[8th consensus conference on resuscitation and emergency medicine. Weaning from mechanical ventilation in adults, predominant neurologic and muscular diseases excluded].
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The successful management of 2 cases of rare myopathies, who underwent hemithyroidectomy, is here reported. Anaesthesia was induced with TPS and fentanyl, and maintained with isoflurane. Neuromuscular blockade was achieved by atracurium; neuromuscular monitoring by Neurostar-Medeleck was performed. This intraoperative monitoring allowed a quick recovery without complications.
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An automatic diagnostic tool for neuromuscular diseases, based on the feature extraction and classification of myoelectric patterns using neural network is described. Electromyogram (EMG) signals are extracted from the patients during maximal contraction using needle electrodes. This EMG signal is digitized at a rate of 1000 samples/second. The myoelectric signal is divided into many time segments. Five time domain features are extracted from each of these segments and are averaged over the segments to obtain one feature set. This is applied to the neural network for classification. Results are presented for the diagnosis of polymyositis.
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Inflammatory myopathies are rare diseases with an annual incidence of about 1-8 per 1 million persons. However, they are of special importance in myology as they can be treated successfully. There are auto-immune mediated and infectious forms of myositis. From the clinical and myopathological view, one can distinguish acute and chronic forms: the former presenting with distinct inflammatory reactions in the muscle tissue and often causing myalgia. Muscle atrophy, the latter presenting with marked muscle weakness, often with clear muscle atrophy and mesenchymal abnormalities in the biopsy. Ultrasound well documents muscle atrophy, sometimes compensatory hypertrophy, as well as mesenchymal abnormalities such as lipomatosis and fibrosis. In very acute myositis, as in pyomyositis muscle edema and abscesses can be depicted. Typical findings in autoimmune mediated myositis are reported based on our own experiences in 75 patients and according to the literature. The degree and distribution of muscle atrophy and mesenchymal abnormalities visualized by ultrasound can give clues to the type and prognosis regarding muscle function. Additionally, ultrasound can be used for searching the optimal biopsy site.
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Without doubt respiratory improves life conditions and quality of life of people suffering from neuromuscular disease. Concerning medical-technical possibilities there are only few problems. The respiratory machines, developed during the last years, allow an outpatient treatment with special masks as well as with help of tracheotomy. Yet the medical concept has only small effects if there is something wrong with the psychosocial and psychological conditions. Considering the fact that respiratory prolongs patients life but does not cure, there is a serious problem for patients, their families, the nursing staff and-more and more doctors. For the patients and their families as well as the nursing staff it is necessary to get qualified at time for the outpatient situation already before dismission from hospital. Afterwards they need additional advice and support for solving the daily-life-problems and for saving care-quality in an extensive sense.