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Results for “MYOSITIS OSSIFICANS”

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PubMed1993

Circumscribed myositis ossificans. Report of nine cases without history of injury.

The clinical features of 9 patients with circumscribed myositis ossificans (CMO) are described and the effects of treatment with surgical removal of ectopic bone are assessed. The average age of these patients was 24.4 years, and the average follow-up period was 7.4 years. Early correct diagnosis remains unusual, mainly because myositis may be mistaken for bruising, sarcoma or mumps. Once histological diagnosis was established in biopsy, surgical resection of the mass was found in these series. Although spontaneous recurrence was found in this series. Although spontaneous regression of the clinical findings has been reported, we consider surgery to be necessary in CMO in order to establish the diagnosis; furthermore, when the clinical and radiological diagnosis is uncertain or when the lesion causes pain or mechanical blocking of a joint, the removal of the mass is mandatory.

Adolescent↗
PubMed1976

Myositis ossificans progressiva with parathyroid hyperplasia and polycystic ovary.

A report was made on an autopsy case of myositis ossificans progressiva in a girl who died at the age of 8 year and 11 months. The first symptom appeared as right wryneck ten days after birth. Parathyroid hyperplasia and polycystic ovary with high level of serum parathyroid hormone, FSH and LH were confirmed at autopsy. Parathyroid hyperactivity might be a secondary response to the continuous stimulation by increased peripheral consumption of calcium ions due to relentlessly progressive ossification in fibrous connective tissue.

Child↗
PubMed1998

Myositis ossificans progressiva: five generations where the disease was exclusively limited to the maxillofacial region. A case report.

Myositis ossificans progressiva is an unusual autosomal-dominant inherited disease characterized by congenital malformations and osseous metaplasia of the fascia of the muscles and connective tissue leading to ossification of the relevant area. The case report is remarkable in that eight members of the same family over five generations manifested the exclusive localization of the disease in the maxillofacial region.

Adult↗
PubMed2006

Bilateral and recurrent myositis ossificans in an athlete: a case report and review of treatment options.

An unusual case of recurrent myositis ossificans (MO) bilaterally in the hamstring muscles of a 47-year-old athlete secondary to trauma is presented with a review of the literature of current treatment options. MO is a common condition that occurs among athletes in association with muscle and/or tendon strain or contusion. After an extensive literature review, we believe this to be the first case reported of recurrent and bilateral MO in a nonsurgical setting from recurrent hamstring strains. Plain radiographs and physical examination revealed the appearance and chronology of this pathology. Treatment options to improve flexibility and decrease morbidity are discussed along with prophylaxis for future injury. Treatment of mobility and flexibility, rehabilitation goals and treatment with nonsteroidal anti-inflammatory drugs, bisphosphonates, and magnesium are discussed along with prophylaxis.

Baseball↗
PubMed2003

Myositis ossificans and fibroosseous pseudotumor of digits: a clinicopathological review of 64 cases with emphasis on diagnostic pitfalls.

Myositis ossificans (MO) and fibroosseous pseudotumor of digits (FP) are pseudotumoral mimics of malignancy. A review of 50 cases of MO and 14 cases of FP showed that a malignant diagnosis was suggested by referring pathologists in 23% of MO and 9% of FP. The most common misdiagnosis was osteosarcoma. Awareness of the spectrum of clinicopathological features of MO and FP will help pathologists avoid misdiagnoses. A comparison of the clinicopathological features of MO and FP showed that most features were similar, but FP involved an older age group (p<0.001). MO showed a statistically significant higher tendency to contain fibrinous material (p=0.007), edematous lymphangioma-like areas (p=0.013), and cartilage (p=0.017) and FP to contain excessive immature osteoid (p=0.029). These differences may be related to the site of occurrence.

Adolescent↗
PubMed2006

Pseudomalignant myositis ossificans of the proximal phalanx: a report of two cases.

This report presents two cases of pseudomalignant myositis ossificans (PMO) of the fifth proximal phalanx and their management. The charts, X-rays, pathology specimens, and clinical outcome for two patients treated for PMO were retrospectively reviewed. Both patients presented with isolated swelling and pain over the proximal phalanx of the fifth digit and underwent biopsy of the lesions. In both cases the pathology results were conclusive for PMO. Both patients had improvement in pain and swelling postoperatively. There was no recurrence in either patient. PMO can easily be confused with a malignancy. Proper workup, including biopsy, should be performed in order to accurately make the diagnosis. Radical procedures or amputations should not be performed until a diagnosis has been made. Excision is indicated when nerve compression or loss of joint motion secondary to mass effect occurs. Historically, recurrence has not been a problem after excision.

Adult↗
PubMed1979

Ultrasound appearance of myositis ossificans.

Ultrasonic evaluation of a soft tissue mass of the thigh was performed and suggested the diagnosis of myositis ossificans. Correlation with routine radiographic studies is made, as well as with the follow-up radiographic examination.

Adult↗
PubMed1976

Myositis ossificans progressiva. Clinical features of eight patients and their response to treatment.

The clinical features of eight patients with myositis ossificans progressiva are described and the effects of treatment with the diphosphonate EHDP, together with surgical removal of ectopic bone, are assessed. Early correct diagnosis remains unusual, mainly because the significance of the short great toes is unrecognised, and because myositis may be mistaken for bruising, sarcoma or mumps. The diphosphonate disodium etidronate (EDHP) was given to all patients in an attempt to suppress calcification of new lesions; in five of them ectopic bone was removed during the treatment. EHDP sometimes delayed the mineralisation of newly formed bone matrix after surgical removal but this delay could not be predicted. The variable effect of EHDP may depend particularly on the amount absorbed and on the activity of new bone formation.

Adolescent↗
PubMed1982

Myositis ossificans circumscripta in para/tetraplegics.

At the Hospital of Physical Medicine, Hornbaek, we analysed in retrospect 52 cases of myositis ossificans circumscripta (MOC) among 605 patients with para/tetraplegia. MOC proved significantly more common after total than after subtotal spinal cord injuries. MOC was not observed in any case above the motor level of the spinal cord lesion. This neurological relationship appears to "explain" the finding that MOC is more common in para/tetraplegia of traumatic origin (more complete spinal cord lesions) than among those caused by slipped discs or tumours. Twenty-five per cent of the patients ended up with fairly mild and 12% with more severe hip contractures, the latter causing recurrent, contralateral decubital ulcers over the ischial tuberosity and protracted hospitalization. To aid diagnosis, the authors suggest a simple programme for all para/tetraplegics. In our opinion, routine X-ray examination is not necessary. Intensified research into the causative factors and treatment is needed, not only to facilitate these patients' social adaptation, but also for socio-economic reasons.

Adolescent↗
PubMed2001

[Myositis ossificans and other ossifying lesions of the soft tissues].

Knowledge of the clinical history and typical imaging characteristics of myositis ossificans is important as identification of this entity will avoid unnecessary and invasive work-up. Conversely, the radiologist must pay attention to any atypical clinical or imaging finding, which will warrant further investigations.

Diagnosis, Differential↗
PubMed1990

[Non-traumatic circumscribed myositis ossificans in the femoral region].

The authors report the main clinical and radiographic aspects of non-traumatic circumscribed myositis ossificans in a 12 year-old child. These observations provide useful information for making a diagnosis. CT scan showed the presence of two distinct areas, a lucent central area and a dense outer area whose appearance suggest the presence of calcium. The main differential diagnosis concerned tumors in the soft bone tissue which necessitated regular clinical and paraclinical follow-up.

Child↗
PubMed1976

Treatment of traumatic myositis ossificans circumscripta; use of aspiration and steroids.

The classification, clinical presentation, forms of treatment, and theories of pathogenesis of traumatic myositis ossificans circumscripta are reviewed. A group of 7 patients with this lesion was treated with hematoma aspiration and injection of steroids, lysosomal enzymes, and xylocaine, resulting in significant limitation of disability. The determining factor in the development of this disorder seems to be the response of local soft tissues to trauma rather than the magnitude of the trauma itself which we feel accounts for the success of the form of treatment described.

Adolescent↗