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At least 235 records · Page 13Linked to original sources
PubMed1990

[Intracavernous indurations after injuries to the external genital parts caused by a motorcycle tank].

We have experienced 2 cases of intracavernous induration after injuries to the external genital parts caused by a motorcycle tank. Case 1. A 28-year-old male was admitted to our department complaining of painless indurations of the penile radix. Cavernosography showed segmental filling defect in left corpus cavernosum. Because erectile disturbance was noted, resection of the induration was carried out. Microscopic section of the excised tissue showed only fibrosis. Case 2. A 20-year-old male visited our clinic with chief complaints of induration of the penile radix and erectile disturbance. Corpus cavernosography demonstrated filling defect in bilateral corpus cavernosum. We recommended the resection of the indurations, but the patient refused. A brief review on etiology and therapy of intracavernous fibrosis was made.

Accidents, Traffic↗
PubMed1995

[Radical surgery and conservation of erection in Peyronie's disease].

The radical surgical option we propose for Peyronie's disease consists in removing the sclero-hyanolitic focus (plaque) and replacing it by an autologous dermal graft taken from the upper outer thigh area. Between 1981 and 1994, we operated 564 patients with Induration penis plastica (IPP), 418 of whom underwent plaque excision and dermal grafting. All could be assessed at two-year follow-up. Two main complications were observed: penile flexure relapse (71 Pts, 17% of cases), and erectile dysfunction with decreased corporal rigidity (84 Pts, 20% of cases). A mild deviation of the penis can occur some months after surgery and it is not due to disease progression (as it should have evolutive characteristics) but is mere scar retraction (44 Pts, 76% of examined relapsed flexures). The degree of this graft retraction is linked to the individual's histologic response and can be due to an idioptic tissular response or to an insufficient size of the patch. In some cases, the post-op penile flexure can result from a progression of disease (14 Pts, 24% of examined relapses flexures) and can be due either to a new "focus" or to an incomplete removal of the previous plaque. As the patient will date the onset of a possible postoperative erectile deficit from the time of the operation, it is advisable to assess preoperatively the real erectile ability of all patients. Furthermore, a post-op impaired erectile response (84 Pts, 20%) could result from a subalbuginear fibrosis of the erectile tissue that leads to a caverno-occlusive dysfunction (60%). In more than 35% of patients we found a psychogenic component, due to post-surgical stress, that involves an adrenergic hypertone with peripherical vasoconstriction. In few cases (4%) the post-op erectile dysfunction is the consequence of peroperative arterial damages that results in hypoaesthesia of the glans (injury of dorsal arteries) or in failure to obtaining corporal rigidity (damage of cavernosal arteries). A review of our experience involving plaque excision and dermal grafting led us to propose this option in case of mechanical disturbance during coitus and when the association of erectile dysfunction can be excluded.

Follow-Up Studies↗
PubMed1988

[New therapy for Peyronie's disease: superoxide dismutase by ionization. Comparison with an earlier classical series].

Due to the poor results obtained in the treatment of Peyronie's disease by ionophoresis and ultrasound, using the classical buffer solution of the cortisone thiomucase type, the authors have experimented ionophoresis with a new product: orgoteine a dismutase superoxide. Austrian authors have already demonstrated the value of this product. Its mechanism of action is still uncertain but it has an experimentally well demonstrated antiinflammatory activity. The good results are obvious not only on the pain, but also on the induration and incurvation, permitting the resumption of sexual intercourse in more than 75% of cases.

Glucuronidase↗
PubMed1979

Therapeutic use of ultrasound in urology.

After a brief historical review, experience with ultrasonic treatment is described. Since therapy performed by means of the moving head technique had beneficial effect on chronic prostatitis, plastic induration of the penis and the accompanying sexual potency disturbance, the method is recommended for use.

Chronic Disease↗
PubMed1996

Francois de LaPeyronie (1978-1747): the man and the disease he described.

The evaluation of the treatments for Peyronie's disease is difficult; the natural history is such that the plaque may resolve spontaneously [82]. In 1973, Alec Badenoch made this comment and noted that no treatment had then been evaluated in a controlled clinical study [83]. The origin of the eponym is vague and the disease remains an enigma. To this day, the treatment can be difficult. It is not surprising that so many treatments have been tried and so much dogma written. Indeed, in 1903, William Johnson Walsham, the famous surgeon from St Bartholomew's Hospital in London, and author of the standard surgical text book of the day, wrote; "... if treatment of the plaque with iodides is unsuccessful ... or if the induration progresses ... then the whole penis must be promptly amputated!' [44]. We no longer believe this dictuml.

France↗