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PubMed2002

Treatment of ruptured anterior circulation aneurysm based on computerized tomography angiography: surgical results and indications for additional digital subtraction angiography.

The purpose of this study is to determine whether or to what extent computerized tomography angiography (CTA) can replace digital subtraction angiography (DSA) for ruptured anterior circulation cerebral aneurysms. We reviewed our patients in two different periods and evaluated in what cases we should perform additional DSA. In the first period, both CTA and DSA were routinely performed except on patients that were suitable for emergent surgery with CTA only. In the second period, only CTA was performed routinely as a preoperative workup and if further information was necessary, additional DSA was performed. A total of 106 (52 in the first period and 54 in the second period) patients were included. Characteristics of the patients and outcome at three months were similar in the two periods. In the second period, ten patients underwent additional DSA. Our results suggest that most of cases with ruptured anterior circulation aneurysms can be successfully treated on the basis of CTA alone.

Adult↗
PubMedDate not supplied

Subtracted 3D CT angiography for evaluation of internal carotid artery aneurysms: comparison with conventional digital subtraction angiography.

BACKGROUND AND PURPOSE: 3D computed tomographic angiography (3DCTA) has been used recently for the evaluation of intracerebral aneurysms, but it is difficult to use this technique to visualize aneurysms near the base of the skull because of the presence of bone. Subtracted 3DCTA could replace digital subtraction angiography (DSA) for evaluation of aneurysms near the base of the skull if the 2 methods were to give similar results. The aim of this study was to compare the evaluation of aneurysms of the internal carotid artery (ICA) near the base of the skull by subtracted 3DCTA and DSA. METHODS: CTA and DSA were obtained in 25 patients with unruptured aneurysms of the ICA. To create subtracted 3DCTA images, we used a volume subtraction (VS) method, wherein nonenhanced volume data are subtracted from enhanced volume data. CTA and DSA were reviewed by 2 neuroradiologists who performed the detection and characterization of aneurysms of the ICA by using 2D multiplanar reformatted (MPR) and VS- and nonsubtracted (NS)-3DCTA images with volume rendering techniques. RESULTS: DSA detected 29 aneurysms in the 25 patients. VS-3DCTA detected all 29 aneurysms in the 25 patients and was equivalent to DSA for evaluating their characteristics (location, size, and direction). NS-3DCTA detected 19 (1 cavernous, 4 ophthalmic, 1 superior hypophyseal, 7 posterior communicating, and 6 anterior choroidal artery) of these 29 aneurysms, but it could not characterize ophthalmic and superior hypophyseal artery aneurysms because they were only partly visible on NS-3DCTA because of bony structures. 2D-MPR images detected all but the small aneurysms (24 of 29 detected). VS-3DCTA and 2D-MPR could visualize all branching arteries (ophthalmic, posterior communicating, and anterior choroidal) detected by DSA, but NS-3DCTA could not visualize ophthalmic arteries because of the presence of bony structures. CONCLUSION: VS-3DCTA can be used as an alternative to DSA for preoperative examination of aneurysms near the skull base, where it provides equivalent identification and characterization.

Adult↗
PubMed1983

[Digital subtraction angiography in ischemic cerebrovascular accidents].

Recent advances in computer and radiological technology have permitted reassessment of intravenous angiography in the evaluation of cerebrovascular disorders. Although digital subtraction angiography is a relatively new technique, it has rapidly gained a widespread acceptance. It has extended the use of angiography to outpatients and to people in whom conventional angiography is contraindicated. This reliable, safe, and relatively noninvasive technique offers the user two benefits: real-time subtraction and enhanced image quality. The system allows angiographic evaluation of the extracranial and intracranial vessels by means of intravenous injection of contrast material. Extracranial studies clearly demonstrate stenoses and occlusions of the major cervicocephalic arteries. Intracranial studies usually detect major cerebrovascular occlusions and provide insight into the collateral flow patterns. Intravenous digital subtraction angiography permits accurate assessment of cervicocephalic vessels after surgical repair. Although intravenous digital subtraction angiography obviates the need for conventional angiography in many cases, movements from the patients, or superimposition of vascular structures can substantially degrade the quality of the images. Digital subtraction angiography with intra-arterial injection of contrast medium will be contemplated in patients with poor intravenous digital subtraction angiography studies prior to surgery.

Cerebral Angiography↗
PubMed1981

Digital subtraction angiography of the carotid arteries: a comparative study in 100 patients.

Conventional angiography and intravenous digital subtraction angiography (DSA) were used to examine the common carotid artery bifurcations in 100 patients with clinically suspected arteriosclerotic disease. In 60% of the patients, the quality of the DSA examination was good or excellent bilaterally; in 23%, the quality was good or excellent on one side; in the remaining 17%, both bifurcations were poorly visualized. There was excellent correlation of conventional and digital angiograms when the carotid bifurcations were well visualized with DSA (sensitivity 95%, specificity 99%, accuracy 97%). When the carotid bifurcations were not well visualized with DSA, there was a substantial chance for misinterpretation of the study (sensitivity 54%, specificity 70%, accuracy 64%). Digital subtraction angiography is a safe, rapid procedure that can be performed on an outpatient basis and can accurately evaluate the carotid bifurcation in approximately 70% of the arteries examined.

Adult↗
PubMed1996

MR angiography with three-dimensional MR digital subtraction angiography.

We have developed a time-resolved, contrast-enhanced, volume-imaging technique for magnetic resonance (MR) angiography, known as three-dimensional (3D) MR digital subtraction angiography (DSA). This technique greatly improves MR angiogram quality because it combines the injection of a contrast agent with the ability to image the temporal passage of this agent and, thereby, obviates the need for timing scans or other complicated synchronization schemes. Three-dimensional MR DSA also represents a potential improvement in the sense that, relative to DSA and computed tomography (CT) angiography, the contrast agent is less toxic. Additionally, unlike CT angiography, images may be acquired during the passage of the contrast agent. Therefore, 3D MR DSA shows the sequential passage of contrast through the arterial and venous system, followed by uptake in various organs. Unlike conventional DSA, 3D MR DSA imaging acquires full volume datasets, which allows subsequent reprojection and reformatting. Because images are obtained at approximately 2-6 s time intervals using a temporal aperture on the order of several seconds, motion (such as respiration) causes only a temporary disruption of image quality, similar to that observed in MR fluoroscopy. These temporal characteristics also make the proposed sequence insensitive to variations in the shape and timing of the contrast-pass curve. Although the individual time-resolved images will have somewhat decreased signal-to-noise ratio (SNR) relative to nontime-resolved scans collected in the same acquisition time, the SNR improvement due to the gadolinium appears to accommodate this trade-off. Additionally, if motion between successive images is small, then the full suite of temporal processing schemes, previously investigated in connection with DSA and time-resolved two-dimensional (2D) MR, such as mask mode subtraction, simple matched filtering and Eigen filtering, can be used to obtain composite images. These derived images generally have an increased SNR or negligible venous signal if an arterial-phase image is not obtained in the early time-resolved images. In summary, 3D MR DSA will significantly advance MR angiography because of the following intrinsic advantages: (1) improved signal-to-noise, (2) scan orientation may be chosen independently of the direction of blood flow, (3) uniform vascular signal, even from regions of complex flow, (4) minimization of motion artifacts, (5) greatly reduced sensitivity to variation in the shape and timing of the contrast bolus, (6) ability to be reformatted or reprojected, and (7) ability to apply a variety of temporal postprocessing techniques.

Angiography, Digital Subtraction↗
PubMed1993

Diagnosis and follow-up of small hepatocellular carcinoma with selective intraarterial digital subtraction angiography.

To clarify the angiographic features of small hepatocellular carcinoma, we performed digital subtraction angiography in 91 patients with hepatocellular carcinomas of 2 cm or less. Repeated digital subtraction angiography studies were performed in 25 patients whose first angiograms showed no tumor staining. Digital subtraction angiography showed hypervascular tumor staining in only 51 patients (56.0%). We found that the smaller a tumor nodule was, the lower the detection rate of tumor stain on digital subtraction angiography. The detection rate of hypervascularity was closely correlated with the grading of histological differentiation of the tumors: well-differentiated hepatocellular carcinomas more often showed negative tumor staining. Repeated digital subtraction angiography studies showed alteration of tumor staining from isovascular to hypervascular in 6 of 6 patients with tumors that became larger than 2 cm and in 12 of 19 patients with tumors that remained 2 cm or smaller. Conversion of vascularity is commonly found in the early stage of small hepatocellular carcinoma, and the process is usually slow, taking approximately 1 yr.

Adult↗
PubMed1982

Digital subtraction angiography for localization of parathyroid lesions.

Transvenous digital subtraction angiography was used before surgery to evaluate seven patients with chemical evidence of hyperparathyroidism. Digital subtraction angiography identified parathyroid adenomas in six of the seven patients. This technique is a sensitive, although not specific, method to identify small vascular tumors.

Adenoma↗
PubMed1982

The use of digital subtraction angiography in the evaluation of carotid cavernous sinus fistulas.

Intravenous digital subtraction angiography (IV-DSA) is a safe, rapid procedure that can be performed on an outpatient basis and provide diagnostic information comparable to conventional angiography. This paper reviews the initial experience with intravenous digital subtraction angiography in the evaluation of five cases of carotid cavernous sinus fistula, digital subtraction angiography.

Angiography↗
PubMed1993

Emergent aneurysmal surgery without preoperative angiography: usefulness of the intraoperative portable digital subtraction angiography.

A 42-year-old male with subarachnoid and large intracerebral hemorrhage in coma was operated without preoperative angiography because of impending cerebral herniation. After emergent decompressive craniotomy, intraoperative digital subtraction angiography (DSA) was performed and a middle cerebral artery aneurysm was demonstrated clearly. Aneurysmal neck clipping was successfully performed, and the patient made a good recovery and returned to almost independent activity with minimal hemiparesis. The prognosis of patients with ruptured aneurysm with large intracerebral hematoma is affected by early hematoma evacuation. Since the time spent for preoperative angiography may cause irreversible damage to the brain stem, in such case, early decompressive procedure and subsequent aneurysm diagnosis by intraoperative DSA may be used as alternative method to achieve a good outcome.

Adult↗
PubMedDate not supplied

Failing hemodialysis arteriovenous fistula and percutaneous treatment: imaging with CT, MRI and digital subtraction angiography.

PURPOSE: To evaluate failing hemodialysis arteriovenous fistulas with helical CT angiography (CTA), MR angiography (MRA), and digital subtraction angiography (DSA), and to compare the efficacy of the three techniques in detecting the number, location, grade, and extent of stenoses and in assessing the technical results of percutaneous transluminal angioplasty (PTA) and stenting. METHODS: Thirteen patients with Brescia-Cimino arteriovenous fistula malfunction underwent MRA and CTA of the fistula and, within 1 week, DSA. A total of 11 PTAs were performed; in three cases an MR-compatible stent was placed. DSA served as the gold standard for comparison in all patients. The presence, site, and number of stenoses or occlusions and the technical results of percutaneous procedures were assessed with DSA, CTA, and MRA. RESULTS: MRA underestimated a single stenosis in one patient; CTA and MRA did not overestimate any stenosis. Significant artifacts related to stent geometry and/or underlying metal were seen in MRA sequences in two cases. CONCLUSIONS: CT and MRI can provide information regarding the degree of vascular impairment, helping to stratify patients into those who can have PTA (single or multiple stenoses) versus those who require an operative procedure (occlusion). Conventional angiography can be reserved for candidates for percutaneous intervention.

Aged↗
PubMed1999

Evaluation of cerebral aneurysms with high-resolution MR angiography using a section-interpolation technique: correlation with digital subtraction angiography.

BACKGROUND AND PURPOSE: The objective was to evaluate the results of high-resolution, fast-speed, section-interpolation MR angiography and digital subtraction angiography (DSA), thereby examining the potential use of a primary noninvasive screening test for intracranial aneurysms. METHODS: The images were obtained in 39 cerebral aneurysmal lesions from 30 patients with a time-of-flight MR angiographic technique using a 1.5-T superconducting MR system. The total image volume was divided into four slabs, with 48 partitions each. To save time, only 24 phase-encoded steps were measured and interpolated to 48. The parameters used included 30/6.4 (TR/TE), a flip angle of 25 degrees , a 160x512 matrix, a field of view of 150x200, 7 minutes 42 seconds of scan time, an effective thickness of 0.7 mm, and an entire thickness of 102.2 mm. Maximum intensity projection was used for the image analysis, and a multiplanar reconstruction technique was used for patients with intracranial aneurysms. RESULTS: Among 39 intracranial aneurysmal lesions in 30 patients, 21 were ruptured and 18 were unruptured. Twelve lesions were less than 2 mm in size, 12 were 3 to 5 mm, 12 were 6 to 9 mm, and three were larger than 10 mm. At initial examinations, 38 of 39 aneurysmal lesions were detected by both MR angiography and DSA, with 97% sensitivity. In confirming aneurysms in neck and parent vessels, multiplanar reconstruction was successful in detecting all 39 aneurysms, whereas MR angiography was successful in detecting 27 (69%) and DSA was successful in detecting 32 (82%) of the lesions. CONCLUSION: High-resolution MR angiography with a section-interpolation technique showed equal results to those of DSA for the detection of intracranial aneurysms and may be used as a primary noninvasive screening test. In the evaluation of aneurysms in neck and parent vessels, the concurrent use of MR angiography and multiplanar reconstruction was far superior to the use of either MR angiography or DSA alone.

Adult↗
PubMed1984

Digital subtraction angiography in staging renal cell carcinoma: comparison with computerized tomography and histopathology.

Digital subtraction angiography was compared to computerized tomography and histopathological findings for staging renal cell carcinoma in 24 patients. Injection of contrast material through a 16 gauge angiocatheter into the femoral vein provided digital subtraction cavography, digital subtraction arteriography and excretory urography during 1 investigation. Computerized tomography established the diagnosis in all patients, while digital subtraction angiography showed all angiographic signs of renal cell carcinoma in 14 (58 per cent). T staging was correct on computerized tomography in 18 patients and on digital subtraction angiography in 16. Absence or presence of venous involvement was indicated correctly by computerized tomography in 20 patients and by digital subtraction angiography in 21. In small tumors the combination of ultrasonography, digital subtraction angiography and excretory urography is sufficient for an operation. In all other tumors digital subtraction angiography cannot replace computerized tomography but adds useful information about arterial distribution, possible venous tumor thrombus and the anatomical relationship of vessels.

Angiography↗
PubMedDate not supplied

Importance of digital subtraction angiography in the imaging of locomotor tumors.

Digital subtraction angiography (DSA) performed with modern sophisticated equipment has been improved substantially in its ability to document also small vessels and pathologic vascularization patterns in tumorous conditions of the locomotor apparatus. Its domain is in imaging vascular patterns hidden by structural (mainly sclerotic) shadows in their vicinity. In 152 patients out of the total patient collective in the Bone Tumor Register in Prague having a bone tumor or a tumor-like condition, DSA proved to be a mild method of choice for the diagnostic imaging of vascular patterns of the lesions and/or combined diapeutic interventions and has not lost its raison d'être in the era of CT and MRI.

Angiography, Digital Subtraction↗
PubMed2006

Radiation doses to patients from digital subtraction angiography.

This investigation determined patient doses during digital subtraction angiography (DSA). Fluoroscopy time, dose-area product (DAP) and entrance surface air kerma (ESAK) were analysed from 263 DSA examinations, classified into seven categories: (1) abdominal aorta, iliac, femoral, popliteal and leg arteries; (2) abdominal aorta and superselective DSA of renal arteries; (3) combination of (1) and (2); (4) superselective DSA of common carotid and vertebral arteries, intracranial branches in face and profile projections; (5) superselective DSA of hepatic, splenic, superior and inferior mesenteric arteries; (6) combination of (1) and (4); and (7) celiac trunk and branches. Median DAP values were 67.7, 92.9, 76.6, 53.6, 105.7, 76.1 and 2.6 Gy cm2, respectively. With the exception of one examination, ESAK values were below 2 Gy: the limit for erythema. Compared with published data, DAP values were within the range reported for (1) and (4), slightly larger for (2) and (5), whereas no references were identified for the remaining three categories.

Air↗
PubMed1991

An evaluation of intravenous digital subtraction angiography in assessing lower limb ischaemia.

Intravenous digital subtraction angiography (IV DSA) is a relatively simple, minimally invasive technique which can be performed on an out-patient basis. On the other hand it lacks the clarity and definition of conventional angiography (CA). This paper evaluates the usefulness of IV DSA in planning intervention in lower limb ischaemia. Between January 1988 and June 1989, 492 IV DSAs were performed on patients with peripheral vascular disease. The results of the DSA were compatible with the clinical impression in 480 cases and management was planned accordingly. In 12 (2.4%) the DSA was inconclusive (failure to confirm clinical findings in three, insufficient information in six, technical failure in three), and CA was performed. This resulted in six patients having an arterial reconstruction who would not otherwise have done so. One hundred and six of the 480 cases routinely had a CA, in addition to the IV DSA prior to planned angioplasty or intra-arterial thrombolysis. These provided a direct comparison between the two techniques. In 99 (93%) the findings of the two procedures were identical. Significant lesions (not seen on DSA) were identified by CA in four patients, (false: -ve 3.8%) two of which were successfully dealt with by angioplasty. In two patients lesions were not confirmed (false: +ve 1.9%) and in one, disease progression was noted. Thus of the 106 patients, two (1.9%) were found to have lesions on CA, but not on IV DSA, which were successfully treated. IV DSA is satisfactory in most patients with lower limb ischaemia. Its imperfections are more than outweighed by its simplicity and patient acceptability.

Aged↗