PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Tuberculin Test”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 253 records · Page 14Linked to original sources
PubMed1995

Evaluation of two-step tuberculin testing in a Massachusetts correctional facility.

OBJECTIVES: To better identify inmates with tuberculosis infection at admission and to have more accurate estimates of conversion rates with annual retesting, I evaluated two-step tuberculin skin testing of newly admitted inmates at the Addiction Center of the Massachusetts Department of Corrections. METHOD: In a population of inmates admitted to the Addiction Center between January and May 1994, a second tuberculin skin test was performed 1 week after the first for those who initially had a negative response. RESULTS: There were 628 admissions during the study period; 51 of these inmates (8%) had a history of positive skin test results. Of the 570 initial tuberculin skin tests that were read, 12 (2.1%) had positive results. Five of 510 second tuberculin skin tests (1%) had positive results. CONCLUSION: I evaluated the feasibility and utility of two-step tuberculin skin testing among newly admitted inmates at a Massachusetts correctional facility. We identified 40% more inmates with positive tuberculin skin test results after conducting 510 additional skin tests. Unlike the Addiction Center inmates, newly admitted inmates at other reception facilities are subject to interfacility transfer, and the rate of reading initial tuberculin skin tests is significantly lower than the 99% obtained at the Addiction Center. I expect serial testing to increase the identification of tuberculosis infected inmates at all facilities; however, its implementation should be deferred until a higher reading rate is obtained for the initial skin test.

Adult↗
PubMed2004

Use of intermittent rifampin and pyrazinamide therapy for latent tuberculosis infection in a targeted tuberculin testing program.

BACKGROUND: To determine the rates of hepatotoxicity and treatment completion associated with intermittent rifampin and pyrazinamide (RZ) therapy for latent tuberculosis infection, we evaluated a cohort of patients from a targeted tuberculin testing site in Tennessee. METHODS: From 4 February 2000 through 9 November 2001, a total of 423 patients with latent tuberculosis infection received directly observed preventive therapy (DOPT) with RZ given twice weekly for 2 months. Most of the patients were young, Hispanic males who had recently immigrated to the United States. RESULTS: During treatment, hepatotoxicity developed in 29 patients (6.9%; hereafter referred to as "case patients"), and peak alanine aminotransferase (ALT) levels that were >10 times the upper limit of normal were noted in 18 case patients. Of the case patients, 14 had asymptomatic hepatotoxicity, and 2 required hospitalization; none of the case patients died. Hepatotoxicity developed after the receipt of 12 doses in more than half of the case patients, and 4 case patients received all 16 doses. The risk of RZ-associated hepatotoxicity was independently associated with older age (odds ratio [OR], 1.07 per year; P=.01). In total, 352 patients (83.2%) completed RZ therapy. The strongest predictors for noncompletion of RZ treatment were the development of a clinical symptom (OR, 9.73; P<.001) and older age (OR, 1.08 per year; P=.001). CONCLUSIONS: Despite the use of DOPT, intermittent dosing, and vigilant monitoring throughout therapy, RZ was associated with an unacceptable risk of hepatotoxicity.

Adolescent↗
PubMed1987

[Present value of tuberculin tests in sarcoidosis].

Under present epidemiological conditions of tuberculosis in our country tuberculin skin tests were done in 103 patients suffering from sarcoidosis. These results were compared with those of patients suffering from other lung diseases. The patients with sarcoidosis show more negative tests (66%) than the others. In inactive cases of sarcoidosis especially in cases with an acute course in the beginning conversion of tuberculin skin test may be seen. This effect may be used for evaluation of the activity of the disease.

Adolescent↗
PubMed2003

Tuberculin testing and risk of tuberculosis infection among New York City schoolchildren.

OBJECTIVES: To assess adherence to a 1996 health policy change, which discontinued mandatory tuberculin skin testing (TST) of new entrants to NYC primary schools and continued mandatory testing of new entrants to secondary schools. METHODS: The proportion tested before (1991-1995) and after (1996-1998) the change in health policy was determined. Factors associated with TST positivity and the cost of continued testing were assessed. RESULTS: A total of 76.6% of 551 636 new entrants to primary schools were tested in 1991-1995; slightly fewer, 71.1% of 339 958, were tested in 1996- 1998. Among new entrants to secondary schools, 31.0% of 106 463 were tested in 1991-1995 and 51.4% of 53 762 were tested in 1996-1998. The proportion who were TST-positive continued to decrease after 1996 to 1.2% among primary and 9.7% among secondary schoolchildren in 1998. Older age and birth outside the United States were associated with TST positivity. The estimated minimum cost of continued testing in primary schools was $123 152 per tuberculosis case prevented. CONCLUSION: An approach aimed at reducing testing of children at low risk for latent tuberculosis infection did not decrease testing of younger children. More important, older children who were more likely to be born in countries of high tuberculosis incidence were not tested. Additional efforts are needed to increase awareness among medical and school personnel to decrease testing among children who do not have risk factors for latent tuberculosis infection and to increase tuberculin testing of children who are entering school for the first time at the secondary level and do have risk factors for tuberculosis infection.

Adolescent↗
PubMed1980

False-positive tuberculin test in Behçet's syndrome.

In a patient with active Behçet's syndrome, every needle puncture produces a pustule. We report herein a patient with Behçet's syndrome that presented as uveitis and erythema nodosum and developed later to the full blown picture of the disease. Reaction to a tuberculin test was found to be strongly positive, since it involved a needle puncture. The test was interpreted as if the patient was tuberculous.

Behcet Syndrome↗