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Use of antibiotics for preterm premature rupture of membranes. Rationales and results.

PPROM is directly associated with 30% to 40% of preterm births. Reproductive tract infection, inflammation, or both may be primary causes or occur secondarily after PPROM and hasten the onset of labor. Recent carefully controlled trials demonstrate that antibiotic treatment (erythromycin, ampicillin) can significantly lengthen the "beneficial latency period" and reduce perinatal and maternal morbidity, as well as the costs.

Anti-Bacterial Agents↗

[The female condom].

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Contraceptive Devices, Female↗

Breeding soundness examination of yearling beef bulls.

Yearling beef bulls were subjected to a breeding soundness examination (BSE) at completion of performance testing programs at 4 locations over 5 years. Of 862 bulls, 80.1% were classified as satisfactory potential breeders, 7.3% as questionable potential breeders, and 12.7% as unsatisfactory potential breeders. Year (P less than 0.01), location (P less than 0.01), and breed (P less than 0.01) affected the percentage of bulls classified as satisfactory; age of the bulls did not affect this percentage. Adjusted mean scrotal circumference (SC) measurements were 31, 33.2, and 34.8 cm for bulls classified as unsatisfactory, questionable, and satisfactory (P less than 0.01), respectively. Of 109 bulls classified as unsatisfactory, 2.8% were so classified because of poor semen quality alone; 41.3% had no ejaculate in 4 separate electroejaculation attempts. Other abnormalities in these 109 bulls included reproductive tract infections (22%), persistent penile frenulum (16.5%), testicular abnormalities (8.3%), fibropapilloma (1.8%), hernia (1.8%), aplastic epididymis (1.8%), penile abnormalities (1.8%), pendulous sheath (0.9%), and eye abnormalities (0.9%). Age had a significant effect on SC in bulls at 3 locations and on percentage of normal cells, primary abnormalities, and secondary abnormalities as well as BSE score at 1 location. Percentage of primary and secondary abnormalities as well as SC were different across years at 2 locations, and percentage of normal and motile cells as well as BSE score were different across years at 1 location. Breed effects were significant for SC, percentage of primary abnormalities, and BSE score at 3 locations and for percentage of normal and motile cells at 1 location.

Animals↗

[Infection hazards and complications following the use of IUDs].

Own experiences on IUD-complications especially irregular bleedings and infections underline that modern plastic intrauterine devices are second-rate contraceptives. Compared to hormonal contraceptive drugs intrauterine devices have a higher pregnancy risk and increased rates of infections. Therefore the IUD is in our opinion not suited primary contraceptive method used without indication. Because of the relatively often occurring ascendant genital infections the application of intrauterine devices should not be carried out in nulliparae.

Adult↗

Venereal disease prevention.

Outlining his interest and work in the prevention of VD, especially gonorrhea and syphilis, the author addresses the questions of prophylaxis and contraceptives, together with their technological advances, and ties these two concepts into the complex fabric of human behavior, history of available therapy in both world wars as well as the economic, social, moral and national concepts of what constitutes proper emphasis: prevention or cure. Thus, the absence of therapeutic modalities spurred the United States Armed Services to utilize Credé's solution for urethral irrigation and locally applied calomel ointment for prophylactic purposes in World War I but abandoned this mode when cheap penicillin therapy became available after World War II. Similarly, the utilization of combined prophylactic and contraceptive methods for women has to await the overcoming of societal and parental resistance. Particularly where teenagers are concerned the importance of combined modalities is stressed.

Adolescent↗