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Cochlear implants in young children.

The cochlear implant is best characterized as a device that provides access to the sound environment. The device enables the hearing pathway to respond to environmental and speech sounds, providing informational cues from the surroundings and from others that may escape visual detection. As the developmental effects of a profound hearing loss are multiple, cochlear implants have been applied to ever younger children in an attempt to promote a more normal level of developmental learning through audition. In deafness, transducer elements of the inner ear fail to trigger auditory nerve afferent nerves in the presence of sound input. However, large reserves of afferent fibers exist even in the auditory nerve of a profoundly deaf patient. Furthermore, these nerve fibers retain the ability to respond to prosthetic activation. Through developmental learning in the early, formative years, auditory centers of the brain appear capable of processing information from the implant to provide speech comprehension and oral language development. Multichannel implants have replaced original single channel designs. multichannel devices enable larger percentages of recipients to recognize the spoken word without visual cues because they provide spectral information in addition to temporal and intensity cues. Testing under conditions of auditory (implant)-only input reveals significant open-set speech understanding capabilities in more than 75% of children after three years of device use. The benefit provided by implants may vary with a number of conditions including: hearing history, age of deafness onset, age at implantation, etiology of deafness, linguistic abilities, and the presence of a motivated system of support of oral language development. Patient variables should be given individual consideration in judging candidacy for a cochlear implant and in planning rehabilitative and education services after surgery and activation of the device.

Child↗

What do cochlear implants teach us about the encoding of frequency in the auditory system?

This article explores the coding of frequency information in the auditory system from the viewpoint of what has been learnt from cochlear implants. Cochlear implants may provide a window on central auditory nervous system function by creating the possibility to separate place and temporal information. An existing model of frequency discrimination in the acoustically stimulated auditory system is extended to include electrical stimulation. To be able to predict frequency difference limens for acoustic stimulation, an important assumption is that one spike per stimulus cycle is available, which may be provided by the existence of a volley principle. It is shown that to predict frequency difference limens for electrical stimulation of the auditory system, it must also be assumed that electrical stimulation causes desynchronization at a central auditory nervous system integration centre. With these assumptions, the model predicts the degradation in frequency discrimination that occurs for electrical stimulation. Finally, it is shown that cochlear implants have not yet proven conclusively that either rate-place coding or temporal coding is predominant in the auditory system.

Auditory Pathways↗

Implant outcomes: towards a mixed methodology for evaluating the efficacy of adult cochlear implant programmes.

Studies concerned with the efficacy of cochlear implants have traditionally focused on measuring enhancements in speech perception associated with implantation. This paper reports the findings of a study concerned with qualitative and quantitative measures of psychosocial benefit associated with the adult cochlear implant programme. Cochlear implants enhanced implantees' interpersonal communication skills and social confidence, and were associated with a reduction in the user's social anxiety. Broader socioeconomic gains were not achieved by implantees, mainly because of an absence of adequate employment and community education programmes associated with implant programmes.

Adult↗

[Professional occupation after cochlear implantation].

This study verifies whether cochlear implants helps deaf adults to maintain or develop their professional occupations. Sixty-seven patients received a questionnaire concerning their professional activities before and after implantation. At the time of implantation 34 were professionally active. After the implantation 29 remained active, 4 of them reporting positive developments in their careers. Five patients became inactive. The previously inactive patients remained inactive. There was no difference in auditory performances between professionally active or inactive patients. Cochlear implants enable most implanted adults to maintain and even progress in their professions. However, deafness still represents an obstacle to social integration as inactive patients who searched for a job were rejected after the job interviews.

Adolescent↗

Trends in cochlear implants.

More than 60,000 people worldwide use cochlear implants as a means to restore functional hearing. Although individual performance variability is still high, an average implant user can talk on the phone in a quiet environment. Cochlear-implant research has also matured as a field, as evidenced by the exponential growth in both the patient population and scientific publication. The present report examines current issues related to audiologic, clinical, engineering, anatomic, and physiologic aspects of cochlear implants, focusing on their psychophysical, speech, music, and cognitive performance. This report also forecasts clinical and research trends related to presurgical evaluation, fitting protocols, signal processing, and postsurgical rehabilitation in cochlear implants. Finally, a future landscape in amplification is presented that requires a unique, yet complementary, contribution from hearing aids, middle ear implants, and cochlear implants to achieve a total solution to the entire spectrum of hearing loss treatment and management.

Acoustic Stimulation↗

Binaural cochlear implants.

With the success of monaural cochlear implantation, patients frequently ask about having a second implant. We have performed binaural cochlear implants in 12 adult patients. Desire not to disrupt a functioning implant was the primary consideration in implanting the contralateral ear. Seven patients received a second 3M/House single-channel implant to upgrade to a magnetic external receiver. Four patients with a 3M/House device in one ear elected to place a Nucleus multichannel implant in the opposite ear. One patient with a poorly functioning Nucleus device elected to have a second Nucleus device. Four patients with a Nucleus and a 3M/House implant, one with binaural 3M/House implants, and one with binaural Nucleus implants were tested for auditory discrimination in order to quantify monaural versus binaural differences. The functional benefit of the second implant was mixed, but all patients showed some degree of objective improvement on one or more tests. Five of the six are regular users of both devices; the patient with binaural Nucleus implants wears only one. Despite the differing processing schemes, patients with a Nucleus device in one ear and a 3M/House device in the other ear are able to combine the two signals to advantage. We feel that cochlear implantation in the contralateral ear is an acceptable option in selected patients desiring an upgraded implant without placing a functioning implant at risk.

Aged↗

A prospective study of the cost-utility of the multichannel cochlear implant.

CONTEXT: Prior clinical studies have indicated that cochlear implantation provides benefits to individuals with advanced sensorineural hearing loss who are unable to gain effective speech recognition with hearing aids. OBJECTIVE: To determine the cost per quality-adjusted life-year (QALY) for adults receiving multichannel cochlear implants. DESIGN: Prospective 12-month multicenter study using preference-based quality-of-life measures and total cost determinations, comparing profoundly hearing-impaired adult subjects with and without cochlear implants. SETTING: Hospital-based and patient-resource clinics. PATIENTS: Severely to profoundly hearing-impaired adult recipients of a cochlear implant and adults eligible for the device who had not yet received it. MAIN OUTCOME MEASURE: Clinical assessment of implant participants included medical and audiologic (speech understanding) data at the time of enrollment, 6 months, and 12 months. All participants' health-utility was assessed at the time of enrollment, 6 months, and 12 months using the Health Utility Index. One-year medical resource utilization and cost data included bills related to implants, patient diaries, charge estimates from clinical sites, and published literature. A decision model was developed to determine cost per QALY. RESULTS: Of the 84 enrolled adults, 62 (75%) completed the study. Mean health-utility scores at the time of enrollment were identical between groups. The marginal 12-month health-utility gain for implant recipients was 0.20; 90% of this improvement was achieved within 6 months. For patients with a mean 22-year life expectancy, the marginal cost per QALY was $14,670. CONCLUSIONS: Overall, multichannel cochlear implants significantly improved recipients' performance on measures of speech understanding and ratings of health-utility within 6 months of implantation. The multichannel cochlear implant yielded a very favorable cost per QALY.

Adult↗

Paediatric cochlear implantation: how reliable is computed tomography in assessing cochlear patency?

This study investigates the accuracy of pre-operative high resolution computed tomographic (CT) scans in predicting the patency of the cochlea in children undergoing cochlear implantation. The first 26 children on the Nottingham Paediatric Cochlear Implant Programme were reviewed. CT scans were performed utilizing 1 mm contiguous sections and these were then assessed by a neuroradiologist. In patients who had normal inner ears on CT a high degree of accuracy in predicting a patent cochlear was achieved (87%). However, in 15% of cases the degree of ossification was significantly under-estimated causing major difficulties at the time of surgery. Although high resolution CT offers great clarity and fine detail, it has its limitations. Further information may be provided by magnetic resonance imaging.

Calcinosis↗

Speech reception thresholds obtained in a symmetrical four-loudspeaker arrangement from bilateral users of MED-EL cochlear implants.

OBJECTIVE: The purpose of the study was to investigate speech reception in noise in subjects who had undergone bilateral implantation with multichannel cochlear implants. METHODS: Nine adults with bilateral MED-EL implants were included in the study. The subjects were tested using both implants and the better implant only. Tests were performed in a symmetrical setup, which ideally eliminates any head shadow effect. Speech tests included sentences in quiet and at various signal-to-noise ratios. From the results, the gain in signal-to-noise ratios at the speech reception threshold was determined. RESULTS: All subjects showed a substantial gain in signal-to-noise ratios of approximately 4 dB on average. In addition, the gain in signal-to-noise ratios was essentially stable for as long as 4.4 years. CONCLUSIONS: The results indicate that bilateral cochlear implant users are able to binaurally process speech.

Acoustic Stimulation↗

Postoperative infection in cochlear implant patients.

OBJECTIVE: Recently, the association of meningitis with cochlear implants has raised concern over the safety of these devices. We examined the incidence of all postoperative infections in patients undergoing cochlear implant surgery. Study design and settings A retrospective chart review of all patients undergoing cochlear implants at a private tertiary referral center from 1993 to 2002 was performed. Cochlear implant surgeries in 462 adults and 271 children were reviewed. Patients with evidence of a postoperative infection or infectious complication related to cochlear implantation were identified, and data on patient characteristics, surgery, and treatment outcome were obtained. RESULTS: The overall incidence of postoperative infection in our cochlear implant series was 4.1%. Major infectious complications occurred in 3.0% of cases, and the majority of infections required surgical intervention. A history of chronic ear disease may increase the risk of infectious complications. There were no cases of meningitis. CONCLUSIONS: Cochlear implants remain a safe procedure with a low complication rate. The majority of infections can be managed without removing the implant device. Advances in surgical technique and flap design have decreased the occurrence of wound-related complications. However, identification of risk factors for infection and optimization of treatment regimens will further reduce the complications associated with postoperative infection.

Adult↗

How does cochlear implantation affect the contralateral vestibular system?

Cochlear implantation has been performed for 16 years by investigators at Semmelweis University. During this period, different types of cochlear implants have been used and, in 30% of cases, hearing was observed to be restored in the nonimplanted ear. In addition to contralateral hearing improvement, significant improvement was observed in the caloric responsiveness of the nonoperated labyrinth. The preoperative median value of the average slow-phase velocity of the caloric test increased, and the increase was statistically significant on the contralateral side. The reason for this caloric response improvement is unclear, although possible explanations are brain plasticity or presently obscure trophic influence on the vestibular system. Whereas the role of brainstem function in the improvement of the contralateral ear's caloric response remains unclear it is also possible that hearing impulses affect the labyrinth. Clearly, the influence of cochlear implants on vestibular function requires further investigation to explain the improvement of contralateral vestibular responsiveness.

Adolescent↗

[Current developments in cochlear implantation].

Over the last 20 years, cochlear implantation has become a well accepted treatment in patients suffering from hearing loss or congenital deafness. Results have been impressive,and indications for a cochlear implant have been extended continuously. Thanks to a sophisticated diagnostic procedure, optimization of the surgical technique, and the progression of interdisciplinary cooperation in the field of rehabilitation, the acceptance of cochlear implantation is growing significantly. The manufacturers of the devices are making great efforts to miniaturize the external components of the system, and new developments in electrode arrays, combined with new speech coding strategies, result in better speech understanding. The new developments in electrode design, however, are not necessarily improvements over recent years. Nevertheless, a very well functioning network of physicians, scientists, and manufacturers has acted and reacted in an outstanding manner to identify possible causes of post-implantation meningitis, have taken immediate counter measures and presented possibilities of prevention.

Cochlear Implantation↗

Magnetic resonance imaging and cochlear implants: compatibility and safety aspects.

With cochlear implants, magnetic resonance imaging (MRI) has until recently been contraindicated due to excessive magnetic and electromagnetic interference. The aim of this study was to determine the MRI compatibility of the Med-E1 Combi 40/40+ cochlear implant, within a wide range of clinical MRI applications. In vitro experiments on a 1.5 T MR scanner were performed. Torque, force, demagnetization, artifacts, induced voltages, and temperature increase were measured in worst case scenarios for the implant. In addition, stabilization experiments were performed. It was shown that most of the electromagnetic interferences between the cochlear implant and the 1.5 T scanner remained within acceptable limits. One exception is the torque on the internal magnet, which represents a hazard for patients with these cochlear implants. Therefore, MRI examination should only be performed if there is a strong medical indication, and certainly some assessment of the relative risks involved versus the risk of not providing the diagnostic capabilities of MRI, will have to be made. Appropriate safety measures should be taken.

Artifacts↗

[Preoperative diagnostic procedures before cochlear implantation].

About 200 patients are considered each year for cochlear implant recipiency. Only 1/4 of these candidates actually receive an implant. The aim of the study is to discuss the preoperative procedure we use, which is aimed to exclude patients who would not benefit from an implant. A cochlear implant is an example of very expensive high-profile medical therapy, a single implant costing about 280,000 Austrian schillings. The aim of the preoperative diagnostic procedure is to select the right patients, with a view to providing the best audiologic outcome. During the past 20 years, important parameters have been identified to determine suitable patients. Candidates for a cochlear implant are infants and children (independent of the etiology of deafness or high-grade hearing loss), as well as postlingual deaf adults. Congenitally deaf adults or teenagers are considered unsuitable to receive an implant.

Acoustic Impedance Tests↗

Additive noise can enhance temporal coding in a computational model of analogue cochlear implant stimulation.

Conventional analogue multichannel cochlear implants are unlikely to convey formant information by the fine time structure of evoked discharges. Theoretically, however, the addition of noise to the channel outputs could enhance the representation of formants by time coding. In this study, the potential benefit of noise in analogue coding schemes was investigated using a computer model of cochlear implant stimulation. The cochlear nerve was modelled by the Frankenhauser-Huxley equations. For all five vowels investigated, the optimal addition of noise to the first channel of the simulated implant (200-671 Hz) caused enhancement of the first formant representation (as seen in amplitude spectra of the simulated discharges). For vowels with a low-frequency second formant, clear enhancement of the second formant resulted from the optimal addition of noise to the third channel (1200-2116 Hz). On the basis of the present computational study, additive noise would be expected to enhance the coding of temporal information by the discharges of a single nerve fiber.

Cochlear Implants↗

Clarion cochlear implant: short-term effects on voice parameters.

OBJECTIVE: This study aimed to evaluate the moment-to-moment auditory control of voice at an early stage after implantation with Clarion cochlear implants. STUDY DESIGN: A perceptive and electroacoustic evaluation of the voice was carried out through a digital analysis immediately after the activation of the implant, before the fitting procedure has begun. SETTING: The study was performed at the Department of Otolaryngology, University "La Sapienza" of Rome. PATIENTS: Nine profoundly deaf subjects (five post-linguistic deaf adults, two pre-linguistic deaf children and two peri-linguistic deaf subjects, one adult and one child). INTERVENTION: Surgical insertion of a Clarion cochlear device. MAIN OUTCOME MEASURES: Qualitative (short-term pitch and energy perturbation, intonation, vocal attack, quality, and intensity) and quantitative (F0, F1, F2 and F3 frequency values), under non activated (NAI) and activated (AI) condition, have been obtained. RESULTS: In the majority of patients, the perceptive evaluation under AI showed a lowering of voice intonation, a better control of voice intensity, and a reduction of nasal quality. These findings were confirmed by a significant lowering of F0 (Wicoxon non parametric test) in all cases and lowering of F1 and F2 in five cases. Additionally, a better definition of all formats in the majority of cases as well as by a parallelism of pitch and energy profile was observed. CONCLUSIONS: The Clarion cochlear implant device provided a recognizable moment-to-moment auditory control on voice and articulatory patterns. By monitoring the articulated voice during adjustment of the electrical stimulation at the first fitting session, one may be able to include these data and assist in the selection of the best rehabilitative strategy.

Adolescent↗

[The clinic application of multichannel cochlear implant with eleven cases reported].

OBJECTIVE: To review the effects of profound sensorineural deaf patients who were implanted multichannel cochlear. METHOD: Eleven profound deaf patients (6 prelingually deaf and 5 postlingually deaf) were implanted with twenty-two (model Minisystem 22) and twenty-four (model Nucleus 24) channel cochlear. Mapping of cochlear speech processor was done in 1 to 1.5 months after operation. RESULT: All of 11 patients obtained the hearing. The patients with postlingually deaf can dialog and communicate with telephone after a simple language training without lip reading training. These patients achieved the best results, they not only stepped in sound world but also obtained a normal living and work. In the prelingually deaf patients, they got hold of incoordinate progress in speech ability after assess and speech training. CONCLUSION: The multichannel cochlear implant had good effects in profound deaf patients, especial in postlingually deaf patients and younger children.

Adolescent↗

[First experiences in Neural Response Telemetry in patients with Nucleus 24 cochlear implant system].

Nucleus 24 Cochlear Implant System enables bidirectional communication with the implant-telemetry. Information about implant function can be obtained using telemetry. Neural Response Telemetry is a measurement of neural activity in the cochlea as a response to electrical stimulation. Principle of NRT recording, classification of responses and examples of responses obtained in patients implanted in Poznań are presented.

Adult↗