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Hostility during admission interview as a short-term predictor of aggression in acute psychiatric male inpatients.

BACKGROUND: A critical step for improving the prediction of on-ward violence is the identification of variables that are not only consistently associated with an increased risk of aggression but also easily evaluated during the admission interview. The goal of this prospective study was to assess the predictive utility of hostility during admission interview. METHOD: The sample consisted of 80 newly admitted male patients with heterogeneous DSM-IV psychiatric diagnoses recruited from the psychiatric ward of an urban public hospital. Psychiatric symptoms at admission were assessed with the Brief Psychiatric Rating Scale (BPRS). Aggressive behavior during the first week of hospitalization was measured with the Modified Overt Aggression Scale. Data were collected between January and June 1998. RESULTS: In a multiple regression model, BPRS items hostility and tension-excitement emerged as significant predictors of verbal aggression, whereas thinking disturbance (high) and suspiciousness-uncooperativeness (low) emerged as significant predictors of aggression against objects. In contrast, when aggression was treated as a binary dependent variable in a logistic model, hostility during the admission interview had no utility in predicting on-ward aggressive behavior. CONCLUSION: This study confirms the importance of distinguishing between different types of aggression to improve the accuracy of predictions of violence. The findings suggest that the question whether hostility is a useful short-term predictor of aggression in psychiatric inpatients cannot be answered conclusively. The predictive utility of hostility was relatively high for predicting verbal aggression but was negligible for predicting other types of aggressive behavior.

Acute Disease↗

Efficacy of aripiprazole against hostility in schizophrenia and schizoaffective disorder: data from 5 double-blind studies.

OBJECTIVE: The objective was to determine the effects of aripiprazole on hostility. METHOD: A total of 1476 patients diagnosed with DSM-IV schizophrenia or schizoaffective disorder were the subjects in 5 short-term, double-blind studies comparing aripiprazole with placebo; 3 of these studies also included a comparison with haloperidol. The studies were conducted between December 1993 and January 2001. The Positive and Negative Syndrome Scale (PANSS) was the principal outcome measure in these studies. To determine the effect of aripiprazole on hostility, post hoc analyses of the hostility item from the PANSS were conducted for the first 4 weeks of treatment. RESULTS: Aripiprazole was superior to placebo and not significantly different from haloperidol in reducing hostility. CONCLUSION: Aripiprazole is an effective treatment for hostility in patients with schizophrenia or schizoaffective disorder.

Adolescent↗

Hostility in patients with chronic constipation.

Personality changes have been reported in chronic constipation. Hostility is an important personality factor involved in psychosomatic disorders. The aim of this study was to investigate hostility in patients with chronic constipation. Sixty subjects with chronic constipation (24 males, 36 females, mean age 44.5 years) were investigated with the hostility scale of the Minnesota Multiphasic Inventory. The patients were divided in four groups according to their symptoms: functional chronic constipation (Group I, n = 18), irritable bowel syndrome expressed as chronic constipation and abdominal pain (Group II, n = 21), irritable bowel syndrome expressed as chronic constipation, abdominal pain and bloating (Group III, n = 13) and irritable bowel syndrome expressed as chronic constipation alternating with episodes of diarrhoea (Group IV, n = 8). Twenty-five clinically healthy subjects were investigated as controls. Hostility was as follows (mean +/- SD): 68 +/- 9 in group I, 62 +/- 12 in group II, 70 +/- 14 in group III, 56 +/- 12 in group IV and 40 +/- 12 in controls. The scores were significantly higher in all groups of patients with constipation versus controls (p < 0.01; < 0.001; < 0.001; < 0.02, respectively). These data suggest that hostility is increased in patients with chronic constipation. It is rather a feature of the functional bowel disorders than of constipation, as symptom, only.

Abdominal Pain↗

Absence of hostility in outpatients after administration of halazepam--a new benzodiazepine.

A number of benzodiazepine have been shown to increase hostility and aggression. This study examines whether halazepam, a new benzodiazepine structurally very similar to diazepam, is associated with increases in hostility. Fifty-one adult outpatients in a double blind, 6 week study were randomly assigned either halazepam or placebo. Hostility was measured by changes in response on four different scales, the anger-hostility factor of the Patient Symptom Checklist and three MMPI hostility scales. The results of our study indicated that halazepam does not induce significant changes in hositility.

Adult↗

Psychological correlates of blood pressure: a closer examination of hostility, anxiety, and engagement.

Recent studies by other investigators have shown that hypertensives are more hostile and anxious than normotensives. The first part of this study examined the relationship between blood pressure measured daily over a one-week period and responses to a series of questions specifically developed to distinguish hypertensives from normotensives. Responses from this sample of undergraduates did not distinguish those with high blood pressure from those with normal values. Mean resting blood pressure was related to hostility and anxiety factor scores among males but not among females. Our second study used a sample of municipal employees and examined blood pressure as a function of comparable anxiety and hostility scores as well as a trait measure of overall "engagement-involvement." More highly engaged workers were no different in anxiety or hostility than less engaged workers. There was some evidence of more variable blood pressure for the former group. It is suggested that stable personality traits such as hostility and anxiety may both precede and follow the diagnosis of blood pressure. For nurses it is important to assess the patient's general psychological profile as well as his of her emotional state at the time of measurement. Repeated blood pressure readings are recommended especially for highly engaged individuals.

Adult↗

Cardiovascular reactivity among hostile men and women: the effects of sex and anger suppression.

This study examined cardiovascular reactivity differences among hostile men and women. Sixty-four individuals (33 women 31 men; M = 19.9 years of age) were selected from a sample of 105 volunteers based on their Cook-Medley Hostility Scale scores (Cook & Medley, 1954; less than or equal to 24). Analyses revealed no significant sex differences in Cook-Medley Hostility scores. At baseline, men had higher mean systolic blood pressure (SBP) level. However, during the Stroop Color-Word Conflict Task (Stroop, 1935), high-hostile men and women exhibited similar cardiovascular responses. Further analyses revealed that cardiovascular responses to the Stroop task were differentially associated with among men and women as a function of anger suppression. For women, anger suppression was positively associated with diastolic blood pressure (DBP) responses and negatively associated with SBP responses. In contrast, anger suppression was negatively associated with DBP changes and not associated with SBP responses for men. The results suggest that personality factors, such as high hostility and anger suppression, may influence the degree to which men and women differ in their cardiovascular responses to interpersonal stressors.

Adult↗

The validity of multidimensional self-report anger and hostility measures.

The present study assessed the convergent and discriminant validity of multidimensional measures of anger and hostility and validated abbreviated neurotic and reactive hostility subscales of the Buss Durkee Hostility Inventory. A sample of 120 adults were administered the abbreviated Buss Durkee Reaction (RH) and Neurotic Hostility (NH) subscales, State-Trait Anger Scale (ST), Anger Self-Report General (ASRG) subscale, Multidimensional Anger Inventory (MAI), and Framingham Anger-in (FI), Anger-out (FO), and Discuss (FD) scales. An intercorrelation matrix supported the convergent and discriminant validity of these measures except for the Anger-in/Brood subscale of the MAI and the FO scale. Factor analysis of the scales resulted in three factors: anger experience/hostility, verbal/adaptive anger expression, and maladaptive/physical anger expression. Implications for future research on anger assessment, specifically the components of anger experience and anger expression or suppression, were discussed.

Adaptation, Psychological↗

Anger, hostility, and depression in assaultive vs. suicide-attempting males.

Hostility and depression were examined in male psychiatric patients who exhibited either assaultive (n = 40) or suicide-attempting behavior (n = 20). Both groups were compared to a sample of nonviolent males (n = 22) to provide a basis for interpreting the absolute as well as relative magnitude of these variables in relation to their violent behavior. Both suicide-attempting and assaultive patients were characterized by high levels of hostility and depression, as evidenced by significantly higher scores than those of the nonviolent group on almost all indices. Assaultive subjects evidenced relatively greater overt expression, frankly assaultive impulses, and verbalized anger and hostility. Suicide-attempting subjects tended to experience anger and hostility in a more intropunitive and covert manner and displayed higher levels of guilt and depression. Covariance analyses indicated that anger and depression contributed separately to the affective configuration of the assaultive and suicide-attempting groups.

Adult↗

Hostility as a health risk factor: relationships with neuroticism, Type A behavior, attentional focus, and interpersonal style.

In order to investigate further the psychological construct of hostility measured on the Cook-Medley (Ho) Scale as a health risk factor, the present study examined relationships between hostility assessed on the Ho Scale and several measures of neuroticism, Type A behavior, and attentional and interpersonal style, using bivariate and hierarchical multiple regression analyses. Subjects were 204 psychologically normal, physically healthy males. Significant relationships were found between hostility, neuroticism, attentional overload, and interpersonal alienation. The present study provided normative data on several important health-related psychological dimensions in a sample of healthy normals. The findings also provided further support for the relationship between the hostility construct measured on the Ho Scale and measures of neuroticism as possible dimensions of disease-prone personality.

Adult↗

The effect of quetiapine on aggression and hostility in patients with schizophrenia.

A post hoc analysis of data from three placebo-controlled, double-blind, randomized trials was carried out to determine the efficacy of quetiapine in aggression and hostility in patients with schizophrenia. Quetiapine treatment induced statistically significantly greater improvements in BPRS positive symptom cluster scores and three measures of hostility derived from the BPRS, compared with placebo, in patients symptomatic at baseline. A path analysis showed that the improvements in hostility were highly correlated with improvements in positive symptoms and there was no consistent relationship between sedation and hostility. Aggressive behaviour appears to be related to positive symptoms of schizophrenia. Quetiapine may be a suitable option for patients with schizophrenia and aggressive behaviour.

Adult↗

Hostility, coronary heart disease, and total mortality: a 33-year follow-up study of university students.

Hostility as measured by the Cook-Medley Hostility (HO) Scale on the Minnesota Multiphasic Personality Inventory has been suggested as a risk factor for coronary heart disease (CHD) and total mortality. This study tested the HO-CHD hypothesis in a sample of 1399 men who entered the University of Minnesota in 1953 and, as part of freshman orientation, completed the MMPI. Current health status was ascertained for 94% of the sample through telephone interviews 33 years later. Higher HO scores did not predict CHD mortality, CHD morbidity, or total mortality either before or after adjustment for baseline risk factors. Among the plausible explanations for these results are that (1) hostility is not a risk factor in all populations, (2) the HO scale at age 19 does not assess a stable psychological characteristic, or (3) the HO scale is not an adequate measure of hostility.

Adult↗

Instrumental and hostile aggression in childhood disruptive behavior disorders.

An analogue task of instrumental and hostile aggression during a competitive game was evaluated in a sample of clinically-referred 8- to 12-year-old aggressive boys. Similar to a prior task in a normative sample (Hoving, Wallace, & La Forme, 1979), both types of aggression increased during provocation as compared to baseline, indicating the success of the provocation manipulation, with moderate correlations between the two aggressive responses. The aggressive group with attention-deficit hyperactivity disorder (ADHD) and the aggressive group without ADHD each had higher rates of instrumental aggression than controls. Only the aggressive/ADHD group had higher rates of hostile aggression than controls. Parent Child Behavior Checklist ratings indicated a modest but significant unique relationship between instrumental aggression and delinquency. The high rate of both types of aggression in the aggressive/ADHD group suggests that comorbid ADHD and aggression may result in qualitative differences in aggressive behavior. The high rate of hostile aggression in the aggressive-ADHD group supports theoretical assumptions regarding the relationship of hostile aggression to poor impulse control.

Aggression↗

The association between anger and hostility and risk factors for coronary heart disease in children and adolescents: a review.

We reviewed the published literature on the association between anger and hostility and risk factors, both physiologic and behavioral, for coronary heart disease (CHD) in youth. The rationale for this review is based on observations that pathology and risk factors associated with CHD in adults, as well as patterns of expressing anger and hostility, often begin in childhood and adolescence; hence, it is imperative that we better understand the relationship between anger and CHD risk factors in young people if we are to develop interventions to change risk factor profiles. The first section discusses development of CHD risk factors and describes studies of the pathologic precursors of CHD that demonstrate the early age of onset for pathologic changes, the tracking of physiologic and behavioral risk factors from youth to adulthood, and the young age of initiation of behavioral risk factors associated with CHD. The second section discusses both the development and tracking of the constructs of anger and hostility. The third section provides a review of the epidemiologic studies that assess the association between anger or hostility and both physiologic and behavioral CHD risk factors among school-age children. The final section provides an analysis and synthesis of the preceding sections and makes suggestions for further research.

Adolescent↗

An exploration of the relationship between expression of hostility and the anxiety disorders.

The purpose of the present study was to investigate differences between four anxiety disorder groups with respect to their levels of hostility. Patients with diagnoses of panic disorder, agoraphobia with panic, generalized anxiety disorder and social phobia were compared as regards their performance on the Hostility and Direction of Hostility Questionnaire (HDHQ). Results showed that while the groups did not differ on their extrapunitiveness, there were significant differences on intropunitive scores, with social phobics showing the most self criticism and guilt, followed in order by the agoraphobics with panic, generalized anxiety disorder and panic disorder subjects. Scores on the Anxiety Symptoms and Consequences Scale were used to predict intropunitiveness and extrapunitiveness for each diagnostic group. Results showed that intropunitiveness was related to anxiety symptoms differently for each diagnostic group. Overall, the study indicates that intropunitive hostility may be an important feature of anxiety disorders, especially panic with and without agoraphobia, and that the finding is worth further exploration with longitudinal studies.

Adult↗

Parental hostility and its sources in psychologically abusive mothers: a test of the three-factor theory.

A revised version of the three-factor theory of child abuse (Lesnik-Oberstein, Cohen, & Koers, 1982) is presented. Further, we report on a research designed to test three main hypotheses derived from Factor I (1) (a high level of hostility in abusive parents) and its sources. The three main hypotheses are: (1) that psychologically abusive mothers have a high level of hostile feelings (Factor I); (2) that the high level of hostile feelings in abusive mothers is associated with low marital coping skills (resulting in affectionless, violent marriages), a negative childhood upbringing (punitive, uncaring, over controlling), a high level of stress (objective stress), and a high level of strain (low self-esteem, depression, neurotic symptoms, social anxiety, feelings of being wronged); and (3) that maternal psychological child abuse is associated with low marital coping skills, a negative childhood upbringing, a high level of stress and a high level of strain. Forty-four psychologically abusing mothers were compared with 128 nonabusing mothers on a variety of measures and were matched for age and educational level. All the mothers had children who were hospitalized for medical symptoms. The three hypotheses were supported, with the exception of the component of hypothesis 2 concerning the association between objective stress and maternal hostility. The positive results are consistent with the three-factor theory.

Adaptation, Psychological↗

Hostility and irritable mood in panic disorder with agoraphobia.

Twenty patients suffering from panic disorder with agoraphobia were administered the hostility subscale of Kellner's Symptom Questionnaire and the irritability scales of Paykel's Clinical Interview for Depression and of Kellner's Anxiety Rating Scale before and after behavioral treatment of agoraphobia. A matched control group of normal subjects had the same assessments at two similar points in time. Hostility and irritable mood decreased and friendliness increased in patients with panic disorder after treatment; upon recovery, there were no significant differences in hostility between patients and controls, whereas such differences were striking during the illness. The results suggest that increased hostility and irritable mood may be symptoms of panic disorder and improve with the treatment of agoraphobia.

Agoraphobia↗

An analysis of alcoholics' perception of hostility before and after treatment.

Volunteer alcoholics being treated in a chemical dependency unit (CDU) were administered the Paired Hands Test-Adult to assess their perceptions of others before and after three weeks of treatment. This test assessed the perception of others along a friendliness-hostility dimension. Test data were compared to a non-alcoholic control group who were not receiving any form of therapeutic services. The main hypothesis tested was that alcoholics experience more hostility than non-alcoholics and project this hostility through perceptual defenses. A secondary hypothesis tested was that traditional short-term therapy reduces the alcoholic's perception of hostility. Neither hypothesis was supported.

Adult↗

Hostility, depressive symptoms, and smoking in early adolescence.

Using logistic and multiple regression, we examined the association between hostility, level of depressive symptoms, and smoking in a sample of 1699 ethnically diverse students in California. Self-reports were collected twice from each student, at the beginning of the 6th and 7th grade years. Among 6th graders who had not smoked, depressive symptoms and hostility were associated with smoking initiation by the 7th grade. Among those students who had already tried smoking, increases in depressive symptoms and hostility were associated with more frequent smoking. The association between hostility and smoking was stronger for students reporting higher levels of depressive symptoms.

Adolescent↗