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At least 307 records · Page 17Linked to original sources

A new technique of local anesthesia for panretinal photocoagulation.

We report a technique of local anesthetic administration used in 26 consecutive patients undergoing panretinal photocoagulation. A blunt-tipped irrigating cannula delivered 3 cc of anesthetic into the posterior sub-Tenon's space through a small opening in conjunctiva and Tenon's capsule. Immediate anesthesia, with no serious complications, was obtained in 38 of 40 eyes, facilitating administration of rapid, high-intensity laser burns. Although our experience with it is limited, we believe that this technique allows avoidance of many of the potential complications associated with the passage of a needle into the retrobulbar space.

Anesthesia, Local↗

[The filtration "pseudopad"].

Among 10 patients with primary open-angle glaucoma with a filtration "pseudo-cushion" that prevented compensation of intraocular pressure after trabeculectomy, normalization of intraocular pressure by means of medicamentous treatment (thymolol) could be achieved in 1 patient; in the rest of the patients surgical intervention was required. It is stated that the most effective is early surgical intervention: dissection of the Tenon's capsule "cyst" and resection of the episclera in the zone of the primary surgery.

Female↗

Use of GORE-TEX (polytetrafluoroethylene) in the anophthalmic socket.

The GORE-TEX soft tissue patch is composed of large open spaces surrounded by polytetrafluoroethylene (PTFE) fibers connected to nodules of solid PTFE. It was used in 12 oculoplastic surgery patients. Primary and secondary spherical silicone implants were wrapped with a GORE-TEX patch and implanted into Tenon's capsule. This study reports our first results using this versatile material.

Humans↗

[Is an implant always necessary after enucleation?].

A retrospective study was performed on 114 patients who had received an intraorbital ball implant after removal of an eye: 44 had a primary implant inserted at the time of enucleation and 70 a secondary implant, inserted at a later date. We observed distinct advantages in the primary implantation group. Patients with a primary implant, an acrylic ball covered with sclera inserted within Tenon's capsule, had better cosmetic results and a lower complication rate and fewer needed any other therapeutic measures. Of the patients with primary implants 89% did not require further treatment, as against 51% with secondary implants.

Eye Enucleation↗

[Tendon sheath of the superior oblique muscle and its measurements].

The tendon sheath of the superior oblique muscle was identified in 30 adult orbits. This sheath is composed of the fasciae of the superior levator palpebrae muscle and the superior rectus muscle and their intermuscular septum. In addition, fascia of the superior oblique and fibers of Tenon's capsule also take part. This fibrous tendon sheath is lined by a synovial layer. The width of the superior oblique muscle tendon sheath measures 2.91 +/- 0.07 mm and that of the tendon of superior oblique muscle in the sheath measures 1.35 +/- 0.23 mm, less than 1/2 of the tendon sheath, indicating the presence of a space between the two structures to facilitate movement of the tendon. The length, breadth, and the angle of reflection of the superior oblique were also measured.

Anthropometry↗

The use of a liposome-encapsulated 5-fluoroorotate for glaucoma surgery: I. Animal studies.

We have considered the wound-healing and tissue-repair process as it applies to glaucoma filtration surgery. Information derived from classical histologic studies of functioning and failed blebs has been considered in view of the new ideas based on modern cell biology concepts of the wound healing process. These evaluations provide a rationale for the use of adjunctive chemotherapy for glaucoma filtration surgery. A study is described using posterior-lip sclerectomies, an experimental monkey model, a liposomal-drug delivery system and the potent pyrimidine analog L5FO. Results of the clinical evaluation, IOP measurements, and histologic examination of L5FO treated and untreated eyes are reported. We found that the wound healing response at the surgical limbus after a posterior sclerectomy appears similar to that described for other vascularized soft tissues. The macrophage appeared to play an important role in the healing of the episcleral tissues (including Tenon's capsule and the conjunctival stroma), which proceeds rapidly resulting in the deposition of a fibrovascular scar by 2 weeks in most cases. The administration of the L5FO is highly effective in preventing the formation of such scars and thereby promoting development of functioning blebs. The administration of this wound healing retardant 1 week prior to surgery, compared to its administration at the time of surgery, shows that both methods are effective, but the use of L5FO prior to surgery is most effective. The use of the experimental monkey model described by Parrish et al offers many research opportunities to develop better adjunctive chemotherapies for glaucoma filtration surgery.

Animals↗

Effect of antineoplastic drugs on cell proliferation--individually and in combination.

Three antineoplastic agents, bleomycin, cytosine arabinoside and 5-fluorouracil, were studied individually and in combination to determine their effectiveness in controlling cell growth in the presence of fetal bovine serum. All three drugs were effective individually in specifically controlling proliferation (as measured by 3H-thymidine uptake) of human Tenon's capsule fibroblasts while bleomycin is effective at the lowest concentration. However, bleomycin alone rather than in combination with cytosine arabinoside or 5-fluorouracil was most effective in preventing division by these fibroblasts.

Animals↗

[Clinical use of orbital implant in autogenous sclera].

The authors embedded orbital implants wrapped up in autogenous sclera into 11 patients after enucleation, with sutures to fix the sclera to external ocular muscles. Tenon's capsule, and conjunctiva. The total volume of the implant was about 6 cm3 and the weight less than the eyeball. A shell was placed into the cul-de-sac after the operation to be replaced by a prosthesis 6 weeks later. No extrusion or displacement of the implants occurred in follow-ups of 6 months to 2 years and the cosmetic effect was good. Tissue tolerance and ample motility could have resulted from the scleral wrapping and suture fixation to the muscles.

Adolescent↗

[The results of cosmetic prosthesis in patients in relation to the method of formation of a moveable base for the prosthesis following removal of the eyeball].

The paper analyses remote results of cosmetic prosthesis (more than 4 months) in 107 patients with anophthalmos. For formation of the stump after enucleation different methods were used: simple enucleation; enucleation with suturing of rectus muscles to the conjunctiva of the eye ball; enucleation followed by introducing a lavsane implant into the cavity of the Tenon's capsule; evisceration followed by introducing a lavsane implant into the cavity of the scleral disc. The best results were achieved in groups of patients when enucleation was followed by plastic formation of a mobile volume stump using a vascular wicker, crimped lavsane prosthesis.

Adolescent↗

Use of Healon in eye muscle surgery with adjustable sutures.

Adhesions between the contacting surfaces of conjunctiva, Tenon's capsule, and muscle produce "tissue drag" which can complicate procedures with adjustable muscle sutures. The use of Healon is recommended to minimize this tissue drag and facilitate the "adjustment phase" of muscle surgery with adjustable muscle sutures. Data on 14 consecutive cases demonstrate the utility of Healon in adjustable strabismus surgery.

Connective Tissue↗

Trabeculectomy flap suture lysis with endolaser probe.

Enhancing filtration after trabeculectomy with scleral flap sometimes requires cutting of the nylon suture. A new use of the endolaser probe to cut the nylon suture through hemorrhagic and edematous conjunctiva and Tenon's capsule is described. The probe compresses the tissue so that it is close to the suture for delivery of the laser energy. This application of the endolaser probe as an "ecto-laser" succeeded in enhancing filtration, raising the conjunctival bleb, and lowering intraocular pressure.

Aged↗

Implant extrusion in eviscerations.

Wills Eye Hospital records for the ten-year period 1973-1983 were examined to compare the extrusion rate of implants from the scleral cavity after evisceration with the rate from Tenon's capsule after enucleation. Seventy-one consecutive extruding-implant surgical cases were examined; 60 (85%) occurred in sockets that had been previously enucleated and 11 (15%) in eviscerated eyes. In the same time period, there were 997 (95%) enucleations and 48 (5%) eviscerations. Fifteen percent of implant extrusions occurred in eviscerated sockets, for a 22% extrusion rate, compared with a 6% extrusion rate after enucleation. In this study, the frequency of extrusions was higher in eviscerations, although many variables, not taken into considerations here, might alter this ratio.

Burns, Chemical↗

Doyne Memorial Lecture, 1977. The superior oblique tendon.

New concepts concerning the anatomy of the tissues surrounding the superior oblique tendon are presented. A safe visual approach to the tendon after its penetration through Tenon's capsule is described. The various surgical procedures and techniques developed to weaken the overacting superior oblique muscles associated with A pattern and the taut superior oblique muscle found in Brown's syndrome are reviewed.

Adolescent↗

Herniated orbital fat.

Three patients with acquired orbital fat herniation are presented. Each was felt to have a dehiscence in Tenon's capsule, allowing fat to spontaneously herniate forward. Orbital fat herniation may be confused with other lesions, such as dermolipomas. The clinical features and differential diagnosis of orbital fat prolapse are discussed.

Adipose Tissue↗

Sodium hyaluronate (Healon) in glaucoma filtering procedures.

Healon (sodium hyaluronate) has been used in a prospective study designed to investigate its possible usefulness in promoting effective bleb formation and preventing cleft closure in trabeculectomy for glaucoma. One hundred fourteen patients with open-angle glaucoma were randomly assigned to one of two groups. In one group (55 patients), filtering surgery was performed without the use of Healon. In the remaining 59 patients, Healon was used to separate the iris from the cleft, the sclera from the sclera and the conjunctiva from the sclera. The surgical procedure used was the Stallard-Worst triangular modification of Cairns' method, combined with removal of the Tenon's capsule. The patients whose operations were performed with the aid of Healon had a higher success rate, as manifested by better and more permanent bleb formation and maintenance, more open clefts, less scarring, less peripheral anterior synechiae formation, and significantly lower long-term intraocular pressure. Moreover, the number of patients requiring supplemental postoperative timolol therapy was significantly smaller in the Healon group (5/59 patients: 8.5%) than in the control group (33/55 patients: 60%). There was a transient delay in the reduction of intraocular pressure following trabeculectomy in the Healon patients which was not observed in control patients. Apart from this, no adverse effects were associated with the use of Healon.

Aged↗

Clear-cornea trabeculectomy.

In most reported series of trabeculectomy results a failure rate of 10 to 15 per cent is quoted. It seems likely that some, perhaps the majority of these failures are due to conjunctival or tenon scarring. If a method of trabeculectomy could be devised so that the conjunctiva and tenon's capsule were not injured, the failure rate might be reduced. The clear-cornea approach has been developed with this in mind. The rational basis, the surgical method and results in a small number of cases will be described.

Cornea↗

[Clinical experience in glaucoma surgery utilizing silicon catheters (author's transl)].

In 7 probands exhibiting haemorrhagic glaucoma a combined thermosclerostomy with insertion of a silicons tubing (with or without basal iridectomy) has been performed. The catheter had an inner diameter of 0,5 mm, measuring about 5 mm in length and projecting about 1,5 mm into the anterior chamber. The tubing has been anchored proximally with two nylon sutures (10--0) to the corneal wound edge going through full thickness cornea; the distal end has been anchored with two more nylon sutures to underlying sclera. Tenon's capsules and conjunctiva were closed separately. In all cases the tubing has been well tolerated and did not exhibit any sign of displacement, the intracameral opening remained patent. During an observation period of 3--16 months with or without additional antiglaucomatous medication an intraocular pressure between 14--22 mm Hg could be achieved; all patients remained asymptomatic.

Adult↗

Focal pressure: a new method to encourage filtration after trabeculectomy.

One cause of failure of trabeculectomy is early closure of the sclerostomy with insufficient aqueous outflow and subsequent scarring of Tenon's capsule and conjunctiva. Ocular massage and other forms of manipulation of the scleral flap have been used in the past to enhance filtration in cases where full-thickness filtration procedures were performed, and they have been suggested for use with trabeculectomy as well. The authors propose a new method in which focal pressure is applied with an anesthetic-moistened applicator directly to the conjunctiva beside the edge of the scleral flap. This appears to be particularly indicated in trabeculectomy, and has both theoretical and practical advantages over the conventional forms of enhancing filtration in eyes having been treated with trabeculectomy. In 17 of 18 cases having trabeculectomy according to Watson's technique and in which it appeared that no filtration would develop in the postoperative period, focal pressure was successful in creating a satisfactory bleb.

Aqueous Humor↗