PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “HEART VALVE DISEASES”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 235 records · Page 13Linked to original sources

[Hemodynamic effects of verapamil in pulmonary hypertension caused by heart valve disease].

The authors have investigated the haemodynamic effects of verapamil on the pulmonary circulation by 24 patients suffering from secondary pulmonary hypertension, caused by mitral and/or aortic valve diseases. For this purpose the numeric and graphometric analysis of intracavitary right ventricle pressure curve and pulmonary artery pressure tracing was applied. It was observed a selective antihypertensive effect on the lesser circulation. The pulmonary and systemic systolic tension decreased comparing in percentage 3:1, in case of diastolic tension this comparison was 2:1. The decrease in pulmonary circulation was strongly significant. The diminishing of heart rate and the improving of right heart function was not significant. The elevation of end-diastolic pressure of the right ventricle, just as the shape-analysis of pressure curves suggested right ventricle overload.

Adult↗

[Natural development of old heart valve disease].

The authors report the natural history of 36 patients with end-stage valvular disease defined by the presence of a functional stage IV and/or a 0.60 and/or dilatation of the LA 90 mm and/or dilatation of the LV 70 mm and/or increase in the systolic PAP 80 mmHg and/or a decrease in the EF of 0.45. 11 patients are alive with a mean survival of 36.8 months (30.5%) and 25 have died after a mean interval of 7.8 months. The prognosis is very poor for aortic valvular disease (14 deaths out of 16 cases), but there were only 3 deaths out of 10 patients with isolated mitral valve disease.

Adult↗

[Roentgenologic evaluation of myocardial contractility in heart valve diseases].

The authors compare the roentgenological findings with the parameters of contractility obtained during heart catheterization in 49 patients with mitral valvular disease and aortal valvular disease. The parameters are shown to be correlated with regard to the nature of valvular damage, characteristics of the impairment of the intracardiac hemodynamics and myocardial contractile function. Certain tendencies of this dependence are tabulated.

Adolescent↗

[Interventional treatment of heart valve diseases].

Percutaneous balloon valvuloplasty of stenoses has been introduced into medical practice in the late 70ies. Over the past decade, the method has evolved to a valid alternative to valve surgery in selected cases. Balloon valvuloplasty of isolated mitral stenosis is to date the therapy of choice and yields results comparable to those of surgery. It is even superior in only moderately diseased valves. However, the most frequent valve stenosis, that is aortic stenosis of the elderly, is not suitable for balloon dilatation. Dilatation of congenital aortic stenosis can be attempted if the valve is bicuspid or tricuspid. The recurrence rates for valvular stenoses after valvuloplasty are similar to those after surgical commissurotomy.

Aged↗

The effect of left ventricular function on the echocardiographic assessment of heart valve disease.

Transvalvar velocities or derived pressure differences are highly dependent on flow. They must be corrected for flow for research studies or in the clinical situation where values are intermediate and difficult to interpret. This can be done using the continuity equation or using formulae based on ratios of mean pressure drop and flow of which resistance is probably more accurate than the Gorlin formula. Left ventricular diastolic behavior is a major determinant of mitral pressure half-time where the mitral stenosis is mild and also of the slope of the continuous wave recording in mild or moderate aortic regurgitation. Methods for assessing mitral regurgitation including patterns of pulmonary vein flow are also dependent on left ventricular function. The echocardiographic methods of describing valve function cannot be interpreted without regard to left ventricular function and loading conditions.

Aortic Valve Insufficiency↗

[Takayasu arteritis associated with heart valve diseases (pulmonary and aortic) and arteritis (coronary and renal)].

The most severe arteritis due to Takayasu's disease are those related to renal and coronary arteries. The first one because it produces severe arterial hypertension and the second one because it puts the patient in high risk of suffering either myocardial ischemia or infarction. These situations worsen when this entity is associated to valvular heart lesions. The authors present the clinical cases of two female patients with Takayasu's disease. One of them in acute phase of the illness, where coronary arteritis, mild coarctation of the aorta, right pulmonary artery stenosis, and pulmonary valve stenosis were present. The second patient was seen during the remission phase of the disease with obstruction of the left subclavicular artery, renal arteritis, severe arterial hypertension and aortic valve insufficiency. The authors discuss the prognosis of patients with Takayasu's disease associated to valvular heart disease and its role in the etiology of pulmonary valvular stenosis. Finally, the authors point out the importance of recognizing the active and non active phases of the Takayasu's disease in relation of the adequate stage for surgical treatment of the lesions caused by this disease.

Adult↗

[A rapidly growing heart valve disease: degenerative aortic stenosis; diagnostic and therapeutic aspects].

Ostial aortic stenosis is clearly the commonest form of valvular heart disease in adults at the present time, as it represents 26% of all forms of valvular heart disease and 2% of all forms of heart disease. It is a disease middle and old-age, which appears to becoming increasingly frequent due to ageing of the population. It affects men twice as often as women and sometimes has a misleading clinical presentation at the stage of heart failure due to disappearance of the usual systolic murmur. The patient may simply present with signs of refractory left ventricular failure or complete heart failure. The diagnosis and follow-up have been radically transformed by the development of Doppler ultrasonography which allows the positive diagnosis as well as a very precise assessment of the severity, avoiding the need for cardiac catheterization, but unfortunately coronary angiography still remains essential in view of the age of these patients. In terms of treatment, percutaneous valvuloplasty according to the method developed by Cribier has unfortunately not lived up to expectations and tight aortic stenosis remains a surgical disease whose results are among the most spectacular: the patient's dramatic functional and objective transformation following insertion of a valvular prosthesis (mechanical before the age of 75 years, bioprosthesis after this age), at the cost of a reasonable operative mortality of approximately 5 to 8% in the 71 to 80 year age-group, must be stressed.

Aged↗

[Accidental fall and word finding problems in heart valve disease].

Abscesses of the spleen are rare and, if untreated, lead to death. The usual mode of development is by hematogenous spread of infection. Treatment options are splenectomy, percutaneous drainage and in selected cases an antibiotic therapy. We report a case of a splenic abscess due to Streptococcus bovis treated with antibiotics only.

Abdominal Abscess↗

[Can Doppler echocardiography help to avoid cardiac catheterization in the surgical decision-making in isolated left heart valve diseases?].

The aim of this study was to assess the value of non-invasive investigation based on clinical evaluation and Doppler echography in deciding the operative indications of patients with isolated left heart valvular lesions compared. Three hundred and thirty five patients were included in a prospective study: 78 had MR, 57 had AR, 150 had AS and 50 had MS. All underwent clinical. Doppler echography and catheter studies. The therapeutic decision was taken blind by two groups of 2 cardiologists. Group I took its decision based on clinical findings and results of Doppler echography whilst Group II took its decision on the clinical and catheter data. For each patient, one of the following three choices was proposed: 1) medical treatment: 2) surgery or valvuloplasty with balloon catheter; 3) request for further information. In addition, in group I, the need for coronary angiography was left to the appreciation of two cardiologists. The quantification of the valvular disease was concordant for groups I and II in 93, 97, 98.5 and 100% for MR, AR, AS and MS respectively. These percentages were respectively 97, 95, 92 and 100% for assessment of left ventricular function. The theoretical management decision was concordant between the two groups for 97% of MR, 94.7% of AR, 95.3% of AS and 94% of MS. Complementary information requiring invasive studies was required by group I in 3.9% of cases. A discordant opinion was obtained in 0.6% of cases (2 cases of AS). Coronary angiography was requested by the cardiologists of Group I in 34% of patients, identifying all patients who underwent coronary bypass surgery. These results show that cardiac catheterisation is no longer an essential diagnostic procedure for discussing the indications of valvular surgery in the majority of patients with isolated left heart lesions.

Adult↗

[Periarteritis nodosa with heart valve disease disclosed by occlusion of the central artery of the retina].

We report a case of periarteritis nodosa revealed by blindness due to occlusion of the central retinal artery. The disease appeared after a serous otitis and was accompanied by thrombocytosis. Its outcome was favourable under corticosteroid therapy, but it was complicated by aortic valve regurgitation. Lesions of fibrinoid necrosis were found on the aortic cusps removed during surgical replacement. It seems highly probable that the ocular and valvular lesions were specific, although this cannot be directly demonstrated. The case presented here is exceptional, and the relevant literature is reviewed.

Aortic Valve↗