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At least 253 records · Page 14Linked to original sources
PubMed1979

The clinical evaluation of a new clobetasol propionate preparation in the treatment of otitis externa.

A new preparation containing clobetasol propionate, tetracycline and nystatin was compared with Otosporin in the the treatment of otitis externa. Thirty-two patients with bilateral disease and seventeen with unilateral disease completed the trial. Signs and symptoms were assessed by the clinician initially and at varying times after treatment. Both preparations were effective in relieving the symptoms with the majority of patients noticing improvement within seven days. Clobetasol propionate ear drops were significantly better than Otosporin when assessed on the patient's last visit to the hospital (p less than 0.05). There were less relapses in the clobetasol propionate group than in the Otosporin group.

Adolescent↗
PubMed2003

[Chronic recurrent otitis externa. Excessive ear hygienic care can have sequelae].

Numerous factors may be involved in the development of chronic recurrent otitis externa: altered pH of the cerumen, increased susceptibility to contact allergens (e.g. nickel ear-rings) in atopic patients, the use of instruments for cleaning out the auditory canal, the presence of a foreign body, congential narowing of the auditory canal, or systemic diseases (in particular diabetes mellitus). For diagnostic purposes, the use of the otoscope is mandatory, and swabs to determine the presence of bacteria or fungi are to be recommended. Treatment is dictated by the clinical picture presenting, and may comprise the local application of antibiotic cortisone containing or antimycotic preparations and temponade of the auditory canal (acute inflammatory phase) or pH-stabilizing lotions (chronic dry inflammatory phase) with the aim of ameliorating the frequently highly troublesome pruritus.

Cerumen↗
PubMed1997

[Otitis externa among users of private swimming pools].

The purpose of this study was to detect risk factors for developing otitis externa (OE) with special regard to swimming in private pools in holiday houses. Data were collected in a retrospective case-control study from June to October in 1993 and over the same period in 1994. Patients who had OE diagnosed by a general practitioner were included. In 1993 controls were 134 guests from 27 holiday houses where nobody got o.e. during their stay. The number of cases was 35. In 1994 the design was changed so that controls were the 95 healthy inhabitants from the same houses as the 23 cases. The amounts of time spent in the pools and the total bacteria count in the water were significant risk factors for developing OE. Pseudomonas aeruginosa was found in 80% of the ear swabs of the casegroup. In 1993 30% and in 1994 83% of the pools fulfilled the requirements for public pools set by the Danish authorities.

Adult↗
PubMed2003

The Canterbury technique for canalplasty via an endaural approach in the surgical management of chronic refractory otitis externa.

We describe an endaural technique for soft tissue and bony meatoplasty and canalplasty in the surgical management of chronic otitis externa unresponsive to medical treatment and out-patient microsuction. Following analysis of the surgical outcome via a retrospective review of patient records, we would recommend this surgical treatment in this patient group.

Adolescent↗
PubMed1997

New combination for the therapy of canine otitis externa. II. Efficacy in vitro and in vivo.

A new, effective drug combination was developed for the therapy of canine otitis externa (OE) by taking into consideration the microorganisms most frequently isolated from dogs affected with OE, their combination, their drug sensitivity and the type and incidence of ear canal inflammation. The antimycotic active ingredient of the combination is ketoconazole, its antibacterial component is gentamicin sulphate, while its antiphlogistic constituent is mazipredone hydrochloride. Based upon the results of in vitro pharmacodynamic tests, the antifungal activity of the combination is superior to that of ketoconazole used alone at the same concentration. A total of 210 dogs affected with OE were treated with the combination: 94.2 per cent of them became clinically symptomless and microbiologically negative in an average of 8.5 days. No adverse reactions were observed in connection with the use of the drug combination. The therapeutic results can be attributed to the high antifungal efficacy of the combination demonstrated in vitro and to the favourable properties of the solvent mixture.

Animals↗
PubMed2000

Otitis externa associated with Malassezia sympodialis in two cats.

The lipid-dependent species Malassezia sympodialis was isolated from two cats with otitis externa. To our knowledge, this is the first report of the isolation of lipid-dependent species of the genus Malassezia associated with skin disease in domestic animals.

Animals↗
PubMed1991

A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs.

A topical preparation containing miconazole, polymyxin and prednisolone was shown to be more effective in the treatment of otitis externa in 167 dogs than 2 other ear preparations containing antibiotics, an antimycotic and a corticosteroid. With miconazole, polymyxin and prednisolone, the recurrence rate was 26.7% compared with 72.6% and 54.3% when the other products were used. The mean duration of treatment required to achieve resolution of clinical signs was 9.6 days, compared with 12.2 days and 13.0 days and no cases failed to respond to treatment, compared with 17.7% and 14.3%. Malassezia canis alone (71%) or in association with bacteria (18%) was recovered from 44 of 49 ears cultured.

Administration, Topical↗
PubMed1990

[Malignant otitis externa and HIV antibodies. A case report].

The AA. inform about the case of a young man, 23, with immunodeficiency (positive HIV antibodies) and malignant otitis externa associated. They recall the etiopathogenesis, the diagnosis, the evolution and the treatment of the disease, pointing out that this case is the first one (published in the ENT bibliography) of malignant otitis-external otitis and HIV linked together.

Acquired Immunodeficiency Syndrome↗
PubMed1990

Do patients with otitis externa produce biochemically different cerumen?

As polyunsaturated fatty acids have better antibacterial properties than saturated fatty acids, the cerumen of seven patients with recurrent otitis externa and seven unaffected subjects was analysed to determine their ratio. There was no significant difference in either the overall ratio of unsaturated/saturated fatty acids or in the amounts of the individual fatty acids from the cerumen of either group.

Cerumen↗
PubMed1979

The therapy of otitis externa.

The clinical findings following the instillation of an aqueous solution containing natamycin, neomycin and hydrocortisone into the ears of dogs exhibiting the signs of otitis externa are described. Out of a total of 143 cases, 50 were also examined microbiologically both before and after treatment in order to evaluate the antibacterial and antifungal properties of the solution. The severity of the complaint appeared to be of little significance as far as the respons is concerned. A favourable response was noted clinically in 95% and microbiologically in 86% of the cases treated.

Animals↗