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Circumstances favoring jaw tumors in Burkitt's lymphoma.

In Burkitt's lymphoma, dental structures may provide the route for Epstein-Barr virus (EBV) in saliva to penetrate the jaws, thereby promoting tumor formation. In children, EBV could enter tooth sockets exposed following deciduous tooth loss and thereby contact jaw marrow lymphocytes stimulating neoplastic transformation. Marrow contact by EBV probably also occurs through carious teeth. Jaw tumors are rare in adults because their jaw marrow is no longer hematopoietic and so lacks the lymphoid substrate for the virus. In adults, jaw marrow lymphocytosis, as accompanies infectious mononucleosis and perhaps malaria, or which could develop around the roots of carious teeth having chronic periapical infection, could provide the substrate for EBV. EBV could then contact the jaw marrow lymphocytes when teeth are extracted and so favor jaw tumor development. Therefore, prevention of dental caries might reduce jaw tumor prevalence in Burkitt's lymphoma except among children ages 6-13 whose jaw marrow would unavoidably become infected by salivary EBV when the latter is present at the time of deciduous tooth loss.

Burkitt Lymphoma↗

Variation in crown and root formation and eruption of human deciduous teeth.

The aim of this study was to document variation of deciduous tooth formation and eruption. The material comprises 121 individuals of known or estimated age (using tooth length) from Spitalfields in London, and radiographs of 61 healthy living children aged 2-5 years. Other skeletal material from two medieval Scottish archaeological sites (Whithorn, N=74; Newark Bay, N=59) was also examined. Stages of crown and root formation as well as eruption (alveolar, midway, and occlusal levels) were assessed for each developing maxillary and mandibular tooth from radiographs or direct vision. Age of attainment for individual stages was calculated by probit analysis, and these data were also adapted for use in estimating age. The timing of crown completion was similar to previously reported studies, but apex completion times were later. Analysis of data relative to the first and second molars at the two stages D (crown complete) and F (root length > or =crown height) allowed comparison with the Scottish material. No significant differences were observed between population groups for tooth formation or eruption. These data fill several gaps in the literature, and will be useful in assessing maturity and predicting age during early childhood.

Age Determination by Teeth↗

The crystallinity of human deciduous teeth in hypophosphataemic vitamin D-resistant rickets.

Five teeth were obtained from three patients with hypophosphataemic vitamin D-resistant rickets (HVDRR) and five corresponding sound teeth from five healthy children. According to powder X-ray diffraction analysis, the half-peak breadths of (310) and (002) reflections of HVDRR dentine were smaller than those of normal dentine. Splitting fractions obtained from i.r. spectral analysis of HVDRR dentine powder were larger than those of normal. Microbeam X-ray diffraction analysis showed that the relative half-peak breadths of globular dentine in ground sections of HVDRR teeth were smaller than those of normal circumpulpal dentine. Transmission electron microscopy demonstrated that the hydroxyapatite crystals of globular dentine in HVDRR teeth were larger than those of normal dentine. Thus the crystallinity of deciduous tooth dentine in HVDRR was greater than that of normal dentine, mainly because of the large hydroxyapatite crystals in HVDRR globular dentine.

Child↗

Morphology of the deciduous tusk (tush) of the African elephant (Loxodonta africana).

The tusk of the African elephant is preceded by a deciduous tooth generally known as the tush. Tushes from nine elephant fetuses and six calves younger than 1 year were exposed by dissection and described morphologically. All tushes consisted of a crown, root and pulpal cavity, the formation of which is completed soon after birth. They reached a maximum length of 5 cm, appeared not to erupt through the skin and were pushed aside and resorbed during enlargement of the distally located primordium of the tusk. Dental enamel, which covered the crown, could easily be removed and consisted of rods with an interwoven arrangement; the dentine-enamel junction was flat. Cellular cementum extended for variable distances over the crown and the dentine was tubular in nature. Although the tush apparently has no function, it provides the anlage and orientation for the development of its permanent successor.

Animals↗

Fetal alcohol syndrome.

A case of fetal alcohol syndrome in an 8-month-old infant is presented. Several of the maxillofacial anomalies associated with this syndrome were present. In addition, a large dentigerous cyst was found, a rare lesion occurring with a deciduous tooth and never before reported in association with fetal alcohol syndrome.

Dentigerous Cyst↗

Prediction models for 90Sr in shed deciduous teeth and infant bone.

Shed deciduous teeth were collected in 1966-69 in Denmark, the Faroes and Greenland from children born in the period 1953-63. 235 samples of crowns were analysed for 90Sr. The 90Sr levels in deciduous tooth crowns were related to the fall-out rate and the accumulated fall-out. The tooth levels in children born in 1950-62 could be described with the same equation as the 90Sr bone levels in 1-yr-old infants born in 1962-68. The prediction models for 90Sr in teeth and bones showed that for given amount of fall-out the Faroese levels became nearly twice as high as the Danish. The maximum teeth and bone levels were found in children born in 1963, where the Faroese level was estimated from the prediction model to be 24 pCi 90Sr/g Ca.

Bone and Bones↗

Mineralized nodule formation by human dental papilla cells in culture.

Human dental papilla cells were enzymatically separated from deciduous tooth germs of an 8-month-old embryo legally aborted. The second passage cells were cultured up to 35 days in 3 groups. The beta-GP group was cultured in the Dulbecco MEM containing ascorbic acid and beta-glycerophosphate supplemented with 15% fetal bovine serum. The Dex group was in the same medium, in addition containing dexamethasone. The control group contained none of the 3 chemicals. Mineralized nodules were formed after 15 days in the beta-GP and Dex groups. Only in the presence of ascorbic acid and organic phosphate did they mineralize. The addition of dexamethasone caused a significant increase in the number of nodules. By electron microscopy, the nodules contained needle-shaped crystals associated with a network of collagen fibrils. Calcium and phosphorus were detected by energy-dispersive X-ray microanalysis in the nodules. Furthermore, the crystalline material exhibited a pattern consistent with hydroxyapatite and dentin when examined by X-ray diffractometry. Cells showed high levels of alkaline phosphatase activity, which was increased 2-3 times in the presence of the 3 chemicals. These results indicated that human dental papilla cells have the ability to form dentin in culture. The formation of mineralized nodules by human dental papilla in vitro provides a useful model for studying the morphogenesis and differentiation of dental papilla ectomesenchyme.

Alkaline Phosphatase↗

Enamel hypoplasia of a maxillary central incisor.

This article describes a case of a permanent central incisor with enamel hypoplasia. A 7-year-old patient had suffered an injury in a car accident when she was 2 1/2 years old. The maxillary right central deciduous incisor was lost in the accident. At the time of examination a fistula was present buccally to the maxillary right permanent incisor, which had erupted only 3 mm into the mouth. The maxillary left central incisor had erupted fully. After clinical and radiographic examination the lost deciduous incisor was found in the bone buccally to the permanent incisor. The deciduous tooth was extracted surgically, the fistula healed and the gingiva became normal. The permanent incisor had a 3-mm-wide zone of hypoplastic enamel on the buccal surface of the crown.

Child↗

Ion probe analysis of discolored areas in the enamel of deciduous teeth.

Discolored and normal areas in the enamel of eleven primary teeth from children born to diabetic mothers were analysed with ion probe technique. These teeth were compared with four teeth from children born to healthy mothers. Fourteen different mass numbers were recorded. The affected areas showed a proportionally higher content of organic material, but the differences in recorded values reached statistical significance only in the postnatal enamel. The study revealed a considerable biological variation in the chemical composition of deciduous tooth enamel. The brown areas may be partly related to variation in physical properties.

Child↗

Mineral trioxide aggregate as a pulpotomy agent in primary molars: an in vivo study.

The retention of pulpally involved deciduous tooth in a healthy state until the time of normal exfoliation remains to be one of the challenges for Pedodontists. A scientific noise has been generated about several materials some of which have been popular pulpotomy medicaments. Concerns have been raised about the toxicity and potential carcinogenicity of these materials, and alternatives have been proposed to maintain the partial pulp vitality, however to date no material has been accepted as an ideal pulpotomy agent. Mineral trioxide aggregate (MTA) is a biocompatible material which provides a biological seal. MTA has been proposed as a potential medicament for various pulpal procedures like pulp capping with reversible pulpitis, apexification, repair of root perforations, etc. Hence the present study was done to evaluate the efficacy of MTA as a pulpotomy medicament. A clinical and radiographic evaluation was done on children where MTA was used as pulpotomy medicament in primary molars for a period of 6 months and it was found to be a successful material.

Aluminum Compounds↗

[Root fragments of deciduous teeth remaining in the alveolar bone. Microradiographic and ultrastructural study].

Deciduous tooth fragments retained in the alveolar bone can be either unresorbed portions of root, or root splinters of various sizes resulting from a fracture. The composition and ultrastructure of the fragment dentine remain unchanged even after a long period of inclusion; any specific alterations present at the time of inclusion persist. Some fracture surfaces and resorption lacunae of completely embedded fragments are covered with newly-formed cementum, usually in continuity with the preexisting cementum. Osteo-dentinal ankylosis occurs on certain resorption surfaces. The ultrastructure of the ankylosis zones is characterized by the continuity of the collagenous fibrillar framework of the dentine and that of the newly-formed bone, and by the penetration of bone substance into the dentinal tubuli and the pulp canals.

Adolescent↗

[Traumatic injuries of deciduous teeth].

Review of literature regarding frequency of traumatic injuries of primary teeth, types of injuries, therapy and possible consequences in permanent dentition. The diagram of prevalence shows no direct correlation to age, whereas according to diagram of incidence 70% of injuries occur in the second and third years of life. Injuries without dislocation of the deciduous tooth: fractura coronae dentis decidui, contusio seu concussio dentis decidui, fractura radicis decidui. Injuries with dislocation: luxatio totalis dentis decidui, luxatio partialis dentis decidui, intrusio dentis decidui. Consequences of traumas can be detected in disturbances of second dentition, in developmental anomalies of enamel and in considerable deformities of homologous permanent tooth.

Age Distribution↗

The interrelation between the number of deciduous teeth and the morphological maturity of a child.

The process of the first dentition is part of a very short period during human development characterised by an extraordinary intensity of growth processes. The main purpose of the present study is to provide information on the relationship between three criteria of biological maturity of children: body height, body weight and the number of milk teeth. The present study is based on a cross-sectional material collected in 30 nurseries in Łódź (Poland). The analysis was carried out on 1901 children (981 boys and 920 girls) aged from 2 to 36 months. All coefficients of Pearson correlation and partial correlations between the analysed variables are statistically significant at the 0.01 level. The highest value of coefficient correlation was noticed for the relation between dental and chronological age, as well as between dental and morphological age based on body height (about 0.90 and 0.85, respectively). Through an analysis of regression (backward) equations for predicting the number of teeth from chronological age, body weight and body height were calculated. These mathematical equations were confirmed in practice in about 80% of the children. Coefficients of determinations between the analysed variables are high for boys and girls (about 72% and 74%, respectively). This observations demonstrate conclusively that there exists a highly significant relation between deciduous tooth age and morphological age.

Age Determination by Teeth↗

[Bonding and primary teeth].

The aim of this publication is to study the bonding on the aprismatic outer layer of the deciduous enamel. To enhance the adhesion, the deciduous tooth surfaces were etched for 60s and the resin modified glass ionomer cement Fuji Ortho LC was selected instead of a conventional composite material. The author shows several examples of bonding during the orthopedic phase, the orthodontic phase and during retention.

Acrylic Resins↗

[The study of the activities of salivary proteolytic enzymes in children].

OBJECTIVE: The activities of proteolytic enzymes in saliva were assayed to determine whether they were related to caries sensitivity and gender in the children. METHODS: Fluorometric and photometric methods were applied. Three enzymes included leucine amino peptidase, dipeptidyl peptidase IV and trypsin-like proteinase. RESULTS: 1. Only dipeptidyl peptidase IV and trypsin-like proteinase were demonstrated in saliva, they were obviously lower than those in dental plaque (P < 0.05); 2. The activities of proteolytic enzymes of male and female children as well as caries-active and caries-free children showed no difference. CONCLUSION: Proteolytic enzymes play little role in caries formation of deciduous tooth.

Child↗

Emergence of deciduous teeth in Punjabi children, north India.

Data on deciduous tooth emergence of 312 children aged 4 to 31 months of Punjabi parentage are presented. Probit analysis was used to derive the median age of tooth emergence. Female children are found to be advanced with respect to tooth emergence than their male counterparts. While comparing the present data with those from other populations it is found that, in general, the mean number of emerged teeth in Punjabi children is more at most ages, with lower median age of eruption for most teeth. Magnitude of interage variability in the eruption times is noticed to be maximum in the 16-17 and 20-21 months age groups. The findings of the study suggest that number of teeth can be used as a parameter for the estimation of age.

Age Factors↗

Coronally positioned flap with subepithelial connective tissue graft for root coverage: various indications and flap designs.

Aesthetic concerns and functional abnormalities, such as dentin hypersensitivity, are often associated with gingival recession defects. Root coverage procedures aim to restore both gingival aesthetics and function in recession defects. The coronally positioned flap combined with the subepithelial connective tissue graft is one of the most widely used root coverage procedures. The present report illustrates four different indications where this procedure has been successfully employed. An isolated Miller class II recession defect associated with frenum pull, multiple adjacent Miller class I defects in the aesthetic zone, an isolated Miller class I defect associated with dentin hypersensitivity, and an isolated Miller class II defect on a retained deciduous tooth are the four diverse conditions treated by periodontal plastic surgery. Different approaches were used to create the coronally positioned flap. Treatment resulted in complete root coverage, resolution of hypersensitivity, and satisfaction of the patients' aesthetic concerns. An effective and predictable treatment modality, such as the coronally positioned flap combined with the subepithelial connective tissue graft, should be considered when treatment planning for gingival recession defects.

Adult↗