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Retinal location and its effect on the processing of target and distractor information.

Two experiments were conducted to study the perceptual facilitation and inhibition that occurs between foveal and parafoveal or peripheral regions of the eye. Experiment 1 used a Stroop task to compare color detection latencies of foveal and parafoveal targets. The target and distractor components of the Stroop stimuli were separated and presented with varied stimulus onset asynchronies. Experiment 2 used a Stroop-like task to replicate and extend the findings into the visual periphery. Subjects were found to process foveally presented distractor information while attending to targets presented in parafoveal or peripheral regions of the eye. Distractor information that was incompatible was suppressed while compatible information was used to facilitate target processing. When the targets were presented foveally along with the distractor information, subjects appeared to automatically process the distractor information. The findings are discussed within the framework of past studies that presented subjects with competing tasks across retinal location. The implications of these findings to a two-process theory of attention are also considered.

Attention↗

Markovian domain fingerprinting: statistical segmentation of protein sequences.

MOTIVATION: Characterization of a protein family by its distinct sequence domains is crucial for functional annotation and correct classification of newly discovered proteins. Conventional Multiple Sequence Alignment (MSA) based methods find difficulties when faced with heterogeneous groups of proteins. However, even many families of proteins that do share a common domain contain instances of several other domains, without any common underlying linear ordering. Ignoring this modularity may lead to poor or even false classification results. An automated method that can analyze a group of proteins into the sequence domains it contains is therefore highly desirable. RESULTS: We apply a novel method to the problem of protein domain detection. The method takes as input an unaligned group of protein sequences. It segments them and clusters the segments into groups sharing the same underlying statistics. A Variable Memory Markov (VMM) model is built using a Prediction Suffix Tree (PST) data structure for each group of segments. Refinement is achieved by letting the PSTs compete over the segments, and a deterministic annealing framework infers the number of underlying PST models while avoiding many inferior solutions. We show that regions of similar statistics correlate well with protein sequence domains, by matching a unique signature to each domain. This is done in a fully automated manner, and does not require or attempt an MSA. Several representative cases are analyzed. We identify a protein fusion event, refine an HMM superfamily classification into the underlying families the HMM cannot separate, and detect all 12 instances of a short domain in a group of 396 sequences. CONTACT: jill@cs.huji.ac.il; tishby@cs.huji.ac.il.

Algorithms↗

Making the fit: orienting new employees to community health nursing agencies.

Community health nurse managers require tested orientation methods to fit new employees into the rapidly changing conditions of professional practice, increase nursing productivity, and reduce turnover. The clinical competencies for community health nursing provide a workable framework for applying orientation principles to the special demands of community health nursing.

Community Health Nursing↗

Encephalization, adaptation and evolution of chiroptera: A statistical analysis with further evidence for bat monophyly.

As part of a large-scale study on brain morphometrics and adaptations in mammals, we addressed the problem of chiropteran evolution. A specific statistical framework was designed to test which of two competing hypotheses (bat monophyly vs. diphyly) is more strongly supported by quantitative brain data. Our analyses, based on 120 species, revealed that megabats and microbats were more closely related to each other than to primates, and illustrated the convergent adaptations of the brain of bats to similar trophic (i.e. feeding related) niches. Ecologically-corrected characters were then used to derive a new phylogeny which also supports the chiropteran clade. The monophyletic origin of bats is the preferred hypothesis to explain brain quantitative evolution in chiropterans and primates.

Adaptation, Physiological↗

Individual and community: normative conflicts in the development of a new therapeutic community for older persons.

This paper examines the role of ideology in the establishment of a new therapeutic community for geriatric patients in a state mental hospital. Contradictory role expectations, reflected both in staff-staff and in staff-patient relationship, interfered with the program's achieving its stated goals. In order to apply a humanistic approach to programs for elderly patients, realistic goals-encompassing the range of patient competence-must be set within a reasonable time framework, and the program must provide for an appropriate range of structure.

Aged↗

Recent trends in the demography of heroin addiction among youthful offenders.

Trends in demographic characteristics associated with heroin addiction in successive cohorts of a young offender population over the 5-year period 1968-1972 were examined within the framework of two contradictory views of the social competence of the addict provided by the literature. In general, heroin addicts during this period were found to be older, better educated, and more intelligent than nonaddicts. In addition, the racial composition of both the addict and nonaddict samples became increasingly non-White in composition and better educated; nonaddicts became increasingly older; and no significant trends with respect to intelligence took place. These findings support the view of the addict as being relatively more socially competent than his nonaddict offender peer. Implications of these findings for a model of addiction and rehabilitation are discussed.

Achievement↗

Ranking radiotherapy treatment plans using decision-analytic and heuristic techniques.

Radiotherapy treatment optimization is done by generating a set of tentative treatment plans, evaluating them and selecting the plan closest to achieving a set of conflicting treatment objectives. The evaluation of potential plans involves making tradeoffs among competing possible outcomes. Multiattribute decision theory provides a framework for specifying such tradeoffs and using them to select optimal actions. Using these concepts, we have developed a plan-ranking model which ranks a set of tentative treatment plans from best to worst. Heuristics are used to refine this model so that it reflects the clinical condition of the patient being treated and the practice preferences of the physician prescribing the treatment. A figure of merit is computed for each tentative plan, and is used to rank the plans. The approach described is very general and can be used for other medical domains having similar characteristics. The figure of merit can also be used as an objective function by computer programs that attempt to automatically generate an optimal treatment plan.

Artificial Intelligence↗

Judicial postponement of death recognition: the tragic case of Mary O'Connor.

A recent New York Court of Appeals decision seriously impedes the ability of incompetent patients to control their medical care. In the case of Mary O'Connor, the court virtually eliminated an incompetent's rights to bodily integrity and privacy. The court relied on formalistic evidentiary arguments to vitiate the patient's refusal of death-prolonging treatment. This Case Comment examines both the doctrine and policy underlying the O'Connor decision, suggesting that the court erred in its holding and reasoning. An alternative framework is presented, arguing that courts should honor competently expressed patient decisions concerning medical treatment. New York's highest court, instead, posited an incompetent patient who becomes competent for a moment to render a decision. This legal fiction is nothing more than a thinly masked technique for imposition of the judges' values on the patient. This Case Comment argues that in the absence of clear direction from the patient, family and loved ones generally should make care decisions for the patient.

Aged↗

Developing and negotiating transfer agreements in allied health.

The Kentucky Council on Higher Education has developed a statewide articulated system for allied health education. The articulated system permits entry and exit of prepared professionals at a variety of levels. The six disciplinary clusters included in the system are clinical laboratory sciences, dental auxiliaries, dietetics/nutrition, rehabilitation therapies, radiological sciences, and respiratory therapy. Competency-based education was used as the theoretical framework for developing and negotiating transfer agreements. Types of agreements included the block credit transfer agreement and the course specific transfer agreement. Agreements were negotiated between education systems and between specific programs/institutions. To date, approximately 30 transfer agreements have been negotiated. The process for negotiating transfer agreements included the following sequence: identify programs, develop a theoretical articulation model, rank order transfer agreements, determine the type of agreement, review respective curricula, determine the existing amount of transferable coursework, draft a pre-articulation agreement, schedule a meeting between faculty and administrators to discuss the agreement, and secure authorizing signatures on the final transfer agreement. Facilitators and barriers to negotiating agreements are discussed and recommendations offered for others who may be interested in developing transfer agreements.

Allied Health Personnel↗

Collaborative teaching--learning: a potential framework for staff development educators.

The nursing staff development educator is challenged constantly to use adult education principles when planning programs and evaluating outcomes. The educator, however, may lack a formal theoretical framework to accomplish this goal. In this study, the author suggests that the principles of collaborative teaching-learning may serve as a framework to promote both program development and staff competency within the hospital setting.

Adult↗

Analytical goals in therapeutic drug monitoring.

The practice of therapeutic drug monitoring is based on several disciplines, including pharmacokinetics, pharmacodynamics, and chemical analysis. The impact of the analysis on the determination of pharmacokinetic parameters is not well appreciated. Analytical goals in therapeutic drug monitoring should be established by determining the nature of the problem to be solved, selecting the appropriate matrix and methodology to solve the problem, and developing valid analytical schemes that are performed competently with appropriate quality and interpreted within the framework of the problem.

Blood Chemical Analysis↗

A model for implementing the "Scope of Professional Practice".

Safe and effective administration of intravenous therapy to children is essential. The training, education and assessment (TEA) programme aimed to integrate the essence of the Scope of Professional Practice with a competency based approach to teaching and assessing essential skills. The TEA programme was developed to reflect the Scope of Professional Practice, individual accountability, and current best evidence. A significant part of the programme is the development of an innovative assessment document providing individuals with documented evidence of related knowledge and skills which can form part of their Professional Portfolio. The TEA programme has been implemented within the trust in line with trust clinical governance strategy. The framework for implementing this programme has also been used for developing TEA for other expanded roles within the trust. Further comprehensive evaluation of the programme through areas such as audit of practice and clinical incidence analysis is needed. Further research to broaden the evidence base for practice is also needed. These will be initiated through established clinical governance frameworks.

Clinical Competence↗

The 1999 Eleanor Clarke Slagle Lecture. Defining lives: occupation as identity: an essay on competence, coherence, and the creation of meaning.

This article presents a view of occupation as the principal means through which people develop and express their personal identities. Based on a review of theory and research, it proposes that identity is instrumental to social life because it provides a context for deriving meaning from daily experiences and interpreting lives over time. The article proposes that identity also provides a framework for goal-setting and motivation. It is asserted that competence in the performance of tasks and occupations contributes to identity-shaping and that the realization of an acceptable identity contributes to coherence and well-being. Within this framework, it is postulated that performance limitations and disfigurement that sometimes result from illness or injury have identity implications that should be recognized by occupational therapy practitioners. By virtue of their expertise in daily living skills, occupational therapy practitioners are well positioned to help address the identity challenges of those whom they serve. In so doing, they make an important contribution to meaning and well-being.

Humans↗

An alternative baccalaureate curriculum plan for RNs.

It is a need of our times to improve the quality of baccalaureate programs for RN students. Professional pressures to secure the degree must be accompanied by the availability of appropriate programs. The yardstick of measure should not differ between generic or RN student. Care should be taken to assure that the competencies commensurate with a baccalaureate degree are attained by any graduate. It is inappropriate to extend the learning requirements for RNs beyond the basic degree requirements. In developing an alternative program for RNs, care should be taken to provide a program congruent with the philosophy, conceptual framework and objectives of the parallel program. Since the entering competencies of RNs differ from those of the basic student, curricular alternatives and course modification should address only that portion of knowledge that is unique. Clinical experiences should be planned to facilitate skill development in those areas that are needed. Registered nurse students should not be placed in clinical sections which fail to foster new skill development. Hopefully, as schools develop more appropriate BS(N) educational programs we will enjoy the success of assisting in the learning process and find the graduates not merely pleased by the degree obtained as a route to better employment opportunities but pleased with the knowledge and skills they have obtained by way of the degree.

Competency-Based Education↗

Preparedness on the frontline: what's law got to do with it?

The article provides an overview of current work toward identifying core competencies for public health emergency and bio-terrorism response, including law-related competencies. It demonstrates how competency sets are interrelated and how they provide a framework for developing preparedness training for public health leaders, public health and health care professionals, law enforcement, public health attorneys, and others. The health and safety of America's communities hinge on the nation's public health workforce--the estimated 448,254 public health professionals and 3 million related workforce professionals who form the expanded public health system that protects us during times of national crisis and in our daily lives. The response capacity of our health agencies and communities and their ability to respond effectively will be unpredictable without adequate training. Education in the core competencies in emergency preparedness and bio-terrorism response is essential. Preparedness at the front-line means that public health leaders and administrators must be able to communicate information, roles, capacities, and legal authorities to all emergency response partners during planning, drills, and actual emergencies. Each public health worker must be able to describe his or her communication role in emergency response within the agency, with the media, and with the general public. Law enforcement and state government representatives must understand the legal powers of their agencies and of public health agencies for coordinated response, mitigation, and recovery efforts in a public health emergency event.

Biological Warfare↗

Promotion of social change: a conceptual framework.

This paper argues for the need to advance promotion efforts and proposes a conceptual framework for promotion of social change. A brief review is presented of traditional frameworks for the prevention of mental and social disorders and the promotion of wellness and social competencies, with attention to the ways in which promotion of social change extends and departs from these frameworks. In a framework for promoting social change, we advocate for promoting dynamic processes within systems, rather than outcomes within individuals. Systems are viewed as flexible and capable of facilitating multiple adaptive pathways for individuals and groups. Promoting social change also involves careful attention to critical analysis, values, language, and contextual processes. Examples are discussed throughout to illustrate how these principles have been used in the past and can be implemented in future efforts to promote social change.

Health Planning↗

A framework for developing excellence as a clinical educator.

The current emphasis on providing quality undergraduate and postgraduate medical education has focused attention on the educational responsibilities of all doctors. There is a greater awareness of the need to train doctors as educators and courses have been set up to satisfy this need. Some courses, such as those on how to conduct appraisal, are specific to one task facing a medical educator. Other courses take a broader view and relate educational theory to practice. In this paper we describe an outcome-based approach in which competence in teaching is defined in terms of 12 learning outcomes. The framework provides a holistic approach to the roles of the teacher and supports the professionalism of teaching. Such a framework provides the basis for the development of a curriculum for teaching excellence. It helps to define important competences for different categories of teachers, communicate the areas to be addressed in a course, identify gaps in course provision, evaluate courses, assist in staff planning and allow individuals to assess their personal learning needs. The framework is presented to encourage wider debate.

Curriculum↗

Partnership for front-line success: a call for a national action agenda on workforce development.

Despite more than a decade of dialogue on the critical needs and challenges in public health workforce development, progress remains slow in implementing recommended actions. A life-long learning system for public health remains elusive. The Centers for Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry in collaboration with other partners in federal, state, local agencies, associations and academia is preparing a national action agenda to address front-line preparedness. Four areas of convergence have emerged regarding: (1) the use of basic and crosscutting public health competencies to develop practice-focused curricula; (2) a framework for certification and credentialing; (3) the need to establish a strong science base for workforce issues; and (4) the acceleration of the use of technology-supported learning in public health.

Centers for Disease Control and Prevention, U.S.↗