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At least 289 records · Page 16Linked to original sources
PubMed1999

[Exophthalmos and blindness disclosing an ethmoidal-maxillary malignant non-Hodgkin's T-cell lymphoma. Apropos of a case].

BACKGROUND: We report a case of non-Hodgkin's malignant lymphoma of the cervicofacial region revealed by unilateral exophthalmos and blindness, an unusual mode of expression. CASE REPORT: A 40-year-old man with a 4-month history of diabetes mellitus had suffered from exophthalmos and blindness of the right eye for 20 years. Physical examination showed a homolateral hemifacial tumefaction and ophthalmoplegia. The right ocular fundus showed papillar edema and non-proliferative diabetic retinopathy. The left eye was normal. The otolaryngology explorations revealed a voluminous tumor in the anterior nasal cavity and in the cavum. Two biopsies were performed. Histology reported non-Hodgkin's T-cell lymphoma. Orbitocerebral and cervicofacial computed tomography visualized the aggressive ethmoidomaxillary extension with intraorbital and intracranial involvement. Chemotherapy (CHOP) combined with radiotherapy led to tumor regression and involution of the exophthalmos. Diagnostic difficulties, management and prognosis are discussed.

Adult↗
PubMed1997

[Photographic diagnosis for common intraorbital tumors].

OBJECTIVE: To compare and analyze the modern photographic methods used for localization and analysis of the nature of intraorbital tumors. METHODS: B-scan, CT scan and magnetic resonance imaging (MRI) were used to examine six types of common intraorbital tumor (20 cases for each type). RESULTS: Each method can locate and show the nature of the lesions, and B-scan has a better value to display internal structure and dynamics of orbital lesions. CT can discover the lesions and exactly show their locations, while MRI is more valuable to display the optic nerve tumor and the extension of intraorbital tumor to extraorbital regions. CONCLUSIONS: All the above methods can locate and show the nature of intraorbital tumors, and each has its own special defects and advantages which can be complementary to one another.

Dermoid Cyst↗
PubMed1975

[Treatment of tumors of some structures of the splanchocranium].

The results of long experience with many methods of reconstructive surgery following destruction of various splanchnocranial structures are presented. Emphasis is placed on the usefulness of cooperation between the oncological and plastic surgeon. Fifteen cases are illustrated. In many of these, endoarterial infusion of chemical antiblastics was first employed. Since tumours may vary considerably in site and histological type, as well in the biotype, age and sex of the patient, and since a variety of radical and reconstructive techniques exist for individual or associated use, therapeutical programmes cannot be put forward with any degree of confidence, but must obviously be determined by the surgeon's personal experience.

Adult↗
PubMed1975

[Prosthetic problems after excisional surgery].

The authors present a few cases maxillary and facial reconstruction with restoration of the esthetic appearance, mastication and phonation, using the obturator muscles and prostheses made up of acrylic resin and silicone elastomers.

Acrylic Resins↗
PubMed1999

[A case of orbital lymphoproliferative lesion diagnosed as malignant lymphoma after recurring 11 years later].

BACKGROUND: Most primary lymphoproliferative lesions in the ocular adnexa, including the eyelid, conjunctiva, and orbit, are diagnosed as low-grade malignant lymphomas. Recurrence and dissemination of these tumors are rare in Japan. The long-term prognosis for this disorder still remains to be clarified. CASE AND METHOD: A 53-year-old woman was first referred to us for right orbital tumor in 1986. After subtotal resection of the tumor, the patient received no additional treatment. She visited us in 1997 with the complaint of bilateral orbital tumor. Biopsied specimens were examined histologically using hematoxylin-eosine and immunohistological staining. Southern blot hybridization was used to detect immunoglobulin gene rearrangement. The paraffin-embedded specimen obtained in 1986 was also examined for immunoglobulin gene rearrangement using nested polymerase chain reaction technique. FINDINGS: The specimens from 1997 and 1986 were both diagnosed as lymphoid type of inflammatory pseudotumor, based on polyclonal B cell immunohistological staining. Immunoglobulin gene rearrangement was present in both specimens. CONCLUSION: The orbital tumor resected in 1986 was a low-grade malignant lymphoma which disseminated systemically 11 years later. This case shows a long-term course of orbital lymphoproliferative lesion with positive immunoglobulin gene rearrangement. It also shows the importance of follow-up over 10 years in the case of low-grade malignant lymphoma of the ocular adnexa.

Diagnosis, Differential↗
PubMedDate not supplied

Clinical trials with 1-acetyl-2-picolinoylhydrazine (NSC-68626) in children.

Thirty-seven children with various malignant neoplasms were treated with 1-acetyl-2-picolinoylhydrazine. Complete regressions were documented in one child with embryonal rhabdomyosarcoma, in one child with generalized histiocytosis-X, and in one child with Hodgkin's disease. One patient had renal failure while receiving the drug but no conclusive cause and effect relationship could be established. Toxic effects otherwise were mild and consisted primarily of nausea and vomiting.

Adolescent↗
PubMedDate not supplied

[Personal modification of the Codubix prosthesis in craniofacial plastic surgery].

Typical "Codubix" prosthesis usually applied to cover cranial defect was used in craniofacial reconstruction. In this case the defect resulted from total removal of cranial basis neoplasm infiltrating orbital roof and surrounding structures. The cranial defect included right frontal bone--superciliary arch, orbital roof and margin; zygomatic bone frontal part junction and the lesser and greater wings of the sphenoid. Cranial reconstruction in this spatially differentiated area is technically difficult. The authors discuss the way of standard prosthesis modification in order to apply it in craniofacial reconstruction. Follow-up radiological and aesthetic results are presented.

Bone Plates↗
PubMed1975

[Problems of intracranial extension of malignant disease of the nose and sinuses (author's transl)].

Out of 424 cancers of the nasal cavities or sinuses seen at the University E.N.T. Clinic Jena, 120 had penetrated into the anterior or middle cranial fossa. The commonest of these were tumours of the upper sinuses but a fifth of all antral tumours were also involved. The favourite site of intracranial breakthrough was studied in relation to the origin of the tumour and a particular liability of antral cancers to extend to the middle cranial fossa was noted. Critical analysis of the preoperative diagnostic features showed that the extent of the tumour relative to the base of the skull was often only demonstrated by a wide external surgical exposure. Operative and electrosurgical exenteration after Zange followed by radium application to the infiltrated dura resulted in over 17% of the operated patients surviving 5 years or more without recurrences. Irradiation alone was unsuccessful in all cases. In recent years resection of the tumour has been followed by excision of the infiltrated segment of the dura and the defect covered with fascia lata. First impressions and several examples are given.

Adult↗