasia diameter by MRA and XCA were similar. No stenotic lesion was identified by either technique. CONCLUSIONS: In conclusion, MRA is a reliable diagnostic tool, equivalent to XCA for coronary artery aneurysm identification in patients with KD. Magnetic resonance angiography may prove to be of great value for the serial non-invasive evaluation of these patients.

Child↗

PubMed2004

Diagnostic performance of coronary magnetic resonance angiography as compared against conventional X-ray angiography: a meta-analysis.

OBJECTIVES: This study was designed to define the current role of coronary magnetic resonance angiography (CMRA) for the diagnosis of coronary artery disease (CAD). BACKGROUND: Coronary magnetic resonance angiography has been proposed as a promising noninvasive method for diagnosis of CAD, but individual studies evaluating its clinical value have been of limited sample size. METHODS: We identified all studies (MEDLINE and EMBASE) that evaluated CAD by both CMRA and conventional angiography in >/=10 subjects during the period 1991 to January 2004. We recorded true and false positive and true and false negative CMRA assessments for detection of CAD using X-ray angiography as the reference standard. Analysis was done at segment, vessel, and subject level. RESULTS: We analyzed 39 studies (41 separate comparisons). Across 25 studies (27 comparisons) with data on 4,620 segments (993 subjects), sensitivity and specificity for detection of CAD were 73% and 86%, respectively. Vessel-level analyses (16 studies, 2,041 vessels) showed sensitivity 75% and specificity 85%. Subject-level analyses (13 studies, 607 subjects) showed sensitivity 88% and specificity 56%. At the segment level, sensitivity was 69% to 79% for all but the left circumflex (61%) coronary artery; specificity was 82% to 91%. There was considerable between-study heterogeneity, but weighted summary receiver-operating characteristic curves agreed with these estimates. There were no major differences between subgroups based on technical or population characteristics, year of publication, reported blinding, or sample size. CONCLUSIONS: In evaluable segments of the native coronary arteries, CMRA has moderately high sensitivity for detecting significant proximal stenoses and may have value for exclusion of significant multivessel CAD in selected subjects considered for diagnostic catheterization.

Coronary Angiography↗

PubMed2004

Time-resolved magnetic resonance angiography as a noninvasive method to characterize endoleaks: initial results compared with conventional angiography.

PURPOSE: Several types of endoleaks have been described, each with different methods of treatment. Conventional arteriography is widely regarded as the gold standard for the classification of endoleaks. Recently, faster magnetic resonance gradients have allowed for rapid data acquisition and review of vascular studies as a real-time continuous angiogram (time resolved magnetic resonance angiography [TR-MRA]). This study was performed to compare the findings of TR-MRA with conventional angiography for the characterization of endoleaks. METHODS: Between June 2002 and June 2003, 12 patients with documented endoleaks following endovascular repair of aortic aneurysms (10 abdominal and two thoracic) underwent TR-MRA to identify and characterize the endoleak. All patients had nitinol-based aortic stent grafts. MRA was performed on a 1.5-Tesla magnet (Sonata class; Siemens Medical Systems, Iselin, NJ). The TR-MRA studies were reviewed under continuous observation as a "cine MR angiogram." These MRA data sets were used to classify the endoleaks into types 1 through 3. The patients underwent conventional angiography following the MRA to confirm the findings and to plan treatment. The MRA findings were compared with the findings made at conventional arteriography. RESULTS: TR-MRA identified seven patients with type 1 leaks, including four proximal and three distal. Four patients had type 2 leaks, including two arising from the inferior mesenteric artery and two from an iliolumbar artery. One patient had a type 3 leak. Conventional angiography confirmed the type of endoleak in all 12 patients. CONCLUSION: These initial results demonstrate TR-MRA to be an effective noninvasive method for classifying endoleaks. This technique may allow for screening of patients with endoleaks to identify those requiring urgent repair.

Angiography, Digital Subtraction↗

PubMed1999

Diagnosis of pulmonary embolism: comparison of CT angiography and MR angiography in canines.

PURPOSE: To compare the sensitivity and specificity of helical computed tomographic angiography (CTA), CTA with multiplanar reconstructions (MPR)/three-dimensional-shaded surface display (3D-SSD), and gadolinium-enhanced magnetic resonance angiography (MRA) for pulmonary embolism (PE) detection. MATERIALS AND METHODS: Gelatin sponge emboli were introduced into the femoral veins of seven dogs and conventional digital subtraction angiography (CA), CTA, and MRA performed. Images from CTA, CTA with MPR/3D-SSD, and MRA were reviewed for the presence of PE in lobar and segmental arteries, and subsegmental zones. Postmortem angiography and CA were the gold standard. RESULTS: There were 50 emboli in the 294 vessels/zones analyzed. The sensitivity of CTA for the two readers was 76% (95% confidence interval [CI]; 64%-88%) and 64% (95% CI; 50%-78%), and for the two MRA readers was 52% (95% CI; 38%-66%) and 48% (95% CI; 34%-62%). CTA was more sensitive than MRA when PE were subdivided by vessel caliber. Specificity was high for CTA and MRA among all readers (98.8%-99.6%). MPR/3D-SSD did not improve results of axial CT. MRA perfusion defects were 46% and 47% sensitive and 100% specific. Interobserver agreement was high for CTA and MRA (kappa 0.92 and 0.93, respectively). The average diameter of vessels with emboli was 3.7 mm +/- 1.06. CONCLUSION: Helical CTA is more sensitive than three-dimensional gadolinium-enhanced MRA for the detection of PE. Both CTA and MRA are highly specific for PE detection and demonstrate high interobserver agreement. MPR/3D-SSD did not increase CTA performance over axial images alone.

Angiography↗

PubMed2006

A comparison of magnetic resonance angiography with conventional angiography in the diagnosis of tetralogy of Fallot.

AIMS: Our purpose was to assess the value of magnetic resonance angiography as a non-invasive alternative to catheterization in the evaluation of patients with tetralogy of Fallot, including those with pulmonary atresia. METHODS AND RESULTS: We evaluated prospectively, using magnetic resonance angiography, 30 patients, aged from 1 to 18 years, 15 with tetralogy of Fallot and pulmonary stenosis, and 15 with pulmonary atresia. The studies obtained using magnetic resonance provided adequate visualization of the aorta, and provided excellent imaging of the pulmonary trunk and its right and left branches. Compared with catheterization, magnetic resonance had 100 percent sensitivity, specificity and accuracy for defining the presence or absence of the pulmonary arteries. Magnetic resonance also had 93.9 percent sensitivity, 98.2 percent specificity, and 96.7 percent accuracy for detection of stenosis or hypoplasia of the pulmonary arteries. We detected 25 major aortopulmonary collateral arteries with magnetic resonance, but only 22 with conventional angiography. There was complete agreement between the two methods in detecting patency of the arterial duct in 6 patients, and of Blalock-Taussig shunts in 12 patients. CONCLUSION: Magnetic resonance angiography is a useful tool in the evaluation of patients with tetralogy of Fallot. It can be considered a non-invasive alternative to cardiac catheterization in the evaluation of the pulmonary vascular anatomy.

Adolescent↗

PubMed2001

Comparison of spiral CT angiography with conventional digital subtraction angiography in the evaluation of renal transplant donors: a pilot study.

Conventional digital subtraction renal arteriography (IA-DSA) has been traditionally used as the preoperative imaging modality for assessment of renal vascular anatomy for renal transplant donors. This study evaluates the potential use of spiral CT angiography in replacing IA-DSA in the preoperative assessment of this group of patients. Seven patients underwent both spiral CT angiography and IA-DSA between October 1997 and April 1998. It is concluded that spiral CT angiography can demonstrate the number, length and location of renal arteries and it is suggested that spiral CT angiography can potentially replace IA-DSA in the preoperative assessment of renal donors.

Adult↗

PubMed1999

[MR angiography of peripheral vessels with automatic tracking table technique at 1.0 in comparison with intra-arterial digital subtraction angiography].

PURPOSE: Contrast-enhanced (CE) 3D-MR angiography of peripheral arteries was performed in 8 patients with peripheral arterial occlusive disease by applying a new tracking technique on a 1.0 T system (Magnetom Harmony, Siemens). The studies were compared with intra-arterial digital angiography as gold standard. MATERIALS AND METHODS: Imaging of the distal aorta, pelvis, upper and lower limb arteries was accomplished with a Flash-3D-sequence (TR/TE = 6.2/3.2 ms) within 26 s acquisition time of each region after a single bolus of 30 ml contrast agent. Individual circulation time was determined by a test bolus before each examination. RESULTS: 112 vessel segments were evaluated. MR angiography achieved a sensitivity of 89% and a specificity of 100% for detecting high grade stenoses and vessel occlusions. CONCLUSIONS: Tracking CE 3D-MR angiography with a 1.0 T MR imager proved to be a promising method in evaluating hemodynamically significant stenoses and occlusions of peripheral arteries. However, its definite role in the diagnostic work-up of peripheral arterial occlusive disease has to be evaluated in larger prospective studies.

Angiography, Digital Subtraction↗

PubMed2003

Three-dimensional respiratory-gated coronary MR angiography with reference to X-ray coronary angiography.

PURPOSE: To assess the clinical value of three-dimensional coronary MR angiography (CMRA) in the detection of significant coronary artery stenosis using conventional X-ray angiography as the standard reference. MATERIAL AND METHODS: Sixty-nine patients underwent X-ray coronary angiography and CMRA because of suspected or previously diagnosed coronary artery disease. MRI was performed with a 1.5-T whole body imaging system using ECG-triggered 3D gradient echo sequence with retrospective navigator echo respiratory gating and fat suppression. RESULTS: A total of 276 coronary artery segments were analyzed. The X-ray coronary angiography was normal in 22 patients. Significant proximal stenoses (exceeding 50%) or occlusions were present in 102 coronary artery segments. In all, 120 stenoses or occlusions were identified in CMRA. Sixteen percent of the coronary artery segments had to be excluded because of poor image quality. The overall sensitivity and specificity for MRA for identification of significant stenosis were 75% and 62%, respectively. CMRA correctly detected 89% of patients with at least one vessel disease, but 6 patients with coronary artery disease would have been missed. CONCLUSIONS: Because of the high data exclusion and false- negative case rate, CMRA with retrospective navigator echo triggering is at present not suitable as a clinical screening method in coronary artery disease.

Adult↗

PubMed2004

Correlation between magnetic resonance angiography (MRA) and quantitative coronary angiography (QCA) in ectatic coronary vessels.

Coronary artery ectasia (CAE) is defined as a dilatation of an arterial segment to a diameter at least 1.5 times that of the adjacent normal artery. The correct follow-up of ectatic vessels is hampered by the need for repeat angiograms. In this work we compared quantitative coronary angiography (QCA) measurements of the diameter of the proximal most ectatic part of coronary vessels, with corresponding measurements obtained by magnetic resonance angiography (MRA) using both gradient echo and turbo spin echo imaging sequences. Fifteen patients (14 male), aged 45-65 years, with known CAE were prospectively studied. Two electrocardiogram (ECG)-triggered pulse sequences were implemented for coronary magnetic resonance angiography. The first was a three-dimensional (3D), segmented, k-space gradient-echo sequence, employing a T2-weighted preparation prepulse and a frequency-selective, fat-saturation prepulse to enhance "white blood" (WB) contrast of the coronary arteries. The second sequence was an M2D dual Inversion Recovery (IR) Turbo Spin-Echo with a linear k-space acquisition scheme, providing "black-blood" (BB) contrast of the coronaries. All scans were carried out with the patient free breathing using a 2D, real-time Navigator beam, for respiratory motion tracking and gating. All patients underwent QCA, and the diameter of the proximal most ectatic part of each vessel was measured and compared with "white-blood" and "black-blood" MRA measurements. The average length of continuously visualized LM, LAD, LCx, and RCA by MRA was 2.5 +/- 0.3, 5.8 +/- 0.8, 3.9 +/- 1.0, and 7.2 +/- 1.2 cm, respectively. There were no statistically significant differences between diameter measurements of the proximal most ectatic part of each vessel, obtained with WB and BB sequences. There was a close correlation between MRA and QCA measurements (r = 0.87, p < 0.001). Bland-Altman analysis showed no systematic differences between the examined methods, over the whole range of vessel diameters measured. Coronary MRA is in close correlation with QCA for CAE detection. Magnetic resonance angiography, being noninvasive, may prove of significant value for the efficient follow-up of these patients.

Aged↗

PubMed2005

Stenosis detection with MR angiography and digital subtraction angiography in dysfunctional hemodialysis access fistulas and grafts.

PURPOSE: To prospectively assess three-dimensional contrast material-enhanced magnetic resonance (MR) angiography for stenosis depiction in malfunctioning hemodialysis arteriovenous fistulas (AVFs) and grafts (AVGs), as compared with digital subtraction angiography (DSA). MATERIALS AND METHODS: Ethical review board approval and written informed consent were obtained. MR angiography and DSA were performed in 51 dysfunctional hemodialysis fistulas and grafts in 48 consecutive patients. Vascular tree of accesses was divided into between three and eight segments depending on access type (AVF or AVG) and length of venous outflow. Images obtained with MR and DSA were interpreted by two MR radiologists and two interventional radiologists, respectively, who were blinded to information from each other and other studies. DSA was reference standard for stenosis detection. Sensitivity, specificity, and predictive values with 95% confidence intervals (CIs) of contrast-enhanced MR in detection of vascular segments containing hemodynamically significant (> or =50%) stenosis were calculated. Linear-weighted kappa statistic was calculated for contrast-enhanced MR and DSA to determine interobserver agreement regarding stenosis detection. RESULTS: A total of 282 vascular segments were evaluated. Contrast-enhanced MR depicted three false-positive stenoses and all but two of 70 significant stenoses depicted with DSA. Sensitivity, specificity, and positive and negative predictive values of MR in detection of vessel segments with significant stenoses were 97% (95% CI: 90%, 99%), 99% (95% CI: 96%, 100%), 96% (95% CI: 88%, 99%), and 99% (95% CI: 97%, 100%), respectively. MR demonstrated significant stenosis in four of five nondiagnostic DSA segments, whereas DSA showed no significant stenosis in four nondiagnostic MR segments. Linear-weighted kappa statistic for interobserver agreement regarding stenosis detection was 0.92 (95% CI: 0.89, 0.95) for MR and 0.95 (95% CI: 0.92, 0.97) for DSA. CONCLUSION: MR angiography depicts stenoses in dysfunctional hemodialysis accesses but has limited clinical value as result of current inability to perform MR-guided access interventions after stenosis detection. MR of dysfunctional access should be considered only if nondiagnostic vascular segment is present at DSA.

Adult↗

PubMed1993

Femoral MR angiography versus conventional angiography: preliminary results.

PURPOSE: To develop a bilateral femoral magnetic resonance (MR) angiographic examination that would include the aortic bifurcation to the ankle. MATERIALS AND METHODS: Thirty-seven patients underwent conventional angiography and the bilateral femoral MR angiographic examination. Two-dimensional time-of-flight angiography was used for all studies. RESULTS: The femoral MR angiogram could have replaced the conventional angiogram in 57% of patients (21 of 37). In 43% of patients (16 of 37), the femoral MR angiogram could not have replaced the conventional angiogram. Reasons for diagnostic failure with femoral MR angiography included artifact from vascular clips (n = 8) or prosthetic joints (n = 3), overlooked distal aortic stenosis (n = 1), and suboptimal definition of vessels (usually trifurcation vessels) owing to various causes (n = 8). Seven of the patients in this group had bypass grafts. CONCLUSION: Some of the current limitations of femoral MR angiography could be avoided by supplemental duplex sonography around prostheses and vascular clips. The other limitations will require advances in MR imaging techniques.

Aged↗

PubMed1995

Intracranial arteriovenous malformations: quantitative analysis of magnitude contrast MR angiography versus gradient-echo MR imaging versus conventional angiography.

PURPOSE: To quantitatively analyze magnitude contrast (MC) magnetic resonance (MR) angiography and gradient-echo (GRE) MR imaging for evaluation of persistent transnidal blood flow in intracranial arteriovenous malformations (AVMs) of various sizes before or after stereotaxic radiosurgery. MATERIALS AND METHODS: Thirty-three patients with AVMs underwent 42 MC MR angiographic (maximum intensity projection [MIP] and source imaging), GRE imaging with and without flow compensation, and conventional angiographic studies within 90 days of each other. RESULTS: For MIP, source, and GRE images, the sensitivities for detection of large AVMs (> 1 cm) were 95%, 100%, and 100%, respectively, and for small AVMs (< or = 1 cm) were 27%, 50%, and 67%, respectively. MC MR angiography and GRE imaging depicted all eight nidi that were completely thrombosed on conventional angiograms. CONCLUSION: GRE imaging and MC MR angiography reliably depict AVMs larger than 1 cm. GRE is more sensitive for detection of small residual nidi (< 1 cm). Source images must be evaluated to accurately assess low-flow lesions. Neither GRE nor MR angiography is reliable for detection of mean nidus diameters less than 0.36 cm.

Cerebral Angiography↗

PubMed2000

Three-dimensional, navigator-echo MR coronary angiography in detecting stenoses of the major epicardial vessels, with conventional coronary angiography as the standard of reference.

PURPOSE: To test three-dimensional (3D), navigator-echo magnetic resonance (MR) coronary angiography in detecting stenoses of the coronary arteries. MATERIALS AND METHODS: Forty-two patients (age range, 50-79 years) underwent MR coronary angiography (1.5 T). A navigator-echo sequence was used. Two or three 15% overlapped transverse slabs were acquired. Data were analyzed by readers blinded to conventional coronary angiographic results. On conventional coronary angiograms, coronary arterial stenoses of 50% or greater narrowing were considered significant. On MR coronary angiograms, the major coronary vessels were subdivided into proximal (within 5 cm) and distal (beyond 5 cm) segments, except for the left main vessel. Stenoses of 50% or greater were identified on reformatted multiplanar MR coronary angiograms. RESULTS: Three MR coronary angiographic examinations were aborted because of patient claustrophobia; 39 of 39 left main, 117 of 117 proximal, and 78 of 117 distal segments were visualized. MR coronary angiography showed a sensitivity of 82% (95% CI: 73%, 91%) and a specificity of 89% (95% CI: 85%, 94%) in overall stenoses identification, of 90% (95% CI: 81%, 99%) and 90% (95% CI: 83%, 96%) for proximal segments, and of 68% (95% CI: 50%, 86%) and 81% (95% CI: 71%, 92%) for distal segments, respectively. CONCLUSION: Navigator-echo, 3D MR coronary angiography is a promising sequence for assessing coronary arterial stenoses, but further improvements are required for distal segments.

Aged↗

PubMed2001

[Magnetic resonance angiography of intracranial aneurysms: comparative study with cerebral angiography].

We studied by magnetic resonance angiography and cerebral angiography 41 patients with 55 aneurysms confirmed by surgery. The MR angio detected 52 aneurysms with sensibility of 94.5% and the cerebral angiography detected 53 aneurysms with sensibility of 96.3%. For being non invasive, more quickly and less expensive MR angio may substitute vascular angiography in the diagnosis of intracranial aneurysms and prognosis of the subarachnoid hemorrhage

Adult↗

PubMed2004

Three-dimensional digital angiography: new tool for simultaneous three-dimensional rendering of vascular and osseous information during rotational angiography.

Three-dimensional (3D) digital subtraction angiography (DSA) is the latest development in the neurovascular imaging armamentarium. 3D-DSA combines the anatomic resolution of DSA with 3D visualization abilities previously offered by only CT or MR angiography. 3D-DSA provides more detailed information than does DSA alone in the evaluation of neurovascular lesions, such as cerebral aneurysms. However, the inability of 3D-DSA to simultaneously image osseous and vascular structures is noted as a weakness of this technique compared with CT angiography. We describe a new 3D digital angiography reconstruction algorithm that allows the concurrent display of the cerebral vasculature and the osseous landmarks.

Adult↗

PubMed1995

[The evaluation of 3DFT time-of-flight MR-angiography versus angiography in the study of carotid atheromatous lesions with a review of the literature].

In 37 patients suspected of having a stroke 71 carotid bifurcations were explored by MR-angiography and by digital angiography the reference technique. A 3D sequence was acquired with the time-of-flight technique, using a transmitter-receiver cranial coil, followed by a strictly receiver Helmoltz coil on a 1 Tesla magnet. Two examiners evaluated the carotid bifurcations and measured the degree of stenosis in terms of diameters, according to the north american symptomatic carotid endarterectomy trial (NASCET). Five classes were established: class 1: normal; class 2: 1 to 29%; class 3: 30 to 69%; class 4: 70 to 99% and class 5: thrombosis. The results obtained in the determination of classes were identical with both coils: the coefficient of correlation with straight angiography were 0.973 with the cranial coil and 0.966 with the Helmoltz coil. Five stenoses were overestimated and classified as Class 3 instead of Class 2. The five stenoses greater than 70% (Class 4) showed a signal-void area at their level, due to severe dephasing induced by turbulences. Finally, there was a false-negative image of occlusion: the high-intensity signal of the thrombus was mistaken for one of flow. The data of our study were in accordance with the excellent results obtained by several authors in the literature, which makes it possible for us to propose this type of examination as a novel mean of investigating bifurcations of carotid arteries. Provided a strict technique is applied, and in addition to carotid bifurcation the Willis' circle and the cerebral parenchyma are explored, MR-angiography can complete the results of Doppler-echo. Standard arteriography could then be reserved to surgical patients and to those with discordant results of MR-arteriography and Doppler echo systems.

Angiography, Digital Subtraction↗

PubMed1997

Comparison of two-dimensional time-of-flight dynamic magnetic resonance angiography with digital subtraction angiography in popliteal artery entrapment syndrome.

OBJECTIVE: To assess dynamic magnetic resonance angiography (MRA) as an alternative to catheter angiography in patients with popliteal artery entrapment syndrome (PAES). PATIENTS AND METHODS: Nine patients with surgically proven PAES underwent provocation digital subtraction angiography (DSA) and 2-dimensional time-of-flight dynamic MRA of the popliteal fossae (total of 17 limbs). Eight normal volunteers also underwent dynamic MRA (total of 16 limbs). Two observers blinded to the surgical findings and the results of DSA independently evaluated the 33 limbs of the 17 subjects on the basis of maximum-intensity projection images and transverse MRA source images. The degree of stenosis was graded and compared with that indicated by DSA. RESULTS: Among the 17 limbs of patients with surgically proven PAES, dynamic MRA suggested the correct diagnosis in 13 (76%) by indicating stenosis greater than 50%. Dynamic MRA indicated stenosis of 1% to 50% for 4 (25%) of the 16 normal limbs and no stenosis in the other 12 normal limbs (i.e., no false positive results). CONCLUSION: Catheter angiography is not necessary if dynamic MRA indicates stenosis of greater than 50% in patients with clinical suspicion of PAES, but is recommended if dynamic MRA indicates stenosis of 1% to 50%.

Adolescent↗