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At least 253 records · Page 14Linked to original sources
PubMedDate not supplied

Traumatic ear canal separations and para-aural abscessation in three dogs.

Three dogs were presented for para-aural abscessation. Ear canal separations were suspected preoperatively, based on histories of trauma, physical examination findings of minimally inflamed external ear canals with abrupt endings, and radiographic evidence of discontinuity of the ear canals. Concurrent otitis media, based on radiographic findings, was diagnosed in all three dogs. Disruptions of the external ear canals were confirmed at surgery, and the dogs each responded to total ear canal ablation and lateral bulla osteotomy.

Abscess↗
PubMed1998

Infectious dermatitis in a ball python (Python regius) colony.

Seven wild-caught ball pythons (Python regius), including six gravid females and one male, were obtained from Africa and were housed in a government animal facility in Research Triangle Park, North Carolina. Upon arrival, the snakes were found to be infested with ticks (Aponomma latus), which were manually removed. Four weeks following arrival, vesicular skin lesions began to appear on the snakes. Despite treatment of all affected female snakes with amikacin (5 mg/kg i.m., every 3 days) and cefotaxime (25 mg/kg i.m., every 3 days), the condition progressed and five of the female snakes died 7 wk after arrival. The remaining male and one female improved after an increase in environmental temperature, with ecdysis followed by healing. Physiologic stress, ectoparasites, and shipping may have predisposed the snakes to sepsis.

Amikacin↗
PubMed1985

[Obtaining antisera to Pseudomonas aeruginosa and Proteus antigens for performing immunoenzyme analyses in clinical practice].

The data presented in this work indicate that specific antisera to P. aeruginosa and Proteus antigens can be produced by using extracts from these microorganisms, destroyed by ultrasonic treatment or by multiple freezing and thawing, for the immunization of rabbits. Blood serum samples from patients with purulent septic complications were studied for the presence of P. aeruginosa and Proteus antigens in ELISA with the use of peroxidase-labeled antibodies from antisera to P. aeruginosa and Proteus. This investigation revealed that during the first 3 days from the beginning of the clinical manifestations of the complications P. aeruginosa and Proteus antigens were detected in 86.4% and 83.4% of the patients, respectively. In the subsequent bacteriological study of wound discharge from these patients the corresponding microflora was detected.

Animals↗
PubMed1980

Malignant external otitis in infants.

The authors report two cases of malignant external otitis in infant boys, 5 and 6 months old respectively, caused by different etiologic agents (Pseudomonas aeruginosa and Proteus mirabilis). Both of them were in very poor general health, but neither developed complications such as facial paralysis because of the intensive treatment that was employed from the beginning.

Humans↗
PubMed1976

[Resistance of clinical strains of Proteus to various beta-lactam antibiotics].

Sensitivity of Proteus clinical strains to benzylpenicillin, ampicillin and ceporin, as well as the dynamics and stability of the drug resistance was studied. It was found that the beta-lactamides were active against Proteus, ceporin being the most effective antibiotic. Strains resistant simultaneously to 2 or 3 drugs were also resistant to higher concentrations of each of them. The Proteus cultures isolated from various pathological materials did not differ by their sensitivity to benzylpenicillin and ceporin, while the strains isolated from the patient urine were least sensitive to ampicillin. The cultures of Proteus vulgaris were more resistant to the beta-lactamides as compared tcal material were more resistant to benzylpenicillin and ceporin as compared to the cultures in the H-form. No increase in the number of the Proteus strains resistant to benzylpenicillin, ampicillin or ceporin was observed within 1968-1973. The Proteus resistance to ampicillin and ceporin was not stable and was lost on storage. Reversion to sensitivity depended on the individual properties, the period of storage and the resistance level. The studies showed that the clinical strains of Proteus preserved their sensitivity to the above beta-lactame antibiotics which provided their recommendation for therapy of Proteus infections.

Ampicillin↗
PubMed1975

3-Substituted 2-formylquinoxaline 1,4-dioxides.

The methylnitrone of 3-methyl-1,4-dioxidoquinoxaline-2-carboxaldehyde (1) has been exceptional antibacterial activity in vivo. Derivatives of 3-hydroxymethyl-1,4-dioxidoquinoxaline-2-carboxaldehyde and 3-acetoxymethyl-1,4-dioxidoquinoxaline-2-carboxaldehyde were prepared. Several of these compounds were found to be antibacterial agents of the same order of activity as I.

Animals↗