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PubMedDate not supplied

Diseases of the foot: test of radiographic interpretation.

The authors present a variety of radiographic pathologies affecting the foot and ankle. Some of these are intrinsic to the body part, while others reflect more systemic etiologies. Queries are initially posed, answers provided, and then justification of the correct response afforded.

Foot Diseases↗
PubMed2004

Comparison of ELISA for the detection of porcine serum antibodies to non-structural proteins of foot-and-mouth disease virus.

Three foot-and-mouth disease virus non-structural protein antibody detection kits, CHEKIT FMD-3ABC, UBI FMD NS EIA and DVIVR NSP ELISA, were compared in the study. The results showed that the specificity of the kits ranged from 96.7 to 100% in nai;ve pigs and from 93.6 to 98.1% in vaccinated pigs, and that the DVIVR kit had the highest analytical sensitivity. The kappa statistics for the detection of 612 sera were 0.582, 0.447 and 0.658 for CHEKIT/UBI, CHEKIT/DVIVR and UBI/DVIVR, respectively. This study also revealed that measurable non-structural protein specific antibodies in some of infected pigs were sustained either for shorter periods or in intermittent patterns, thus aggravating the difficulties associated with the removal of pre-exposed pigs in the field.

Animals↗
PubMed2002

Dose-dependent responses of sheep inoculated intranasally with a type O foot-and-mouth disease virus.

Unlike foot-and-mouth disease (FMD) in cattle and pigs, which spreads rapidly, resulting in easily detectable foci of clinical infection, the disease in sheep is characterized by restricted transmission, low morbidity and sporadic clinical cases. The study described was designed to investigate whether the ability of sheep to transmit and maintain FMD virus was dose-related. The viral isolate used was known to be associated epidemiologically with rapid fade-out of transmission within sheep flocks. Five separate transmission experiments were performed, with different doses of FMD virus, each experiment containing five intranasally inoculated donor sheep and 10 in-contact recipient sheep. The lowest dose required to cause clinical infection by inoculation (10(4) 50% tissue culture infectious doses; 10(4) TCID50) was also the optimum dose for producing in-contact transmission. Inoculation of donor sheep with higher doses (10(5) and 10(6) TCID50) resulted in reduced transmission, characterized by reduced duration and degree of viraemia and an early humoral and cell-mediated immune response. Principal component analysis was used to interpret the complex interactions of the dose-related responses to infection.

Administration, Intranasal↗
PubMed2005

[Survey of foot and mouth disease in France].

The Foot and Mouth disease is considered a relatively mild disease in susceptible animals but it has a considerable economical impact in France and worldwide due to the huge economical losses that it generates. A system for the prevention of the disease was developed thirty years ago and has since been continuously improved. The current system for the prevention of FMD is based on training and information of all those involved in the surveillance of susceptible animals, over all the national territory, and on the control of imported animals and animal products. This system, developed in close collaboration with the European Commission and the other EU member states, allows control measures to be implemented almost instantaneously, if a case is suspected to avoid spreading of the disease.

Animal Diseases↗