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Results for “RHINITIS, VASOMOTOR”

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At least 235 records · Page 13Linked to original sources

PubMed1991

[Further investigation into the recurrent causes of post-vidian neurectomy and the feasibility of treating vasomotor rhinitis by surgery].

The authors had found that there were parasympathetic nerve fibres in the anterior ethmoid nerve and also cholinergic microganglia were present in the inferior turbinate of humans by the histochemical method of acetylcholinesterase (AChE). These structures had an important role in the pathogenesis of vasomotor rhinitis and also might be used to explain the recurrence of patients who had undergone vidian neurectomy. The authors put forward a new suggestion in the treatment of vasomotor rhinitis by a combination of vidian neurectomy, anterior ethmoid neurectomy and inferior turbinectomy. But the surgical method would be the last selection in the treatment of vasomotor rhinitis.

Adult↗

PubMed1985

The effect of submucosal diathermy to the inferior turbinates on nasal resistance to airflow in allergic and vasomotor rhinitis.

Twenty-one patients with nasal obstruction due to allergic or vasomotor rhinitis were assessed rhinomanometrically before and after the operation of submucosal diathermy to the inferior turbinates. It was found that the operation significantly improved the nasal airway. Most patients with an objective improvement reported a corresponding reduction in nasal obstruction. There was no tendency for patients with allergic rhinitis to be dissatisfied with the operation.

Adolescent↗

PubMedDate not supplied

[Cryosurgery for the treatment of vasomotor rhinitis].

The authors expose usefulness of the cryosurgery for the management in vasomotor rhinitis. They report the technique and patient selection, the good results attained in a high percent of cases and the lacking of complications.

Adult↗

PubMedDate not supplied

[Surgical treatment of vasomotor rhinitis].

The author recommends the cutting in the nasal septum of a window, size 2-3 X 3-4 cm, for healing severe vasomotor rhinitis, refractory to the classic O.R.L. and allergologic treatments. Of 53 patients operated this way, in 39 the vasomotor rhinitis was completely cured.

Female↗

PubMed2002

[Characteristics of autonomic dystonia in children with vasomotor rhinitis].

Data obtained at analysis of tables of screening diagnosis, cardiointervalograms, tilt tests used in examination of 57 children with neurovegetative vasomotor rhinitis point to disorders in the autonomic nervous system (by initial vegetative tone), vegetative reactivity. Parasympathetic prevalence in the initial vegetative tone and cardiointervalograms stems from sympathetic hypoactivity in the majority of the patients. The above vegetative shifts dictate the necessity of vegetotropic medication inclusion into combined therapy of vasomotor rhinitis.

Adolescent↗

PubMed1975

[Vasomotor rhinitis: a side-effect of hormonal contraception? (author's transl)].

In order to detect a possible influence of hormonal contraception on the development of vasomotor rhinitis, a five-months rhinoscopic survey was conducted on 460 women whose ages ranged from 18 to 40 years. 67 (32.7%) of the 205 women taking oral contraceptives, and 77 (30.2%) of a control group of 255 women were found to have vasomotor rhinitis. A questionaire was used in the survey, and included the following items: contraceptive preparation used, duration of use, and nasal distress associated with medication or prior pregnancies. In contrast to the findings of other authors, it was not possible to correlate the development of vasomotor rhinitis with the administration of oral contraceptives during the present study. Moreover, results were not altered by taking into account the composition of the different contraceptive drugs used. The statistical significance of the present study was established by the comparison of findings with a randomly selected control group of patients during the same period of time.

Contraceptives, Oral↗

PubMed1988

The effect of inferior turbinate outfracture on nasal resistance to airflow in vasomotor rhinitis assessed by rhinomanometry.

Twenty-eight patients with nasal obstruction due to vasomotor rhinitis were assessed using anterior rhinomanometry before and six weeks after the operation of out-fracture and amputation of the posterior ends of the inferior turbinates. It was found that the operation did not significantly improve the nasal airway. Though just over half the patients had an objective improvement in nasal airflow, only half of this group reported a subjective improvement in their symptoms.

Adolescent↗

PubMedDate not supplied

Long-term treatment with budesonide in vasomotor rhinitis.

Twelve patients entered a long-term study of budesonide treatment in vasomotor rhinitis. The efficacy of the treatment was studied. Possible systemic side effects were studied via an ACTH stimulation test prior to and during treatment. The local effect in the nasal mucosa was studied by means of a nasal biopsy before and after one year of treatment. The treatment has proved effective, while producing no systemic or local side effects during a one-year treatment period.

Administration, Topical↗

PubMed2000

[Correction of microcirculatory disorders with low-energy laser radiation in children with vasomotor rhinitis].

Turbinated bone's mucosa of 46 children aged 6 to 15 years was exposed to radiation of low-energy laser for neurovegetative vasomotor rhinitis. Repeated biomicroscopy stated that abnormal microcirculation recovered after 10 sessions of the radiation even in severe alterations of the microcirculatory bed and long history of the disease. The conclusion is made that low-energy laser radiation is effective in correction of microcirculatory disorders and tissue mechanisms of homeostasis in children with neurovegetative vasomotor rhinitis.

Adolescent↗

PubMed1990

Vasomotor rhinitis and the systemic absorption of ipratropium bromide.

Plasma concentrations of nasally administered ipratropium bromide were analyzed in 10 subjects suffering from severe vasomotor rhinitis and 10 age-sex matched control subjects. The rate of salivary secretion and heart rate were monitored in order to measure systemic anticholinergic effects. A total dose of 360 micrograms of ipratropium bromide (60 micrograms into each nostril, repeated twice at 15 min intervals) were administered nasally to the subjects in randomized order. Ipratropium bromide was rapidly absorbed from the nasal mucosa into the systemic circulation in both groups. The peak plasma concentrations were detected within 10 min after the last drug administration. The peak concentrations were about 50% higher (380 +/- 153 pg/ml) in patients than in control subjects (245 +/- 134 pg/ml). The AUCs/0-15 min (1970 +/- 1140 pg/ml X min) in patients were about 100% higher than in the control subjects (960 +/- 560 pg/ml X min). During the experiment there was a small decrease in the heart rate (8 bpm) and salivary secretion (10%) in both groups. In conclusion, the vasomotor rhinitis increases the systemic absorption of nasally administered ipratropium bromide, but the small increase in the absorption is not likely to have any clinical consequences.

Administration, Intranasal↗

PubMed1987

Control of the hypersecretion of vasomotor rhinitis by topical ipratropium bromide.

A randomized, double-blind, placebo-controlled trial of ipratropium bromide nasal spray was performed with 25 patients with vasomotor rhinitis. Criteria for selection of patients were (1) clear watery nasal discharge more than 1 hour each day, (2) absent or mild nasal obstruction, (3) no known allergic cause, and (4) no satisfactory response to previous alternative medications. Ipratropium bromide, two sprays (20 micrograms per spray) in each nasal cavity four times daily, for 3 weeks, produced a major reduction in nasal discharge severity and duration (p less than 0.00005 for daytime reduction in both). There was a decreased daily use of nasal tissues (p = 0.0017). At the end of the trial, 21 patients preferred the drug, two preferred placebo, one had no preference, and one patient dropped out for a reason unrelated to symptoms or treatment. This drug preference in favor of active medication was statistically significant at the 0.01 level. Local mild side effects were reported in 21/25 (84%) with ipratropium bromide and 8/25 (32%) with placebo (p = 0.0004). Pulse and blood pressure were not affected. In an ensuing 1-year open trial in which the frequency of use of ipratropium bromide nasal spray was selected by the subjects, the dosage chosen was considerably lower than that used in the controlled trial. There were seven dropouts caused by insufficient benefit or local side effects. Seventeen subjects continued the use of ipratropium bromide for 1 year and reported good results and no side effects. Topical nasal ipratropium bromide is highly effective in the control of the rhinorrhea of vasomotor rhinitis. Drug dosage is a major determinant of local nasal side effects.

Administration, Topical↗

PubMedDate not supplied

[Functional methods of study in the evaluation of the effectiveness of laser therapy of vasomotor rhinitis and some forms of prosopalgia].

Highly sensitive instrumental methods such as rhinopneumography, rhinorheography, rheoencephalography and segmented sphygmography were used to measure the efficacy of contact laser therapy of the pterygopalatine ganglion to treat vasomotor rhinitis and trigeminal neuralgia. This method proved efficient in the case of the nervous form of vasomotor rhinitis, Sluder syndrome, and trigeminal neuralgia. Stable remission developed in 60% of patients.

Evaluation Studies as Topic↗

PubMed1991

Treatment of 'vasomotor rhinitis' by the local application of silver nitrate.

A series of 52 patients were closely assessed prospectively to determine the effectiveness, untoward effects and patient acceptance of a new method of treatment of 'vasomotor rhinitis' by silver nitrate application. The patient's age ranged from 11 to 50 years except one who was 58 years old. The report describes the technique used and results obtained following the painting of the 'trigger area' of the nasal mucosa in patients with 'vasomotor rhinitis'. Each patient was evaluated regularly and the evaluation was based on both subjective response and clinical examination. Only cases who had rhinorrhoea and sneezing as presenting symptoms were selected. Silver nitrate (20 per cent) was used after topical anaesthesia, and patients received four applications. Successful relief was obtained in 88.5 per cent (53.0 per cent good relief; 34.6 per cent acceptable relief), while 11.5 per cent of the cases (6 out of 52 cases) had poor relief. No complication was seen among the patients during treatment and follow-up and no silver poisoning was detected.

Administration, Topical↗

PubMed2000

Autonomic nervous system evaluation of patients with vasomotor rhinitis.

OBJECTIVE: To demonstrate the utility of quantitative neurological laboratory testing of autonomic nervous system dysfunction and to apply this methodology to further study the relation of chronic vasomotor (nonallergic) rhinitis to the autonomic nervous system. METHODS: It has been suspected that vasomotor rhinitis is due either to a hyperactive parasympathetic nervous system or an imbalance between it and the sympathetic nervous system. The exact relation has not been determined. Recently neurological laboratories have been developed in which a battery of tests can be performed to determine reactivity of the autonomic nervous system. RESULTS: Autonomic nervous system testing was performed on 19 patients with symptoms fulfilling the diagnostic criteria for vasomotor rhinitis and the results were compared with 75 sex- and age-matched control subjects. Patients with vasomotor rhinitis had significant abnormalities of their sudomotor, cardiovagal, and adrenergic subscores. Their composite autonomic scale score was significantly impaired at 2.43, as compared with 0.11 for controls (P < .005). CONCLUSION: Autonomic nervous system dysfunction is significant in patients with vasomotor rhinitis. Possible factors that trigger this dysfunction including nasal trauma and extraesophageal manifestations of gastroesophageal reflux are discussed.

Adult↗

PubMedDate not supplied

The effect of ipratropium bromide on nasal hypersecretion induced by methacholine in patients with vasomotor rhinitis. A double-blind, cross-over, placebo-controlled and randomized dose-response study.

The effect of various doses of ipratropium bromide aerosol on nasal hypersecretion induced by five concentrations methacholine was studied in 24 patients with vasomotor rhinitis and excessive watery nasal secretion. The volume of nasal secretion was greater with each of the five increasing doses of methacholine from 7.5 to 120 mg/ml. The median volume of nasal secretion was alike in all patients after administration of methacholine only and after treatment by placebo followed by methacholine. When the patients were treated with ipratropium bromide prior to administering methacholine the volume of secretion was reduced significantly. With doses of 40 micrograms and 100 micrograms of ipratropium to each nostril a similar reduction in the volume of secretion occurred but a still greater reduction by the application of 200 micrograms of ipratropium when compared with treatment by the placebo. While the volume of secretion increased with each increasing concentration of methacholine, a similar pattern of reduced secretion for each concentration of methacholine was seen with each greater concentration of ipratropium. In patients with vasomotor rhinitis, treatment with ipratropium bromide was found to reduce significantly the hypersecretion induced by methacholine when compared with treatment by the placebo. This reduction was greater with greater doses of ipratropium.

Administration, Inhalation↗

PubMed2003

Ultrastructural and ultracytochemical study of the human nasal respiratory epithelium in vasomotor rhinitis.

OBJECTIVES: Several pieces of evidence have suggested that nitric oxide (NO) fulfills important functions in the respiratory mucosa, under both normal and pathological conditions. This study was performed to investigate the role of NO in the nasal respiratory epithelium of patients affected by vasomotor rhinitis. The structure and ultrastructure of the epithelium were also examined. MATERIAL AND METHODS: The localization of NO synthase activity was determined by means of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-diaphorase ultracytochemistry. Nasal mucosa was obtained from patients who had undergone surgical therapy for reduction of the inferior turbinate. RESULTS: Examination of hematoxylin-eosin-stained sections revealed that most of the nasal mucosa covering the surgical samples was characterized by severe epithelial damage. The ultrastructural study confirmed the light microscopic observations. Ciliary loss, absence of the intercellular junctions and distension of the intercellular spaces were found in the damaged epithelium. The basement membrane was frequently interrupted. Some epithelial cells were identified as basal cells. Other cells of the damaged epithelium were probably involuted ciliated and goblet cells. The ultracytochemical study showed that the basal cells were NADPH-diaphorase-negative in healthy subjects and strongly NADPH-diaphorase-positive in subjects with vasomotor rhinitis. CONCLUSIONS: It is suggested that NO has cytotoxic effects and causes inhibition of mitotic activity in the basal cells, leading to epithelial disruption and breakdown of the protective functions of the epithelium.

Adult↗

PubMed1986

[Histologic changes in the epithelium of the respiratory mucosa of the lower turbinates following argon laser strip carbonization in vasomotor rhinitis].

The histological findings after argon-ion-laser-carbonization on the respiratory mucosa of the lower turbinates in vasomotor rhinitis are described directly after laser treatment and 6 years later. The laser surgical procedure without bleeding, the reduction of swelling of the lower turbinates, a slight diminishing of secretion, a significantly better nasal ventilation are demonstrated by the histological findings. The main characteristic histological findings are: a cuneiform laser lesion extending deep into the tissue to the venous plexus, four different typical tissue layers immediately after laser treatment, centrally the carbonization zone surrounded by a coagulation zone and next to this a honeycombed zone surrounded by a very small oedematous zone. Healing of the laser lesion is always complete. First of all, a squamous epithelium with subepithelial fibrosis and hypertrophy of the muscle cells in the venous plexus are seen. Half a year after laser carbonization metaplasia of the stratified squamous epithelium into pseudostratified cylindrical ciliated epithelium is seen. Occasionally, small islands of stratified squamous epithelium are visible.

Adolescent↗

PubMed1997

Vasomotor rhinitis and sphenopalatine ganglion block.

The effectiveness of the sphenopalatine ganglion (SPG) block for the relief of symptoms in chronic vasomotor rhinitis was assessed in 30 patients of both genders. The number of blocks required for complete relief was three (range from two to four) at weekly intervals in 66.7% of volunteers. There was no recurrence of symptoms during a follow-up period of 12-20 months in 29 patients, and one patient was symptom free for 8 months. The technique is simple and can be performed as an outpatient procedure without side effects.

Adolescent↗