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Intermittent urinary retention secondary to a uterine leiomyoma.

Urinary retention rarely affects reproductive-age women. In obstructive retention, the source must be determined and then removed to allow the patient to void normally. The most common causes of obstructive retention are gynecologic surgery and pelvic masses. Two women with intermittent urinary retention were evaluated in our clinic. Case 1 was a 48-year-old patient who voided frequently to avoid urinary retention. She had an ultrasound showing a large posterior leiomyoma. Case 2 was a 49-year-old female who presented with urinary retention during her menses. Magnetic resonance imaging result showed a large posterior leiomyoma deflecting the cervix anteriorly. Both women's urinary retention completely resolved after a total abdominal hysterectomy. Uterine leiomyomas may be the cause of urinary retention in reproductive-age females without other etiologies.

Female↗

Parietal cortex lesions do not impair retention performance of rats in a 14-unit T-maze unless hippocampal damage is present.

Young male F-344 rats, pretrained in a straight runway to avoid shock, were then trained in a shock-motivated 14-unit T-maze. One day after maze acquisition, extensive parietal cortex lesions (PC) or sham operations (CON) were performed to assess possible involvement of parietal cortex in the age-related impairment previously observed in this task. Twelve days after surgery, a first 10-trial retention session in the 14-unit T-maze was conducted. One day later the vibrissae of half the rats in each group were clipped to examine involvement of the damaged barrel cortex field in maze performance of rats with PC lesions. The following day a second 10-trial retention session occurred. Finally, retention of the straight runway avoidance response was tested. Histological verification revealed a group with consistent parietal damage but also a subgroup with relatively small lesions to dorsal or lateral hippocampus in addition to parietal damage (PC + HIP). Behavioral results revealed virtually perfect maze retention for CON and PC rats. In contrast, PC + HIP rats were severely impaired in maze retention performance. Retention of the straight runway avoidance response was perfect in CON and PC rats but was impaired in PC + HIP rats. Vibrissae clipping did not affect error performance in the maze but led to a transitory increase in runtime. Overall, the results indicate that parietal lobe damage shortly after acquisition does not impair retention performance of young rats in the 14-unit T-maze, unless hippocampal damage is also evident. Thus, parietal lobe dysfunction alone would not appear to be involved in the age-related retention impairment previously observed in this task.

Aging↗

Acute urinary retention after transperineal template-guided prostate biopsy.

PURPOSE: Urinary retention occurs in 5%-36% of patients with prostate cancer after implantation of radioactive seeds for brachytherapy. We used transperineal biopsy as a model to determine the influence of needle trauma on urinary retention. METHODS AND MATERIAL: We retrospectively reviewed medical records of 157 men with high risk of prostate cancer who underwent systematic ultrasound-guided biopsy of the prostate with the transperineal template technique and an 18-gauge automated biopsy device. RESULTS: Eighteen of 157 patients (11.5%; 95% confidence interval, 6.9%-17.5%) had urinary retention within 48 hours after biopsy. Median age was 68.5 years in patients with retention vs. 67.0 years in patients without (p = 0.319); median calculated prostate volume, 76.5 vs. 51.5 mL (p = 0.015); and median number of biopsy cores, 22.0 vs. 20.0 (p = 0.038). Age distribution differed between groups (p = 0.047), with more younger men in the no-retention group. On multivariate analysis, only number of biopsy cores significantly predicted urinary retention (p = 0.003). Four patients required transurethral resection; 1 had an indwelling catheter until radical prostatectomy; and 13 were catheter-free within 1-5 days. CONCLUSIONS: Needle trauma alone may cause urinary retention in men undergoing transperineal procedures. The number of needle incursions and prostate size are predictors of postprocedure urinary retention.

Acute Disease↗

In vitro assessment of retention of four esthetic dowels to resin core foundation and teeth.

STATEMENT OF PROBLEM: Several new esthetic dowel systems are currently available for the restoration of endodontically treated teeth. These dowel systems enhance the esthetic quality of all-ceramic restorations better than metallic dowel systems. PURPOSE: The purpose of this study was to evaluate the retentive strength of composite and ceramic endodontic dowel systems to the tooth and to the core foundation. MATERIAL AND METHODS: The following dowel systems were tested: resin dowels (Fibrekor [FR]; Luscent [LU]; Twin Luscent Anchor [TLU]); ceramic dowels (Cerapost [CR]; Cosmopost [CO]); and a titanium dowel (ParaPost XH [Ti]). In Part I of the study, core retention was tested by forming Bis-Core resin (n=12) cores around dowels followed by separation using a universal testing machine. In Part II, 60 (n=12) extracted human canines were endodontically treated, and dowel spaces were prepared using the corresponding drill for each dowel system. Nine-millimeter resin and ceramic dowels were cemented with C & B resin luting agent. Additionally, 2 groups (n=12) of Ti dowels cemented with C & B resin luting agent and zinc phosphate luting agent served as control groups. Retention was tested using a universal testing machine to separate the dowels from teeth. One-way analysis of variance and Student Newman-Keuls tests were conducted for statistical analysis (alpha=.05). Surface texture of all dowel systems tested was examined using SEM at original magnification x25 and x250. RESULTS: Core retention of Ti was higher than all esthetic dowels tested (alpha<.05), but FR had higher core retention than the other esthetic dowels tested. Resin dowels had better retention to teeth than ceramic dowels (alpha<.05). CONCLUSION: The esthetic dowel systems were less retentive for the resin core material than the titanium control. Resin dowel systems were more retentive in the root than the ceramic dowels but were similar to the titanium control.

Analysis of Variance↗

Overdenture retention of four resilient liners over an implant bar.

STATEMENT OF PROBLEM: Resilient denture liners offer an alternative method of designing implant-retained overdentures. Space is provided in the overdenture to envelop the implant bar with a resilient liner to be applied chairside or processed in the laboratory. The degree of retention may vary and these materials change over time. PURPOSE: This study evaluated the retention on an implant/bar prosthesis with overdentures lined with 4 resilient denture lining materials, after cyclic insertion and removal over a simulated 1.5-year period. MATERIAL AND METHODS: Four implants were placed in a mandibular edentulous cast and a gold bar superstructure was made. Overdentures were processed in Lucitone-199 and Tokuyama, Luci-Sof, Molloplast-B, and PermaSoft (with and without sealer) lining materials, cured according to manufacturers' instructions. Each of 5 overdentures contained each liner and were cycled 2740 times (simulating 1.5 years of service at 5 insertions daily) in 37 degrees C water in an Instron at 20 cm/min. Insertion and retention force were measured. RESULTS: The 3 silicone rubber liners were 3 to 5 times more retentive than the plasticized acrylic liner initially. After cycling, Tokuyama soft liner (autopolymerized silicone) gained 14% retention, Luci-Sof (heat-cured silicone) gained 8%, Molloplast-B (heat-cured silicone) lost 12%, whereas PermaSoft (autopolymerized plasticized acrylic) with sealer lost 43%, and without sealer lost 60%. PermaSoft lining material also chafed and crumbled after cycling and was significantly less retentive in most statistical comparisons. CONCLUSIONS: All the silicone-based resilient liners retained the overdentures well. The plasticized acrylic was less retentive initially, and lost significant retention after 2740 cycles, compared with silicone-based resilient liners.

Acrylic Resins↗

Urinary retention following routine neurosurgical spine procedures.

BACKGROUND: The rate and duration of urinary retention after routine cervical and lumbar spine procedures were studied. METHODS: Preoperative, intraoperative, and postoperative factors related to urinary retention (age, sex, duration of operation, medications, Foley use, hospital stay, and cost) were analyzed in a retrospective review of 503 patients' charts. RESULTS: Urinary retention occurred 38% of the time following cervical and lumbar spine procedures. Advanced age and preoperative beta blockers contributed to a higher incidence of urinary retention. Preoperative anti-inflammatory medications and narcotic analgesics reduced the frequency of urinary retention. The duration of urinary retention was prolonged in older patients and patients who underwent intraoperative Foley catheterization. Urinary retention contributed to longer hospitalization and increased hospital costs. CONCLUSIONS: Transient urinary retention is a common complication of routine neurosurgical spine procedures that prolongs hospital stays and increases the costs of hospitalization.

Adult↗

Effect of a novel experience prior to training or testing on retention of an inhibitory avoidance response in mice: involvement of an opioid system.

These experiments examined the effects of a novel experience prior to training or retention testing on 24-h retention of an inhibitory avoidance response in mice. The experiments were based on previous evidence that novel training experiences release hypothalamic beta-endorphin. When given 1 h prior to training, the novel experience (clinging to the wire-mesh ceiling and exploring a small box) attenuated the memory-enhancing effects of post-training administration of naloxone as well as the enhancing effects of beta-endorphin administered prior to the retention test. The novel experience given prior to training did not block the enhancing effects of post-training administration of epinephrine. beta-Endorphin and the novel experience both enhanced retention performance when administered 1 h (as well as 3 but not 6 h) prior to the retention test. The enhancement found with both treatments was blocked by simultaneous administration of naloxone or by administration of propranolol a few minutes prior to the retention test. The findings of these experiments are consistent with the view that the effects of the novel experience are due to a release of endogenous beta-endorphin and provide additional evidence that the effects, on retention, of naloxone given post-training and beta-endorphin given prior to a retention test, are based on training-induced release of beta-endorphin.

Animals↗

Opposite effects on two different measures of retention following unilateral inactivation of the amygdala.

We previously reported finding differential effects of unilateral infusion of lidocaine into the right and left amygdalae prior to a retention test 24 h after one-trial inhibitory avoidance training. The present study was undertaken to determine whether the degree of training in an escape task influences the effects of unilateral inactivation of the amygdala with lidocaine prior to the retention test. Male Sprague-Dawley rats, implanted with bilateral cannulae aimed at the amygdaloid complex received 0 (no shock), 2, or 10 training trials in a footshock-motivated escape task (0.4 mA). Forty-eight h later, the rats received bilateral microinfusions into the amygdalae of either buffer, or lidocaine into one amygdala and buffer in the other, 5 min before they were tested for retention of the escape training using a continuous multiple trial inhibitory avoidance (CMIA) procedure (0.4 mA). Forty-eight h after CMIA training the animals were retested, this time without influence of drugs. As indicated by initial response latencies on the first retention test, unilateral inactivation of either the right or the left amygdala severely impaired retention performance for the escape training regardless of the number of prior escape training trials received. However, unilateral inactivation of either amygdala had no effect on acquisition of CMIA. Furthermore, unilateral inactivation of either amygdala during CMIA training did not affect retention tested 48 h later. These results suggest that the differential involvement of the right and left amygdalae may be limited to certain training conditions. Furthermore, these findings demonstrate opposite effects on 2 different measures of retention indicating that the method of testing retention affects the interpretation of the memory impairment induced by infusion of lidocaine into the amygdala.

Amygdala↗

Risk factors for acute urinary retention requiring temporary intermittent catheterization after prostate brachytherapy: a prospective study.

PURPOSE: We prospectively investigated prognostic factors for men undergoing transperineal radioactive seed implantation for prostate cancer at the University of Washington. METHODS AND MATERIALS: Between February and April, 1998, 62 consecutive unselected patients were prospectively followed after brachytherapy for early-stage prostate adenocarcinoma. Pretreatment variables included age, American Urological Association (AUA) score, uroflowimetry, and prostate volume by ultrasound. Nonrandomized variables included hormonal therapy, seed type, and use of pelvic radiotherapy. Patients were contacted by phone at one week postoperatively and at one-month intervals thereafter. Follow-up continued until all patients provided the date of last catheterization. RESULTS: Urinary retention rate at one week was 34% (21 of 63 patients). At one month, 29%; at three months, 18%; and at six months, 10%. Preoperative flow rate and post-void residual did not predict for retention (p =.48 and p =.58). Use of alpha blockers, hormonal therapy, type of seed (103Pd or 1251), or external beam radiotherapy had no impact on risk of retention at any followup point. Preimplant volume and AUA score predicted for retention on univariate analysis, but on multivariate analysis only postimplant volume remained significant (p =.02) for predicting retention risk and duration. CONCLUSION: Patients with large prostate size (>36 g) and higher AUA score (>10) appear to be at greater risk of risk of retention as well as duration of retention as defined in our study. Further investigation will be needed to clarify the risk of urinary retention for men undergoing brachytherapy.

Adenocarcinoma↗

Long-term retention of skilled visual search following severe traumatic brain injury.

We examined the long-term retention of a learned automatic cognitive process in 17 severe TBI participants and 10 controls. Participants had initially received extensive consistent-mapping (CM) training (i.e., 3600 trials) in a semantic category visual search task (Schmitter-Edgecombe & Beglinger, 2001). Following CM training, TBI and control groups demonstrated dramatic performance improvements and the development of an automatic attention response (AAR), indicating task-specific and stimulus-specific skill learning. After a 5- or 10-month retention interval, participants in this study performed a New CM task and the originally trained CM task to assess for retention of task-specific and stimulus-specific visual search skills, respectively. No significant group differences were found in the level of retention for either skill type, indicating that individuals with severe TBI were able to retain the learned skills over a long-term retention interval at a level comparable to controls. Exploratory analyses revealed that TBI participants who returned at the 5-month retention interval showed nearly complete skill retention, and greater skill retention than TBI participants who returned at the 10-month interval, suggesting that "booster" or retraining sessions may be needed when a skill is not continuously in use.

Adult↗

Retention impairment by posttraining epinephrine: role of state dependency and of endogenous opioid mechanisms.

Mice were trained in a step-through inhibitory avoidance task with a 0.6-mA, 60-Hz, 2-s footshock and were tested for retention 3 or 6 hr later. Posttraining intraperitoneal administration of a high dose (25.0 micrograms per mouse) of epinephrine (Epi) impaired retention; this effect was counteracted by another injection of the same dose of Epi given before retention testing either 3 or 6 hr after training. When administered before the 6-hr test but not the 3-hr test, however, Epi enhanced retention (i.e., above that of controls). The retention enhancement, but not the reversal of impairing effects of posttraining Epi, was antagonized by naltrexone (20.0 micrograms per mouse). Naltrexone, when administered alone, had no effect on retention when given before testing. However, posttraining administration of naltrexone produced an enhancement of retention detectable 6 but not 3 hr after training. Furthermore, posttraining naltrexone also blocked the impairing effect of posttraining Epi otherwise seen 6 hr after training. These results suggest that the impairment of retention caused by posttraining Epi is attributable to the induction of state dependency based on an Epi state. When the animals are tested 3 hr after training, this effect appears alone. But, when tested 6 hr after training, the Epi effect appears together with an opioid, presumably beta-endorphin-mediated, state dependency.

Animals↗

Isolation disrupts retention in preweanling rat pups.

Expression of an olfactory memory in 18-day-old rat pups was examined in eight experiments following brief manipulations of environmental conditions prior to a retention test. In the first experiment we found that retention was disrupted if a pup was placed in isolation for 3 hr prior to the retention test. The retention deficit persisted even when pups had 3-hr exposure to an anesthetized dam and siblings before testing. However, there was no deficit in retention if pups spent the pretest interval with a nonlactating foster dam, their father, or littermates. Finally, we found that this deficit in retention could be alleviated by cuing treatments that preceded the retention test following isolation. Both discrete cues used during training and returning the pup to the home cage with parents and siblings for 3 hr were found to alleviate the retention deficit caused by isolation. These data demonstrate that housing conditions can influence postacquisition memory processes in the young animal.

Animals↗

Five-year retention of the classically conditioned eyeblink response in young adult, middle-aged, and older humans.

Human participants who 5 years earlier participated in studies of acquisition of the classically conditioned eyeblink response to a tone conditioned stimulus (CS) and an air puff unconditioned stimulus (UCS) returned to the laboratory to test for retention of the conditioned response (CR). Retention consisted of 20 tone CS-alone presentations. Young adult participants (23-31 years of age at the time of retention testing) showed good retention of the CR (45%), middle-aged participants (45-52 years) showed reduced retention (28%), and older participants (69-78 years) showed little evidence of retention (< 5%). Retention testing was followed by reacquisition of the CR in which the CS and the UCS were again paired. The ability to reacquire the CR also showed a decline with age. The data suggest that the CR can be retained over long intervals and that the degree of retention is age dependent.

Adolescent↗

Some factors affecting retention forces with the use of denture fixatives in vivo.

Using the UCL retentiometer, the effect of three proprietary denture fixatives has been clinically investigated in 14 dentate subjects wearing mucosal-borne acrylic palatal plates over periods of 6 hours. The results showed that retention forces with saliva for the well-fitting plates were significantly better when compared with the forces for the ill-fitting plates. A substantial improvement in retention on all occasions was seen for both types of plate after the application of fixatives. An interesting observation of this study was that the use of paste and liquid fixatives rendered the ill-fitting plates as retentive as the well-fitting plates with the same fixatives. The test fixatives, however, showed significant differences regarding the onset and duration of action, depending on their physical formulation. The paste and liquid fixatives were found to have more delayed action than the powder fixative, but maintained the improved retention for a post-insertion period of more than 6 hours for both well-fitting and ill-fitting plates. Investigation of the effect on retention of different quantities of fixatives showed that larger amounts were associated with greater retention. The findings of these studies predict that a single application of 0.6 ml of either the paste or liquid fixatives used in this study is a recommended quantity which would provide and maintain the desirable retention for more than 6 hours in most cases of well-fitting complete dentures and those with retention problems. The powder fixatives though very effective immediately, would, however, require repeated applications every 3 hours or so, depending to some extent upon the use that the product will be put to.

Carboxymethylcellulose Sodium↗

Retention of maxillary implant overdenture bars of different designs.

STATEMENT OF PROBLEM: The specific degree of retention for overdenture attachments is unknown in relation to design, location, and alignment to supporting dental implants. PURPOSE: The purpose of this study was to evaluate the initial retention characteristics of 5 implant maxillary overdenture designs under in vitro dislodging forces. MATERIAL AND METHODS: A simulated edentulous maxilla was fabricated with 4 screw-type 3.75 x 13-mm implants anteriorly. Five overdenture designs with the following attachments were evaluated: 4 plastic Hader clips with an EDS bar; 2 plastic anterior Hader clips with an identical EDS bar; 2 Hader clips with 2 posterior ERA attachments; 3 Zaag attachments on a bar; and 4 Zaag attachments with no bar. Overdentures were fabricated with full palatal coverage. Each design was subjected to 10 consecutive retention pulls on a universal testing machine. Data were subjected to analysis of variance and t tests to determine differences. RESULTS: The highest average value after 10 pulls was 19.8 lb for the combination ERA and Hader clip design. The lowest retentive values were recorded for the 2 and 4 Hader clip designs (5.08 +/- 0.89 lb and 5.06 +/- 0.67 lb, respectively). Retention decreased over the course of consecutive pulls for all designs, especially for the most retentive designs. The smallest retention decrease occurred with the least retentive designs. CONCLUSION: The results of this in vitro study suggest that the precise selection and placement of attachments may affect the clinical success of maxillary implant-retained overdentures.

Dental Clasps↗

Evaluation of a cardiopulmonary resuscitation course for secondary schools retention study.

A retention study was implemented in Marshfield, Massachusetts in May 1974 in order to ascertain if cardiopulmonary resuscitation (CPR) skills could be retained by secondary school students who had 15 months previously received training in mouth to mouth resuscitation and cardiac compression. The retention study also addressed itself to the question whether a 28-minute "refresher" film on CPR skills prior to the test would serve to improve performance of CPR skills. (In the initial study, the students had been divided into two groups: those that received both didactic and practice sessions and those who received didactic training only.) All the initial practice group students (178 students who had received both didactic and practical CPR training) were divided equally into "film" and "no film" groups. A small sample of students (38) who had initially learned CPR skills from didactic materials only were also tested. These students were also divided into "film" and "no film" groups. Retention of continuous CPR skills, breaths anc compressions, showed very little loss. Retention of discrete CPR skills which included checking for breathing, opening the airway by tilting the head and lifting the neck, giving three quick breaths, feeling the pulse, and examining the pupil showed considerable loss of learning overtime. The film intervention did little to improve performance of CPR skills. No significant differences in performance were observed between "film" and "no film" groups. The findings of this study with respect to retention of continuous and discrete psychomotor sills closely parallel findings of the three-month retention study. In summary, this study would indicate that training of secondary students in CPR leads to good retention of essential skills. As indicated in the previous study, retention of the ancillary decision-making skills was not satisfactory. Methods for teaching these skills so that they will be retained over time need further development.

Educational Measurement↗

Management of postoperative urinary retention: a randomized trial of in-out versus overnight catheterization.

BACKGROUND: There has been no consensus on the best catheterization strategy for the management of postoperative urinary retention. A prospective randomized trial was undertaken to establish the best practice guidelines for the management of postoperative urinary retention. The authors also evaluated the contemporary incidence of urinary retention following different categories of general surgery and examined risk factors associated with its occurrence. METHODS: All patients who underwent elective inpatient surgery between January 2002 and June 2003 were recruited into the study. Patients who developed postoperative urinary retention were randomized to either having in-out catheterization or placement of an indwelling catheter for 24 h after surgery. RESULTS: A total of 1448 patients was recruited. The overall incidence of urinary retention was 4.1% (n = 60). Significant risk factors associated with postoperative urinary retention included old age, anorectal procedures and use of spinal anaesthesia. Comparison of re-catheterization and urinary tract infection rates between patients who were treated with in-out versus overnight catheterization found no significant differences. CONCLUSIONS: Postoperative urinary retention should be managed by in-out catheterization. Indwelling catheterization for 24 h appeared to bestow no additional benefits. The incidence of urinary retention increases with age, anorectal procedures and the use of spinal anaesthesia.

Adolescent↗

Effect of implant angulation upon retention of overdenture attachments.

INTRODUCTION: Overdentures supported and retained by endosteal implants depend upon mechanical components to provide retention. Ball attachments are frequently described because of simplicity and low cost, but retentive capacity of these components may be altered by a lack of implant parallelism. PURPOSE: The aim of this in vitro study was to investigate the retention of gold and titanium overdenture attachments when placed on ball abutments positioned off-axis. METHODS AND MATERIALS: Four ball abutments were hand-tightened onto ITI dental implants and placed in an aluminum fixture that allowed positioning of the implants at 0 degrees, 10 degrees, 20 degrees, and 30 degrees from a vertical reference axis. Gold and titanium matrices were then coupled to the ball abutments at various angles and then subjected to pull tests at a rate of 2 mm/second; the peak loads of release (maximum dislodging forces) were recorded and subjected to statistical analyses. A balanced and randomized factorial experimental design testing procedure was implemented. RESULTS: Statistically significant differences in retention of gold matrices were noted when ball abutments were positioned at 20 degrees and 30 degrees , but not at 0 degrees and 10 degrees. Statistically significant differences were noted among the titanium matrices employed for the testing procedure, as well as for the 4 ball abutments tested. Angle was not a factor affecting retention for titanium matrices. CONCLUSIONS: (1) The gold matrices employed for the testing procedures exhibited consistent values in retention compared to titanium matrices, which exhibited large variability in retention. (2) Angle had an effect upon the retention of gold matrices, but not for titanium matrices.

Analysis of Variance↗