[Use of intrauterine fetal transfusion in treatment of grave cases of erythroblastosis (first results)].
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In 79 pregnancies with erythroblastosis fetalis, fetal blood was sampled to assess the level of anaemia. Significant correlations were found between the haemoglobin concentration and umbilical artery pH, bicarbonate concentration and base excess. Compensatory mechanisms help to maintain oxygen supply in anaemia but their failure is associated with hydrops fetalis.
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Four pregnancies managed with erythrocyte membrane oral therapy because of severe Rh disease are presented. Reduction in anti-(D) production was the goal of the study. A patient was classified as having severe Rh immunization if there was a history of fetal loss due to erythroblastosis fetalis prior to 26 weeks.
In a referral perinatal center a detailed study was made of all the perinatal deaths that occurred during 1 year; they were analyzed according to primary diagnoses on the basis of a classification by R. L. Naeye which included the placenta. This method points to the areas in which special efforts at prevention should be made, and it should become a reliable basis for comparison.
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