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At least 271 records · Page 15Linked to original sources

Laboratory evaluation of a disposable half-face mask for protection against ozone.

The ability of disposable half-face masks containing activated carbon to protect against inhaled ozone (O2) (nominal experimental exposure concentration, 0.5 ppm) was tested using a specially designed mechanical device simulating the breathing of a moderately exercising human, and then tested further by 18 volunteers exposed to O2 in a controlled-environment chamber for 2 h with intermittent mild exercise. As a control experiment, masks containing no activated carbon were tested similarly. On the mechanical device, carbon-impregnated masks removed 96 to 98% of ambient O3, whereas masks with no carbon removed 32 to 37%. Volunteers experienced typical respiratory irritation and temporary loss of forced expiratory function during O3 exposures when they wore the masks without carbon. These untoward effects were substantially reduced when masks containing carbon were worn. Volunteers tolerated the half-masks reasonably well, although some complained of discomfort. Disposable masks may be of significant benefit in protecting sensitive people from O2 exposures that they cannot readily avoid by other means.

Adult↗

The Ramathibodi nasal filter in a simulated human airway: evaluated with laser smoke particles and a laser diode dust portable monitor.

The Ramathibodi nasal filter was specially designed as a personal respiratory protective device. It was attached to a simulated human airway composed of a nasal and pharyngeal model, airway passage and lung model machine. The system was run in a laser smoke particles environment. The laser smoke particles with suspended particulate matter size of less than 15, 10 and 2.5 microns (PM15, PM10 and PM2.5) were selected. The amount of each particle size in the simulated human airway with and without the Ramathibodi nasal filter was measured continuously by a laser diode portable dust monitor. One hundred sample sizes were analyzed by a descriptive statistical method at the Department of Otolaryngology, Ramathibodi Hospital from January to November 1999. The graphic distribution patterns of each residual particle size in the simulated human airway with and without the Ramathibodi nasal filter were compared. The filtration efficacy of the Ramathibodi nasal filter should be tested further by this experimental model. The device could be applied intermittently in adult nasal vestibules.

Dust↗

Nasal model and lung model machine for intranasal stent with filters efficacy evaluation.

Nasal model and lung model machine simulated human respiratory situation with cyclical air flow rate of 2 1/min. They were used to evaluate filtration efficacy of filters in an intranasal stent for laser smoke particles in the Otolaryngology Department, Ramathibodi Hospital from February to June 1998. The filters were three layers of half face mask outer filters. Each of five sets or 10 intranasal stents with filters or Whatman filters was attached at both inlet ends of the nasal model. A Whatman filter collected the maximum particle amount from 10 shots, 10 W and 0.2 s of single pulse mode carbon dioxide laser evaporative field for 5 min which was the same amount passed through filters of the intranasal stent. A high power optical microscope was used to count particle retention in each filter. The mean filtration efficacy of filters in the intranasal stent was 94.4 per cent when compared with that of the Whatman filter. A personal respiratory protective device could be applied in the human nasal vestibule to prevent polydisperse suspended particulate matter in a highly air-polluted area. The nasal model with lung model machine should be tested under different concentrations of laser smoke particles or at the main roadside.

Equipment Design↗

Efficacy of intranasal stent with filters for different laser smoke particle concentration.

Intranasal, hollow, cylindrical, medical grade, silicone stent with two layers and one layer of half face mask outer filter at each end was tested with different concentrations of laser smoke particles. A single pulse mode of carbon dioxide laser smoke particle created suitable polydisperse atmospheric suspended particulate matter amount. The personal respiratory protective device efficacy was done at the Otolaryngology Department, Ramathibodi Hospital from July to September 1998. The Whatman filter had the same laser smoke particle amount that passed through each filter of the intranasal stent. The cyclical air flow rate of 2 l/min in the nasal model was controlled by a lung model machine and respirometer. The particle deposition in filter materials was counted under a high power optical microscope. The filtration efficacy of an intranasal stent with filters for 5, 10 and 20 shots of laser smoke particle were 90.5, 94.6 and 95.6 per cent respectively with a mean of 93.6 per cent. The device application in a human nasal vestibule depended on acceptable nasal air flow resistant in various highly air-polluted areas.

Air Pollutants, Occupational↗

Evaluation of half-mask respirator protection in styrene-exposed workers.

OBJECTIVE: The protection afforded by respirators to styrene (St)-exposed workers varies considerably. Our objective was to study the effective 'in the field' reduction in St exposure obtained by negative-pressure half-mask respirators worn by a group of fiberglass-reinforced plastics (FRP) workers. Protection was evaluated by measuring the reduction in urinary St (StU) excretion. METHODS: Seven FRP workers not using respiratory protection devices were studied for a week. External exposure to St was evaluated by personal passive sampling, and the internal dose by StU measurement. Then workers were asked to use a half-mask respirator for a week for the entire morning half-shift, and St exposure and internal dose were re-assessed. RESULTS: Mean environmental levels of St during the morning half-shift were 230-280 mg/m3, i.e., about three times the current limit proposed by ACGIH; the difference among days was not significant. Using respirators was accompanied by a large inter-individual and also intra-individual variability: the estimated reduction of StU values ranged from 30% to 90% (mean 60%). Mean StU values increased by 50% from Monday to Friday, while environmental St concentrations remained steady. Furthermore, the proportion of workers exceeding the biological equivalent exposure limit (BEEL) was 14% on Monday, double (33%) on Thursday, and triple (43%) on Friday. These data suggest a decrease of protection during the week. CONCLUSIONS: The protection afforded by negative-pressure half-mask respirators varies widely, which stresses the need to assess the effective reduction of exposure whenever these devices are introduced for St-exposed workers. If respirators are to be re-used for several days, their performance must be evaluated during the last shift of use. Measurement of urinary excretion of unmodified St proved a useful tool for the evaluation of respirator effectiveness in exposed workers.

Air Pollutants, Occupational↗

Organic vapor (OV) respiratory cartridge testing--potential Jonas model applicability.

More efficient methods of characterizing organic vapor (OV) respirator performance against the wide range of compounds and environmental conditions found in industrial settings are needed to improve respiratory protection in the workplace. One method, based on Jonas' kinetic model, has potential application for evaluating OV cartridges and more efficiently utilizing available research, testing and certification resources. Jonas has shown that the kinetic adsorption capacity and gas adsorption rate of a small packed charcoal sorbent bed is described by the linear relationship between gas breakthrough time and sorbent weight as predicted by the modified Wheeler equation. This research is based on the hypothesis that characterizing sorbent performance against a reference compound will allow prediction of breakthrough times, and therefore prediction of cartridge life, for other compounds under similar conditions. Baseline data on dried cartridges at dry conditions are presented that demonstrate that the linear relationship between breakthrough time and and sorbent weight that Jonas showed for small sorbent columns also holds when commercially manufactured respiratory cartridges are stacked in series to resemble a packed column of varying bed length and sorbent weight. This suggests the potential applicability of the Jonas model for characterizing and evaluating commercially available OV respirator cartridges.

Acetone↗

Dose response effect of cement dust on respiratory muscles competence in cement mill workers.

Electromyography (EMG) of respiratory muscles is a reliable method of assessing the ventilatory muscle function, but still its use has not been fully utilized to determine the occupational and environmental hazards on respiratory muscles. Therefore, EMG of intercostal muscles was performed to determine the dose response effect of cement dust on respiratory muscles competence. Matched cross-sectional study of EMG in 50 non-smoking cement mill workers with an age range of 20 - 60 years, who worked without the benefit of cement dust control ventilation or respiratory protective devices. EMG was performed by using surface electrodes and chart recorder. Significant reduction was observed in number of peaks (p < 0.0005), maximum peak amplitude (p < 0.0005), peak-to-peak amplitude (p < 0.0005) and duration of response (p < 0.0005) in cement mill workers compared to their matched control. Cement dust impairs the intercostal muscle competence and stratification of results shows a dose-effect of years of exposure in cement mill.

Adult↗

Steady state respiratory responses to tasks used in Federal testing of self-contained breathing apparatus.

A portion of Title 30, Part II, CFR calls for a Man Test, which is a series of regimens performed with a breathing apparatus. The respiratory responses to the tasks in the Man Test were established on coal miners and students. Based on these responses, the minimal metabolic requirements were derived for the use of breathing apparatuses with a service life of 30 minutes or more.

Coal Mining↗

Effects of pressure-demand respirator wear on physiological and perceptual variables during progressive exercise to maximal levels.

Current regulations governing the certification of respiratory protective devices are based on data published in the early 1950s. The limited data base of this early work and documented increases in the average height of the population underscore the need for additional information concerning the parameters of certification. In the present study, a protocol using an inclined treadmill (0.5% grade every 12 sec) was used to test a heterogeneous population (n = 38). Through submaximal up to and including maximal exercise levels with and without respirator wear, maximal oxygen uptake (VO2max) was significantly greater (p less than 0.01) with the respirator (44.11 +/- 1.3 mL/kg.min) than without the respirator (42.18 +/- 1.4 mL/kg.min) while maximal ventilation volumes (VEmax) were not significantly different (with = 118.7 +/- 4 L/min; without 119.6 +/- 5 L/min). While peak inspired flows (PFI) with the respirator (268 +/- 7 L/min) were less than without the respirator (281 +/- 9 L/min), p greater than 0.05, the lower peak expired flow (PFE) with the respirator (289 +/- 12 L/min) than without the respirator (324 +/- 13 L/min), p less than 0.01, indicated a significant blunting effect of the respiratory flows by the expired resistance during exercise to maximal levels. Peak inspired pressures (PPi) with and without the respirator were not significantly different (p greater than 0.05). The negative values obtained within the facepiece of the respirator (-7.65 +/- 0.8 cmH2O), however, indicate that the positive pressure within the facepiece was lost, and respiratory protection may be compromised. Peak expired pressure with the respirator (13.05 +/- 0.7 cmH2O) was significantly greater than without the respirator (10.7 +/- 0.5 cmH2O) indicating that, despite a lower PFE, greater force was required to overcome the resistances of the respirator on expiration. The dyspnea index, an index of physiological effort; suggests that the subjects were working at a higher percentage of their respiratory reserve with the respirator (p less than 0.05) than without. Perceptually, subjects also felt that breathing with the respirator was more difficult (p less than 0.05). The maximum heart rate and the ratings of perceived exertion were not significantly different between the two tests at maximal exercise levels. Maximum oxygen uptake was considered reached when subjects attained a respiratory exchange ratio of at least 1.15, when a heart rate response at or greater than age-predicted maximum was achieved, when ratings of perceived exertion indicated exhaustion, and/or when the measure of VO2 had plateaued during the final minute of exercise.(ABSTRACT TRUNCATED AT 400 WORDS)

Equipment Design↗

Respiratory protection and the risk of Mycobacterium tuberculosis infection.

Tuberculosis (TB) can be transmitted to susceptible healthcare workers via inhalation of droplet nuclei carrying viable Mycobacterium tuberculosis bacilli. Several types of respiratory protective devices are compared with respect to efficacy against droplet nuclei penetration: surgical masks, disposable dust/mist particulate respirators (PRs), elastomeric halfmask respirators with high-efficiency (HEPA) filters, and powered air-purifying respirators (PAPRs) with elastomeric halfmask facepieces and HEPA filters. It is estimated that these devices permit, respectively, 42%, 5.7%, 2%, and 0.39% penetration of droplet nuclei into the facepiece. More limited data for the disposable HEPA filtering-facepiece respirator suggest that it would allow droplet nuclei penetration of 3% or less, similar to the value estimated for the elastomeric halfmask HEPA filter respirator. Because a respirator wearer's cumulative infection risk depends on the extent of droplet nuclei penetration, the cumulative risk will differ, given use of these different respirators. Hypothetical but realistic "low-exposure" and "high-exposure" scenarios are posed that involve, respectively, a 1.6% and a 6.4% annual risk of infection for healthcare workers. For the low-exposure scenario, the 10-year cumulative risks given no respirators versus surgical masks versus disposable dust/mist PRs versus elastomeric halfmask HEPA filter respirators versus HEPA filter PAPRs are, respectively, 15%, 6.7%, 0.94%, 0.33%, and .064%. For the high-exposure scenario, the 10-year cumulative risks for no respirator use versus use of the same four types of respirators are, respectively, 48%, 24%, 3.7%, 1.3%, and 0.26%. The use of disposable HEPA filtering-facepiece respirator should permit cumulative risks close to those estimated for the elastomeric halfmask HEPA filter respirator. It is concluded that when an infectious TB patient undergoes a procedure that generates respiratory aerosols, and when droplet nuclei source control is inadequate, healthcare workers attending the patient may need to wear highly protective respirators, such as HEPA filter PAPRs.

Aerosols↗

Proposal for an approach with default values for the protection offered by PPE, under European new or existing substance regulations.

Introduction of personal protective equipment (PPE) in the process of quantitative exposure and risk assessment should be addressed carefully. PPE which have been designed and manufactured according to CE-criteria and have proved to pass relevant test criteria, can be classified as "proper functioning". However, test criteria for PPE are not equal to levels of protection which can be achieved in the workplace, because actual workplace exposure scenarios, fit, maintenance and storage may differ substantially from the test conditions. The proper use of PPE is related to issues which form a part of a PPE-programme. Such a programme should be implemented in a company to ensure selection of proper PPE and information, training and instruction of employees how to wear PPE properly. Assigned protection factors (APFs) for different designs of respiratory protective devices (RPD) have been introduced to quantify effectiveness of RPD in the workplace. Similar APFs are proposed for dermal protection (gloves and clothing). In general biological monitoring studies show lower reduction of internal exposure than estimated by reduction of external exposure. Therefore, conservative estimates of protection by PPE, i.e. the lowest APFs, are proposed for risk assessment purposes if "proper use of proper functioning" PPE as part of a PPE-programme cannot be demonstrated.

Accidents, Occupational↗

Efficacy of the helmet respirator in occupational asthma due to laboratory animal allergy (LAA).

The efficacy of the Racal Airstream helmet respirator in preventing symptoms due to Laboratory Animal Allergy (LAA) was assessed in ten patients. Eight of these were established cases of asthma and two had severe rhinitis. Peak expiratory flow rate (PEFR) readings, recorded every two hours, were kept for seven weeks (six in exposure), together with a diary of subjective symptoms. Objective evidence of good protection was obtained in six out of the eight asthmatic patients; overt asthma was seen in the other two. The helmet respirator would appear to be a valuable adjunct in the management of occupational asthma in those who opt to remain in exposure. Those asthmatics who use a helmet respirator need to be monitored carefully and regularly to ensure that their respiratory function has not deteriorated. Persons with severe local symptoms of rhinitis and conjunctivitis also benefit subjectively from the use of the helmet although symptoms are not completely suppressed nor may progression towards asthma be prevented. The findings may well be applicable to the management of other types of occupational asthma but any inferences should be drawn with caution.

Animals↗

The efficiency of respiratory filters in a coke oven atmosphere.

Several types of commercially available respiratory filter/sorbent combinations were tested in a coke oven environment. The percent penetration of benzene soluble particulate and benzo(a)pyrene through these filters was determined and was generally found to be less than ten percent. Degradation of filtering efficiency was noted with some types of filters. The use of a sorbent cartridge in conjunction with a covering filter did not significantly change penetration of the contaminants which were measured.

Analysis of Variance↗

Respiratory cartridge efficiency studies: VIII. summary and conclusions.

The theory of solvent vapor adsorption of activated carbon is reviewed. Calculated and experimental cartridge service life values are compared using various breathing rates, relative humidities, concentrations and solvent vapors. Cartridge service life (the 10% breakthrough time) can be estimated from the emperical expression: t 10% = 2.4 X 10(6) WC (A + BT)/C 2/3 MQ Carbon weight (wc), relative solvent volatility (a, b and t) concentration (C), molecular weight (M) and breathing rate (Q) all play a vital role in cartridge performance predictions.

Adsorption↗

Effect of work load and respirator wear on postural stability, heart rate, and perceived exertion.

The effects on postural stability (sway) were investigated for different work loads under conditions of wearing a full facepiece respirator and not wearing any respiratory protection device. Fifteen subjects accomplished light (40 W), moderate (85 W), and heavy (125 W) work loads under the two conditions. Measurements of postural sway were made immediately after each load by using a multicomponent, strain gage-type force platform. Changes in each subject's movement pattern of the center of pressure were quantitated and compared to their initial baseline sway tests. Each subject's heart rate and perceived exertion were also recorded during each condition. A statistically significant effect (p = 0.007) caused by work load was observed for total length of sway with or without a respirator. An interaction approaching statistical significance (p = 0.056) between work load and respirator use was found. This indicated that sway increased more quickly and in a more consistently linear fashion with increasing work load under the respirator condition (p = 0.02) compared to the nonrespirator condition. The results from the respirator condition showed linear increases in postural sway length across the entire range of work loads, but sway length in the nonrespirator condition showed an increase only at 125-W work loads. The greater increase in sway during the postural balance test could be attributable to the increasing work load-induced proprioceptive fatigue effect on the nervous system's ability to process signals from proprioception systems incongruent with body sway. The heart rate was significantly higher during respirator wear (an increase in heart rate averaging 5.62 beats/min).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗