[The manometric walking test in diseases of veins of the lower extremities].
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Blood Pressure↗
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Results for “Walk Test”
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Arteriography, plethysmography and walking test in arterial obliteration of the legs.
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Adult↗
A portable minute heart rate recorder/decoder system for self-paced walking tests [proceedings].
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Heart Function Tests↗
Effects of balance training in elderly people with nonperipheral vertigo and unsteadiness.
OBJECTIVE: To evaluate the effect of balance training in group in elderly people with nonperipheral vertigo and unsteadiness. DESIGN: Randomized controlled study. SETTING: Ear-, nose- and throat department, University Hospital, Sweden. SUBJECTS: Twenty-three elderly subjects with nonperipheral vertigo and/or unsteadiness randomized into training group and control group. INTERVENTION: The training group attended balance training in group twice a week for eight weeks. MAIN OUTCOME MEASURES: Timed static balance tests, walking tests and six sensory organization tests on EquiTest dynamic posturography were performed before and after the training period. Besides, the patients estimated their vertigo and unsteadiness on a visual analogue scale (VAS) before and after the training period. RESULTS: The training group improved significantly in standing on one leg with eyes open, walking forward on a line, walking speed, in three out of six tests on dynamic posturography and estimated less vertigo and unsteadiness measured with VAS. No changes were seen in the control group. CONCLUSION: Balance training in elderly people with nonperipheral vertigo and unsteadiness seems to improve both objective and perceived balance.
Aged↗
[Quality of life and functional status in congestive heart failure].
OBJECTIVE: To assess health related quality of life of patients with congestive heart failure (CHF), to correlate quality of life with other functional parameters; maximal oxygen uptake (peak VO2) with submaximal tests (two minute walking test and shuttle walk test) and New York Heart Association (NYHA) with other clinical variables. METHODS: We evaluated 35 stable congestive heart failure patients (NYHA II-III). Functional status was assessed by NYHA classification, maximal oxygen uptake (peak VO2) and submaximal tests (two minute walk test and shuttle walk test). Health related quality of life was measured with short form 36 health survey (SF 36). RESULTS: NYHA functional class was correlated with social functioning of SF 36, peak VO2 and shuttle walk test. Peak VO2 was correlated with most of the parameters of SF 36. On the other hand 2 minute walk test and shuttle walk test were correlated with social functioning of SF 36. There was a correlation between peak VO2 and submaximal test, but there was no correlation between left ventricular ejection fraction, peak VO2 and NYHA class. CONCLUSION: Social functioning is impaired in patients with congestive heart failure. There is a correlation between maximal and submaximal tests. The maximal and submaximal tests can explain some degree of quality of life. Functional status can be explained with peak VO2 and shuttle walk test apart from NYHA class.
Adult↗
Effect of the oral endothelin antagonist bosentan on the clinical, exercise, and haemodynamic status of patients with pulmonary arterial hypertension related to congenital heart disease.
OBJECTIVE: To evaluate the clinical, exercise, and haemodynamic effects of chronic oral administration of the non-selective endothelin receptor antagonist bosentan on patients with pulmonary arterial hypertension (PAH) related to congenital heart disease (CHD). DESIGN: Prospective non-randomised open clinical study. SETTING: Cardiology tertiary referral centre. PATIENTS: 21 patients with a mean (SEM) age of 22 (3) years with chronic PAH related to CHD (15 with Eisenmenger's syndrome). Patients were in World Health Organization (WHO) class II to IV with oxygen saturation 87 (2)%. INTERVENTION: Patients underwent clinical, exercise, and haemodynamic evaluations at baseline and after 16 weeks of treatment. RESULTS: Bosentan improved (p < 0.01) WHO class, peak oxygen consumption from 16.8 (1.4) to 18.3 (1.4) ml/kg/min, exercise duration from 9.0 (0.8) to 10.7 (0.6) minutes during the treadmill test, walking distance from 416 (23) to 459 (22) m, and Borg dyspnoea index from 2.8 (0.2) to 2.0 (0.1) during the six minute walk test. Bosentan treatment improved (p < 0.05) mean pulmonary artery pressure from 87 (4) to 81 (4) mm Hg, pulmonary blood flow index from 3.2 (0.4) to 3.7 (0.5) l/min/m2, pulmonary to systemic blood flow ratio from 1.2 (0.2) to 1.4 (0.2), and pulmonary vascular resistance index from 2232 (283) to 1768 (248) dyn.s.cm(-5). Two patients died, presumably of arrhythmic causes, who were in WHO class IV at baseline and who had improved during treatment. CONCLUSIONS: Bosentan induces short and mid term clinical, exercise, and haemodynamic improvements in patients with PAH related to CHD. Larger studies with long term endothelin receptor antagonism are needed to assess the safety and possible treatment role of bosentan in this population.
Administration, Oral↗
The shuttle walk exercise test in idiopathic pulmonary fibrosis.
The shuttle walk test (SWT) is a validated, incremental walking test for chronic obstructive pulmonary disease, but not for idiopathic pulmonary fibrosis (IPF). The measurement of maximal oxygen consumption (VO2 max) is considered to be the gold standard measurement of functional capacity. This study examines the relationship between IPF patients' performance on the SWT and VO2 max. Twenty patients were recruited for the study, which consisted of two separate experiments. Firstly, the relationship between SWT performance on a conventional corridor SWT, with that on a programmable treadmill SWT designed to reproduce the corridor SWT was examined (n=10). In the second experiment, the relationship between performance on the treadmill equivalent SWT and VO2 max measurements was studied (n=10). There was a significant correlation between distance walked on the corridor SWT, and that walked on the treadmill equivalent SWT without VO2 max measurements (367 m vs. 410 m) (r=0.91, P=0.0003). There was a significant correlation between distance walked on the treadmill equivalent SWT (277 m), and the directly determined VO2 max (14.87 ml/kg/min) (r=0.74, P=0.01). During both experiments, a significant correlation was also observed between baseline PaO2 and SWT performance, and between DLCO and SWT performance. The shuttle walk test is a simple objective measure of functional capacity in IPF patients, which should facilitate the evaluation of new therapeutic compounds for IPF.
Exercise Test↗
Simple function tests, but not the modified HAQ, correlate with radiological joint damage in rheumatoid arthritis.
OBJECTIVE: To test the validity of the Modified Stanford Health Assessment Questionnaire (MHAQ) for assessment of physical disability in rheumatoid arthritis (RA). METHODS: Sixty-one RA patients with mean age of 61 years and median disease duration of four years were included in this cross sectional study. The patients completed the MHAQ. Four simple function tests were performed (walk test, chair test, upper extremity mobility test, and grip strength) and a modified Larsen score was established. Pain score (VAS) and laboratory variables for inflammation were recorded. RESULTS: MHAQ, function tests, pain, and C reactive protein (CRP) showed highly significant mutual correlations (p < 0.01). However, MHAQ did not correlate with Larsen score (R = 0.06; NS), while most function tests did (walk test, R = 0.29; p < 0.05; chair test, R = 0.21; NS; mobility test, R = 0.36; p < 0.01 and grip strength, R = -0.35 p < 0.01). The superiority of function tests was even more pronounced after four years (walk test, R = 0.31; p < 0.05; chair test, R = 0.50; p < 0.01; mobility test, R = 0.49; p < 0.01; grip strength, R = -0.52; p < 0.01; MHAQ, R = 0.34; NS). CONCLUSION: Objective function tests are preferable to MHAQ in the assessment of physical disability in RA.
Adult↗
Adding challenge to performance-based tests of walking: The Walking InCHIANTI Toolkit (WIT).
OBJECTIVE: In this report, we provide a detailed description of and reproducibility data on the 14 performance-based tests of lower limb function included in the Walking InCHIANTI Toolkit, which were designed to mimic challenging situations that are encountered while walking in daily life. DESIGN: Five women and five men were randomly selected from each of the age strata, 65-74, 75-84, and > or =85 yrs, among those who received a functional evaluation in the Greve site at the second InCHIANTI study follow-up (total n = 30). Walking tests were administered twice at 2-wk intervals. Analyses were aimed at assessing reproducibility of the Walking InCHIANTI Toolkit components and the existence of a learning effect. RESULTS: Performance remained stable for eight walking tests and slightly but significantly improved for the 25-cm narrow-path walk, 7-m usual-pace, 7-m obstacle normal light, 7-m holding a package, and 7-m talking while walking tests. Test-retest reliability was in general very high, with 11 of 14 (79%) of the intraclass correlation coefficient values >0.80 and all except one (7-m holding a package) >0.75. CONCLUSION: The walking tests included in the Walking InCHIANTI Toolkit show very good medium-term reproducibility and modest learning effect. Administering components of the Walking InCHIANTI Toolkit may help in the understanding of the effect of challenges encountered in daily life on walking performance.
Aged↗
[Objective evaluation of arterial intermittent claudication by the walking tolerance test. Comparative study of physiological walking and walking on a conveyor belt (author's transl)].
Two methods are used to evaluate the walking distance: physiological walking along a standard path (0% - 6 mk/h) and walking on a tread mill (10% - 3 km/h). In both tests, four data are checked: -- initial trouble distance, -- cramp or walking-distance, -- localisation of pain, -- recovery time. These tests are dependable for the diagnosis of arterial claudication, reproducible and well tolerated. Their results have been compared: there is no correlation between the initial trouble distance and the cramp distance. However there is a correlation between the cramp distance by physiological walking and on treadmill. Recovery time, if long, is a criteria of gravity. Interests of both methods are discussed.
Adult↗
Exercise for the dialyzed: aerobic and strength training during hemodialysis.
OBJECTIVE: To investigate the safety and feasibility of aerobic and strength training during hemodialysis for end-stage renal disease patients and to evaluate its impact on their cardiac fitness, muscle strength, and functional status. DESIGN: A total of 22 patients undergoing hemodialysis for end-stage renal disease had assessment of their cardiac fitness with stress tests and walk tests, assessment of their muscle strength by one repetition maximum of knee extension, and assessment of their functional status by Medical Outcomes Study Short Form-36 before and after exercise training. Training, consisting of cycle ergometer exercise and strengthening of the knee extensors two to three times a week for 3 mo, was done during dialysis. RESULTS: Eighteen of 22 patients completed 3 mo of training and four dropped out due to knee pain or medical complications unrelated to exercise. No patient developed major complications from the program. After training, there was a significant improvement in the mental and physical components of the Short Form-36 and one repetition maximum of knee extension. Among 14 of 18 patients who agreed and completed a follow-up fitness testing, five showed improvement on the stress tests and eight on the walk tests. CONCLUSIONS: A well designed exercise program during hemodialysis can be performed safely with proper supervision and patient education, improving muscle strength, mental and physical function, and possibly cardiac fitness.
Adult↗
Back pain, physical function, and estimates of aerobic capacity: what are the relationships among methods and measures?
OBJECTIVES: To establish the correlations of measures of self-reported disability, self-efficacy, physical performance, level of pain, and estimates of aerobic capacity (PvO2 ) in subjects with low back pain. DESIGN: Fifty-one low back pain subjects, ranging in age from 26 to 65 yr, entered the study. Participants completed the Roland-Morris Disability Questionnaire and the self-efficacy questionnaire. Physical performance was evaluated by the loaded-reach test, sit/stand test, 5-min walk test, 50-foot walking test, and time to roll from right to left. Pain intensity and pain affect were measured using two visual analog scales. PvO2 was predicted from an equation. RESULTS: The correlation coefficient among the physical performance outcomes ranged from 0.47 to 0.78. Pain measures had low correlations with measures of function but stronger correlations with other self-report measures. The disability measure correlated moderately with physical performance. Correlations between PvO2 and all other measurements were minimal, except for the 5-min walk test. CONCLUSION: Performance and disability were more consistent in evaluating low back pain. PvO2 failed to correlate with most other aspects of low back pain. This study suggests that aerobic capacity might not be a primary concern for patients with low back pain.
Adult↗
Stride frequency and ventilation at constant carbon dioxide output.
To determine the consequences of two different stride frequencies on ventilation (VE) at similar levels of carbon dioxide production (VCO2), eleven male subjects performed two work tests on the treadmill. One test involved walking at a speed of 5 km/hr on a 15% grade while the other consisted of running on the treadmill at 9 km/hr on a 0% grade. Running increased stride frequency by 47%. The running and walking tests resulted in similar VCO2 levels, 1.85 +/- .18 and 1.9 +/- .20 l/min respectively, a non-significant difference. Ventilation during running was 43.73 +/- 6.51 l/min and during walking was 43.26 +/- 6.79 l/min, a non-significant difference. In addition the time constants for oxygen consumption (VCO2), VE and VCO2 were measured. The time constants for VCO2 and VE were not found to differ significantly during either the running or walking test. From our results, it can be seen that VE is more closely aligned to the metabolic state rather than stride frequency. In addition, the coupling of VE and VCO2 during the non-steady state is further indicative that ventilation is linked to the metabolic demands of the body.
Adult↗
Perioperative exercise programs improve early return of ambulatory function after total hip arthroplasty: a randomized, controlled trial.
OBJECTIVE: Patients with endstage hip arthritis have poor ambulatory function. The aim of this study was to determine if perioperative exercise programs are well tolerated by these elderly patients and if a customized program can achieve an earlier recovery of normal ambulatory function after total hip arthroplasty. DESIGN: Twenty-eight subjects scheduled for total hip arthroplasty were randomized to either the exercise group and received a perioperative customized exercise program or the control group and received the routine perioperative care. Ambulatory function was assessed by measurement of gait parameters during a 25-m walk test, and walking endurance was assessed by a 6-min walk test. RESULTS: Exercise group subjects attended 97.3% of scheduled exercise sessions with no training injuries. Exercise group subjects demonstrated greater stride length and gait velocity at 3 wk postsurgery. At 12 and 24 wk postsurgery, gait velocity was greater, and the 6-min walking distance was significantly greater than the control group. CONCLUSION: The study indicates that perioperative customized exercise program are well tolerated in the elderly patient with endstage hip arthritis and are effective in improving the rate of recovery in ambulatory function in the first 6 mo after total hip arthroplasty.
Aged↗
Comparing pain severity and functional status of older adults without spinal symptoms, with lumbar spinal stenosis, and with axial low back pain.
BACKGROUND: Functional status has been quantified in the adult low back pain (LBP) population, but has not been characterized for older adults with spinal symptoms. OBJECTIVES: To compare pain severity and functional status of older adults with and without spinal symptoms, and to determine what factors are associated with quality of life in the spinal stenosis and axial LBP groups. METHODS: In 24 subjects greater than 55-years old with lumbar spinal stenosis, 12 with LBP, and 12 without spinal symptoms, obtain the following: pain severity with 10-cm visual analog scale (VAS), 15-minute walk test, 7-day walking distance, Quebec Back Pain Disability Scale (QBPDS), and Pain Disability Index (PDI). RESULTS: The mean scores were worst for the stenosis group, were intermediate for the LBP group, and were the best for the asymptomatic group. Analysis of variance showed that the pain VAS (p < 0.001), 15-minute walk test (p = 0.01), 7-day walk (p = 0.02), QBPDS (p < 0.001), and PDI (p < 0.001) were different between at least two groups. All the variables in the stenosis group were worse than in the asymptomatic group, but only the pain VAS, QBPDS, and PDI in the LBP group were worse than in the asymptomatic group. In both the stenosis and LBP group the QBPDS and PDI were only related to pain VAS. CONCLUSION: Seniors with spinal stenosis and LBP have more disability than asymptomatic seniors. The 15-minute walking test with the stenosis group was slower than with the asymptomatic seniors. However, they compensate so that their 7-day walking distance is not as significantly decreased.
Activities of Daily Living↗
Obstacle training programme for individuals post stroke: feasibility study.
OBJECTIVE: The purposes were threefold: to develop an obstacle ambulation training programme, to recruit and retain individuals post chronic stroke and to assess the effectiveness of the obstacle ambulation training programme. DESIGN: Intervention study; case series; baseline to post-intervention measures and one month follow-up after intervention. SETTING: An outpatient department. SUBJECTS: Five individuals with chronic stroke with mild to moderate functional limitations; convenience sample. INTERVENTIONS: Therapy consisted of twice weekly sessions for four weeks during which subjects walked along a walkway and over obstacles. MAIN OUTCOME MEASURES: Motor Assessment Scale--walking section (MAS--time), Six-minute Walk Test distance, walking velocity, and Medical Outcomes Study-36 Health Status Measurement (SF-36). RESULTS: Significant improvements were seen baseline to post intervention for walking velocity, Six-minute Walk Test, MAS and SF-36 physical function score (p < or = 0.025 for all measures). Most improvements noted at the end of training were retained one month later. The effect sizes ranged from 0.33 to 1.20. CONCLUSIONS: Substantial improvement in ambulation function and disability level were seen as a result of the obstacle training programme for individuals with chronic stroke. Further investigation is warranted.
Adult↗
Rheumatology function tests: grip strength, walking time, button test and questionnaires document and predict longterm morbidity and mortality in rheumatoid arthritis.
Four quantitative measures of functional status, grip strength, walking time, the button test, and a questionnaire regarding activities of daily living, were assessed nine years apart in 75 patients with rheumatoid arthritis (RA). After 9 years, 20 patients had died; none were lost to followup. Functional status had declined in more than 80% of patients according to each of the 4 measures, and patients with poor values at baseline were most likely to die over the next 5 years, as reported. We report that baseline values of these measures of functional status were predictive of values 9 years later. These measures may be regarded as "rheumatology function tests" to document and predict morbidity and mortality in RA over long periods.
Arthritis, Rheumatoid↗
[Liposome-mediated glial growth factor 2 gene therapy in brain injury: an experimental study with rats].
OBJECTIVE: To explore the protective effect of glial growth factor-2 (GGF2) on brain injury. METHODS: Thirty-four SD rats underwent lateral fluid percussion to establish brain injury models and then were randomly divided into 4 groups: treatment group (n = 10, the plasmid pEGFP-N1-GGF2 mixed with liposome was injected into the brain tissue directly), vector control group (n = 10, the vector pEGFP-N1 mixed with liposome was injected into the brain tissue directly), liposome control group (n = 10, liposome was injected), and sham operation group (n = 4). Three assessment tasks were performed for neurobehavioral evaluation: Clivas Test, Beam Balance Test and Beam Walking Test. 10 days after brain injury, the rats were sacrificed and their brains were embedded in paraffin for HE staining, Nissle staining and immunohistochemical examination of MBP, NSE, and GFAP. RESULTS: The Clivas test score of the treatment group was 66.25 +/- 3.54, significantly higher than those of the vector control group and. liposome control group (58.31 +/- 3.72 and 57.21 +/- 3.93 respectively, both P < 0.05). The beam test score of the treatment group was 2.59 +/- 0.21, significantly lower than those the vector control group and liposome control group (3.41 +/- 0.25 and 3.24 +/- 0.22 respectively, both P < 0.05). The walking test score of the treatment group was 20.15 +/- 2.59, significantly lower than those of control group and liposome control group (27.00 +/- 3.47 and 27.80 +/- 3.00 respectively, both P < 0.05). The improvement in beam walking test was the greatest. The neuron number in the external granular layer and external pyramidal layer in cortex of the treatment group was 98 +/- 10, significantly more than those of the vector control group and liposome group (75 +/- 7 and 67 +/- 8, both P < 0.05). The neuron number in the internal pyramidal layer in cortex of the treatment group was 37 +/- 4, significantly more than those of the vector control group and liposome group (19 +/- 3 and 23 +/- 4 respectively, both P < 0.05). The neuron number in the CA1 region in hippocampus of the treatment group was 102 +/- 11, significantly more than those of the vector control group and liposome group (67 +/- 8 and 58 +/- 9 respectively, both P < 0.01). Higher level of immunoreactivity with MBP was also detected in the cortex in the rats of the treatment group. CONCLUSION: Cationic liposome-mediated GGF2 gene therapy effectively promotes the recovery of brain injury.
Animals↗