PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “LABOR, INDUCED”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 235 records · Page 13Linked to original sources
PubMed1980

[Effectiveness of different treatment regimens for inducing labor in sows with prostaglandin F2 alpha].

2 experiments were applied to 401 gilts and sows to verify the effects of different injection dates and PGF2 alpha doses (Prostin F2 alpha) on the beginning and duration of parturition. PGF2 alpha was intramuscularly injected on the 112th or 113th days of pregnancy. Doses were 5.0 mg or 7.5 mg, 10.0 mg or 12.5 mg. One single injection of not less than 7.5 mg of PGF2 alpha from the 112th day of pregnancy caused normal births within 48 hours from injection in more than 85 per cent of the animals involved, with farrowing after the 116th day of pregnancy being ruled out. No correlatons were secured between litter sizes of treated sows and the time which elapsed between treatment and partiturition.

Animals↗
PubMedDate not supplied

[Induced labor with prostaglandins: 0.5 mg PGE2 intracervical gel versus 3 mg PGE2 vaginal tablet].

For the induction of labour prostaglandin (PG) E2 has been recommended either as intracervical gel (0.5 mg) or as vaginal tablet (3 mg) depending on the Bishop score of the cervix. A prospective trial was conducted in 79, mainly postterm, pregnancies (59 with a Bishop score < 5), in whom either PG-E2 tablet or gel was given randomly without respect to the cervical score. In addition, 51 inductions in primiparous women (44 with a Bishop score < 5) were analysed retrospectively. In pregnancies with a Bishop score < 5 the rate of successful inductions, duration of labour or incidence of neonatal acidosis was not different in both groups. Similar results were obtained in the prospective trial for inductions with a cervical score > 4. These data suggest the lack of superiority of the intracervical over the vaginal route of PG-E2 administration for the induction of labour.

Administration, Intravaginal↗
PubMed1995

[Uterine reactions to prostaglandins in induced labor--results of a multicenter study].

During a prospective multicentric study concerning labor induction with prostaglandins 1472 prostaglandin-inductions were documented. With a Bishop Score < 5 a gel containing 0.5 mg of PgE2 was applied intracervically, with a Bishop Score > = 5 a tablet containing 3 mg of PgE2 was applied retrocervically inside vagina. In case of lacking success the application was repeated after 6 to 8 hours and after 24 hours according to the actual Bishop-Score. Coordinated labor after application of PG-gel or PG-tablet was observed in 85.2% (83.3% respectively), polycystolia or tetani in 13.9% of cases (9.1% respectively). Differences were not statistically significant. Uterine reactions started in the mean 5-6 hours after the last PG-application, but intervals showed a significant spreading among single cases. In 16.0% of the patients successfully treated with Pg-gel and in 8.3% of the patients successfully treated with a PG-tablet due to a uterine hyperstimulation a tocolytic treatment became necessary. With a ripe cervical score (Bishop-Score > 7 points) a significant shortening of the induction-interval was observed.

Administration, Intravaginal↗
PubMedDate not supplied

Effect of preinduction cervical softening with dinoprostone gel on outcome of oxytocin-induced labor.

Five hundred fourteen pregnant women at or near term with medically indicated inductions and unfavorable cervical induction features (Bishop score 0-4) were enrolled in an open-label randomized multicenter clinical trial to study the effect of endocervical administration of 0.5 mg of dinoprostone cervical gel as a preinduction cervical ripening agent. Patients in the treatment group (n = 265) received dinoprostone cervical gel 12 hours prior to oxytocin induction; patients in the control group (n = 249) were observed during this period. Thirteen patients in each group were excluded from efficacy evaluations. All patients were included in safety analysis. A mean Bishop score increase of 2.9 points was achieved in the treatment group, as compared with 0.6 point in the control group (P < 0.001). During the observation period, spontaneous labor occurred in a significantly greater percentage of patients in the treatment group (27%) than in the control group (2%). The percentage of patients who achieved labor either during the observation period or during the initial induction attempt was significantly larger in the dinoprostone cervical gel group (71.8%) than in the control group (54.2%). In addition, there was a statistically significant (P < 0.001) difference in median induction-to-vaginal delivery time for the treatment group (10.6 hr) and the control group (13.0 hr). Side effects were reported for 42% and 35% of patients in the treatment and control groups, respectively, with fetal heart rate abnormalities reported for approximately 27% of patients in each group.(ABSTRACT TRUNCATED AT 250 WORDS)

Administration, Intravaginal↗