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Nutritional programming of adult disease.

Intrauterine and early neonatal life is a period of physiological plasticity, during which environmental influences may produce long-term effects. Both undernutrition and overnutrition during this period have been shown to change disease risk in adulthood. These effects are influenced by the type, timing and duration of inappropriate nutrition and by the previous nutritional environment and may not be reflected in changes in body size. An understanding of the interaction between nutrient imbalance and alteration of gene expression is likely to be the key to optimising future health outcomes.

Animals↗

Effectiveness of a nutrition program for mothers and their anemic children under 5 years of age.

The purpose of this study was to determine the effectiveness of the Supplemental Food Program for Women, Infants, and Children (WIC) for mothers and their anemic children under 5 years of age. Sample for the study was 50 anemic children, 25 in each of two groups. The interventions (treatments) for the experimental group included individual counseling, group nutrition classes, and provision of WIC food vouchers for purchasing foods containing essential nutrients that are deficient in the diets of this high-risk population. An initial dietary assessment was done, and hemoglobin and hematocrit measurements were taken. At the end of 6 months, each participant's diet was reassessed, and hemoglobin and hematocrit measurements were again taken. Results of the study showed a 1.8 gm change in the hemoglobin measurements of the members of the experimental group and a 1.1 gm change in the hemoglobin measurements of the members of the control group.

Anemia↗

Assessment of hospital morbidity, mortality, and cost-effectiveness of a nutritional program for children under 5 years of age in Pala, Chad.

This paper analyses the effectiveness of case management at referral level for malnourished sick children in a rural district health system in the south of Chad (Pala district). The methodology followed was based on a cohort study of malnourished children as well as a cost-effective analysis of alternative options for nutritional rehabilitation strategies. Results show that effective case management at hospital level is possible with few resources as long as the nutritional rehabilitation programme is implemented on an integrated basis including early diagnosis of malnutrition for all children admitted to hospital and not to wait for a normal weight-for-height but discharge when the hospital is no longer the best place to avoid further mortality.

Case Management↗