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Limitations of radiology in the differentiation of diverticulitis and diverticulosis of the colon.

While barium enema is the most useful investigation in the primary diagnosis of diverticular disease of the colon, this paper presents further evidence that the terms "diverticulosis" and "diverticulitis" are unsatisfactory and shows that a radiological classification on the traditional criteria is not accurate in determining whether or not inflammation is associated with colonic diverticula.

Acute Disease↗

Effect of methylcellulose on rectal and colonic pressures in treatment of diverticular disease.

Six patients with diverticular disorder confirmed by barium-enema examination were given a six-month course of methylcellulose (Celevac) tablets; their rectal and rectosigmoid colonic pressures were measured before and afterwards. Open-tipped, fluid-filled, narrow-bore polyethylene tubes were used for pressure measurements and care was taken to site the tubes similarly in all patients before and after treatment. After methylcellulose treatment the mean rectosigmoid pressures had fallen to the same range as the mean rectal pressures, a highly significant reduction. Methylcellulose significantly reduces rectosigmoid pressures in diverticular disease.

Aged↗

Natural history of diverticular disease of the colon. A review of 521 cases.

In a survey of the natural history of 521 patients with diverticular disease of the colon half of the patients had had symptoms for less than one month on presentation at hospital, and these carried the highest morbidity and mortality. Progression of the disease was usually within segments initially involved, and extension to other regions of the colon rarely occurred. The overall prognosis of patients with total colonic involvement was similar to those with localized disease, while the morbidity and mortality associated with a recurrent attack were higher than in the initial acute episode.

Adult↗

Reappraisal of clinical features of diverticular disease of the colon.

In patients with diverticular disease of the colon factors which indicate a worse prognosis include widespread abdominal pain, nausea and vomiting, disturbed bowel habit, a palpable abdominal mass, abdominal distension, and any of the inflammatory complications. While radiology is of prime importance in the initial diagnosis, it is often impossible to differentiate between diverticulosis and diverticulitis. A more accurate distinction can be made by assessing all the available clinical, radiological, and pathological data, but again there are limitations and inaccuracies. The use of the term "diverticular disease" is preferable.

Abdomen↗

Rectal and colonic studies after resection of the sigmoid for diverticular disease.

Spontaneous basal rectal activity, recorded after resection of the sigmoid colon for diverticular disease, was more than twice the normal. The rectum of post-resection cases yielded a markedly exaggerated overall response to prostigmine, in addition to producing abundant fast wave patterns. The response to stretch of the apparently normal colonic muscle remaining after resection of the sigmoid for diverticular disease resembled unresected diverticular segments, though less in degree, suggesting that a fundamental disorder of colonic muscle may be involved in the aetiology of colonic diverticula.

Colon↗