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[Occupational dermatitis in the agriculture-food industry environment].

The agricultural and food professions are those that touch agriculture, but also the restoration, the kitchens, and the employees of slaughterhouses. Various occupational skin diseases touch these salaried employees or craftsmen: eczemas or contact hives with plants or meats and fleshes of animals and all chemical substances that are added: pesticides, food additives and various preservatives. Irritation contact dermatitis or real skin burns are observed with housekeeping products imposed by the sanitary norms, increasingly powerful, but as increasingly caustic. Infectious illnesses transmitted from the animal to the man are sometimes observed especially among the breeders and employees of slaughterhouses.

Agriculture↗

[Prevalence of changes in performance, subjective symptoms and occupational dermatitis before and after carrying out improvements in the surgical block of the Modena Polyclinic].

The Preventive Medicine Unit for Personnel in the USL N. 16 of Modena has conducted a study to evaluate the prevalence of subjective symptoms and professional dermatitis among nurses working in a general surgery operating theatre of the Modena "Policlinico" Hospital (36 and 41 employees were studied respectively in 1990 and 1991), before and after the installation of gas evacuators and a modification in the use of detergent and disinfectant substances. The study demonstrates that installation of gas evacuating systems, if not supported by an intervention of air-conditioning plant, does not sufficiently reduce alterations in subjective symptoms. On the other hand, the modifications in the use of detergent and disinfectants has demonstrated a favourable reduction in the prevalence of professional dermatitis (from 43% to 18%; chi2 = 4.35, p = 0.037).

Air Pollutants, Occupational↗

[Occupational dermatitis in construction and public workers].

Construction workers perform a large variety of duties concerned with building, repairing, and wrecking buildings, bridges, dams, roads, railways and so on. The work may include mixing, pouring and spreading concrete, asphalt, gravel and other materials. Despite the increasing mechanization of construction and the more frequent use of precast concrete sections, contact with wet cement still occurs, particularly in small jobs. The work is hard physical labor, often under difficult conditions, including hot, cold, and wet weather. Occupational diseases of the skin in the construction have paralleled industrial development.

Construction Materials↗

Occupational dermatitis from a one-component naphthalene type epoxy adhesive.

In an electronics plant, a new one-component naphthalene type epoxy resin was used as an adhesive for reinforcing a circuit board. The resinous part of the adhesive consisted of diglycidyl ether of bisphenol A (DGEBA) and 1,6-bis(2,3-epoxypropoxy)naphthalene type epoxy resins. The hardener was methylhexahydrophthalic anhydride (MHHPA). Of 54 workers, 15 (27.8%) were diagnosed to have work-related dermatitis but were not patch tested. Therefore, it was impossible to determine the specific agent responsible for the worker's symptoms or to distinguish between allergic and irritant contact dermatitis. They worked without protective gloves until they started to develop skin symptoms. The hands were the commonly affected region (13 out of 15 cases). The latent period of dermatitis was very short (mean 2.2 weeks). Of these, 10 cases (66.7%) received medication for dermatitis, and 9 cases (60%) were transferred to other work. The work-related skin symptoms were closely related to the specific tasks, i.e., filling dispensers with the adhesive and manual application of the adhesive to a portion of a circuit board using a dispenser. For occupational hygiene reasons, contact with epoxy resins should be minimized by taking all possible measures into use, including protective gloves. Further studies are required to clarify the allergenicity of 1,6-bis(2,3-epoxypropoxy)naphthalene, since very little is known about the mechanism through which it leads to the symptoms of dermatitis.

Adhesives↗

Primula allergic dermatitis simulating occupational contact dermatitis induced by metals, oils and greases.

A case of the hands and face dermatitis in a patient employed in a store with motor-car spare parts is presented. Both the patient and her doctor were convinced that skin lesions were caused by the contact with metals, oils and greases. After detecting allergy to primine (after 48 and 96 h, + +), the patient recalled that two months earlier she had started to grow primrose (Primula obconica) at home. Patch tests with the primrose leaf and flower were also positive (+ +). The presented case provides evidence that routine primine testing is essential in all patients with suspected contact allergy dermatitis. In Poland like in the majority of countries, primina is not included in the standard kit.

Dermatitis, Occupational↗

Occupational dermatitis from soldering flux.

The aim of this study was to determine the specific agent responsible for eczema on the forearms of 2 electronic assemblers who cleaned out a flux-spraying unit once a week. Soldering flux can be a source of skin irritation as well as allergy. Patch test with dried flux residue (as is) and rosin in dilution series of 20%, 10%, and 1% in olive oil was performed. Readings were taken on day 2 and day 3. The rosin in dilution series was negative; however, the flux residue gave a + reaction on day 2, and by day 3 the reaction had weakened (+?). Similar results were obtained in 2 unexposed controls. Patch tests results in our cases indicate that the flux used in the soldering process caused irritant contact dermatitis.

Adult↗

Occupational issues of allergic contact dermatitis.

Occupational contact dermatitis is often of multifactorial origin, and it is difficult to determine the relative significance of the various contributing factors. Contact allergies are relevant in 20-50% of recognised occupational contact dermatitis cases. The reported frequency in different studies varies, depending on differences in how occupational diseases are notified and recognised, in types of occupation in a geographical area, and the "quality" of the dermatological examination, including the accuracy of the diagnostic patch-test investigation. However, the clinical relevance of the reported contact allergies is often uncertain. Many occupational contact dermatitis patients with documented contact allergies develop chronic eczema, in spite of work changes and attempted allergen avoidance. Recognition/non-recognition of a notified case may be based on circumstantial evidence, because of difficulties in the establishing of a firm proof of work exposure and subsequent development of skin disease. Reliable quantitative exposure measuring techniques are needed. Methods are developed for the measurement of exposure to allergens such as nickel and acrylates, which makes it possible for exposure-effect relationships to be established with increased certainty. For prevention of allergic contact dermatitis it was a major step forward, with mandatory ingredient labelling of cosmetic products. However, improved labelling of the presence of contact allergens in household and industrial products is needed. For the identification of hazardous contact allergenic compounds, guinea pig or mice assays are still required. The local lymph node assay (LLNA), which is an objective and sensitive mouse assay has now been internationally validated and accepted.

Dermatitis, Allergic Contact↗

An ultrastructural study of chronic chromate hand dermatitis.

Occupational chromate dermatitis is one of the most common occupational diseases, predominantly causing hand eruptions. The ultrastructural manifestations of this condition have not been previously described. In this study, 7 cases of chronic occupational chromate hand dermatitis were investigated. Biopsies were taken from palmar skin and examined using light and electron microscopy. The ultrastructural features of chronic chromate dermatitis are similar to those of acute inflammatory dermatoses, even in the absence of clinical or histological features of an acute inflammatory process. Most changes are probably mechanical in nature and are a result of increasing intercellular oedema. Several features of chronic chromate dermatitis are common to other inflammatory dermatoses, including the presence of marked intercellular oedema of the lower epidermal keratinocytes, the formation of intracellular vacuoles in cells of the lower epidermis and the presence of milder ultrastructural changes in the midepidermis. The study has documented the presence of dendritic, spindle-shaped granular cells in the upper dermis, which have not previously been described in chromate dermatitis. The epidermis in chromate dermatitis appears to have fewer desmosomes when compared with other forms of dermatitis.

Adult↗

Occupational issues of irritant contact dermatitis.

Occupational irritant contact dermatitis (ICD), a non-immunological cutaneous inflammatory response to a workplace substance, comprises a major portion of occupational dermatoses in industrialized societies, resulting in considerable social and economic implications. The sheer morphological variety of ICD presents a diagnostic and classification challenge; ideotypes identified to date include acute, chronic and cumulative irritant dermatitis, delayed acute irritant dermatitis, irritant reaction, pustular irritant dermatitis, suberythematous irritation, sensory irritation, friction dermatitis and airborne dermatitis. Hand dermatitis is the most frequent manifestation of occupational ICD. This article reviews the various types of ICD, the epidemiological data available to date, risk factors, pathophysiology, diagnosis and management of ICD, emphasizing occupational issues.

Dermatitis, Irritant↗

Milk recorder dermatitis.

Occupational contact dermatitis to Bronopol and Kathon CG has been identified in 3 milk recorders following the introduction of a new milk preservative. The source of exposure, sensitising potential and measures for prevention are discussed.

Adult↗

Intervention implementation research: an exploratory study of reduction strategies for occupational contact dermatitis in the printing industry.

BACKGROUND: Occupational dermatitis is a problem in the printing industry but can be avoided through adequate protective measures. Research into intervention implementation is fundamental to the success of a formal intervention effectiveness trial. OBJECTIVES: The preliminary testing of four risk reduction strategies for occupationally caused dermatitis, which represent a range of approaches and cost implications. PATIENTS/METHODS: The strategies, the provision of (i) skin checks plus treatment advice; provision of (ii) gloves of the correct type/size plus use of an after-work cream; provision of (iii) information highlighting the problem of occupational dermatitis and (iv) development of a best practice skin care policy, were evaluated over 3 months in two non-randomly selected companies. A post-intervention evaluation into the effectiveness and efficacy of the intervention was also carried out. RESULTS AND CONCLUSIONS: All interventions were found to be acceptable to some extent. No single intervention appeared to be completely effective. The most practical intervention appeared to be the regular use of gloves of the correct type and size. This preliminary intervention study has demonstrated an improvement in the skin condition of workers examined and points towards the need for further testing of risk reduction strategies for the prevention of dermatitis in the printing industry on a much larger scale.

Dermatitis, Occupational↗

What is occupational contact dermatitis? An operational definition.

Occupational contact dermatitis remains an important cause of disability. Eight steps in an operational definition of OCD are as follows: 1. Relevant clinical history 2. Relevant morphology 3. Positive diagnostic patch test with appropriate vehicle and concentration 4. Repeat patch test when excited skin syndrome is suspected 5. Positive provocative use test or repeat open application test to refine clinical relevance 6. Serial dilutions, when necessary, of the chemical tested 7. Reviewing controls for nonirritating concentrations when this is not known by the investigator 8. Generally, clearing of the dermatitis when allergen is removed, or exposure significantly decreased The diagnosis is not always easy. Well-conducted clinical investigations are needed, including clinical history, clinical examination, and patch testing with careful follow-up. However, many of the chemicals reported in the literature as sensitizers induce only sporadic allergic reactions. Thus, epidemiologic animal and human studies are necessary to determine the capacity of the chemicals used in industry to induce contact dermatoses. It is necessary to standardize the predictive tests to compare results among laboratories and to predict the potential for sensitization.

Animals↗