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PubMed1975

Rapid diagnosis of sporotrichosis by immunofluorescent method.

Histopathological examinations fungal cultures and direct immunofluorescent staining of the pus and skin biopsy microsections with fluorescein isothiocyanate-labelled specific antiserum were performed for 13 patients suspected to be infected with Sporotrichum schenckii. While histopathological examinations could not give useful information, the latter two gave more reliable results which could support the clinical diagnosis. The direct immunofluorescent staining test could be used as a method for rapid diagnosis of sporotrichosis.

Antigens, Fungal↗
PubMed1994

Sporotrichosis in north-west India.

Twelve culture proven patients of sporotrichosis were seen over a period of 4 1/2 yr in the north-western region of this country. Most of the patients (75%) were from Himachal Pradesh, with slight female preponderance. The right upper limb was commonly (58.3%) involved; gardeners and housewives being the common sufferers. Localised lymphocutaneous variety was the commonest presentation (91.7%), except in one patient, where after initial involvement of the face, the lesion extended to the right upper limb and trunk. All but one patient responded to oral potassium iodide therapy; this patient with mixed infection of Sporothrix schenckii and Cladosporium species, required in addition, amphotericin B therapy.

Amphotericin B↗
PubMed1993

Sporotrichosis of abdominal wall.

A rare case of sporotrichosis of abdominal wall has been described from high mountainous region of Himachal Pradesh. Its clinical importance has been discussed in the light of available literature.

Abdominal Muscles↗
PubMed1993

Therapy of sporotrichosis.

Sporotrichosis is a fungal infection caused by the dimorphic organism, Sporothrix schenkii. This etiologic agent typically gains entrance into the skin by traumatic implantation of infected soil or plant materials. The majority of cases are of the fixed cutaneous or lymphangitic cutaneous varieties, and less commonly, hematogenous dissemination to skin or viscera occurs. Untreated, the disease may spontaneously resolve or persist and gradually progress over time, its virulence being less than that of other dimorphic fungi. Potassium iodide remains a favored treatment for uncomplicated cutaneous disease. Amphotericin B, with its high toxicity, has historically been reserved for recalcitrant cutaneous or disseminated disease. Itraconazole, the newest triazole antifungal to become available in the United States, seems to be highly effective against Sporothrix schenkii without significant adverse effects and will likely become the first line therapy for all forms of this disease in the future.

AIDS-Related Opportunistic Infections↗
PubMed1993

[Experience with 241 sporotrichosis cases in Chiba/Japan].

Between 1965 and 1991, 241 cases of sporotrichosis have been seen in the Department of Dermatology at Chiba University Hospital. Children under the age of 12 and patients older than 40 years had a higher rate of infection. Most affected were the upper extremities, followed by lesions of the face. One hundred twenty-four patients (51.5%) were farmers. The decrease in the number of patients observed since 1983 is attributed mainly to a drop in the percentage of the local population involved in agriculture. There was no correlation between the number of infections and the amount of precipitation, as had been suggested earlier. The patients were treated with potassium iodide and in some cases with additional thermotherapy.

Adolescent↗
PubMedDate not supplied

Response of sporotrichosis granuloma to local application of iodine.

Chronic sporotrichosis granuloma of the skin is usually the result of non compliance with oral iodine therapy for whatever reason. Excision of the lesion, local iodine application with povidone iodide for six days and delayed primary skin grafting is presented as a quick, effective and acceptable alternative, if oral treatment is not tolerated. The ineffectiveness of local excision and grafting without adequate iodine therapy is demonstrated by this case.

Administration, Oral↗
PubMed1997

[A case of sporotrichosis with numerous fungal elements].

We report a case of cutaneous sporotrichosis with numerous fungal elements in a 59-year-old Japanese male treated with topical corticosteroid ointment. Histologically, granulomas were found with a few of neutrophils, many lymphocytes and plasmocytes in the upper dermis. Numerous yeasts were found in the granulomas. They were stained with periodic acid Schiff, but not with hematoxylin and eosin. No asteroid body was detected. After treatment of the corticosteroid, histological pattern is different from usual pattern, such as the number of fungal elements is larger, extent of neutrophil infiltration is slighter and very rare appearance of asteroid body. These histological differences are likely to be induced by the local immunosuppression after corticosteroid treatment.

Adrenal Cortex Hormones↗
PubMed1998

Itraconazole therapy in lymphocutaneous sporotrichosis: a case report and review of the literature.

A 24-year-old white man had a six-month history of nontender nodules on the dorsal aspect of the right hand. The lesions were diagnosed as lymphocutaneous sporotrichosis based on clinical appearance, histopathologic examinations, and fungal culture. Therapy with itraconazole was started. Considerable improvement was recorded after two months, when all of the lesions diminished in size and were no longer nodular in appearance.

Adult↗
PubMed1998

Cutaneous sporotrichosis presenting as a keratoacanthoma.

Sporothrix schenckii is a ubiquitous dimorphic fungus with a variety of clinical presentations, including imitation of other diseases such as pyoderma, rosacea, and pyoderma gangrenosum. A case in which sporotrichosis appeared as a keratoacanthoma-like nodule on the lower lip of a young woman is presented, with treatment considerations and diagnostic pitfalls.

Adult↗
PubMedDate not supplied

[Subcutaneous mycotic cysts in Madagascar (Histological aspects. Diagnostic value of the Gomori-Grocott stain. Associations with pheo-sporotrichosis)].

The authors report three cases of mycosic subcutaneous cysts and study the problem of the phaeo-sporotrichosis, a cystic lesion due to dematies brown fungi which are often introduced under the skin by a sting. Because of the absence of brown pigmentation of the fungi present in the three cases reported, the authors propose to group these various cysts under the name of "syndrome of the mycosic cysts" a part of which only being constituted by the phaeosporo trichosis. They emphasize the importance to draw surgeons' attention on such lesions, a priori clinically banal, and pathologists' attention on Gomori-Grocott staining in tropical countries.

Adult↗