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False positive malignant peritoneal cytology and psammoma bodies in benign gynecologic disease.

OBJECTIVE: To determine the incidence of false positive malignant peritoneal cytology and psammoma bodies associated with benign gynecologic disorders. STUDY DESIGN: Pelvic peritoneal fluid was prospectively collected for cytologic examination from 119 women undergoing laparoscopy for benign conditions (infertility, 67; pelvic pain, 35; elective sterilization, 17). The median age was 30. No patient had laparoscopic gross cancer or histologic evidence of cancer. RESULTS: The peritoneal cytology of 2 of 119 cases (2%) contained cells with features suggestive of malignancy, and 6 of 119 cases (5%) contained psammoma bodies. Both cases of false positive peritoneal cytology and four of six with psammoma bodies were associated with endometriosis. All cases were followed for a minimum of two years, and no patient had developed cancer. CONCLUSION: Peritoneal fluid from cases of benign gynecologic disorders, especially endometriosis, can contain psammoma bodies and cells suggestive of malignancy.

Adult↗

[Metabolic changes in patients operated on in gynecologic diseases under ketamine anesthesia].

Changes in biochemical parameters have been studied in 58 patients during short-term gynecological surgery performed under ketamine or ketamine-diazepam anesthesia. Surgery under ketamine monoanesthesia was accompanied by a considerable activation of sympathoadrenal and hypophyseal-adrenal systems, which was regarded as inadequate anesthesia. A significant decrease in plasma histamine level has been observed.

Adrenal Glands↗

Gynecologic disease in young, sexually active women.

There has been a significant change in adolescent sexual behavior in the past decade. This report of 1,594 young, sexually active women, primarily from middle and upper socioeconomic backgrounds, identifies the obstetric and gynecologic problems characteristic of the group. While supposedly in a low-risk category these patients displayed a high incidence of cervical epithelial abnormality, problem pregnancy, and other obstetric and gynecologic abnormality. The incidence of veneral disease was somewhat lower than anticipated.

Adolescent↗

[A comparison of Clearview Chlamydia diagnostic tests and direct immunofluorescence (Chlamyset Antigen) in inflammatory gynecological diseases due to Chlamydia trachomatis].

The diagnostic performance of two direct antigen tests is compared, using parallel samples from 90 gynecologic patients. The latter were selected because of clinically suspicious symptoms for chlamydial infection. The incidence of infection in the study group was 33.3%. Compared to direct immunofluorescence Clearview Chlamydia had sensitivity of 80%, specificity of 100%, and the agreement between the two methods was 93.3%. Clearview Chlamydia may serve as a useful diagnostic test in case there is no available laboratory equipment and trained personal.

Adolescent↗