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Estrogen use and postmenopausal women: a basis for informed decisions. NIH Consensus Development.
A panel of experts convened by the National Institute on Aging, National Institutes of Health, reached the following consensus regarding estrogen use and postmenopausal women. The use of estrogens alleviates vasomotor symptoms and atrophy of the vaginal epithelium and might aid in preventing osteoporosis. However, it increases the incidence of endometrial cancer. The addition of progestins might prevent this complication, but potential risks have not been adequately evaluated. Convincing evidence that postmenopausal estrogen use influences the occurrence of cardiovascular disease and breast cancer does not currently exist. Many aspects of the menopause and its management require further research. Any candidate for postmenopausal estrogen use should be given as much information as possible about both benefits and risks and then, with her physician, reach an individualized decision regarding whether to receive estrogens.
[Contraceptive counseling for young girls].
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Alternatives to adolescent pregnancy: a discussion of the contraceptive literature from 1960 to 1980.
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[Hormonal contraception--side effects and surgical aspects (author's transl)].
Hormonal contraception is at present the safest method to prevent pregnancy. In this survey the most important aspects of side-effects, drug interactions contraindications and indications for discontinuance are dealt with.
[Hormonal contraception and hearing disorders (author's transl)].
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[Ovulation inhibitors in postnecrotic scar liver].
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[Contraception in female heart patients].
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[Contraception in female risk patients].
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[Indications for ovulation inhibitors. Recommendations of the Swiss Society for Family Planning].
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[Effects and side effects of hormonal contraceptives].
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[Internal medicine problems regarding contraception. Part I].
The increasing distaste for the "pill' is mainly due to uncritical comments disseminated by the mass media and to the rational and irrational anxieties of women. The doses of steroidal hormones in today's hormonal contraceptive agents are only a small fraction of the amounts used in the past. Consequently, the occurrence of adverse reactions is much smaller; thus, tendency to thromboembolism has decreased by more than 25% with ovulation inhibitors containing only 50 gamma of EE, and thrombotic incidents are very rare if the so-called "micropill" (30 gamma EE) is given. Hypertension is observed in 1--2.5%, but can be detected by regular blood pressure control. Glucose tolerance is dependent on the estrogen dose and the type of gestagen used. By choosing contraceptive agents with low estrogen doses in combination with a gestagen of the pregnane type, or with the so-called "minipill", the danger of glucose deterioration can be avoided. Plasma triglycerides are markedly increased. The risk of hepatic complications increases with the duration of treatment. Jaundice seems to be mainly due to C17-alkyl substituted steroids. A correlation has been assumed between episodes of pancreatitis and increased lipoprotein concentrations due to treatment with oral contraceptive agents. In contrast, they have a protective effect in rheumatoid arthritis. The absolute and relative contraindications for oral contraceptive agents are listed.
[Oral contraceptives. Experience of the last 10 years].
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[Neuro-ophthalmologic accidents caused by hormonal contraception].
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Family planning and the diabetic mother.
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A practical guide for prescribing birth control pills.
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[Oral contraception in protein C deficiency].
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Pregnancy and birth control in CAPD patients.
This report summarizes the experience with 17 pregnancies in 16 continuous ambulatory peritoneal dialysis (CAPD) patients. Early experience suggests that the outcome of pregnancy in CAPD patients may be better than in hemodialysis patients. Catheter placement can be undertaken during pregnancy with little increased risk. Peritonitis can precipitate premature labor. Blood-tinged dialysate may herald serious obstetric problems. Hypertension, anemia, and prematurity are serious problems in CAPD patients. Cesarean section can be done, with only a brief interruption in CAPD. The major modification of the usual regimen is the need for smaller exchange volumes and increased frequency.