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Results for “Respiratory Function Tests”

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At least 289 records · Page 16Linked to original sources
PubMed1994

[Respiratory function tests as a predictive indicator of postoperative course in patients undergoing pneumonectomy because of neoplasms].

Postoperative morbidity and mortality were correlated with the preoperative results of three widely used pulmonary function tests (FVC, FEV1, FEV1/FVC) in 100 consecutive patients who underwent pneumonectomy for lung carcinoma. Factor analyzed following operation included thirty-day mortality, incidence of cardiovascular and respiratory complications, number of individuals requiring prolonged mechanical ventilation. Nineteen patients had a forced vital capacity (FVC) of 70% or less of the normal value, seven had a one-second forced expiratory volume (FEV1) of 1.5 liters or less, and thirty-three had a FEV1 of less than 2 liters. Fourteen patients had a FEV1/FVC ratio of 65% or less. There were no differences in morbidity or mortality between these patients and those presenting higher test scores. As a general rule, decisions regarding operability and extent of resection cannot be made solely on the basis of the three spirometry tests reviewed.

Adult↗
PubMedDate not supplied

CT and functional respiratory tests. Evaluation of efficacy of bronchodilator therapy in chronic obstructive pulmonary disease (COPD).

PURPOSE: To evaluate changes in qualitative and quantitative parameters at high resolution CT (HRCT) and in respiratory function indexes (RFI) after bronchodilator administration in COPD patients. MATERIALS AND METHODS: Fifteen former smokers (9 male and 6 female, mean age 65 years), with COPD were studied. Patients with asthmatic or pulmonary diseases were excluded. After informed consent, the patients underwent blood gas analysis, baseline RFI (respiratory function index), inspiratory/expiratory HRCT, administration of salbutamol and bromide (by metered-dose inhaler), RFI after 45 minutes, and inspiratory/expiratory HRCT. First, we performed a visual qualitative analysis (by means of a preformed questionnaire), and then a quantitative analysis by "density mask" programme at three levels: aortic arch, carina, and supradiaphragmatic level. By using this diagnostic approach we were able to determined the global area of each lung, dependent and independent of density, bronchus-artery ratio, emphysema extension, air trapping, morphologic distortion of the airways. RESULTS: Data correlation analysed through linear regression statistical test. Outstanding correlations were found between the RFI (Raw, SVC, IC, RV, FEV1, VP70) and, respectively, density, global lung areas, and bronchus-artery ratio changes before and after bronchodilators administration. CONCLUSIONS: Our study confirmed the usefulness of bronchodilators and the need for a multiparametric and comparative (radiological and functional) approach to COPD, as well as the usefulness of HRCT in evaluating the response to visible airway physiologic stimulus and extension, and reversibility of air trapping.

Aged↗
PubMedDate not supplied

[Long term results of treatment with cytostatic drugs on respiratory function tests in children].

In 47 children after a 5 year remission of treated acute lymphoblastic leukemia respiratory function was assessed. In 11 a decrease of VC was found, while in 12 signs of obturation of lower airways were present. These results imply the presence of restrictive changes suggesting an interstitial lung disease. These children are at risk of developing a chronic pneumopathy.

Adolescent↗
PubMed1986

A longitudinal study of symptoms and respiratory function tests in iron miners.

A first survey has been conducted on 1179 iron-ore mine workers, 35-55 years old, who were randomly selected from 5900 at work with normal chest roentgenograms. Five years later, 871 of them were re-examined. Both surveys included a standard respiratory symptoms questionnaire (British MRC), a physical examination of the chest, and measurement of pulmonary function (vital capacity - VC; forced expiratory volume during 1 s - FEV1.0; residual volume - R.V. by helium dilution: carbon monoxide uptake - FuCO by the steady-state method). Both surveys were done by the same research team under identical conditions, using the same equipment. The mine technical services determined the dust and noxious gas concentrations at work places. No evidence of worsening of respiratory health status was observed overall. Symptoms of chronic bronchitis and asthma were recorded with a similar prevalence in both surveys; the decline in lung function was minimal for the total sample. However, our aim was to compare changes that were observed in groups differing by work place (surface or underground) or by activity (active or retired). Analysis showed that development of respiratory symptoms was more frequent and decline in lung function accelerated in the 5-year interval among underground workers who were still active as compared to those retired. In all subgroups (surface or underground workers, active or retired), decline of lung function values was more marked in smokers compared to non-smokers.

Adult↗