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Breast tomography with synchrotron radiation: preliminary results.

A system for in vivo breast imaging with monochromatic x-rays has been designed and built at the synchrotron radiation facility Elettra in Trieste (Italy) and will be operational in 2004. The system design involves the possibility of performing both planar mammography and breast tomography. In the present work, the first results obtained with a test set-up for breast tomography are shown and discussed. Tomographic images of in vitro breasts were acquired using monochromatic x-ray beams in the energy range 20-28 keV and a linear array silicon pixel detector. Tomograms were reconstructed using standard filtered backprojection algorithms; the effect of different filters was evaluated. The attenuation coefficients of fibroglandular and adipose tissue were measured, and a quantitative comparison of images acquired at different energies was performed by calculating the differential signal-to-noise ratio of fibroglandular details in adipose tissue. All images required a dose comparable to the dose delivered in clinical, conventional mammography and showed a high resolution of the breast structures without the overlapping effects that limit the visibility of the structures in 2D mammography. A quantitative evaluation of the images proves that the image quality at a given dose increases in the considered energy range and for the considered breast sizes.

Adipose Tissue↗

Nevus anelasticus, papular elastorrhexis, and eruptive collagenoma: clinically similar entities with focal absence of elastic fibers in childhood.

Focal absence of elastic fibers is a defining characteristic of three rare, clinically similar conditions: nevus anelasticus, papular elastorrhexis, and eruptive collagenoma. We present a 16-year-old with nevus anelasticus treated with intralesional steroid injections, resulting in erythematous atrophic depressions. We also review the English language literature on nevus anelasticus, papular elastorrhexis, and eruptive collagenoma. There may be sufficient clinical and histopathologic similarity to indicate that these three entities represent a single disease or disease spectrum. We believe that this entity should be referred to as papular elastorrhexis.

Adolescent↗

A review of parameters for the bioelectrical characterization of breast tissue.

In the data set collected by the authors in freshly excised breast tissue, the admittance loci generally differed from circular arcs, rendering the calculation of the usual set of parameters impossible. Alternative parameters were used for the analysis of these data. The present study consists of the definition and evaluation of a set of such parameters aimed at the characterization and differentiation of breast tissues. These parameters were defined so that their calculation does not require the fit of circular arcs to the experimental points and is independent of any equivalent circuit model. The results of the statistical analysis showed significant differences between most of the tissue groups, especially between cancerous tissue and all the other groups, which confirmed that impedance spectroscopy can be considered as potentially suitable for breast cancer detection.

Adipose Tissue↗

The fibromatoses.

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Age Factors↗