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Effect of delivery mode on maternal-infant transmission of hepatitis B virus by immunoprophylaxis.

OBJECTIVE: To study the effect of different delivery modes on immunoprophylaxis efficacy so as to clarify whether or not cesarean section reduces immunoprophylaxis failure. METHODS: Mothers with positive hepatitis B surface antigen (HBsAg) were selected in the third trimester of pregnancy. Their babies were inoculated with hepatitis B immunoglobulin at birth and hepatitis B vaccine at 1, 2 and 7 months of age. HBsAg and its antibodies (anti-HBs) were tested at 1, 4, 7, and 12 months of age, then followed up yearly. RESULTS: A total of 301 babies entered the study, including 144 born by normal spontaneous vaginal delivery, 40 by obstetric forceps or vacuum extraction, and 117 by cesarean section. The incidence of mother's HBeAg positivity or baby's gender constitution was comparable between the three groups. There were no significant differences in the positive rate of anti-HBs or HBsAg at follow-up periods among the three groups. At 12 months of age, anti-HBs could be detected in 78.9% of the babies born by normal vaginal delivery, 84.6% of the babies by forceps or vacuum extraction, and 86.4% of the babies by cesarean section. The positive rate of HBsAg was 8.1%, 7.7%, 9.7%, and chronic HBV infection incidence was 7.3%, 7.7%, 6.8% respectively. CONCLUSIONS: There are no significant effects of delivery mode on the interruption of HBV maternal-baby transmission by immunoprophylaxis. Cesarean section does not reduce the incidence of immunoprophylaxis failure.

Cesarean Section↗

[Characteristics of the course of pregnancy in women with heart defects].

In 33 patients with different forms of the cardiac valves lesion the specificity marking the course of atriomegalia was studied on the ground of clinical, roentgenological and functional findings. Unlike non-pregnant women with similar forms of the malady here intercurrent pulmonary hypertension during gestation was ascertained, this increasing the hazard of developing edema of the lungs. The authors give preference to delivery in these patients via natural maternal passages by employing the operation with application of obstetrical forceps.

Adult↗

Retained rectal foreign bodies.

BACKGROUND: Retained rectal foreign bodies have been encountered more frequently and present a dilemma for management. Most of the reports on these cases were documented in the form of case report and from Western countries. The present study was a review on the authors' experiences in such cases. METHODS: Data from January 1979 to January 2000 were extracted from a computerized database of Taipei Veterans General Hospital. The clinical features, treatment strategies and outcomes were analyzed. RESULTS: Ten male patients (mean age: 57.0 years) with 12 presentations of retained rectal foreign bodies were collected. Glass bottles and vibrators were the most common objects encountered, while anal eroticism was reported as the reason for insertion in 50% of the cases. The majority of the objects were extracted by non-surgical methods through either anoscope (n = 4), rigid sigmoidoscope (n = 2) or colonoscope (n = 1). Obstetric forceps was utilized to remove an incarcerated bowling bottle. Emergent laparotomies were performed in cases with overt peritonitis (n = 2), pelvic sepsis (n = 1) and an impacted high-lying glass bottle. Minor complications, such as mucosal abrasion or superficial tear, were found in 62.5% of the non-surgically treated cases. Delayed bleeding was found in 2 of them. There was no mortality in our series. CONCLUSIONS: Despite its rarity, the retained rectal foreign body had varying clinical features. Most of the uncomplicated rectal foreign bodies could be simply extracted transanally under adequate anesthesia. Fiberoptic colonoscopic extraction provided an alternative choice. Open surgery should be reserved only for those patients with overt peritonitis or pelvic sepsis.

Adult↗

Guillain-Barré syndrome in pregnancy. A case report.

Severe Guillain-Barré syndrome in a patient 33 weeks pregnant, who went into premature labour 48 hours after requiring mechanical ventilation, is described. The labour required augmentation with oxytocin and a healthy 2,100 g baby was delivered using forceps. Obstetrically, the patient had an uncomplicated puerperium. She required ventilation for 20 days and after extensive physiotherapy was discharged with no disability. It is our opinion that the management of the gravid patient with Guillain-Barré syndrome does not differ much from that of non-pregnant patients with the disease. Supportive care in an intensive care unit remains the cornerstone of treatment and unnecessary obstetric intervention must be strongly resisted.

Adult↗

Patterns of obstetric procedures use in maternity care.

The use of seven obstetric procedures was studied in two institutions that use different approaches to maternity care. The study population included 796 women delivering at Booth Maternity Center and 804 women with similar sociodemographic characteristics delivering at Thomas Jefferson University Hospital during 1977 and 1978. Several differences were found between the two institutions. The majority of selected procedures were used more often at Thomas Jefferson University Hospital than at Booth Maternity Center. The greatest differences were found for women at low intrapartum risk, while differences were smallest for women at high prenatal and intrapartum risk. The two institutions differed in their use of procedures for women at various levels of prenatal and intrapartum risk. The findings suggested that most of the differences did not reflect different levels of risk in the populations served, but were due to other unidentified factors.

Adult↗

The maximin strategy in modern obstetrics.

Many currently accepted obstetrical practices exemplify a maximin strategy: making the best of the worst possible outcome, regardless of the actual probability of that outcome occurring. But a survey of recent obstetrical research fails to document superior clinical results when this strategy is employed in routine obstetrical care. Most research has studied obstetrical technologies in isolation rather than as parts of systems of interconnected interventions: this approach has tended to underestimate the risks of intervention and to overestimate the utility of a maximin strategy. Physicians practicing obstetrics should adopt a flexible approach and match the degree and type of intervention to actual patient needs. Better methods of assessing preventable prenatal risk are needed to allow identification of the rare-obstetrical patient requiring maximal intervention.

Anesthesia, Obstetrical↗

[Pregnancy and diffuse intestinal polyposis].

A follow-up of 52 pregnant women with diffuse polyps of the colon showed that gestation deteriorated the course of diffuse polyposis and provoked the appearance of the first symptoms of this disease. Diffuse polyposis had virtually no effect on the course of pregnancy and labor. Gestation eventuated in normal full-term delivery in 22 patients, in preterm delivery in 4, in 3 patients cesarean section was performed, in 1 the fetus was extracted with obstetrical forceps, 1 delivery finished with manual detachment and extraction of the placenta. Late spontaneous abortions occurred in 4 women, induced abortions were carried out in various periods in 68 women. Previous extensive resections of the colon undertaken for diffuse polyposis were not a contraindication to surgical delivery.

Colonic Polyps↗