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At least 235 records · Page 13Linked to original sources
PubMed1997

Fluorescein angiographic evaluation of the effect of latanoprost treatment on blood-retinal barrier integrity: a review of studies conducted on pseudophakic glaucoma patients and on phakic and aphakic monkeys.

Endogenous prostaglandins (PGs) have been claimed to play a role in the development of cystoid macular edema (CME). Two fluorescein angiographic studies evaluating the effect of latanoprost, a new ocular hypotensive PG analogue, on blood-retinal barrier integrity are, therefore, reviewed here. In the first study, six of eight unilaterally aphakic cynomolgus monkeys were treated bilaterally once daily for six months with 0.035% latanoprost (seven times the clinically used oculohypotensive concentration). Two of the animals served as controls. Fluorescein angiography of the fundus after one, three and six months of treatment revealed no leakage of fluorescein in any of the 16 eyes. In another study, pseudophakic eyes of 16 glaucoma patients who received twice-daily treatment with 0.006% latanoprost for four weeks were compared to eight patients treated with placebo. Biomicroscopic examination did not reveal any signs of CME and only one placebo-treated eye revealed a slight perifoveal leakage of fluorescein. These studies suggest that topically-applied latanoprost does not have a fluorescein angiographically detectable direct effect on the integrity of the blood-retinal barrier system in phakic or aphakic monkey eyes or in pseudophakic human eyes. This does not rule out the occurrence of CME in eyes more susceptible to CME, due to vitreous loss, posterior capsulotomy, or other postoperative situations. Especially in those eyes a study with latanoprost is proposed. Since, fluorescein angiography is a rather crude method of detecting abnormalities of the blood-retinal barriers, vitreous fluorometry in addition is suggested.

Animals↗
PubMed1978

Secondary lens implantation in aphakia: visual results and complications.

We reviewed 70 cases that had undergone secondary lens implantation. The lenses used included 34 Medallion and 36 Choyce Mark VIII lenses. A 20/40 or better vision was present in 74.3% of the cases before implantation, and could be achieved postoperatively in 95.7% of the cases. Corneal changes, i.e. endothelial corneal dystrophy and induced astigmatism, were not noted in cases where Choyce Mark VIII lenses were used. Cystoid macular edema occurred in three cases where surgery followed an intracapsular cataract extraction (5.3%).

Adult↗
PubMed1979

Iseikonic lens implantation in anisometropia.

The implantation of an iseikonic prepupillary intraocular lens in unilateral aphakia usually requires a slight (2 D) myopia of the implanted eye if the two eyes are isometropic. On the other hand, the implantation of an iseikonic implant in one eye of a anisometropic (asymmetric) eye pair can result in unexpectedly high changes in spectacle ametropia, due to differences in axial length or corneal power. The changes in ametropia after iseikonic lens implantation are discussed in relation to preoperative corneal and axial anisometropias. Alternative procedures to iseikonic implantation are described.

Aniseikonia↗
PubMed1980

Prolonged wear soft contact lenses.

Of 78 patients eligible for prolonged wear contact lenses, 50 (65%) were successfully fitted and followed for four months to four years. The most serious complication was peripheral corneal ulceration, occurring in 5 (10%) patients. None of these patients suffered permanent visual loss. The fitting of prolonged wear lenses required six or seven office visits during the first year and at least one lens per eye during the first year, for uncomplicated cases. In difficult cases the number of office visits and the number of replacement lenses increased significantly. In terms of the number of office visits and replacement lenses, the soft contact lens compares unfavorably with the intraocular lens. It is our feeling that the prolonged wear soft contact lens should be used when a lens implant is contraindicated or as an alternative to secondary lens implantation.

Aphakia, Postcataract↗
PubMed1980

Qualitative photostress testing for the diagnosis of cystoid macular edema.

The qualitative photostress test is a simple kinetic test for the evaluation of macular function. The physiological basis of the test is discussed and the results of testing 20 normal patients and 14 postoperative cataract patients are presented. Patients with CME have a severe functional defect that is readily demonstrated with photostress testing.

Adult↗
PubMed1981

Management of glaucoma in the implanted patient.

Implanting an intraocular lens in an eye with controlled open angle glaucoma or angle closure glaucoma does not adversely affect the eye's status. Furthermore, it is extremely rare for primary glaucoma to develop in an eye postimplantation. Secondary glaucoma is certainly more common, although its incidence is not substantially greater than that in nonimplanted eyes. Special considerations with respect to medical therapy and surgical treatment of secondary glaucoma in pseudophakia are discussed.

Aphakia, Postcataract↗
PubMed1981

The effects of a penetrating metallic foreign body on a pseudophakic eye.

The penetration of a pseudophakic eye by a high-speed metallic foreign body is reported. The path of the steel missile was interrupted by the intraocular lens, which was fixed within the capsular remnant, preventing missile penetration into the posterior segment. Although the foreign body was removed from the anterior chamber without immediate sequelae, several months later a peripheral retinal detachment occurred. Prompt recognition and treatment resulted in the retention of excellent pseudophakic vision. The importance of postoperative protective eyewear is emphasized.

Aged↗
PubMed1981

Aniseikonia in patients with a unilateral artificial lens, measured with Aulhorn's phase difference haploscope.

Aniseikonia was measured in unilaterally pseudophakic patients using Aulhorn's phase difference haploscope. Mean values of aniseikonia were 1.5% horizontally and 2.0% vertically without correction, and 2.1% horizontally and 2.3% vertically with correction. With spectacle correction, the greater the dioptric difference between two eyes, the greater the amount of aniseikonia. In either case, patients tolerated these amounts of aniseikonia according to our criteria of aniseikonia tolerance.

Aged↗
PubMed1982

Secondary and exchange posterior chamber lens implantation.

A retrospective chart review of 34 secondary or exchange posterior chamber lens implantations was performed. Overall 94% of the patients achieved a visual acuity of 20/40 or better at six to 12 months postoperative. Associated intraoperative procedures included lens implant removal for exchange (50%), iris suture (41%), posterior capsule polishing (24%) or discussion (24%), and anterior vitrectomy (15%). The postoperative complications included retinal detachment (6%), persistent clinical cystoid macular edema (3%), posterior capsular opacification (3%), failure to fixate requiring iris suture (3%), hyphema (3%), and pupil capture (3%). Secondary and exchange posterior chamber lens implantation can be performed with satisfactory visual acuity results but there is a real rate of complication that needs to be considered by the surgeon and patient who is contemplating the operation.

Adult↗
PubMed1982

Assessment of intraocular lens implantation in children.

Visual rehabilitation by conventional aphakic spectacles and contact lenses has posed a serious problem in the pediatric population. While the use of intraocular lenses has not achieved widespread acceptance as a form of aphakic correction, we have obtained encouraging results in some of our patients. In this report, we discuss two categories: those patients with congenital cataracts, and those patients with traumatic cataracts.

Age Factors↗
PubMed1983

Unilateral pseudophakia and extended-wear aphakic contact lenses. A comparative study in a single patient population.

Twenty-nine patients who were pseudophakic in one eye and wearing a Permalens in the other eye were evaluated. Pseudophakic correction provided the patient with good, stable visual acuity, minimal risks, and an excellent long-term prognosis. Permalens aphakic correction also provided the patient with good, but fluctuating visual acuity. Risks such as deposit formation, tight lens syndrome, and corneal infections were not infrequently associated with the Permalens, and Permalens patients were also faced with the recurring cost of lens replacement. While both modalities of aphakic visual rehabilitation are acceptable, pseudophakia appears to provide the patient with better visual acuity, fewer risks, and lower financial costs in the long run.

Aged↗
PubMed1983

Ultraviolet-absorbing pseudophakos: an efficacy study.

The use of intraocular lenses (IOLs) to replace cataractous lenses has raised question of possible retinal damage due to exposure to ultraviolet (UV) radiation. Three groups of cynomolgus monkeys underwent cataract operations and either received normal UV-transparent IOLS or UV-opaque IOLs, or were left aphakic. All eyes were later exposed to UV light for varying periods of time. Exposure to UV light produced severe retinal lesions. In aphakic eyes and those with normal IOLs lengthy exposure to low levels of UV light produced lesions similar to those seen after brief, very intense UV radiation. Eyes with UV-opaque IOLs displayed no such lesions. Our results indicate that clinicians should consider the use of UV-opaque IOLs.

Animals↗
PubMed1983

Secondary implantation of anterior chamber lenses.

One hundred and sixty-nine aphakic eyes underwent secondary implantation of anterior chamber lenses. The postoperative visual acuity decreased by one or more lines in five eyes (3%), remained the same in 71 eyes (42%), and improved by one or more lines in 93 eyes (55%). The presence of macular degeneration, background diabetic retinopathy, and open-angle glaucoma with a cup-to-disc ratio of 0.6 or less did not contribute to any visual deterioration.

Anterior Chamber↗
PubMed1984

Aqueous humor cytology of pseudophakic bullous keratopathy.

The long-term effects of the interaction between an IOL and the immune system of the implanted patient are not yet clear. This study presents the results of aqueous humor (AH) cytological analysis of 51 patients undergoing intraocular surgery for cataract, and aphakic (ABK) or pseudophakic bullous keratopathy (PBK). Cataract AH was acellular (N = 8). The mean ABK AH cell count was 8.5 +/- 6.4 cells per high power field (hpf) of cytologically filtered specimens; mean PBK cell count was 30.2 +/- 13.0. If inflamed eyes are defined as those with more than one cell/hpf, a statistically significant greater number of PBK eyes than ABK eyes were inflamed (93% versus 44%, P less than 0.003 chi square). More than 99% of the nucleated cells were mononuclear histiocytes. One PBK patient had many multinucleated giant cells in the AH.

Aphakia, Postcataract↗