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At least 235 records · Page 13Linked to original sources
PubMed1985

[An autopsy case of triple cancer associated with superior vena cava syndrome].

In recent years, because of advances in diagnostic techniques and therapy for malignant tumors, it is not rare to encounter cases of primary multiple malignant neoplasms. However, triple cancer is still rare. We report a case of triple cancer--gastric cancer, sigmoid colon cancer and malignant fibrous histiocytoma. To our regret, we could not make a diagnosis while the patient was alive. Careful examination of a cancer patient is important because malignant tumors may develop at any time.

Adenocarcinoma↗
PubMed1991

Sudden death of an elderly man with multiple malignant neoplasms.

With the lengthening of the human life span, cancer has become an increasingly important medical problem for the aged. It is not uncommon to find multiple primary neoplasms in elderly individuals. We recently investigated the death of an elderly man who had died suddenly and had three incidental malignant neoplasms, including a pleural mesothelioma, first diagnosed at autopsy. The importance of performing a complete medicolegal autopsy for epidemiological and statistical purposes is emphasized.

Adenocarcinoma↗
PubMed1985

Three synchronous multiorgan primary cancers. All stage I.

A patient who has three separate, synchronous, early (stage I) primary cancers of the right lung, right breast, and stomach and whose disease is simultaneously diagnosed and successfully treated sequentially within a single hospital admission is unique. While multiple primary malignant neoplasms are not uncommon, to our knowledge, there has been no report of triple stage I synchronous carcinomas in separate major organ systems. Age, immunodeficiency, somatotype, hereditary tendencies, hormonal and environmental factors, and previous therapy have been incriminated as etiologic factors. Accurate tissue diagnosis and tumor staging are mandatory. In patients with diagnosed cancer, pulmonary lesions should never be presumed metastatic. Individual tumors should be treated independently of other concomitant lesions, and each treatment approach should be curative in nature. Patients with proven multiple malignant neoplasms carry a higher risk of developing other primary neoplasms.

Aged↗
PubMed1989

[Studies on association between the ATL and the development of multiple malignant neoplasms--analysis of 1171 cases of hematological malignancies during the past 24 years].

A high incidence of multiple primary neoplasms has been observed in our patients with ATL in comparison to persons with other forms of hematologic malignancy who we have observed during the past 24 years (1963-1985). Five of 15 patients with ATL (33.3%) have had at least one other associated neoplasm in comparison to only 44 of 1156 patients with other forms of hematological malignancy (3.8%). The incidence figures for secondary neoplasms associated with the other hematologic malignancies were 4.3% (16/370) for acute non-lymphocytic leukemia (ANLL), 2.2% (2/90) for acute lymphocytic leukemia (ALL), 4.8% (1/21) for acute unclassifiable leukemia, 2.2% (5/225) for chronic myelogenous leukemia, 4.7% (2/43) for chronic lymphocytic leukemia, 5.9% (8/136) for malignant monoclonal gammopathy and 3.7% (10/271) for malignant lymphoma. The incidence of multiple neoplasms in patients with ATL in comparison to those with other hematological malignancies was significant (p less than 0.01 or p less than 0.001). The neoplasms associated with ATL have been adenocarcinoma of the thyroid or lung, and squamous cell carcinoma of the larynx, lip or lung. We identified ATL-derived factor (ADF) in the cytoplasm of the secondary neoplasms of the ATL patients by means of indirect immunofluoroscopy and immunohistochemical techniques utilizing anti-ADF antibody. We also identified ras p21 products in these neoplasms by means of p21 ras monoclonal antibody studies. The possibility that HTLV-I was the cause of the secondary neoplasms thus was investigated.(ABSTRACT TRUNCATED AT 250 WORDS)

Cytokines↗
PubMed1987

Primary pulmonary angiosarcoma associated with multiple synchronous neoplasms.

A 60-year-old man presented with a 3-month history of shortness of breath. He was found to have a right thoracic mass involving the right middle and lower lobes, pulmonary hilum, and mediastinum. Diagnosis could not be established by pleural fluid cytology, pleural biopsies, bronchoscopy, and ultrasound-guided needle biopsies. A diagnostic exploratory thoracotomy was performed. Massive hemorrhage was encountered upon opening the pleura, and bleeding was controlled by performing a radical pneumonectomy. Histology revealed angiosarcoma, pulmonary primary. The patient survived for 68 days. At autopsy, he was found to have adenocarcinoma of the prostate, adenocarcinoma of the rectum, carcinoid of the ileum, and leiomyoblastoma of the stomach as well as diffuse metastases from the angiosarcoma. This represents the fourth reported case of primary pulmonary angiosarcoma.

Adenocarcinoma↗
PubMed1989

[Simultaneously diagnosed triple primary neoplasms--a case report].

Reported is a case of 71-year-old man who had triple primary neoplasms that were diagnosed simultaneously on admission. He visited our hospital for examination of an abnormal mass shadow seen in the right lower lobe of his chest in a roentgenogram. That was determined as being a small cell lung cancer. We simultaneously detected that a moderately differentiated tubular gastric adenocarcinoma and an olfactory groove meningioma were overlapped as well. Attention must be paid to multiple primary neoplasms, since some of these malignancies are predicted to overlap and the percentage of overlapped neoplasms is increasing. Care must be taken to avoid mistaking an overlapped tumor for a metastatic one. In 1986, according to the Annuals of Pathological Autopsy Cases in Japan, 2196 cases that represented 9.4% of all malignancies had overlapped tumors and triple or more overlapped cases amounted to 225 a year. Malignancies in the digestive system, the respiratory system, the urinary tract and in the endocrine system seem to be greatly affected with multiple neoplasms.

Adenocarcinoma↗
PubMedDate not supplied

[Carcinoma of the breast in men, concomitant to lung neoplasm].

The authors report a case of synchronous male breast cancer and squamous cell carcinoma of the lung. Comments about etiopathogenic factors of this rare multiple primary neoplasm are made. The authors suggest that the relationship is casual, since the patient had been a heavy smoker, and the main age range for the two neoplasms in approximately the same.

Aged↗