Rhode Island's patient-friendly computer system. This hospital's foodservice developed a computer program with staff and patients in mind.
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A knowledge-based computer system, designed to assist pathologists in the histological diagnosis of breast disease, is described. This system represents knowledge in the form of "disease profiles" and uses a novel inference model based on the mathematical technique of hypergraphs. Its design overcomes many of the limitations of existing expert system technologies when applied to breast disease. In particular, the system can quickly focus on a differential problem and thus reduce the amount of data necessary to reach a conclusion. The system was tested on two sets of samples, consisting of 14 retrospective cases and five hypothetical cases of breast disease. Its recommendations were judged "correct" by the evaluating pathologist in 15 cases. This study shows the feasibility of providing "decision support" in histopathology.
Computer estimation of the current functional state of the cerebral cortex in rabbits by the EEG data permitted to distinguish its peculiarities in dark and light adaptation of different duration under the action of nembutal; individual peculiarities of the cerebral cortex activity were revealed in various rabbits. The automatic converter system and that of recording and analysis of multiprocess information (apromin system) and computer diagnostic system (mds) were used in complex for the multistage processing of the multiprocess information. Final results are presented on the plane as points reflecting multidimentional images of the current functional states of the cerebral cortex in animals.
Logical principles for the use of computer technology in the assessment of medical information in intensive care units are outlined. A computer system for the assessment of the results of immune status studies has been presented. The potentials are demonstrated to form the data bank with realization of precedent search function, presentation of information with the help of computer graphics and calculation of highly informative secondary indexes on the basis of primary ones.
A computational system is described that predicts the structure of protein/protein and protein/DNA complexes starting from unbound coordinate sets. The approach is (i) a global search with rigid-body docking for complexes with shape complementarity and favourable electrostatics; (ii) use of distance constraints from experimental (or predicted) knowledge of critical residues; (iii) use of pair potential to screen docked complexes and (iv) refinement and further screening by protein-side chain optimisation and interfacial energy minimisation. The system has been applied to model ten protein/protein and eight protein-repressor/DNA (steps i to iii only) complexes. In general a few complexes, one of which is close to the true structure, can be generated.
A portable system for heart screening in school children is deviced and the results of a trial of this machine were reported. This computerized system analyses electrocardiogram and phonocardiogram of school children within two minutes, print out the abnormal codes and simultaneously record the electrocardiogram and phonocardiogram by the visicoder. This system was tried for the primary heart screening in 1,618 pupils and for the secondary heart screening in 372 students. The results were considered to be satisfactory as a primary as well as a secondary heart screening system from the view points of the reliability, the economical condition and the time-saving of the pediatric cardiologist.
Many biomedical experiments require a precisely timed real-time (RT) computer interface. Because commonly used desktop operating systems are inherently non-real-time, real-time laboratory computer systems are often based on outdated DOS software or expensive proprietary real-time operating systems. Here we discuss a real-time computing system, based on the free RT-LINUX operating system, which we have developed for adaptive pacing control in a clinical cardiac electrophysiology laboratory. This powerful, flexible, and inexpensive system demonstrates that RT-LINUX is well suited for real-time biomedical experiment interface.
INTRODUCTION: The computer-based ENG system's analytical routine refinements are available only in research laboratories. The computer-based system contains a stimulator for saccadic eye-movement and an air caloric stimulator interconnected to the registration program and analysis software. Several authors have reported the preoperative and postoperative vestibular functions in cochlear implant patients. The safe examination of the operated ear and comparison of the preoperative and postoperative average slow phase velocities of the caloric nystagmus is possible using the air caloric computer system. METHODS: The authors have used a computer-based ENG system with caloric air stimulation, which is very useful for examination of the operated ear. The vestibular system of patients with total deafness was examined before and after the cochlear implantation. The results of 60 vestibular examinations of 64 patients are reported. RESULTS: The vestibular function in the operated ear was found unchanged in 20 patients. In 14 patients the vestibular function was worse. In 16 patients the postoperative vestibular responsiveness improved. The detailed data analysis of 10 patients in whom preoperative and postoperative vestibular examination was similar was performed by the authors. The preoperative and postoperative average slow phase velocity values and the relative canal paresis was observed. The values demonstrated that the caloric responsiveness of the operated ear improved in few cases. CONCLUSIONS: The computer-based air caloric system is a useful and safe method in evaluation of the vestibular system changes after ear surgery. The reason of the improvement of vestibular responsiveness is not clear. The results need further investigation to solve the problem of vestibular responsiveness improvement after cochlear implantation.
A small multiprocessor system for integrated processing of medical data in a University Hospital is described. It consists of a central computer system to which, at present, two satellite computers are connected, one in the clinical chemistry area and the other in nuclear medicine. The satellite computers collect and present data while the central computer takes over the storage of data and the executive computer-bound programs. A few examples of its use are given and the characteristics of the decentralized system discussed.
A computer system has been used for the recording and display of data from 277 infants with respiratory illnesses consecutively admitted to a neonatal intensive care unit during a period of 25 months. Improved efficiency of data handling was demonstrated, and the system proved valuable for teaching and research.
OBJECTIVE: This study was to development a computer system for assessing bone age which would analyse children's growth level accurately and quickly. METHODS: It used the standards of estimating skeletal maturity for Chinese (CHN) scoring method to assess the bone age of Chinese children. We applied image enhancement techniques for imprving the quality of the hand-wrist radiographs, while an automated system was developed to implement this method. RESULTS: Users could get a clear and reliable radiograph through image processing, compare each bone of the hand-wrist radiograph with that of the scanned image of the standard radiographs, then generate the stage of bone maturity. The computer would give out individual and total bone score and a value of bone age. CONCLUSION: This system implemented evaluation of bone age rapidly and accurately, it would help orthodontist to choose the best time of treatment.
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The Australian Department of Health and Family Services engaged the IBM consulting practice to develop a functional specification and technical architecture for a General Practice computer system (GPCS) in January, 1997. The project was completed in September, 1997. This paper describes the rationale for development of the specification, the process that was undertaken and provides an overview of the completed specification and architecture. The paper also explores a number of issues related to computing in general practice which were raised during the consultative process, and considers factors which were found to be important in obtaining adoption and use of computer technology on the doctor's desk.
A mini-computer system for the automation of pharmacological experiments and for the calculation, printing and storing of results is described. A link between the 1) control unit which powers the pumps, valves, etc., and 2) the computer which processes the digital data allows the synchronization of data collection with the time course of the experiment. Thus results may be immediately expressed in absolute (i.e. stimulus-induced change in tension, etc.) or relative (i.e. % change in response due to drug administration) terms.
OBJECTIVES: To determine the accuracy of diagnoses of schizophrenia and non-affective psychosis entered by general practitioners on a computer system. To compare recording of clinical events on computer with written records. DESIGN: Examination of case notes of all patients with a computer diagnosis of psychosis. Search of 8000 randomly selected patient records to identify patients with psychosis not recorded on computer and comparison of 141 computer and written entries for prescribing and consultation in each practice. SETTING: 13 London practices on the VAMP research bank. MAIN OUTCOME MEASURES: Accuracy of record of psychosis compared with ICD 9, American Psychiatric Association diagnostic manual, and syndrome checklist criteria. RESULTS: Computer search revealed 102 patients with schizophrenia, 78 with other psychoses, and 71 with non-affective psychosis who had adequate case notes. The sensitivity and positive predictive value of the computer diagnosis of schizophrenia were 88% (95% confidence interval 62% to 98%) and 71% (48% to 88%). For all non-organic psychoses sensitivity was 91% (74% to 97%) and positive predictive value was 91% (74% to 98%). On average 95% of all known prescriptions and 74% of all consultations were recorded on computer compared with 42% and 75% in written records. CONCLUSIONS: Recording of psychotic illness on the VAMP computer is accurate and complete. Prescribing was more fully recorded on the computer than on the written records. Computer databases of well motivated general practitioners could be used for research.
The utopian view of the electronic medical record includes the digital transformation of all aspects of patient information. Historically, imagery from the radiology, cardiology, ophthalmology, and pathology departments, as well as the emergency room, has been a morass of paper, film, and other media, isolated within each department's system architecture. In answer to this dilemma, picture archiving and computing systems have become the focal point of efforts to create a single platform for the collection, storage, and distribution of clinical imagery throughout the health care enterprise.
In epidemiological surveillance, it is imperative that any unusual increase in reported cases be detected as quickly as possible. In the surveillance unit at "Pedro Kourí," it was necessary to create a computer system for the surveillance of transmissible diseases in order to manage such variables as morbidity, mortality, and the circulation of causal agents. As usage flexibility is a fundamental requirement, we developed VIGILA as a system readily adaptable to any level of the country's health organizations (national, provincial, or municipal). VIGILA permits the storage, validation, and statistical analysis of morbidity and mortality data, and it also allows the user to apply these features to causal agent information. These manipulations are all performed in the context of a specific transmissible disease. The stored information can be displayed in different types of statistical formats, such as calculated rates, accumulates and medians. The user can also design his/her own tables for display. In addition, the program offers graphics that depict the endemic forecast for a specific region and age group. Reliable forecasts based on temporal models of an epidemiological indicator are necessary for the prediction of the non-epidemic indicator and for the elaboration of an alert threshold. The endemic forecast or endemic channel is calculated by means of a modified version of R. Serfling's model [1] which adapts to data series with stationary characteristics. In this case, the model is fixed for the medical attention protocol and the circulation of agents of a specific transmissible disease. The parameters of the model are estimated by the least square method. The confidence limits are calculated with the T-Student distribution [2]. To enter information about a specific disease and level of health concern, the user must define the disease under analysis, the principal territory under surveillance and its dependencies, the causal agents of the disease, and the frequency with which the disease is reported. This system stores the number of cases (morbidity) and death (mortality) that occurred in the territories and age groups defined during entry. To facilitate the calculation of morbidity and mortality rates, information pertaining to the number of territory habitants and their age groups is also stored. The laboratory data includes the number of analyzed samples in the territories and age groups defined in the data entry, and the samples that were positive to the defined agents. Among the principal uses of the system are: calculation of cumulative cases, rates, and cumulative rates for the specific period of analysis, territory, and age group; comparison of these health indicators with the previous year's indicators or with the median of the previous years' indicators' calculation of the endemic forecast that permits the user to observe the epidemiological situation by territories and age groups; and the early detection of an increase in disease occurrence. The system also offers a geographical representation of the epidemiological situation in the territories, showing a map with the evaluation of each territory with respect to four possible risk factors. VIGILA is available in both DOS and WINDOWS 3.1 formats. This system allows the evaluation of the situation at a specific point in time in the analyzed territories, and may alert the infection control team to an epidemic early enough to allow implementation of control measures.