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A comparison of the activity of the sympathoadrenal and adrenocortical system under inhalation anesthesia techniques.

Epinephrine, norepinephrine, ACTH and cortisol plasma levels as well as heart rate and blood pressure were studied in 32 patients undergoing ophthalmic surgery. Epinephrine levels rose significantly during nitrous oxide anesthesia and also during enflurane-nitrous oxide anesthesia, whereas they fell slightly during halothane-nitrous oxide anesthesia. Norepinephrine levels remained unchanged. ACTH and cortisol levels increased during all three types of anesthesia. During nitrous oxide and enflurane-nitrous oxide anesthesia, heart rate and blood pressure were elevated, halothane nitrous oxide anesthesia was associated with an increased heart rate but not with increased blood pressure.

Adolescent↗

[Effect of nitrous oxide inhalation anesthesia on sero-mucous secretions of the tympanum].

It is known that nitrous oxide anaesthesia results in an increase of the middle ear pressure. The aim of this project was to find out, if an increase of the middle ear pressure due to high concentration of nitrous oxide could lead to evacuation of the seromucoid secretion through the Eustachian tube. In 37 children (64 ears) scheduled for myringotomy, tympanograms were performed immediately before and during anaesthesia, the middle ear fluid was confirmed by myringotomy and, if any, sucked out. Both the comparison of the tympanograms prior and during the anaesthesia and the results of myringotomy led to a conclusion, that, in general, nitrous oxide anaesthesia induces no evacuation of middle ear fluid via the Eustachian tube.

Acoustic Impedance Tests↗

[Brain structural monoamines under inhalation anesthesia].

It was established in albino rats that the activity of the processes that are responsible for the functioning of the metabolic link in noradrenaline synthesis varies under ether and ftorotan anesthesia. It was recorded that there is an increase in the activity of DOPA decarboxylation in the brain under deep ether anesthesia as well as in the activity of dopamine decarboxylation during egress from anesthesia. Ftorotan anesthesia is characterized by increased hydroxylation of phenylalanine and decarboxylation of DOPA, and by inhibition of the activity of tyrosine and dopamine hydroxylation. Egress of animals from ftorotan anesthesia is associated with an intensive noradrenaline formation in the brain.

Anesthesia, Inhalation↗