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At least 307 records · Page 17Linked to original sources

Traumatic retinal detachment.

Seventy-seven patients developed retinal breaks following an episode of ocular contusion, and 65 (84.4%) of these developed rhegmatogenous retinal detachment. Surgical treatment successfully restored or maintained retinal apposition in 74 (96.1%) of the eyes. Thirty-six (46.8%) eyes recovered visual acuity of 6/9 or better. Of the retinal breaks recognised dialysis at the ora serrata was observed in 49 eyes, of which 28 were situated at the lower temporal quadrant. Seventeen eyes had irregular breaks arising within necrotic retina at the site of scleral impact. Twenty-four (31.2%) patients had retinal break or retinal detachment diagnosed within 24 hours of injury and 49 (63.6%) within six weeks. Immediate retinal detachment was a feature of necrotic retinal breaks, while inferior oral dialyses led to a slow accumulation of subretinal fluid. Delayed diagnosis of retinal detachment was due either to opaque media or to failure to examine the retina after injury. Visual prognosis was good when retinal break or detachment were diagnosed within six weeks of injury. However, those patients who escaped initial retinal examination and were lost to follow-up had a less favourable visual outcome.

Adolescent↗

[Myopia and rhegmatogenous retinal detachment].

There is a statistically significant correlation between rhegmatogenous retinal detachment and myopia. The prevalence of retinal detachment in myopic eyes is related to the prevalence of the disease precursors in such eyes. In most cases retinal detachments in myopic eyes share the clinical features of retinal detachments in emmetropic eyes. However, retinal detachments associated with giant tears and retinal detachment with atrophic holes in lattice, which are infrequent, show an increased prevalence in the myopic eye. In addition, retinal detachments associated with post-equatorial paravascular retinal tears, as well as retinal detachments with macular holes are specific or the myopic eye. Surgery is required in the management of retinal detachment. At present permanent retinal reattachment can be achieved in approximately 90% of eyes. The indications for prophylactic treatment remain debated. The high incidence of failures of prophylactic treatment is probably related to the limits of the current techniques.

Aging↗

Characteristics of rhegmatogenous retinal detachment.

Characteristics of rhegmatogenous retinal detachment and its predisposing factors were studied in a consecutive series of 342 patients operated on for retinal detachment (RD) at the University Eye Hospital in Helsinki in 1978-1981. On these, 234 were pre-operatively examined and operated on by the senior author. The mean age of the patients was 52.8 +/- 1.0 (range 5.7 to 83.0) years, 49.1% were males, 50.9% females. Bilateral RD occurred in 9.9%, and another 4.7% had been treated for retinal breaks in the fellow eye. Of the main predisposing factors, myopia (greater than or equal to -1.0 D) was found in 50.6% of the phakic eyes, 23.0% of the eyes were aphakic, and lattice degeneration was found in 15.1% and trauma in 11.9% of the whole series. In the nontraumatic phakic group, lattice degeneration was present in 31.3%. In the aphakic group, 25.9% had underlying myopia and 8.1% showed lattice degeneration. The relative importance of these factors varied with age. Total RD was found in 60 eyes (17.0%), most commonly in aphakic eyes (32.1%). Macula was detached in 56.5%. Two or more retinal breaks were found in 40.9%. The type of breaks varied with age and refraction. Oral dialysis was common before the age of 20 in non-myopic phakic eyes. Between 20 and 39 years, tears and holes were equally common, and after 40 years of age tears predominated. Tears outnumbered holes both in nonmyopic and myopic eyes, most round holes were found in myopic eyes. In 11.6% of the eyes no sure retinal breaks were detected. Relation of retinal breaks to peripheral retinal degenerations was studied.

Adolescent↗

Experimental retinal detachment in the rabbit. Penetrating ocular injury with retinal laceration.

Retinal detachment was studied in a rabbit model of penetrating ocular injury with retinal laceration. The injury was an 8 mm perforation through the sclera, choroid, and retina with vitreous loss and incarceration. When the injury was located at the equator of the globe, the rate of retinal detachment was 16%, but if located at the ora serrata, the rate was 78%. The higher rate of retinal detachment following injuries located at the ora serrata is probably due to the involvement of the vitreous base.

Animals↗

Glaucoma following retinal detachment operations.

After retinal detachment operations 1-5% of the patients develop glaucoma. If this occurs directly after the operation it is the result of mechanical narrowing of the chamber angle. This can be the result of indentation due to an exoplant or encircling band causing forward displacement of the lens/iris diaphragm. Other causes are torsion of the ciliary body or a ciliary block due to serous detachment of the choroid caused by venous compression or diathermy. Ischaemia of the anterior segment sometimes leads to glaucoma in the long run; this is then the result of rubeosis iridis. Conducive factors are detachment of the recti muscles, arterial and venous compression by the exoplant or encircling band and the use of diathermy. When performing such operations it is advisable to take these risks into account and to keep a check on the intraocular pressure after the operation. A patient is described who, as the result of ischaemia, eventually developed ribeosis iridis with neovascular glaucoma, leading to loss of the eye.

Aged↗

Scleral buckle revision to treat recurrent rhegmatogenous retinal detachment.

Recurrent rhegmatogenous retinal detachment sometimes occurs following scleral buckling surgery in the absence of advanced proliferative vitreoretinopathy (grade C-2 or greater). Such detachments can occur because: 1) the scleral buckle is not properly positioned beneath the original break; 2) the buckle is not high enough; 3) the break is elevated off the buckle due to progressive vitreous traction; 4) there are new breaks; and 5) chorioretinal adhesion is insufficient. Techniques that may be useful for reattaching the retina in these cases include: 1) adding scleral buckling material to augment the original buckle; 2) modifying the existing buckle without adding new material; 3) replacing the original buckle with other material; 4) re-treating inadequately closed breaks; and 5) combinations of these four techniques. Vitrectomy may be avoided in many cases.

Adolescent↗

[Primary vitrectomy in rhegmatogenous retinal detachment].

For therapy of uncomplicated rhegmatogenous retinal detachment, a buckling procedure is the standard surgical technique today. In complicated cases, e.g., retinal redetachment after a failed buckling procedure, vitrectomy is established. Meanwhile it is being discussed whether or not certain retinal detachments, e.g., with atypically large tears, should be treated with primary vitrectomy. We studied retrospectively all primary vitrectomies for retinal detachment without proliferative vitreoretinopathy (PVR) that were operated upon during 1992 in Würzburg Eye Hospital (32 patients). In 56% (18 eyes) of the patients a subtotal or total retinal detachment was seen preoperatively; in 47% (15 eyes) the macular region was detached. In 25% (8 eyes) large retinal tears were seen (> 1 h). The other patients showed atypical horseshoe tears partly central to the equator or multiple holes. Seventy-eight percent (25 eyes) of all cases were successfully vitrectomized with one operation and revealed good results using intraocular tamponade (SF-6/air mixture). Seven patients needed further vitrectomy partly using silicone oil as an intraocular tamponade. In cases of rhegmatogenous retinal detachment with atypical tears or non-identified holes, vitrectomy without the buckling procedure is a good alternative, because the rate of successful results is as high as what is achieved with buckling procedure in uncomplicated cases.

Adult↗

The effect of chemoreduction on retinoblastoma-induced retinal detachment.

BACKGROUND: Retinoblastoma with total retinal detachment traditionally has been managed with enucleation. We employed a chemoreduction protocol in an effort to reduce the tumor size to allow for focal treatment and salvage of the eye. METHODS: A prospective study was performed to assess the effects of a 2-month chemoreduction regimen of vincristine, etoposide, and carboplatin on massive retinoblastoma with total retinal detachment. RESULTS: We treated 17 eyes with total retinal detachment from retinoblastoma in 13 patients over a 14-month period. At the initial examination, the mean tumor base was 15 mm and mean thickness was 10 mm. The eyes were classified as Reese-Ellsworth group V in 16 cases (94%) and group III in one case (6%). The retina was totally detached with serous subretinal fluid in all cases. After 2 months of chemoreduction, all tumors showed a response, and the tumors decreased to a mean base of 10 mm and thickness of 5 mm. Overall, a mean of 33% decrease in base and 47% decrease in thickness was noted. The subretinal fluid had resolved completely in seven eyes (41%), leaving flat retina. In three eyes (18%), partial resolution was achieved; in seven eyes (41%), minimal resolution of the subretinal fluid at the 2-month period was noted. By last follow up, at a mean of 10 months after initiation of chemoreduction, complete resolution of the subretinal fluid occurred in 13 eyes (76%) and partial resolution of subretinal fluid occurred in four eyes (24%). CONCLUSION: Preliminary observations suggest that chemoreduction may be an important tool in the initial management of retinoblastoma, even for large tumors with total retinal detachment. Tumor shrinkage may be dramatic and subretinal fluid resolution may be complete.

Antineoplastic Combined Chemotherapy Protocols↗

[Histological changes related to scleral buckling for treatment of retinal detachment].

Treatment of retinal detachment frequently uses biocompatible materials to obtain scleral buckling. These materials are not devoid of consequences on surrounding tissues. In 3 eyes enucleated for failure of surgical treatment using scleral buckling materials, the changes prompted by episcleral implants could be observed. The sclera underwent both an inversion of its curvature and a reduction of its thickness under the material, as well as an encapsulation of the material was observed. While a silicone sponge was used in part to encircle one of these eyes, its capsular inner surface was regular and smooth. In contrast, hydrogel implants used in the three eyes showed a peripheral fragmentation prompting in two of them a typical foreign body giant cell granulomatous reaction. Changes in scleral curvature and scleral thinning were observed reflecting the consequences of the buckling procedure. The capsule formation occurred as it does for any nonabsorbable matérial implanted in tissues. Degradation and fragmentation of the hydrogel material suscitated a granuloma in response to fragments. These hydrogel specific changes should be recognized on microscopic examination of slides of either capsule or eyes previously in contact with this implanted material. They attested of the instability of hydrogel after implantation.

Aged↗

Perfluorocarbon liquid-assisted external drainage in the management of central serous chorioretinopathy with bullous serous retinal detachment.

The differential diagnosis of serous retinal detachment (RD) includes Vogt-Koyanagi-Harada syndrome, severe hypertensive choroidopathy, posterior scleritis, multifocal choroiditis, metastatic tumor, and uveal effusion. Some cases of serous retinal detachment occur as a result of central serous chorioretinopathy (CSCR). Typical CSCR generally affects healthy middle-aged males and is characterized by localized serous RD of the neurosensory retina and retinal pigment epithelium in the macula that often spontaneously improve within 2 to 3 months. On rare occasions, variant CSCR with bullous RD occurs which is frequently misdiagnosed. We report on a case of variant CSCR with severe bullous serous retinal detachment in the left eye that was initially treated at another hospital under the misdiagnosis of rhegmatogenous retinal detachment. Because the retinal detachment developed so fast that a laser could not be applied to all leaking spots, we performed a pars plana vitrectomy, pertluorocarbon liquid-assisted external drainage, and final treatment with an endolaser. The retina was well attached after this management.

Adult↗

Retinal detachment associated with atopic dermatitis.

BACKGROUND: Retinal detachment associated with atopic dermatitis, one of the most common forms of dermatitis in Japan, has markedly increased in Japan in the past 10 years. To clarify pathogenic mechanisms of retinal detachment in such cases, we retrospectively studied clinical characteristics of retinal detachment associated with atopic dermatitis. METHODS: We examined the records of 80 patients (89 eyes) who had retinal detachment associated with atopic dermatitis. The patients were classified into three groups according to lens status: group A, eyes with clear lenses (40 eyes); group B, eyes with cataract (38 eyes), and group C, aphakic or pseudophakic eyes (11 eyes). RESULTS: No significant differences were noted in the ratio of males to females, age distribution, refractive error, or characteristic of retinal detachment among the three groups. The types of retinal breaks, however, were different in eyes with and without lens changes. While atrophic holes were dominant in group A, retinal dialysis was mainly seen in groups B and C. CONCLUSION: These findings suggested that anterior vitreoretinal traction may play an important role in the pathogenesis of retinal breaks in eyes with atopic cataract and that the same pathological process may affect the formation of cataract and tractional retinal breaks in patients with atopic dermatitis.

Adolescent↗

[Management of traumatic threatened retinal detachment].

10 cases of symptomatic retinal tear and discoid edema from perforating injury are reported as traumatic threatened retinal detachments. All 10 patients were fresh cases with clear refractive media, among them were 1 case of retinal discoid edema that led to retinal detachment, subsequently cured by secondary operation, 3 cases of symptomatic retinal tear that were surrounded by photocoagulation, and 6 cases of discoid edema that were encircled by photocoagulation 'dams' to absorb the subretinal fluid for final photocoagulatory closing of the perforation. All these 9 cases were saved from retinal detachment by prophylactic photocoagulation at an early stage.

Adolescent↗

Asymptomatic rhegmatogenous retinal detachment.

The vast majority of patients with rhegmatogenous retinal detachments present with either acute or chronic symptoms. In these cases repair of the retinal detachment is almost always recommended to either improve vision or prevent further visual loss. In a small subgroup, rhegmatogenous retinal detachments were detected as incidental findings in asymptomatic patients. Such asymptomatic detachments are often caused by atrophic holes in lattice degeneration and are more commonly located in the inferior quadrants. Demarcation lines are often present. Asymptomatic retinal detachments also occur in a younger age group of patients when compared with symptomatic rhegmatogenous retinal detachments. The management of eyes with an asymptomatic retinal detachment is controversial. The risk of complications during surgical repair must be weighed against the chance that the retinal detachment will progress. Recently published clinical data suggest that the risk of progression of asymptomatic rhegmatogenous retinal detachments is small. Consequently, observation can be considered as a reasonable management option in reliable patients until progression is documented or symptoms occur. Patient education geared toward instruction on self-monitoring of the visual field and a review of the risks and benefits of retinal detachment repair versus observation are important in patients with asymptomatic retinal detachment.

Disease Progression↗

[Simultaneous bilateral rhegmatogenous retinal detachment. 7 case studies].

PURPOSE: Simultaneous bilateral rhegmatogenous retinal detachments are rare. The purpose of our study was to examine the incidence, predictive factors, surgical results and prognosis of these retinal detachments. PATIENTS AND METHODS: A retrospective analysis of the medical records of 468 consecutive patients, 7-89 years of age (mean, 45.7 years), undergoing surgery for rhegmatogenous retinal detachment between 1993 and 2000. RESULTS: During this period, a total of 497 operations for rhegmatogenous retinal detachment were done. Thirty-two patients had bilateral rhegmatogenous retinal detachment. Simultaneous detachments were observed in seven patients (1.5%). In four cases, the diagnosis of retinal detachment was fortuitous. In fact, most patients presented with unilateral symptoms. The mean age (35 years) of patients suffering from simultaneous bilateral rhegmatogenous retinal detachment was younger than that of patients with unilateral or consecutive bilateral retinal detachments. Five patients were myopic. Multiple round retinal holes were the most frequent lesions responsible for retinal detachment. A preoperative proliferative vitreoretinopathy was found in 57% of cases. The retina was reattached in nine cases (81%). CONCLUSION: Simultaneous bilateral rhegmatogenous retinal detachment is usually found in relatively young myopic patients with atrophic retinal holes. They are rare but severe because of their frequent association with preoperative proliferative vitreoretinopathy.

Adolescent↗

The induction of retinal detachment.

The induction of retinal detachment is dependent upon several factors whose relative importance remains controversial. These factors are retinal breaks, often associated with vitreous traction, inertial forces and changes in chorioretinal adhesion. Retinal breaks may be classified as holes, tears and dialyses. The relation to the vitreous base is an important prognostic indicator. Once a retinal break has occurred, inertial forces disturb the normal vitreo-retinal association. At that point, the development of a clinical detachment also depends upon loosening of the normal chorioretinal adhesion. Myopia and aphakia are important predisposing factors. The presence of preretinal membranes is a precipitating factor for recurrent retinal detachment. The high success rate of current surgical techniques (85 per cent) is mainly related to a better understanding of the mechanisms leading to retinal detachment.

Adhesiveness↗

Retinal detachments in incontinentia pigmenti.

We report on retinal detachments in six eyes of four patients with incontinentia pigmenti. These nonrhegmatogenous traction retinal detachments are characterized by extensive preretinal and vitreous fibrous organization that pull the retina anteriorly behind the lens. The clinical course and fundus appearance of the retinal detachments, beginning with the avascular peripheral retina and leading to traction retinal detachment, are similar to those of cicatricial retinopathy of prematurity. Vitreous surgery was performed on three eyes (two patients), with partial reattachment of a total retinal detachment in one eye and complete reattachment of a partial retinal detachment in a second eye. These cases represent the first successful surgical interventions reported for retinal detachment in incontinentia pigmenti.

Child↗

Functional recovery of retinal pigment epithelial damage in experimental retinal detachment.

The integrity of the RPE barrier function in retinal detachment was studied in vitro. The retinal pigment epithelium (RPE)-choroid tissue was isolated from cynomolgus monkey eyes with acute (less than 1 hr), subacute (1-2 weeks), and chronic (8-20 months) retinal detachments, and clamped between Ussing-type chambers. Electrical characteristics and choroid-to-retina permeability to carboxyfluorescein were determined. In the HEPES-buffered bathing solution, transepithelial potential difference and resistance in eyes with acute retinal detachments (0.2 mV and 134 ohm-cm2, respectively) were significantly lower than subacute (7.9 and 350) and chronic (10.4 and 348) retinal detachments. Furthermore, the permeability was increased five-fold in acute retinal detachments with respect to subacute and chronic retinal detachments, indicating a breakdown of the RPE barrier in acute retinal detachment. No statistical difference was found between subacute and chronic retinal detachments. In this animal model, RPE barrier function is destroyed at the onset of retinal detachment, but recovers in a week or two, and is maintained in the chronic stage. Histological examination revealed that RPE recovery was accomplished by RPE proliferation and hyperplasia.

Animals↗