[Biochemical changes in heart arrest].
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Cultured myocardial cells of new-born rats which were arrested by 17.6-37.6 mM KCl regained their ability to contract spontaneously after perfusion with 8-10(-4)-4-10(-3) M dibutyryl cyclic AMP. This adrenaline-like action of DbcAMP is compatible with the notion that cyclic AMP is involved as a second messenger in the action of cyclic AMP-raising adrenergic agents on cardiac activity.
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A case of intraoperative death because of right heart failure due to extensive pulmonary fat and bone marrow embolism in an 85 year old woman during cemented total hip replacement under spinal analgesia is reported.
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