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PubMed2006

Ethics and pharmaceutical medicine -- the full report of the Ethical Issues Committee of the Faculty of Pharmaceutical Medicine of the Royal Colleges of Physicians of the UK.

The practice of pharmaceutical medicine brings with it ethical challenges and dilemmas often very different from those encountered in the practice of clinical medicine. Having established a framework of guiding ethical principles, this report aims to look in some detail at specific areas of possible ethical concern to pharmaceutical physicians, offering practical advice and guidance on good practice. The report covers issues related to pharmaceutical research, including dissemination of research findings, communication with other health professionals and patients and involvement of pharmaceutical physicians and companies in the provision of patient services. The primacy of the interests of patients and the wider public is emphasised, and the possible impact of new developments in pharmaceutical technology is explored. It is hoped that the report will help those working in pharmaceutical medicine and act as a stimulus for wider discussion and debate.

Biomedical Research↗
PubMed2006

Guiding Principles for Pharmaceutical Physicians from the Ethical Issues Committee of the Faculty of Pharmaceutical Medicine of the Royal Colleges of Physicians of the UK.

Medical practitioners practising in the field of pharmaceutical medicine, whether in industry, regulatory bodies or an academic environment, are bound by the same ethical standards which apply to all doctors. Their work, however, leads to some very specific ethical considerations which may not be fully explored in ethical codes based in clinical medicine. This document aims to establish some guiding principles which should underpin a working ethical framework for pharmaceutical physicians. It clearly places the protection of patients (and research subjects) and the doctor's duties to wider society ahead of responsibilities to an individual employer while emphasising the importance of adherence to high standards of research, including dissemination of findings. These principles form the basis of a fuller report which offers more specific practical advice on possible ethical conflicts or dilemmas.

Clinical Trials as Topic↗
PubMed1989

Guidelines for the use of dietary fluoride supplements in Australia.

A survey in 1988 of brands of fluoride supplements available in a non-fluoridated town in Western Australia, and tablets described in pharmaceutical product registers, revealed that six brands of tablets and one brand of solution (drops) were on the market. Tablets contained 2.2 mg or 1.1 mg NaF; the solution contained 2.2 mg NaF per mL. All products provided age-dose schedules which would give fluoride supplementation at levels greater than the National Health and Medical Research Council guidelines. In one case, infants following the schedule would receive four times the recommended dose for the first two years of life. Compliance with several of the age-dose schedules would be certain to cause significant dental fluorosis. Whether the others caused fluorosis would depend on the quantity of fluoride in the diet, and consumption of fluoride toothpaste. The survey showed a generalized disregard on the part of the ethical pharmaceutical industry for the risk of dental fluorosis, and reveals a need for a voluntary, or legally enforced, code of conduct for manufacturers of fluoride supplements. The value of guidelines which are not monitored is doubtful.

Australia↗