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At least 289 records · Page 16Linked to original sources
PubMed2000

Caries resistance in enamel by laser irradiation and topical fluoride treatment.

PURPOSE: The purpose of this in vitro study was to compare caries resistance of sound human enamel following argon laser (AL) irradiation, as well as, combinations of topical fluoride foams and AL irradiation. METHODS AND MATERIALS: Thirty extracted human teeth were sectioned into four buccal windows and assigned to one of the following treatment groups: (1) no treatment/control; (2) low fluence (11.5 J/cm2) AL irradiation for 10 seconds; (3) 1.23% APF foam for 4 minutes followed by low fluence AL irradiation; (4) 2.0% NaF foam for 4 minutes followed by low fluence AL irradiation. Caries-like lesions were created by submerging the teeth in ten Cate solution (pH 4.5). Following a 96-hour exposure period, 100 microns longitudinal sections were prepared for polarized light evaluation. Visilog 5.1.1. image analysis software was used to obtain quantitative lesion depths. The Scheffe F-test was used to compare the lesion depths for each of the four treatment groups. RESULTS: Lesion depths were: 16.1 +/- 6 microns for control; 13.7 +/- 4 microns for AL irradiation alone; 12.1 +/- 4.3 microns for 1.23% APF foam before AL irradiation; and 11.4 +/- 5.9 microns for 2.0% NaF foam before AL irradiation. Significant difference (p < 0.05) was found between the control group and the 2.0% NaF foam before AL irradiation group. AL irradiation alone reduced lesion depth by 15% compared with the control lesion. When AL irradiation was combined with 1.23% APF foam treatment, lesion depth decreased by 25% compared with control lesions, and by 29% when combined with 2.0% NaF foam. CONCLUSION: Combining AL irradiation and 2.0% NaF foam treatment significantly enhances the resistance of sound enamel to an in vitro cariogenic challenge.

Acidulated Phosphate Fluoride↗
PubMed2001

A community-based caries control program for pre-school children using topical fluorides: 18-month results.

Dental caries in Chinese pre-school children is common, and restorative treatment is not readily available. This prospective controlled clinical trial investigated the effectiveness of topical fluoride applications in arresting dentin caries. We divided 375 children (aged 3-5 yrs) with carious upper anterior teeth into five groups. Children in the first and second groups received annual applications of silver diamine fluoride solution (44,800 ppm F). NaF varnish (22,600 ppm F) was applied every three months onto the lesions of children in the third and fourth groups. For children in the first and third groups, soft carious tissues were removed prior to fluoride application. The fifth group was the control. We followed 341 children for 18 months. The mean numbers of new caries surfaces in the five groups were 0.4, 0.4, 0.8, 0.6, and 1.2, respectively (p = 0.001). The respective mean numbers of arrested carious tooth surfaces were 2.8, 3.0, 1.7, 1.5, and 1.0 (p < 0.001).

Analysis of Variance↗
PubMed1988

Retention of topical fluoride in the mouths of xerostomic subjects.

The total fluoride concentration in unstimulated whole saliva was measured before and at selected intervals after a self-applied 1.1% neutral NaF topical fluoride gel or use of a 0.05% neutral NaF fluoride mouthrinse in both normal individuals and patients with radiation-induced xerostomia. As expected, the gel resulted in higher peak fluoride values than the rinse and was retained in the mouth for longer periods of time in both groups. The xerostomic group expressed a mean oral fluoride concentration of 575 micrograms fluoride per gram of saliva within 1 min after the gel application and 150 micrograms/g following use of the mouthrinse, whereas the normal group exhibited peak concentrations of 112 and 71 micrograms/g, respectively, within 1 min after the same two treatments. The initial high levels of fluoride observed in normal subjects following the gel application decreased rapidly to less than 1 microgram/g within 2 h, whereas fluoride levels in the xerostomic subjects remained elevated above 12 micrograms/g for longer than 2 h. Similarly, following use of the mouthrinse, normal subjects' saliva fluoride levels decreased to less than 1 microgram/g within 1 h, whereas xerostomic subjects' saliva fluoride levels remained above 4 micrograms/g for longer than 2 h.

Adult↗
PubMed2003

Comparison of the effect of topical fluorides on the commercially available conventional glass ionomers, resin modified glass ionomers and polyacid modified composite resins--an in vitro study.

This study was undertaken to assess the effect of a single application of three professionally applied topical fluoride agents (Sodium fluoride 2%, Stannous fluoride 8% and APF 1.23%) on the surfaces of six modern esthetic restorative materials used in pediatric dentistry viz., two conventional glass ionomers (Fuji II and Shofu-restorative), two resin modified glass ionomers (Vitremer, with and without glaze, and Photac-fil Quick) and two Polyacid modified composite resins (Luxat and Hytac Aplitip). Mean surface roughness and surface micro hardness (SMH) measurements were the parameters employed for comparison. Results showed that APF gel applications significantly increased the surface roughness measurements and decreased SMH of all tested materials, which was pronounced in conventional glass ionomers when compared with resin modified glass ionomers and polyacid modified composite resins. NaF and SnF2 produced a statistically significant increase in the surface roughness of conventional glass ionomers without any significant change in surface roughness and SMH on rest of the materials tested, except for NaF on SMH values of Fuji II, which was statistically significant.

Acidulated Phosphate Fluoride↗
PubMed2005

Effect of topical fluoride application on toothbrushing abrasion of resin composites.

OBJECTIVES: This in vitro study assesses toothbrushing abrasion of a microfill (Heliomolar Radioopaque) and a hybrid composite (Herculite XRV) after application of two acidic fluoride agents. METHODS: Thirty-six specimens of each resin composite were fabricated, ground flat and polished. Subsequently the 36 samples of each material were evenly assigned to three groups. In the first group, samples were treated with the fluoride varnish Bifluorid 12 (5.5% F, pH 5.6), in the second group with Elmex Fluid (1.25% F, pH 4.3). In the third group, specimens remained unfluoridated (controls). After 8h, the samples were subjected to toothbrushing abrasion (2000 brushing strokes, load: 250 g) in an abrasive slurry. Fluoridation and brushing abrasion were repeated twice. Afterwards, abrasion of the materials was quantitatively determined with a laser profilometer and statistically analyzed (ANOVA). RESULTS AND SIGNIFICANCE: With Herculite both, Bifluorid 12 (P = 0.0001) and Elmex Fluid (P = 0.0001) led to a significant increase of brushing abrasion compared to the non-fluoridated group. However, no significant difference was observed between the two fluoridation regimes. Heliomolar showed a tendency towards higher abrasion after treatment with Elmex Fluid compared to Bifluorid 12 (P = 0.0496) and the non-fluoridated group (P = 0.0496), whereas treatment with Bifluorid 12 yielded no significant difference compared to the non-fluoridated Heliomolar specimens. Fluoridation of Herculite resulted in a 106-121% increase of abrasion, whereas Heliomolar only showed an increase by 5-30%. Application of the acidic fluoride products used led to an increase in toothbrushing abrasion of the tested composite restorative materials. However, clinical long-term studies are needed to determine the effect of topical fluoride regimes on resin composite materials.

Acrylic Resins↗
PubMed1979

Caries incidence in 7-9-year-old children after fissure sealing and topical fluoride therapy in Finland.

A total of 1345 elementary schoolchildren from grades 1-3 (aged 7-9 years) were examined and treated by community health center dentists during 1975-1977. The combined effect of fissure sealing and topical fluoride therapy with 2% NaF gel resulted over the 2 years in an increase in the proportion of caries-free permanent first molars from 50% to 81% in the 1st grade. The mean DMFS scored from the same teeth decreased from 2.8 to 0.8. In the age group born in 1968 the increment of new carious surfaces was 0.28 DFS/year with sealing and 1.13 DFS/year without.

Child↗
PubMedDate not supplied

The effectiveness of sponge-type intraoral applicators for applying topical fluorides in institutionalized older adults.

Many older adults who reside in nursing homes have disabilities which limit their capacity to benefit from the usual protocols for prevention of dental caries. This is a report of a study of the effectiveness of an alternative method of applying topical fluoride in the institutionalized elderly. Fluoride gel (1.1% NaF) was applied to the facial tooth surfaces of 10 elderly nursing home residents using a sponge-type intraoral applicator (IA). Subsequently, the same subjects rinsed with a commercial fluoride solution (0.05% NaF). Salivary fluoride levels were then assessed by the Taves (1968) method. The IA with fluoride produced significantly higher salivary fluoride levels over a period of three hours compared with rinsing.

Aged↗
PubMed1999

Evolution of professionally applied topical fluoride therapies.

Ever since researchers first realized the benefits of fluoride as an anticaries agent, they began investigating the effect of concentrated topical fluoride applications in reducing caries. Many forms of fluoride were studied, including solutions, gels or foams of sodium fluoride, stannous fluoride, organic amine fluoride, acidulated phosphate fluoride, and nonaqueous fluoride varnishes in an alcoholic solution of natural resins and difluorosilane agents covered by a polyurethane coating. All of these professionally applied topical agents have anticaries benefits, although these benefits and the ease of application vary. One trend that stands out in the evolution of professionally applied fluoride agents is the development of increasingly more user-friendly products.

Dental Caries↗
PubMed1989

[A clinical study on the effect of fluoride topical application by using of F-ion for caries prevention and desensitization of tooth].

The authors have studied on fluoride topical application effect clinically by using of fluoride ion applicator (F-ion) for the purpose of increasing dental caries prevention effect and desensitization efficiency of hypersensitive tooth. We have compared physical components of F-ion to Rivet ion and Pyocure which were made in Japan. And then, we have examined 40 extracted teeth applied 2% NaF solution with F-ion and calculated relative CaF2 production amounts by using of X-ray diffractometer after dividing total samples into 3 parts as control group, one time F-ion application group and 10 times F-ion application group. Otherwise, we have experimented 40 patients who have had hypersensitive teeth applying 10% SnF2 solution with the use of F-ion and found the patient's response for desensitization effects. The obtained results are as follows; 1. There were no obvious differences between F-ion fluoride applicator and other products, Rivet ion or Pyocure in aspect of physical components. 2. CaF2 production amounts were relatively higher in a group of one time 2% NaF application with the use of F-ion than those of control group as only fluoride solution applicated and it were the most in a group of 10 times fluoride application with the use of F-ion, through the examining by X-ray diffractometer, so it was estimated that F-ion technique of fluoride application would increase the fluoride penetration effect. 3. It was estimated that the desensitization effect for several application of 10% SnF2 solution with the use of F-ion would be recognized through the examination by Electro Pulp Tester and patient's response as 85.0% of desensitized persons. 4. The use of F-ion for increasing caries prevention and desensitization effect was recommended to dental clinics.

Clinical Trials as Topic↗
PubMed1981

Towards a rational approach to topical fluoride therapy at the mixed dentition stage.

Suggestions are given as to the means whereby the professional application of topical fluoride solutions at the mixed dentition stage can be rationalized. One requirement is that the objective of such therapy be clearly understood. Whilst the prevention of new caries lesions is an obvious aim, the importance of slowing or arresting existing early lesions should be appreciated. Data from clinical studies indicate that topical treatments should be directed at newly erupted teeth concentrating on sites with the highest caries susceptibility. At the mixed dentition stage much of the preventive effort must of necessity be directed at pits and fissures in permanent first molar teeth. A prolonged fluoride application (PFA) method provides one means of treating these sites in partially or fully erupted teeth.

Adolescent↗
PubMedDate not supplied

Systemic versus topical fluoride.

The actual mechanism of fluoride action is still a subject of debate. A dogma has existed for many decades, that fluoride has to be ingested and acts mainly pre-eruptively. However, recent studies concerning the systemic effect of fluoride supplementation concluded that the caries-preventive effect of fluoride is almost exclusively posteruptive. Moreover, epidemiologists have cast doubt on the validity of the 'old' studies dealing with fluoride use. The concept of the posteruptive fluoride effect is supported by in vitro and in situ investigations demonstrating that the mode of action of fluoride can be attributed mainly to its influence on de- and remineralization kinetics of dental hard tissues. Therefore, topical fluoride application (e.g. in the form of fluoridated dentifrices) should be encouraged. There are still important questions open that need to be answered despite existing knowledge about the caries-preventive effect of fluoride.

Administration, Oral↗
PubMed2003

Three restorative materials and topical fluoride gel used in xerostomic patients: a clinical comparison.

BACKGROUND: The authors compare the incidence of recurrent caries around two glass ionomer restorative materials and one amalgam material. METHODS: The authors placed 111 restorations in nine xerostomic patients. Patients were given oral hygiene instructions and fluoride gel to use daily. The authors evaluated the restorations clinically and with photographs and impressions at six months, one year and two years according to criteria for marginal adaptation, anatomical form, caries in adjacent tooth structure and caries at the cavosurface margin. The authors divided patients into users and nonusers of fluoride. RESULTS: At the two-year recall appointments, the authors evaluated 95 (86 percent) of the 111 restorations. They analyzed two-year data using an analysis of variance for repeated measures and Fisher's post hoc test. The study results showed no significant differences among materials in regard to caries at the cavosurface margin among fluoride users. However, among fluoride nonusers, patients with amalgam restorations had a significantly higher incidence of caries at the cavosurface margins than did patients with either of the two glass ionomer restorations. The authors found no statistically significant difference between restorations with regard to marginal integrity or anatomical form. However, one patient exhibited failure of glass ionomer restorations owing to material loss. CONCLUSIONS: Less caries developed at the margins of glass ionomer restorations compared with amalgam restorations in xerostomic patients who did not routinely use a neutral topical sodium fluoride gel. CLINICAL IMPLICATIONS: Fluoride-releasing materials may reduce caries surrounding restorations in high-risk patients who do not routinely use topical fluoride. Patients who routinely used topical fluoride gel did not develop recurrent caries, and clinicians should encourage the use of fluoride gel on a daily basis.

Analysis of Variance↗
PubMedDate not supplied

Prevention of artificial caries: effect of bonding agent, resin composite and topical fluoride application.

This study investigated the effect of fluoride containing resin composites and bonding agents, as well as the topical fluoride (F) application on the inhibition of artificial caries progression by using a pH-cycling model with alternating demineralizing (pH:4.5) and remineralizing (pH:7.0) solutions. Two bonding systems (F-containing bonding system [Reactmer Bond: RB] and non-F containing bonding system [Clearfil SE Bond: SE]), two resin composites, (F-containing [Reactmer Paste: RP] and non-F containing [Clearfil AP-X: AP]) were used. A combination of each bonding agent and a resin composite, RB+RP, RB+AP, SE+RP and SE+AP, was placed in 2 x 3 x 1.5-mm cavities on root dentin of extracted molars (n=96). Specimens were subjected to pH-cycling for 6 or 12 weeks. Half of all specimens were immersed in 0.05% NaF solution for 1 minute once a day as a topical F application. After the pH cycling period, a microradiograph of each specimen was taken, and the outer lesion depth of the artificial caries was measured by means of image analyzing software. The depths of the outer lesions at different periods were analyzed by one-way ANOVA and Sheffe's test at p=0.05. The combination that received F treatment showed reduced lesion depth compared to the same combination without F application. Except for the F application group of 12 weeks, there was no significant difference in lesion depth among each bonding and composite combination (p>0.05). At week 12 with the F application, RB+RP showed the shallowest lesion compared to the other combinations (p<0.05). The results indicated that the F application reduced the progression of artificial caries. Moreover, the combination of fluoride containing bonding agent and restorative material was the most effective for the inhibition of artificial caries progression based on the 12-week experimental period with topical F application.

Cariostatic Agents↗
PubMed1987

Clinical application of topical fluoride products--risks, benefits, and recommendations.

This portion of the symposium discusses the various methods of professionally applying high-concentration topical fluoride products and their risks and benefits. Numerous recent investigations in this area of research are reviewed and discussed. Data from these research investigations point to the need for care when high-potency F products are used, especially in young children. Oral-retained F doses following four-minute topical application procedures ranged from 10 to 31 mg when no suction devices or patient expectoration was utilized. Following the use of suctioning devices, oral-retained F doses ranged from 6 to 12 mg, a clinically unacceptable level. Following the use of suctioning devices plus patient expectoration, the oral-retained F doses were reduced to from 2 to 7.5 mg, depending on type of F product and application system. The following recommendation for topical application of high-potency F products are made: (1) No more than 2 g of gel per tray or approximately 40% of tray capacity should be dispensed. Even more conservative amounts should be considered for small children. (2) Because patients may have the need to swallow during a four-minute topical application procedure, the use of a saliva ejector during the procedure is recommended. (3) Following the four-minute application procedure, the patient should be instructed to expectorate thoroughly for from 30 sec to one min, regardless of whether high-speed suction is utilized. Expectoration is probably the single most effective way of reducing orally retained fluoride. (4) When utilizing custom individually fitted trays for patients requiring daily or weekly application of a high-F-concentration product, utilize only 5 to 10 drops of product per tray.

Absorption↗