[Pathomorphological changes in amniotic fluid embolism. (Experimental study)].
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We report an uncommon case of amniotic fluid embolism (AFE) in a 24-year-old woman with a 26th-week, second pregnancy. Clinical manifestations were dominated by acute respiratory distress and pulmonary edema. Recovery was complete. Early invasive hemodynamic studies showed normal function of the left ventricle with a low pulmonary artery occluded pressure. These findings are controversial to the concept of cardiogenic pulmonary edema in AFE.
Amniotic fluid embolism (AFE) is a dramatic, rare and frequently lethal complication of pregnancy. Perusal of the National Health and Medical Research Council reports on Maternal Deaths in the Commonwealth of Australia for the years 1964-1984 (1-7) shows that there have been 1,193 maternal deaths in this 21-year period, of which 54 (4.5%) were due to AFE. This paper presents data regarding these deaths and also describes 2 cases of AFE which occurred at Caesarean section performed for placenta praevia, one of which was lethal.
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