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Abnormalities, Multiple↗

[Prenatal diagnosis of visceral malformations by ultrasonography].

The authors study a series of 64 cases of neo-natal visceral malformations which diagnosis had been done through maternal ultrasonography. The benefits of this technic depend on the affection or the malformation; they are presented here separately. These very early diagnosis in some rare cases allow an antenatal therapy; specially in urology, an earlier surgery than usual can be provided. A case of antenatal diagnosis of Cantrell Syndrome is described.

Abdominal Muscles↗

[Extracardiac malformations in infants with congenital heart diseases: clinical research and statistics covering period 1969-79 (author's transl)].

The authors have examined the statistics of extracardiac malformations in infants with congenital heart disease, aged between birth and 12 months. Cases have been registered and studied within a period ranging from 1969 to 1979 at A. Meyer Hospital of Florence (Pediatric Institute of the University, Divisions of Medical Pediatrics and of Pediatric Surgery). Extracardiac abnormalities occur in 23,05% of infants seen during the first year of life for significant cardiac disease. Sometimes the extracardiac malformations are multiple and 66,3% of the affected infants have some established syndrome, especially chromosomal. The most frequent associated cardiac malformations are: ventricular septal defect (29,3%), complex heart disease (18,5%), non cyanotic heart disease with increased pulmonary blood flow (16,3%) and endocardial cushion defect (10,8%).

Congenital Abnormalities↗

[The level of alpha-feto protein in amniotic liquor. The antenatal diagnosis of some malformations (author's transl)].

We have measured the levels of alpha-feto protein in 127 samples of amniotic fluid, obtained in the course of antenata diagnosis, using the immunoelectrophoretic method of Laurell. The mean, the upper limit of normal and the extreme levels of alpha-feto protein in liquor have been calculated for each gestational age. The difficulties which have been met with in interpreting the results (false positives and false negatives) have been discussed.

Amniotic Fluid↗