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At least 235 records · Page 13Linked to original sources
PubMedDate not supplied

Planned NLM/AHCPR large-scale vocabulary test: using UMLS technology to determine the extent to which controlled vocabularies cover terminology needed for health care and public health.

The National Library of Medicine (NLM) and the Agency for Health Care Policy and Research (AHCPR) are sponsoring a test to determine the extent to which a combination of existing health-related terminologies covers vocabulary needed in health information systems. The test vocabularies are the 30 that are fully or partially represented in the 1996 edition of the Unified Medical Language System (UMLS) Metathesaurus, plus three planned additions: the portions of SNOMED International not in the 1996 Metathesaurus Read Clinical Classification, and the Logical Observations Identifiers, Names, and Codes (LOINC) system. These vocabularies are available to testers through a special interface to the Internet-based UMLS Knowledge Source Server. The test will determine the ability of the test vocabularies to serve as a source of controlled vocabulary for health data systems and applications. It should provide the basis for realistic resource estimates for developing and maintaining a comprehensive "standard" health vocabulary that is based on existing terminologies.

Computer Communication Networks↗
PubMedDate not supplied

Emphysematous infections of the abdomen and pelvis: a pictorial review.

Emphysematous (gas-forming) infections of the abdomen and pelvis represent potentially life-threatening conditions that require aggressive medical and often surgical management. The initial clinical manifestation of these entities may be insidious, but rapid progression to sepsis will occur in the absence of early therapeutic intervention. Conventional radiography and ultrasonography are often the initial imaging modalities used to evaluate patients with abdominopelvic complaints. However, when a differential diagnosis remains, or if further localization or confirmation of tentative findings is needed, computed tomography (CT) should be considered the imaging modality of choice. CT is both highly sensitive and specific in the detection of abnormal gas and well suited to reliable depiction of the anatomic location and extent of the gas. Of equal importance may be the capability of CT to help reliably identify benign sources of gas, because treatment (if any) varies dramatically depending on the source. Knowledge of the pathophysiologic characteristics, common predisposing conditions, and typical imaging features associated with gas-forming infections of the gallbladder, stomach, pancreas, and genitourinary system will help make early diagnosis and successful treatment possible. In addition, such knowledge will aid in further diagnostic work-up, surveillance of potential complications, and evaluation of therapeutic response.

Aged↗
PubMed2005

Exploring the boundaries: gene and protein identification in biomedical text.

BACKGROUND: Good automatic information extraction tools offer hope for automatic processing of the exploding biomedical literature, and successful named entity recognition is a key component for such tools. METHODS: We present a maximum-entropy based system incorporating a diverse set of features for identifying gene and protein names in biomedical abstracts. RESULTS: This system was entered in the BioCreative comparative evaluation and achieved a precision of 0.83 and recall of 0.84 in the "open" evaluation and a precision of 0.78 and recall of 0.85 in the "closed" evaluation. CONCLUSION: Central contributions are rich use of features derived from the training data at multiple levels of granularity, a focus on correctly identifying entity boundaries, and the innovative use of several external knowledge sources including full MEDLINE abstracts and web searches.

Biomedical Research↗
PubMed1977

Application of knowledge about prevention in social work education and practice.

The status of preventive social work in the United States is reviewed, as are the three knowledge sources used in the teaching and practice of prevention: public health, mental health, and social work. The integration of concepts of prevention in social work curricula and practice are discussed, and new directions for its use are projected.

Curriculum↗
PubMed1998

Peer counseling in a culturally specific adolescent pregnancy prevention program.

This study evaluated the effects of peer counseling in a culturally specific adolescent pregnancy prevention program for African American females. A random pretest and multiple posttest experimental and comparison group design was used to obtain data on a sample of 63 female African American adolescents, ages 12 to 16, who lived in four public housing developments. Descriptive data and tests of significance revealed that none of the participants who received peer counseling became pregnant within three months of the intervention. Findings revealed a statistically significant increase in reproductive and other self-related knowledge topics among the experimental group when comparing pretest and eight-week posttest scores. Most participants had not had sexual intercourse; the average age of sexual onset was 12 years in the experimental group and 11 years in the controls. Designing and implementing culturally specific adolescent pregnancy prevention programs for adolescents younger than age 11 and/or before sexually active seems appropriate.

Adolescent↗
PubMed2001

Effects of endophyte status of tall fescue tissues on the earthworm (Eisenia fetida).

A cryptic fungal endophyte, Neotyphodium coenophialum, infects most tall fescue (Festuca arundinacea) pastures in the United States. Cattle, sheep, and horses that consume the endophyte-infected grass can suffer fescue toxicosis caused by toxic alkaloids in the infected plants. The effects of the endophyte on mammalian herbivores have been well documented, but less is known regarding the quality of the grass (infected vs noninfected) as a food material for soil invertebrates. We conducted 21-d tests with earthworms (Eisenia fetida) to determine the nutritional quality of endophyte-infected and noninfected tall fescue leaf and root tissues. Earthworm survival, growth, and reproduction were measured in each treatment combination of tissue type and infection status. Earthworm survival was 100% in all treatments. Tall fescue tissue type (leaf vs root) and infection status (present or absent) both significantly affected E. fetida growth and reproduction. The earthworms grew and had moderate levels of reproduction in replicates containing tall fescue leaf tissue as the sole food source regardless of the endophyte-infection status, but earthworms lost weight and had less reproduction in replicates where tall fescue root tissue was the sole food source. An unexpected effect of infection status on earthworm growth in the tall fescue leaf-tissue treatments was also evident: mean growth of E. fetida with access to endophyte-infected leaf tissue as the sole food source was 3.6-fold greater than mean growth of E. fetida with access to noninfected leaf tissue as the sole food source. Knowledge regarding the relative effects of endophyte status of tall fescue on soil organisms may allow the development of more effective environmental management strategies at sites where tall fescue is being considered for use in phytoremediation or for vegetative cover. Investigators working with tall fescue should be alert to the possibility of endophyte-mediated effects of tall fescue on other organisms and, at a minimum, should provide information regarding the grass's infection status when reporting the results of studies that involve use of tall fescue.

Animals↗
PubMed1976

Community resources--why should we use them.

Professionals working with low vision persons may find themselves in the situation where they are either the first or only contact known to their patient. Because one person is usually not able to fulfill the diverse needs of the visually impaired individual, he may find it necessary to refer patients to other sources. Knowledge of the role of other related professionals and their availability in the community may make the difference between a fragmetned receipt of services or a total approach to vision rehabilitation.

Adult↗
PubMed1998

Building cross-thesauri with the support of UMLS.

The absence of a robust system of descriptors (cross-thesaurus) hampers the development of combinatorial terminological systems. We developed a tool (I-BROWSE) to produce a cross-thesaurus by analyzing terminological corpora. To facilitate the work of experts and to produce re-usable results, our application interacts via the Internet with the UMLS Knowledge Sources Server. We applied our tool on 2999 dissections on surgical procedures produced in the project GALEN-IN-USE, as a part of the internal Quality Assurance program. Support from UMLS seems mostly promising about descriptors on , , and . Additional assistance can be given to domain experts on less frequent descriptors on pervasive modifiers. We plan to apply our tool also to production of terminological standards in CEN, as a part of a worldwide process of gradual convergence and transformation of coding systems into second-generation systems and terminological services.

Artificial Intelligence↗
PubMed1999

Influence of the Digital Anatomist Foundational Model on traditional representations of anatomical concepts.

A principled and logical representation of the structure of the human body has led to conflicts with traditional representations of the same knowledge by anatomy textbooks. The examples which illustrate resolution of these conflicts suggest that stricter requirements must be met for semantic consistency, expressivity and specificity by knowledge sources intended to support inference than by textbooks and term lists. These next-generation resources should influence traditional concept representation, rather than be constrained by convention.

Anatomy↗
PubMed2000

MedSynDiKATe--design considerations for an ontology-based medical text understanding system.

MedSynDiKATe is a natural language processor for automatically acquiring knowledge from medical finding reports. The content of these documents is transferred to formal representation structures which constitute a corresponding text knowledge base. The general system architecture we present integrates requirements from the analysis of single sentences, as well as those of referentially linked sentences forming cohesive texts. The strong demands MedSynDiKATe poses to the availability of expressive knowledge sources are accounted for by two alternative approaches to (semi)automatic ontology engineering.

Evaluation Studies as Topic↗
PubMed1997

[Historian and physician as researchers of the history of medical sciences].

It can be observed that recently the historiography of medical sciences has anew searched for its own identity and its place among other medical and historical sciences. On the one hand, the researchers in this field are not physicians exclusively any longer but more and more frequently the representatives of other medical professions and professional historians, as well. On the other hand, the major direction of interest to the history of medical sciences, i.e. cultivating the traditions of medical professions and molding the attitudes of environments related with them is not sufficient in the long run. The variety of extra source knowledge, shared in the community of researches, diverse research approaches, hierarchy of problems worth studying and, finally scientific traditions individual research groups derive from have produced a significant ferment in the medical environments. At last disputes have been held, although quite often unofficially during various scientific meetings, on professional qualification of a historian of medical sciences and sometimes on the scope of his or her discipline. The author analyzes in detail the divergence in the features of individual study approaches for both groups and their consequences. The author's standpoint is that it is necessary to be aware of the diverse study approaches and hierarchy of problem eligible for studying to break the distinction and create interdisciplinary units. This will allow an interparadigmatic dialog, a professional division of work and search for the area of common interest, while retaining methodological autonomic features.

Historiography↗
PubMed2002

Towards a semantic medical Web: HealthCyberMap's tool for building an RDF metadata base of health information resources based on the Qualified Dublin Core Metadata Set.

BACKGROUND: HealthCyberMap (http://healthcybermap.semanticweb.org/) aims at mapping Internet health information resources in novel ways for enhanced retrieval and navigation. This is achieved by collecting appropriate resource metadata in an unambiguous form that preserves semantics. MATERIAL/METHODS: We modelled a qualified Dublin Core (DC) metadata set ontology with extra elements for resource quality and geographical provenance in Prot g -2000. A metadata collection form helps acquiring resource instance data within Prot g . The DC subject field is populated with UMLS terms directly imported from UMLS Knowledge Source Server using UMLS tab, a Prot g -2000 plug-in. The project is saved in RDFS/RDF. RESULTS: The ontology and associated form serve as a free tool for building and maintaining an RDF medical resource metadata base. The UMLS tab enables browsing and searching for concepts that best describe a resource, and importing them to DC subject fields. The resultant metadata base can be used with a search and inference engine, and have textual and/or visual navigation interface(s) applied to it, to ultimately build a medical Semantic Web portal. Different ways of exploiting Prot g -2000 RDF output are discussed. CONCLUSIONS: By making the context and semantics of resources, not merely their raw text and formatting, amenable to computer 'understanding,' we can build a Semantic Web that is more useful to humans than the current Web. This requires proper use of metadata and ontologies. Clinical codes can reliably describe the subjects of medical resources, establish the semantic relationships (as defined by underlying coding scheme) between related resources, and automate their topical categorisation.

Humans↗
PubMed1992

Fearing to give life.

Explore the source record for details and available documents.

Acquired Immunodeficiency Syndrome↗
PubMed2001

Methodologic Issues in Neuropsychological Testing.

OBJECTIVE: To familiarize athletic trainers with methodologic issues regarding the development and implementation of neuropsychological tests used in programs for monitoring sport-related cerebral concussion. DATA SOURCES: Knowledge base and MEDLINE and PsychLit searches from 1980-2000 using the terms sports, athletes, concussion, and brain. DATA SYNTHESIS: Neuropsychological testing is a proven method for evaluating symptoms of concussion that results from a variety of different causes. These tests have been shown to be effective in evaluating symptoms of subtle cognitive dysfunction in a number of patient groups. Applying these tests in an athletic population has required some procedural modifications, including the use of brief test batteries, collection of preseason baseline data, and evaluation of subtle postconcussive changes in test scores over time. New methods are now being used for improved evaluation of the reliability and validity of neuropsychological tests in athletes. Proper scientific analysis of the psychometric properties of neuropsychological tests and the ultimate value of their use in the sport setting will require years of detailed study on large numbers of athletes with and without symptoms of concussion. CONCLUSIONS/RECOMMENDATIONS: Athletic trainers and related personnel need to be aware of the training and methodologic issues associated with neuropsychological testing. Knowledge of the scientific properties of these tests, their advantages, and current limitations will ultimately enhance the athletic trainer's ability to use information from neuropsychological testing in an effective manner.

Journal Article↗
PubMed2003

Coverage of patient safety terms in the UMLS metathesaurus.

The integration and large-scale analyses of medical error databases would be greatly facilitated by the use of a standard terminology. We investigated the availability in the UMLS metathesaurus of concepts that are required for coding patient safety data. Terms from three proprietary patient safety terminologies were mapped to the concepts in UMLS by an automated mapping program developed by us. From these candidate mappings, the concept that matched its corresponding term was selected manually. The reliability of the mapping procedure was verified by manually searching for terms in the UMLS Knowledge Source Server. Matching concepts in UMLS were identified for less than 27% of the terms in the study dataset. The matching rates of terms that describe the type of error and the causes of errors were even lower. The lack of such terms in the existing standard terminologies underscores the need for development of a standard patient safety terminology.

Humans↗