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At least 289 records · Page 16Linked to original sources
PubMed1997

Effect of nebulizer configuration on delivery of aerosolized tobramycin.

Differences in the reported efficacy of aerosolized aminoglycosides may be due, in part, to differences in aerosol delivery. Optimization of delivery systems of bench testing of nebulizers in a manner that simulates clinical conditions can lead to enhanced lung deposition in subsequent clinical studies. In the present study, we assessed the effects of varying nebulizer configuration on the performance of ultrasonic and jet nebulizers. Tobramycin was mixed with a radiotracer (99mTc) to facilitate measurement of nebulizer output and particle size. A piston ventilator provided a simulated breathing pattern, and the dose delivered to a filter corresponded to what would have been inhaled by a patient (percentage of nebulizer charge inhaled). Particle size was measured using a cascade impactor, sampling at 1 L/min. An ultrasonic nebulizer (Ultra-Neb; DeVilbiss, Somerset, PA), ventilated at 20 breaths per minute, charged with 600 mg of tobramycin (in 30-mL volume) and fitted with its standard tubing, was tested with and without the addition of one-way valves to the inspiratory and expiratory ports of the mouthpiece. In order to assess the degree of environmental contamination associated with jet nebulizer therapy, a filter was placed at the expiratory port of all jet nebulizer experiments. The addition of the valves reduced the percentage of charge inhaled from a mean +/- standard deviation (SD) of 29.2% +/- 1.4% to 7.6% +/- 2.3% and reduced mass median aerodynamic diameter [MMAD (sigma g) from 4.3 microns (2.1) to 1.45 microns (1.65)]. A Circulaire (Westmed, Tucson, AZ) jet nebulizer (7 L/min flow, 50 pounds per square inch gauge (psig), 20 breaths per minute, containing 160 mg of tobramycin in a 4-mL volume) was tested in two configurations: using a plain T-piece and using a valved inflatable aerosol chamber. The use of the holding chamber resulted in an almost twofold reduction in MMAD [MMAD (sigma g) = 2.45 microns (2.0); T-piece; 1.25 microns (2.0), holding chamber]. A slight reduction in the percentage of nebulizer charge inhaled using the holding chamber, compared to the plain T-piece, was not statistically significant (mean +/- SD of percentage inhaled with holding chamber = 20.8% +/- 1.6%; with T-piece = 23.6% +/- 0.5%). With both the jet and ultrasonic nebulizers, breathing frequency influenced percentage inhaled, with a higher percentage inhaled at 20 breaths per minute compared to 15 breaths per minute. The use of the plain T-piece at 20 breaths per minute was associated with more environmental contamination than the use of the holding chamber with the same breathing pattern (26.7% +/- 1.0%, T-piece; 4.5% +/- 0.3%, holding chamber, P < 0.0001). We conclude that nebulizer configuration can potentially affect both the amount of aerosol inhaled and the particle size, and needs to be specified precisely in treatment protocols.

Administration, Inhalation↗
PubMed1991

Oral dysfunction in children with Down's syndrome: an evaluation of treatment effects by means of video registration.

The objects of the study were: (1) to analyse lip and tongue function in 24 children with Down's Syndrome as compared to an untreated control group of 19 healthy children; (2) to evaluate treatment effects of stimulation plates of the type Castillo Morales, in children with Downs' Syndrome. The range of the observation period during treatment was 4-11 months. Video recordings of 5 minutes (300 seconds) duration served as a basis for stop watch registrations of tongue protrusion and open mouth habit. Before treatment, the duration of tongue protrusion in the Downs' Syndrome group amounted to approximately half of the registration time as compared to an average of only 6.4 seconds in the control group. The values for lip closure differed only slightly. Following the insertion of the stimulation plate, the duration of tongue protrusion, in general, dropped markedly. No improvement in mouth closure or lip posture could be observed. A normalization of tongue function without the plate inserted was achieved after 4-11 months of treatment in 12 out of the 24 children. Follow-up registrations, ranging from 5 to 20 months, could be obtained in 7 out of the 12 successfully treated children. The results appeared to be stable in five of these children.

Child, Preschool↗
PubMed2004

Evaluation of protective equipment for prevention of injuries in rugby union.

BACKGROUND: Rugby union has a high rate of injury. The increased use of protective equipment may help mitigate these injuries. This study investigated the injury prevention effectiveness of the protective equipment used in rugby union. METHODS: A cohort of 304 rugby players in Dunedin, New Zealand was followed weekly during the 1993 club season to assess protective equipment use, participation in rugby, and injury outcomes. Generalized Poisson regression was used to model the rate of injury while adjusting for covariates such as level of competition, playing position, and injury history. RESULTS: The use of mouthguards appeared to lower the risk of orofacial injury [rate ratio (RR) = 0.56, 95% confidence interval (CI): 0.07-4.63], and padded headgear tended to prevent damage to the scalp and ears (RR = 0.59, 95% CI: 0.19-1.86). Support sleeves tended to reduce the risk of sprains and strains (RR = 0.58, 95% CI: 0.26-1.27). The risk of concussion was not lessened by the use of padded headgear (RR = 1.13, 95% CI: 0.40-3.16) or mouthguards (RR = 1.62, 95% CI: 0.51-5.11). There was no evidence of protective effects for any other equipment item (taping, shinguards, and grease). CONCLUSIONS: The protective equipment used in rugby union has limited effectiveness in preventing injuries. The results are supportive, however, of a role for mouthguards and padded headgear in preventing orofacial and scalp injuries, respectively, and for support sleeves in preventing sprains and strains.

Athletic Injuries↗
PubMed1991

A comparative study of treatments for positional sleep apnea.

Sixty male patients all with apnea plus hypopnea indices (A + HI) above 12.5, who met a criterion of positionality by having two or more times the rate of these events during supine sleep in comparison to their lateral sleep rate, were randomly assigned to one of four treatments for 8 weeks. All were restudied for two nights, one with and one without treatment devices. On treatment more than half the patients in each group reduced their A + HI to within normal limits and a third remained WNL without the use of devices. Half of those trained to sleep in the lateral position with the help of an alarm maintained this learning without the alarm as did half of those who were encouraged to learn this sleep posture on their own. There is an additive effect for the positional patient from wearing a tongue retaining device (TRD) if they continue to sleep in the supine position. Factors associated with successful treatment include overall severity, severity in the lateral position, weight, weight change, nasal patency and motivation to help their condition.

Behavior Therapy↗
PubMedDate not supplied

A tongue stent for prevention of oral trauma in the comatose patient.

This paper presents the need for and offers a solution to the problem of factitial tongue and other intra-oral injuries in comatose and decerebrate patients. The neurophysiology of jaw movement in the comatose patient is the basis for the design of an intraoral prosthesis which in two patients has prevented discoordinate mandibular chewing movements and facilitated healing of preexisting factitial lesions. The authors delineate in detail the fabrication, insertion, and maintenance of this protective prosthesis and emphasize the need for joint effort between the intensive care, neurosurgical, and oral surgical teams.

Adult↗
PubMed1999

Traumatic macroglossia: a life-threatening complication.

OBJECTIVE: To describe the use of muscle relaxants and a bite raiser to avoid continued tongue trauma. DESIGN: Case report. SETTING: A tertiary general intensive care unit (ICU). INTERVENTIONS: Muscle relaxation and bite raiser. MAIN RESULTS: Muscle relaxation and a bite raiser were used in a 17-yr-old male with traumatic macroglossia, which allowed for rapid resolution of edema and prevented additional trauma to the tongue. CONCLUSION: Early use of a bite raiser together with muscle relaxants allows for more rapid solution of edema and prevention of additional trauma to the tongue in patients with traumatic macroglossia.

Adolescent↗
PubMed1977

Management of dental trauma in children and adolescents.

The emergency treatment of dental trauma has traditionally been handled in the emergency rooms of medical centers, or in the dental office. With increasing emphasis on comprehensive medical care, and the tendency of more recent graduates to locate in rural areas, there is a growing trend for physicians to be involved in providing emergency care for traumatic injuries to the dental and oral tissues. The authors discuss the etiology of dental trauma and the highly psychologic impact of such injuries upon the patient and parents. Techniques for prevention and a comprehensive plan are outlined for systematic history taking and examination. A classification of eight levels of dental injuries (5), techniques for the emergency, and subsequent restorative care are given. Emphasis is placed upon immediate care which can, if necessary, be provided by the physician pending referral to a dentist.

Child↗
PubMed1997

Minimally invasive head holder to improve the performance of frameless stereotactic surgery.

Frameless stereotactic procedures crucially depend on the firmness of immobilization. Once registered, shifting of the patient leads to inaccuracy, and the patient registration has to be realigned. To overcome the drawbacks of conventional invasive fixation for neurosurgery and the widely accepted fixation with surgical tape in ENT, the Vogele-Bale-Hohner (VBH) head holder has been developed. It permits rigid, noninvasive fixation of the head by using an individualized dental cast attached to the upper jaw by vacuum. Oral intubation is uncomplicated. In addition, a special registration device providing well defined reference points can be mounted to the mouthpiece. We report the first promising clinical applications of this device.

Adenocarcinoma↗
PubMed2000

Influence of intra-oral maxillary sports mouthguards on the airflow dynamics of oral breathing.

PURPOSE: Mouthguards worn during sporting competition may influence oral airway flow dynamics and potentially increase airflow resistance during mouth breathing. METHODS: We measured oral airflow resistance (RO) in 10 normal subjects (four men, six women, age 29 +/- 3 yr, mean +/- SEM) wearing two different custom-made maxillary mouthguards. RESULTS: During tidal mouthpiece breathing (jaw position controlled), inspiratory R(O) (at (1.4 L x s(-1)) increased from 0.22 (0.15-0.46) cm H2O x L(-1) x s(-1) (median and interquartile range) to 0.47 (0.24-0.52) cm H2O x L(-1) x s(-1) with mouthguard 1 (general sports mouthguard) and from 0.34 (0.27-0.51) to 0.46 (0.39-0.86) cm H2O x L(-1) x s(-1) (N = 8) with mouthguard 2 (laminated, field hockey mouthguard, both P < 0.05). With oral only mask breathing (jaw position not controlled), inspiratory R(O) (at 0.4 L x s(-1)) increased to 1.02 (0.42-1.57) cm H2O x L(-1) x s(-1) (P < 0.03, compared with mouthpiece) but was variably affected by both mouthguards. At 1.0 L x s(-1), there was a tendency for both mouthguards to increase inspiratory R(O); however, this effect only reached significance for mouthguard 1 during mouthpiece breathing. CONCLUSION: Thus, although maxillary mouthguards do increase R(O) when jaw position is controlled, individual subjects respond differently when in control of mouth opening. This may be related to variable recruitment of compensatory mechanisms (e.g. mouth opening and/or oral airway dilator muscle activity).

Adult↗
PubMed2001

Use of protective equipment in a cohort of rugby players.

PURPOSE: To describe the level of usage of protective devices and equipment in a cohort of New Zealand rugby players. METHODS: Male and female players (N = 327) from a range of competitive grades were followed over the course of the season. Participants were interviewed weekly about their participation in rugby and use of protective equipment. The main outcome measure was percentage of all player-weeks of follow-up for which each equipment item was used. RESULTS: Mouthguards, the most commonly used equipment item, were worn for 64.9% of player-weeks. Mouthguard usage ranged from 55.0% of player-weeks in Schoolgirls grade to 72.9% of player-weeks in Senior A competition. The next most common item was taping of body joints (23.7% of player-weeks). The sites most commonly taped were the ankle, knee, and hand. Overall usage for the other protective equipment items studied (shin guards, padded headgear, head tape, support sleeves, and grease) was below 15%. In general, forwards had higher usage of protective equipment than backs, and male players had higher usage than female players. The most common self-reported reasons for using protective equipment were to prevent injury and because of a past injury. Players exhibited considerable week-to-week variation in their usage of protective equipment. CONCLUSIONS: In general, equipment usage was highest in those at greatest risk of injury, namely, forwards, male players, and the senior grades. The high voluntary use of mouthguards is encouraging and indicative of a base of player support for their role in this sport.

Adolescent↗
PubMed2002

Effect of mouthguards on dental injuries and concussions in college basketball.

PURPOSE: Dental injuries can be permanent and disfiguring. They are also universally expensive to treat. Many dentists, sports physicians, and athletic trainers recommend mouthguards for athletes participating in certain competitive sports, including men's college basketball, because of a common perception that mouthguards afford protection from dental injuries, and even some concussions. However, there are few reliable reports of the incidence of dental injuries and concussions in men's college basketball, and good evidence that mouthguards reduce the risk of these injuries in this population of athletes is notably lacking. This study prospectively recorded dental injuries and concussions among 50 men's Division I college basketball teams during one competitive season, then compared injury rates between mouthguard users and nonusers. METHODS: During the 1999 to 2000 basketball season, athletic trainers from 50 men's Division I college basketball programs used an Internet Web site to submit weekly reports of the number of athlete exposures, mouthguard users, concussions, oral soft tissue injuries, dental injuries, and dentist referrals. RESULTS: Response rate was 86%. There were 70,936 athlete exposures. Athletes using custom-fitted mouthguards accounted for 8663 exposures. Injury rates were expressed as number of injuries per 1000 athlete exposures. There were no significant differences between mouthguard users and nonusers in rates of concussions (0.35 vs 0.55) or oral soft tissue injuries (0.69 vs 1.06). Mouthguard users had significantly lower rates of dental injuries (0.12 vs 0.67; P < 0.05) and dentist referrals (0.00 vs 0.72; P < 0.05) than nonusers. CONCLUSION: Custom-fitted mouthguards do not significantly affect rates of concussions or oral soft tissue injuries, but can significantly reduce the morbidity and expense resulting from dental injuries in men's Division I college basketball.

Athletic Injuries↗
PubMed2002

The effect of mouthguard design on stresses in the tooth-bone complex.

PURPOSE: Mouthguards protect the tooth-bone complex from impact loads that occur during sporting activity. The aim of this study is to investigate the effects of varying mouthguard thickness and stiffness on the magnitude of tensile stresses in the tooth-bone-complex. METHODS: A two-dimensional, plane stress, finite element representation of a central maxillary incisor (CMI) is created. For validation purposes, displacements of the incisal edge of the unprotected tooth model are compared with in vivo displacements under similar loads. A protective mouthguard is then superimposed over the model with varied labial thickness (1-6 mm) and stiffness (9-900MPa) representing a range of designs available. A large horizontal static load of 500N is then applied to the anterior surface of the mouthguard and the resulting stresses in the tooth-bone complex are presented. It is suggested that this loading condition most accurately represent the situation occurring when a guarded tooth collides with a soft object (e.g. boxing glove). RESULTS: It is generally found that mouthguard thickness and stiffness are both desirable in terms of reducing stresses. However, the protection offered by the low-stiffness guards, regardless of thickness, is minimal. Since this low-stiffness (9MPa) is representative of the most common choice of material in mouthguard fabrication, such findings may cast doubt on the ability of popular mouthguards to redistribute stress. CONCLUSION: While few would disagree that these low-stiffness guards absorb shock during hard-object collisions (e.g. baseballs), they may not protect the tooth-bone during soft-object collisions (e.g. boxing gloves). In order to optimize their protective capabilities for a range of loads, the range of materials used in mouthguard construction may have to be reconsidered.

Equipment Design↗
PubMedDate not supplied

A thirty-year review of oral appliances used to manage microstomia, 1972 to 2002.

Patients who have sustained a facial burn often contend with cosmetic and functional challenges, including microstomia. Many devices have been created by a variety of professionals to provide oral stretching. These devices can be classified as intraoral or extraoral and deliver a stretch either horizontally, vertically, or circumorally. The purpose of this article is to present a comprehensive review of oral-stretching devices.

Burns↗
PubMed2005

Effect of noncustom bimolar mouthguards on peak ventilation in ice hockey players.

OBJECTIVE: To examine the effect of a noncustom bimolar mouthguard on ventilation in female varsity ice hockey players. DESIGN: Prospective crossover study. MAIN OUTCOME MEASURES: Expired ventilation (VE), oxygen uptake (VO2), and heart rate were measured in 12 university varsity female ice hockey players while these players were skating on a skating treadmill. Data were collected for each player with and without a mouthguard at both submaximal and maximal efforts to recreate the intensity of games. RESULTS: VE and VO2 were similar (P > 0.05) with and without a noncustom bimolar mouthguard at submaximal effort. The mean VE at maximal effort (VEmax) was significantly lower (P < 0.05) using the mouthguard (108.5 l/min) compared with without a mouthguard (114.1 l/min). VO2 at maximal effort (VO2max) was significantly lower (P < 0.05) using the mouthguard (48.8 mL.kg.min) compared with without a mouthguard (52.4 mL.kg.min). Heart rates were similar for players with and without a mouthguard at both submaximal and maximal efforts. CONCLUSIONS: Noncustom bimolar mouthguards may reduce ventilation and oxygen uptake at maximal efforts by female ice hockey players.

Adult↗
PubMed2005

Comparison of mouth guard designs and concussion prevention in contact sports: a multicenter randomized controlled trial.

OBJECTIVES: To compare the effectiveness of the WIPSS mouth guard to other currently used mouth guards in the prevention of concussion injuries in athletes participating in varsity football and rugby. DESIGN: : Multicenter, cluster-randomized, controlled trial comparing the WIPSS Brain-Pad mouth guard against the standard use mouth guard of choice. Teams were monitored by their respective athletic therapist, trainer, or sports physician for 1 playing season to diagnose and record incident concussion injuries and dental trauma. Concussion symptoms were also recorded at the time of injury. SETTING: Five Ontario universities. PARTICIPANTS: University male football (394) and university male (129) and female (123) rugby athletes reporting to 2003 fall training camps. MAIN OUTCOME MEASUREMENTS: The primary end point was the incidence of any diagnosed concussion events during the 2003 playing season as defined by the American Academy of Neurology Concussion Guidelines. Secondary endpoints included the incidence of dental trauma events and observed concussion symptoms. RESULTS: There was no significant difference in the number of concussions observed between the intervention and control arms of this trial (P = 0.79; odds ratio, 1.06, in favor of controls; 95% CI, 0.51, <<1.61). No dental trauma events occurred. The 5 most common symptoms experienced by concussed athletes were dizziness, general headache, nausea, loss of visual focus, and personality changes. CONCLUSIONS: In this study, concussion rates were not significantly different for varsity football and rugby players who wore the WIPSS Brain-Pad mouth guard compared with other types of mouth guards.

Adolescent↗