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Results for “Granuloma, Pyogenic”

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PubMed2006

Multiple periungual pyogenic granulomas following systemic 5-fluorouracil.

A 65-year-old man presented with a 7-month history of eight bleeding periungual lesions on both feet. The clinical diagnosis of multiple pyogenic granulomas was confirmed by histological examination. Historically, the pyogenic granulomas appeared 3 months after commencing 5-fluorouracil chemotherapy for rectal carcinoma, suggesting a possible causative relationship. Chemotherapy was ceased by the supervising oncologist. Resolution occurred after two lesions had been treated with curettage and diathermy, and the remaining lesions with occlusive dressings over Kenacomb ointment (triamcinolone acetonide 0.1%, neomycin sulphate 0.25%, gramicidin 0.025%, nystatin 100,000 U/g) topically twice daily for a period of 3 months.

Adenocarcinoma↗

PubMed2003

Suburethral vaginal erosion and pyogenic granuloma formation: an unusual complication of intravaginal slingplasty (IVS).

We report an unusual case of suburethral vaginal erosion and pyogenic granuloma formation 14 months after intravaginal slingplasty (IVS). A 64-year-old woman underwent IVS for recurrent stress incontinence 12 years after Burch colposuspension. Following seemingly uncomplicated surgery and recovery, she developed a recurrent urinary tract infection which was treated with antibiotics. When she presented with vaginal pain and postmenopausal bleeding approximately 14 months postoperatively, she was found to have suburethral vaginal erosion of the tape and a pyogenic granuloma. The exposed tape was removed, the granuloma excised, and the overlying vaginal skin was then closed. She then made an uneventful recovery.

Female↗

PubMed1980

The abnormal dermis in pyogenic granuloma. Histochemical and ultrastructural observations.

The connective and vascular tissues of pyogenic granulomas have been studied in lesions from forty-six patients. Twenty were studied histochemically, and five were examined ultrastructurally. Both tissues showed a wide range of maturity and cellular activity. The fibroblasts in particular showed evidence of increased synthetic activity. Intranuclear inclusion bodies, suggestive of altered synthetic activity, were found in the endothelial cells of four lesions. It is suggested that pyogenic granuloma arises from disordered growth of papillary dermis.

Connective Tissue↗

PubMed1979

Intravenous pyogenic granuloma. A study of 18 cases.

A series of 18 intravenous pyogenic granulomas (IVPG) was studied. The lesions were limited to the neck and upper extremity and appeared as nonspecific tumors. Most had a clinical duration of 2 months or less. Treatment was by excision and there were no recurrences. IVPG consists of an intraluminal polyp attached to the wall of the vein by a fibrovascular stalk. The characteristic appearance is of lobules of capillaries separated by a fibromyxoid stroma. The organization and histologic detail are similar to those of pyogenic granulomas that are uncomplicated by the changes of inflammation. Our observations suggest that IVPG develops in or adjacent to the wall of the involved vein. It probably receives its blood supply from a small artery that enters the lesion in the region of the stalk.

Adolescent↗

PubMed2003

Metastatic hepatocellular carcinoma of gingiva mimicking pyogenic granuloma.

We report a case of metastatic hepatocellular carcinoma of gingiva mimicking pyogenic granuloma. To our knowledge, no such reports have been published in the literature of dermatology. Gingival metastatic lesions are of interest both because they are easily mistaken for several benign lesions and because they may be the first sign of an undiscovered malignancy.

Aged↗

PubMed1985

Intravenous pyogenic granuloma of the ocular adnexa. Report of two cases and review of the literature.

Intravenous pyogenic granuloma is a recently described form of pyogenic granuloma (PG) in which the angiomatous proliferation is confined entirely within the lumen of a vein. To our knowledge, only four cases involving the ocular adnexa, including two that we encountered, have been described. Histologically, this benign lesion is similar to PG of other locations and is characterized by lobular congeries of capillaries embedded in a fibromyxoid matrix containing scattered chronic inflammatory cells. The whole lesion appears as a single polypoid mass projecting into the lumen of a dilated vein. The histogenesis of this lesion remains obscure. Complete local excision is the treatment of choice. Intravenous PG can be differentiated from other intravascular fibroangiomatous proliferations, including intravascular papillary endothelial hyperplasia, intravenous atypical vascular proliferation, intravascular fasciitis, and organized thrombus.

Adult↗

PubMed2006

Pyogenic granuloma formation following placement of the Medennium SmartPLUG punctum plug.

PURPOSE: To report a complication, not previously described, of the Medennium SmartPLUG, which is a new punctal plug with a novel design. METHODS: Two case reports are detailed, including clinical and pathologic photographs. RESULTS: Case 1 is a 58-year-old woman with Sjögren syndrome. Nearly 2 years following placement of a SmartPLUG in her right lower canaliculus, the patient presented with an erythematous, papillomatous growth overlying her punctum. Biopsy demonstrated pyogenic granuloma. Case 2 is a 62-year-old woman with dry eye. Exactly 2 years after a SmartPLUG was place in her right lower canaliculus, she also developed a pyogenic granuloma. After irrigation to remove the plug, the growth decreased in size. CONCLUSION: Pyogenic granuloma can develop as a late complication of the Medennium SmartPLUG punctum plug.

Dry Eye Syndromes↗

PubMed2000

Pyogenic granuloma of the penis--don't squeeze them.

We report the case of a pyogenic granuloma on the shaft of the penis presenting with active bleeding secondary to attempted expression. Previously reported cases have documented such lesions on the prepuce and glans.

Adult↗

PubMed1991

Pyogenic granuloma in children. Treatment with the flashlamp-pumped pulsed dye laser.

Pyogenic granuloma, a rapidly developing, benign vascular nodule often arising in children at sites of trauma in the skin or mucous membrane, was treated successfully with flashlamp-pumped pulsed dye laser in three pediatric patients. Excellent cosmetic results were obtained. The authors suggest that the flashlamp-pumped pulsed dye laser be considered as yet another effective modality in the treatment of pyogenic granuloma.

Hemangioma↗

PubMed1996

Clinical diagnosis and management of hormonally responsive oral pregnancy tumor (pyogenic granuloma).

OBJECTIVE: To present a review of our experience and that of the medical literature in the diagnosis and management of oral pregnancy tumor (pyogenic granuloma), the natural History of the disease, its hormonal etiology, histopathologic features and management strategies. STUDY DESIGN: Medical literature review. RESULTS: This common, benign, hyperplastic oral mucosal lesion is much less familiar to gynecologists and obstetricians than to dentists. CONCLUSION: For practitioners engaged in primary care obstetrics and gynecology, routine oral examination and proper identification of pyogenic granuloma are important to avoid misdiagnosis and overtreatment.

Female↗

PubMed1991

Localized vs generalized pyogenic granuloma. A clinicopathologic study.

We herein report the unusual case of a previously healthy young man who had spontaneous development of multiple lobular capillary hemangiomata disseminated over the integument. Based on the observation that the single lesions exhibited (immuno)pathologic and ultrastructural features similar, if not identical, to those of late-stage pyogenic granulomas, we propose to nosologically include our patient's eruption within the disease spectrum of pyogenic granuloma. As opposed to the occurrence of localized forms of pyogenic granuloma, the disseminated eruption seen in our patient and in other patients whose cases are reported in the literature cannot be ascribed to physical trauma. As some of these latter patients suffered from an underlying malignant neoplasm, it is tempting to speculate that both exogenous (eg, trauma) and endogenous (eg, tumor cells) factors can lead to the release of mediators promoting the development of these vascular neoplasms.

Adult↗

PubMedDate not supplied

Intravenous pyogenic granuloma mimicking pleomorphic adenoma in a fine needle aspirate. A case report.

BACKGROUND: Intravenous pyogenic granuloma (IvPG) is a rare, benign lesion occurring usually as a subcutaneous mass in the neck or upper extremity. The cytologic features of IvPG have not been described before. CASE: A patient presented with a subcutaneous nodule on the lower border of the left parotid area. The clinical diagnosis was bronchial cleft cyst or lymphadenitis, and the fine needle aspiration diagnosis was pleomorphic adenoma. The tissue section, however, disclosed IvPG. CONCLUSION: Evaluation of subcutaneous nodules presenting cytologically as spindle cell lesions may be problematic, particularly in the neck and head region. Such lesions occurring in the parotid area may be interpreted as pleomorphic adenoma of the salivary gland.

Adenoma, Pleomorphic↗

PubMed2006

Successful treatment of a therapy-resistant pyogenic granuloma with topical imiquimod 5% cream.

A 58-year-old man was referred to our department for evaluation and treatment of a therapy-resistant pyogenic granuloma on his right third digit. This biopsy-confirmed lesion was unsuccessfully treated with shave excision and base electrocautery on two separate occasions before the patient presented to our clinic. After completing a 14-week course of twice-weekly imiquimod 5% topical application, this patient's pyogenic granuloma completely resolved. A satisfactory cosmetic outcome was also achieved, with virtually no scarring.

Administration, Cutaneous↗

PubMed1997

Lobular capillary haemangioma (pyogenic granuloma) of the nose.

OBJECTIVE: To present a number of cases with lobular capillary haemangioma (pyogenic granuloma) of the nose; and to discuss the clinical and histopathological diagnosis of this disorder. METHODS: A clinicopathological study of patients diagnosed with nasal lobular capillary haemangioma who were treated at King Abdel Aziz University Hospital, Riyadh from 1986 to 1995. RESULTS: The study group consisted of 12 patients (four males and eight females ranging in age from 17 to 65 years; mean 30.1 years). Clinically, most patients presented with epistaxis and a rapidly growing unilateral haemorrhagic mass. Most lesions were located on the septal mucosa. The clinical impression was misleading in some cases. The histological diagnosis was based on the lobular arrangement of capillaries. One case was initially misdiagnosed as angiofibroma. Excisional biopsy was the mainstay of treatment. One instance of recurrence was recorded. CONCLUSION: This uncommon lesion should be considered in the differential diagnosis of a rapidly growing haemorrhagic lesion within the nasal fossa. Clinical and histological diagnostic pitfalls occur frequently.

Adolescent↗

PubMed2005

Nasal septum giant pyogenic granuloma after a long lasting nasal intubation: case report.

The authors present a case of Pyogenic Granuloma (PG) arising from the nasal septum in the posterior nasal cavity of a patient male sex, caucasian, 32 years old, with a previous history of cranioencephalic trauma, several neurosurgeries for different subsequent neurological problems and the use of a nasogastric tube for feeding (nasal intubation) during 30 days. He underwent surgery in St. Vincent de Paul Hospital (Rio de Janeiro) on May 18, 1993, for the tumor removal and straightening of the nasal septum. Under endoscopic guidance the complete excision of the tumor mass was perfectly done thanks to the excellent exposure of the lesion, provided by the enlarged telescopic view, and the wide access afforded by the septum straighttening plus the cartilaginous septum mobilization through the maxilla-premaxilla approach of Cottle, allied to the lateralization and volume reduction of the right inferior nasal concha, simultaneously performed, thus making lateral rhinotomy or "degloving" unnecessary. The patient is until now (2004) completely free of the lesion operated on. This is the first report in the literature of such a lesion associated to nasal intubation as the triggering agent.

Adult↗

PubMed2006

Pyogenic granuloma on the hand subsequent to friction blister in a hand surgeon.

A case of pyogenic granuloma in a 62-year-old hand surgeon secondary to friction blister is reported. He developed a fast growing, hypertrophic inflammatory papule consisting of exceptionally richly vascularized granular tissue. This dusky red lesion was located on the thenar part of the hand. We find no prior report of PG attributed to friction blister.

Friction↗

PubMed1998

Recurrent gigantic pyogenic granuloma disturbing speech and mastication: a case report and literature review.

A case of gigantic pyogenic granuloma with three recurrences in the lower anterior gingiva is presented. Surgical wide excision of the lesion is the treatment of choice. The tumour must be excised down to the periosteum and the irritants around it removed to avoid recurrence. A contributing factor to the gigantic lesion is hormonal changes during pregnancy. Long-term review for 18 months after the third surgery showed no evidence of recurrence at the surgical site.

Adult↗

PubMed1981

Pyogenic granuloma of the larynx and trachea. A causal and pathologic misnomer for granulation tissue.

Pyogenic granuloma has a diagnostic, lobular arrangement of capillaries that clearly distinguishes it, histologically, from granulation tissue. Recently, the accurate term, "lobular capillary hemangioma" (LCH), has been introduced to emphasize this characteristic appearance. A review of 639 vascular lesions of the oral cavity, upper respiratory tract, larynx, and trachea yielded 73 LCHs. All were located in nasal or oral mucous membranes. Conversely, every one of 62 vascular lesions from the trachea or larynx consisted of granulation tissue, without evidence of LCHs. There were clinical as well as pathologic differences. The LCHs arose spontaneously, whereas each patient with laryngeal or tracheal granulation tissue had a specific history of trauma. Pyogenic granuloma (ie, LCH) does not occur in the larynx or trachea.

Adolescent↗