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At least 271 records · Page 15Linked to original sources
PubMed1988

Oral squamous cell carcinoma in identical twins: report of a case.

This case report describes two middle-aged identical female twins with a mild to moderate history of tobacco and alcohol abuse who developed squamous cell carcinomas in the same anatomic sites. By exclusion of major factors, a correlation between heredity and the incidence of cancer in these cases appears likely; however, carcinogenic agents (tobacco and alcohol) must also be considered as contributing factors. Close observation of siblings (and certainly twins) is recommended when head and neck carcinoma occurs prior to middle age. Although no genetic population prone to oral cancer is known, the disease is rare enough in younger individuals to raise the question of a possible genetic predisposition.

Adult↗
PubMed1988

Familial occurrence of oral cancer: report of cases.

Four cases of familial occurrence of oral cancer are described and the postulated causes and predisposing factors of oral cancer are reviewed. None of these factors could satisfactorily explain the unusual familial occurrence observed in the cases presented.

Adult↗
PubMed1989

Rhabdomyosarcoma of the parapharyngeal space in an adult patient: an immunohistochemical study.

Rhabdomyogenic malignancies occasionally challenge the diagnostic acumen of many pathologists. The diverse histologic patterns of RMS can range from the somewhat undifferentiated primitive to the bizarre, pleomorphic varieties. These neoplasms can be highly lethal and, until recently, were resistant to even the most aggressive surgical management. The grave prognosis for patients with RMS has remarkably improved however, as a result of careful clinical staging, awareness of histologic features and immunohistochemical techniques for identification, newer techniques in defining the extent of the disease, and multimodal therapy consisting of surgery, radiation, and chemotherapy. Immunohistochemical methods with specific antibodies, as used in this case, have proved to be the only definitive method to identify this variant subclass of RMS.

Adult↗
PubMed1994

The temporalis muscle flap: an evaluation and review of 38 cases.

This article analyzes the authors' experience with the temporal myofascial flap in orbital, maxillary, floor of the mouth, tongue, retromolar trigone, and buccal mucosa reconstruction after oncologic surgery. Thirty-eight patients were treated and evaluated after using this technique. Four of the patients received the flap to restore orbital defects; the other 34 flaps were used in oral reconstruction. The flap remained viable in all instances. Most of the patients experienced no perioperative complications. Ten patients (29.4%) with flaps transposed to the oral cavity showed partial wound dehiscence. Two patients experienced temporomandibular joint dysfunction, two severe reduction in the oral aperture, 22 had mild depression of the temporal fossa, and four had mild to severe alteration in the facial aesthetics secondary to bone resection. All flaps transposed to the oral cavity showed good epithelialization and adaptation to the recipient site.

Adolescent↗
PubMed1980

Intracytoplasmic desmosomes in tumor cells.

The occurrence of intracytoplasmic desmosomes in some normal and tumor cells was suggested to develop by cell fusion by previous investigators. In this study, similar structures were found in tumor biopsies and tumor cells in culture. It is suggested that these structures develop by membrane incorporation and dissolution in cells with active membrane turnover.

Cell Membrane↗
PubMed1983

Intra-oral cone radiation therapy for selected carcinomas of the oral cavity.

A study of 101 patients with early carcinomas of the oral cavity, T1 and T2, treated by external cobalt 60 beam and/or intra-oral cone (IOC) radiation therapy between 1964 through 1980 was made. The two year disease-free survival rate, including surgical salvage, was 88% and the local control rate was 85%. The incidence of radiation complications, i.e. soft tissue ulceration and/or osteoradionecrosis, was 14% and varied with various tumor sites and radiation doses delivered. The present review shows that local control and radiation complications are closely related to radiation doses and varies with different tumor sites of the oral cavity. Radiation therapy dosages expressed in terms of TDF values for these lesions are herein recommended. With proper selections of lesions arising from the oral cavity, combined external beam and IOC radiation therapy has been found extremely efficacious in achieving good local tumor control and high survival rates with excellent cosmetic and functional results and minimum radiation sequelae.

Humans↗
PubMed1988

Interstitial and external radiotherapy in carcinoma of the soft palate and uvula.

Forty-three patients, all male, with limited epidermoid carcinoma of the soft palate and uvula were treated by interstitial implant usually associated with external radiotherapy. Most patients received 50 Gy external irradiation to the oropharynx and neck followed by 20-35 Gy by interstitial iridium-192 wires using either guide gutters or a plastic tube technique. Twelve primary tumors and two recurrences after external irradiation alone had implant only for 65-75 Gy. Total actuarial local control is 92% with no local failures in 34 T1 primary tumors. Only one serious complication was seen. Overall actuarial survival was 60% at 3 years and 37% at 5 years but cause-specific survivals were 81% and 64%. The leading cause of death was other aerodigestive cancer, with an actuarial rate of occurrence of 10% per year after treatment of a soft palate cancer. Interstitital brachytherapy alone or combined with external irradiation is safe, effective management for early carcinoma of the soft palate and uvula but second malignancy is a serious problem.

Actuarial Analysis↗
PubMedDate not supplied

Use of the palatal flap for closure of an oronasal fistula.

Palatal obturators are frequently used in the initial treatment of postoperative palatal fistulae to address the associated problems experienced with speech and swallowing. Many reconstructive surgical techniques for palatal defects have been reported. Although palatal-based flaps are less frequently reported, they can offer a relatively simple reconstructive option with minimal morbidity in patients with acquired palatal defects. We present a case report of a patient requiring reconstruction of a midline oronasal fistula after resection of a palatal malignancy and review the literature concerning this technique.

Female↗
PubMed2004

Synovial sarcoma of the hard palate.

Synovial sarcoma is a rare soft tissue tumour of uncertain histogenesis and intraorally they occur mainly in young adults. We present a case of synovial sarcoma of the hard palate in a 68-year-old woman. To our knowledge, there is no previously reported instance of this tumour at this site.

Aged↗
PubMed2005

Common benign oral soft tissue masses.

This article reviews some of the more common benign oral soft tissue masses with emphasis on their etiology, epidemiology, clinical presentation, histopathology, and treatment. These lesions include traumatic fibroma, mucocele, warts/papilloma, pyogenic granuloma, peripheral giant cell granuloma, generalized gingival hyperplasia, gingival fibromatosis, lateral periodontal cyst, lipoma, and denture-induced hyperplasia.

Adolescent↗