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[Guidelines for the sociomedical assessment of performance in patients suffering from chronic obstructive lung diseases (COPD) and bronchial asthma. II: Sociomedical assessment of performance, Annex Part B, bibliography see Part I, Gesundheitswesen 2004, 66: 263f].

The following guidelines were developed for the medical assessment services of the German Federal Insurance Institute for Salaried Employees (BfA). Starting from day-to-day practice, criteria and attributes to guide decisions for a systemisation of the sociomedical assessment of performance in chronic obstructive pulmonary diseases (COPD) and bronchial asthma were compiled. The guidelines aim at standardising the sociomedical assessment of performance and help to make the decision-making process more transparent - e. g. for the assessment of applications for decreased earning capacity benefits. Part II outlines assessment of the individual's capacity, taking occupational factors into account. Following the determination of dysfunctions the remaining abilities and disabilities, respectively, are deduced and compared with occupational demands. Finally, inferences are drawn regarding the occupational capacity of the individual.

Asthma↗

Correlations between laboratory testing and distance running performance in marathoners of similar performance ability.

Correlations between distance running performance and laboratory testing were examined in 11 marathoners of similar fitness (VO2max 66.4 +/- 1.7 ml/kg X min). They performed a graded treadmill test and a subsequent 30 km cross-country run. Heart rate, oxygen intake, blood lactate, and plasma catecholamines were measured during the treadmill test. Lactate equivalent, individual lactate threshold, 4 mmol lactate threshold, submaximum (16 km/h running velocity) lactate behavior, submaximum catecholamine responses, submaximum lactate-catecholamine product, measured VO2max, and extrapolated VO2max were examined for their adequacy in the evaluation of distance running capacity. Race times and free urine catecholamines were estimated in the field experiment. Direct correlations were found between race times and minimum lactate equivalent (r = 0.69), submaximum lactate levels (r = 0.52), submaximum catecholamine responses (r = 0.69), submaximum lactate-catecholamine product (r = 0.79), respectively. Inverse correlations were observed between race times and oxygen intake at individual lactate threshold (r = -0.68), 4 mmol lactate threshold (r = -0.76), measured VO2max (r = -0.71), and extrapolated VO2max (r = -0.63). Further correlations were found between submaximum noradrenaline and lactate behavior (r = 0.53), as well as between noradrenaline and adrenaline responses (r = 0.72). No significant correlation was observed between relative heart volumes or catecholamine excretion and race times.

Adult↗

How does the severity of a learning disability affect working memory performance?

Working memory performance was examined in children aged 11-12 years who had borderline, mild, and moderate learning disabilities. Comparisons with children of average abilities were used to determine whether those with more severe learning disabilities had greater impairments in working memory. Seven measures of working memory span were used to assess temporary phonological short-term storage (digit span, word span), temporary visuo-spatial short-term storage (pattern span, spatial span), and temporary short-term storage with additional processing, or central executive, demands (listening span. odd one out span, reverse digit span). Children with mild and moderate learning disabilities were impaired on all measures of working memory compared to children of average abilities. Children with borderline learning disabilities were just as good as children with average abilities on visuo-spatial and complex span tasks, but showed an impairment on phonological span tasks. Children with moderate learning disabilities were indistinguishable from children with mild learning disabilities on simple span tasks, but were significantly poorer than the mild group on the more demanding complex span tasks. For the group as a whole, working memory was strongly related to mental age.

Case-Control Studies↗

Relationship of pediatric overall performance category and pediatric cerebral performance category scores at pediatric intensive care unit discharge with outcome measures collected at hospital discharge and 1- and 6-month follow-up assessments.

OBJECTIVE: Given the current focus on outcomes, there is a crucial need for easily utilized measures that can effectively quantify morbidity or disability after a child's critical illness or injury. The purpose of this study is to significantly extend the research on two such promising measures: the Pediatric Overall Performance Category (POPC) and the Pediatric Cerebral Performance Category (PCPC). DESIGN: Cross-sectional analysis of a sample of pediatric intensive care unit (PICU) discharges and a prospective follow-up of this cohort of children. SETTING: Arkansas Children's Hospital. PATIENTS: Two hundred children (ranging in age from birth to 21 yrs) discharged from a PICU. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Data were collected at PICU discharge, hospital discharge, and 1- and 6-month follow-up assessments after hospital discharge. Measures utilized included the POPC (at PICU discharge), PCPC (at PICU discharge), Stanford-Binet Intelligence Scale, fourth edition (at hospital discharge), Bayley Scales of Infant Development, second edition (at hospital discharge), and the Vineland Adaptive Behavior Scales (at 1 and 6 months after discharge). Stanford-Binet Intelligence Quotients and Bayley Mental Developmental Index scores were significantly different across PCPC categories (p < .0001). Bayley Psychomotor Developmental Index scores and Vineland Adaptive Behavior Scales scores varied significantly across POPC categories (p < .0001). The test for linear trend was also significant for each of the comparisons. CONCLUSIONS: The results of this study offer additional support for the use of the PCPC and POPC. These brief and easily completed measures can provide useful information regarding probable outcomes for pediatric intensive care patients when more extensive psychometric testing is not feasible or desirable.

Adolescent↗

Hydroxyapatite high-performance liquid chromatography: column performance for proteins.

Hydroxyapatite columns for high-performance liquid chromatography that are reusable for a long time were developed; performance tests were carried out by using several types of protein. Using a high flow rate, a sharp chromatographic peak can be obtained for a homogeneous molecule. A very high level of chromatographic separation can be achieved by decreasing the slope of the gradient and increasing the total column length at the same time.

Adsorption↗

Caffeine ingestion does not alter performance during a 100-km cycling time-trial performance.

This study analyzed the effect of caffeine ingestion on performance during a repeated-measures, 100-km, laboratory cycling time trial that included bouts of 1- and 4-km high intensity epochs (HIE). Eight highly trained cyclists participated in 3 separate trials' placebo ingestion before exercise with a placebo carbohydrate solution and placebo tablets during exercise (Pl), or placebo ingestion before exercise with a 7% carbohydrate drink and placebo tablets during exercise (Cho), or caffeine tablet ingestion before and during exercise with 7% carbohydrate (Caf). Placebo (twice) or 6 mg.kg(-1) caffeine was ingested 60 min prior to starting 1 of the 3 cycling trials, during which subjects ingested either additional placebos or a caffeine maintenance dose of 0.33 mg.kg(-1) every 15 min to trial completion. The 100-km time trial consisted of five 1-km HIE after 10, 32, 52, 72, and 99 km, as well as four 4-km HIE after 20, 40, 60, and 80 km. Subjects were instructed to complete the time trial and all HIE as fast as possible. Plasma (caffeine) was significantly higher during Caf (0.43 +/- 0.56 and 1.11 +/- 1.78 mM pre vs. post Pl; and 47.32 +/- 12.01 and 72.43 +/- 29.08 mM pre vs. post Caf). Average power, HIE time to completion, and 100-km time to completion were not different between trials. Mean heart rates during both the 1-km HIE (184.0 +/- 9.8 Caf; 177.0 +/- 5.8 Pl; 177.4 +/- 8.9 Cho) and 4-km HIE (181.7 +/- 5.7 Caf; 174.3 +/- 7.2 Pl; 175.6 +/- 7.6 Cho; p <.05) was higher in Caf than in the other groups. No significant differences were found between groups for either EMG amplitude (IEMG) or mean power frequency spectrum (MPFS). IEMG activity and performance were not different between groups but were both higher in the 1-km HIE, indicating the absence of peripheral fatigue and the presence of a centrally-regulated pacing strategy that is not altered by caffeine ingestion. Caffeine may be without ergogenic benefit during endurance exercise in which the athlete begins exercise with a defined, predetermined goal measured as speed or distance.

Adult↗

Performance characteristics of bioassay, radioenzymatic assay, homogeneous enzyme immunoassay, and high-performance liquid chromatographic determination of serum gentamicin.

We compared the accuracy, precision, and between-method error of the microbiological assay, the radioenzymatic assay, the homogeneous enzyme immunoassay, and the high-performance liquid chromatographic assay for the quantitation of gentamicin in serum. Precision and accuracy were evaluated by reference samples prepared to contain 0.0 to 32.7 micrograms of gentamicin per ml. Correlations between the methods utilized patient sera with gentamicin concentrations ranging from 0.6 to 13.3 micrograms/ml. All methods were reliable within acceptable limits for routine clinical use; intermethod correlation coefficients exceeded 0.96. Relative to the microbiological assay, the alternative methods offer the advantage of rapid analysis. The elapsed times for acquiring data on a set of 10 specimens under routine operating conditions were 0.5 h by the enzyme immunoassay, 4 h by the radioenzymatic assay, 5 h by the high-performance liquid chromatographic assay, and 10 h by the microbiological assay.

Biological Assay↗

Effects of goal structures and performance contingencies on the math performance of adolescents with learning disabilities.

This study assessed the effects of assigned versus self-selected goals and contingent versus noncontingent gameplay conditions, delivered during computer-assisted math computation drill-and-practice sessions. Participants were 20 high school pupils with learning disabilities who had active Individualized Education Plan (IEP) goals that targeted the improvement of computational skills. Students were assigned randomly to goal conditions and, within goal conditions, to contingency groups. Math computation performance was measured pre-, mid-, and posttreatment. Analyses of variance indicated that students who selected their goals performed better than pupils with assigned goals. No differences existed between the contingency groups. Implications for practice are discussed.

Adolescent↗

Swimming performance of delta smelt: maximum performance, and behavioral and kinematic limitations on swimming at submaximal velocities.

Swimming performance, measured as critical swimming velocity (Ucrit) and endurance, and swimming behavior and kinematics were measured in delta smelt Hypomesus transpacificus, a threatened estuarine planktivore. Most fish (58 % of the Ucrit test group) were capable of achieving and sustaining moderately high velocities: mean Ucrit was 27.6&plusmn;5.1 cm s-1 (s.d.). Ucrit was not affected by either acclimation temperature (12&shy;21 &deg;C) or fish size (3.2&shy;6.8 cm standard length) and was generally comparable with values measured for other similarly sized fishes. The remaining 42 % of the fish failed to swim at velocities above 10&shy;15 cm s-1. Interestingly, of the fish that provided a Ucrit measurement, 62 % experienced at least one temporary swimming failure between 10 and 20 cm s-1. Endurance was highly variable and, for all velocities, not normally distributed; the only significant decrease, from 6 h to 64 min, occurred between 10 and 15 cm s-1. Kinematic analyses of stroke frequency, stroke amplitude, stride length, glide frequency, glide duration, proportion of time spent stroking and the number of strokes between successive glides showed that delta smelt employed three velocity-dependent swimming gaits: a discontinuous 'stroke-and-glide' swimming behavior below 10 cm s-1; a continuous swimming behavior above 15 cm s-1 and up to Ucrit; and a discontinuous 'burst-and-glide' swimming behavior at velocities above Ucrit. Swimming failure at velocities between 10 and 20 cm s-1 coincided with the transition from 'stroke-and-glide' swimming to continuous swimming; delta smelt were unable or unwilling to swim steadily in the flume within this transition velocity range. These results underscore the importance of monitoring and quantifying behavior in experiments intended as physiological performance tests of whole animals.

Journal Article↗

Biomechanical factors affecting performance in netball. Implications for improving performance and injury reduction.

Despite netball having one of the largest number of participants of any team game within the Commonwealth there has been limited research conducted which biomechanically analysed skills of the game. However, information presented from biomechanical analyses of skills can provide coaches with the necessary theoretical basis to teach netball fundamentals to junior players. Biomechanical information can also be used to refine the existing techniques of experienced netball players so they may achieve optimal technical performance of game skills while minimising the potential for injury. Changes to footwork rules and to the material properties of court surfaces and footwear could reduce stress placed on the musculoskeletal system. However, the factor which influences musculoskeletal stress to the greatest extent is a player's landing technique. Thus, the first concern for all netball coaches must be to teach all players to land correctly. The magnitude and rate of loading of the high vertical and horizontal ground reaction forces generated when players execute abrupt landings in netball are reduced more effectively by encouraging players to throw higher passes, requiring the receiver to jump upward to catch the ball. However, to maximise the reduction in stress placed on the musculoskeletal system on landing, players should be encouraged to land with the foot neutrally aligned (not abducted or adducted), ensure adequate hip and knee flexion, and reduce the foot-hip displacement by eliminating an exaggerated 'striding out' position often adopted by netball players. Apart from landing techniques, the only netball skill that has been objectively analysed is goal shooting. To improve shooting accuracy players should demonstrate greater flexion of the knees and shooting elbow when preparing to shoot, sufficient but not excessive hyperextension of the hand to stabilise the ball, minimisation of trunk, arm and forearm movements during the shooting action in favour of increased hand motion, greater release height and greater release velocity. If the potential for injury from poorly executed skills in netball is to be minimised, further research is required to identify the most efficient methods of performing all skills involved in the game, including pivoting, rebounding, defensive movement patterns, and attacking movement strategies.

Athletic Injuries↗

Left- versus right-hand tracking performance by right-handed boys and girls: examination of performance asymmetry.

This study compared left- versus right-hand performance within healthy, right-handed, 8- or 9-yr.-old boys and girls on a finger-movement tracking task. 38 boys and 38 girls were randomly assigned to use either the left hand first and right hand second or vice versa in tracking a sine wave target with extension and flexion movements of the index finger. The data were analyzed with a three-way analysis of variance with repeated measures followed by pair-wise comparisons with a Bonferroni correction. Analysis yielded a significant hand x test interaction and a significant improvement for subjects tracking with the right hand on Test 1 and left hand on Test 2. No significant change occurred for subjects tracking with the left hand on Test 1 and right hand on Test 2. No interaction was observed with sex as a factor. This study suggests that asymmetry of performance favoring the left hand occurs in right-handed boys and girls during finger-movement tracking.

Child↗

Student leaders and social performance as measured by the social performance survey schedule.

There is a paucity of research on the social skills of student leaders, although studies have been conducted on other groups of students and adults. In this study, the Social Performance Survey Schedule was administered to 114 student leaders in Grades 6 to 11. Consistent with previous research applying the survey on diverse populations, girls engaged in more positive social behaviors, fewer negative behaviors, and had higher over-all performance than boys. Suggestions for those who may have contact with such students were made.

Adolescent↗

Effects of ractopamine, genotype, and growth phase on finishing performance and carcass value in swine: I. Growth performance and carcass merit.

A replicated factorial experiment using 183 individually fed crossbred barrows was conducted. Pigs were fed an 18.5% CP (.95% lysine) diet with 3,594 kcal of ME/kg. The effects of five genotypes (GT): 1) Hampshire (H) x (H x Duroc [D]), 2) synthetic terminal sire line, 3) (H x D) x (Landrace [L] x [Yorkshire (Y) x D]), 4) L x (Y x D), and 5) Y x L; two levels of ractopamine (RAC) treatment: 0 and 20 ppm; and three treatment weight periods (WT): 1) 59 to 100, 2) 73 to 114, and 3) 86 to 127 kg live weight on growth performance and carcass traits were evaluated. Ractopamine increased (P less than .0001) amount (FSL) and percentage (PFSL) of carcass lean standardized to 10% fat content, loin eye area (LEA), and dressing percentage (PDRES) and reduced (P less than .01) amount (DF) and percentage (PDF) of dissected fat. Magnitudes of RAC effects were smaller than those reported by other researchers. Effects of GT and WT on all growth and carcass traits were highly significant (P less than .001) except for those of WT on ADG (P less than .05) and GT on average feed intake (AFI) and backfat thickness at the last rib (BFLR; P less than .05). Genotype 3 performed better for most economically important traits than did GT 1 and 4, suggesting that heterosis existed in GT 3, which essentially was obtained by crossing GT 1 and 4. Among the three treatment periods, WT 2 had the highest ADG. As BW increased from WT 1 to 3, AFI and AFI/ADG ratio (FCR) increased and lean percentage decreased.(ABSTRACT TRUNCATED AT 250 WORDS)

Adipose Tissue↗

Effects of supplemental fat on growth performance and quality of beef from steers fed barley-potato product finishing diets: I. Feedlot performance, carcass traits, appearance, water binding, retail storage, and palatability attributes.

To measure the effects of dietary fat on feedlot performance, carcass characteristics, and beef appearance, moisture binding, shelf life, and palatability, 168 crossbred beef steers (317 +/- 1.0 kg) were allotted randomly, within weight blocks, to a randomized complete block design with a 3 x2 + 1 factorial arrangement of dietary treatments. Main effects were level of yellow restaurant grease (RG; 0, 3, or 6%) and level of alfalfa hay (AH; 3.5 or 7%), with the added treatment of 6% tallow and 7% AH in barley-based diets containing 15% potato by-product and 7% supplement fed for 165 d (all dietary levels on a DM basis). Dietary treatment did not (P >0.10) affect DMI, LM area, beef brightness, or beef texture. Level of RG linearly increased (P <0.05) ADG from 1.48 to 1.60 kg/d, diet NE(m) from 2.4 to 2.6 Mcal/kg, diet NE(g) from 1.7 to 1.9 Mcal/kg, and internal fat from 2.1 to 2.4%. Level of RG linearly increased (P <0.05) G:F from 0.184 to 0.202, but decreased (P <0.05) beef firmness score from 3.0 to 2.8 and fat luster score from 3.1 to 2.8. Level of AH did not (P >0.10) affect any of the measurements; however, AH interacted with level of RG on fat thickness and yield grade (linear; P <0.05), as well as marbling score and percentage of carcasses grading USDA Choice (quadratic; P <0.05). Fat thickness and yield grade increased with increasing RG level in 3.5%, but not in 7%, AH diets. In steers fed 3.5% RG, marbling scores and percentage of carcasses grading Choice were greatest when fed with 3.5% AH, and least when fed 7% AH. Steers fed tallow had lower marbling scores (P = 0.01) and percentage of carcasses grading Choice (P = 0.066) than those fed RG. Retail storage attributes, including visual and instrumental color, decreased during storage (P <0.01), but were not (P >0.10) affected by diet. Trained sensory panel scores for initial tenderness increased quadratically (P = 0.07) as dietary RG increased, but diet did not (P >0.10) affect drip loss, cooking loss, or trained sensory panel scores for sustained tenderness, initial and sustained juiciness, and beef flavor. Therefore, RG increased diet energy, improved performance, and increased carcass fatness; however, dietary fat and AH did not affect most measurements of water retention, color stability, or palatability of beef.

Animal Feed↗

Reciprocal recurrent selection for 21-day litter weight of crossbred gilts. II. Reproductive performance of purebred females producing purebred and two-way cross litters and performance of purebred and crossbred pigs.

This paper reports estimates of correlated genetic change in reproductive performance of purebred gilts producing two-way cross litters and purebred sows producing purebred litters as well as postweaning performance of two-way cross and purebred pigs produced during reciprocal recurrent selection (RRS) between Line 8 (Duroc) and Line 9 (Beltsville No. 1) for 21-d litter weight production of crossbred gilts. A randomly mated control line developed from a crossbred foundation was maintained to monitor environmental change. Data were adjusted for age of dam, inbreeding of dam, inbreeding of litter (or pig) and linear and quadratic effects of day born within season. The traits evaluated were: litter size, litter weight and average pig weight/litter at birth and weaning (42 d); postweaning average daily gain; age at 90.7 kg and backfat thickness at 90.7 kg. Two data sets were analyzed; the first set included seven seasons of data with purebred gilts producing two-way cross litters, and the second set included seven seasons of data with purebred sows producing purebred litters. No estimates of environmental trend were significant in either set of data. In the first data set, only the estimate of genetic change in backfat thickness of two-way cross pigs was significant and it was in the desired direction. All other estimates were small and did not approach significance. In the second data set, estimates of genetic trend were greater in Line 9 than in Line 8.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Organizational factors differentiating high performing from low performing supported employment programs.

This study sought to uncover the factors that contributed to differences in competitive employment rates for adults with severe mental illness between high and low performing programs. The five programs with the highest competitive employment rates were compared to the four lowest performing programs. Using qualitative methods, researchers used site visits and in-depth interviews with program directors and supervisors, consumers, and front line staff. Using a combination of constant comparative methods and content analysis, the study found notable and consistent differences between the two groups in administrative practices and the roles of ease managers and therapists. The role of administration has been largely overlooked in the supported work literature yet it may be the administrator's efforts to shape an organizational culture that is the driving force behind the implementation of evidence-based structures and practices.

Adult↗

Medicaid program; Medicaid Management Information System (MMIS) performance review; notification procedures for changes in requirements, performance standards, and reapproval conditions--HCFA. Final rule.

This rule eliminates the requirement in the Medicaid regulations that HCFA meet certain Federal Register notification requirements for any changes in performance standards and other conditions for reapproval of State Medicaid Management Information Systems (MMISs), even if such Federal Register notice would not otherwise be required. An independent Federal Register publication requirement will remain in place with respect to changes in system requirements and other conditions for approval of MMISs. We believe that a revised process for notifying States and other concerned parties of changes in performance standards and other conditions of reapproval is appropriate and will facilitate the efficient issuance of revised MMIS review requirements and methodologies each year.

Centers for Medicare and Medicaid Services, U.S.↗

Assay of tinidazole in human serum by high-performance thin-layer chromatography--comparison with high-performance liquid chromatography.

Determination of tinidazole in human serum by high-performance thin-layer chromatography (HPTLC) is presented. It includes use of 10 x 10 cm plates coated with silica gel 60 and chloroform-acetonitrile-acetic acid (60 + 40 + 2) as mobile phase. Quantitation was performed by densitometry at 320 nm. The linearity (1-10 ng), precision (6%), reproducibility (5%), recovery (96%), and detection limit (1 mg/L) of tinidazole determination by HPTLC were comparable with corresponding method parameters by reversed-phase HPLC. A satisfactory correlation was found between the 2 analytical methods. The procedure was used to quantitate tinidazole in patient sera.

Antitrichomonal Agents↗